LOCUS       NM_015512              13105 bp    mRNA    linear   PRI 11-OCT-2024
DEFINITION  Homo sapiens dynein axonemal heavy chain 1 (DNAH1), mRNA.
ACCESSION   NM_015512
VERSION     NM_015512.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 13105)
  AUTHORS   Wilken,A., Hoben,I.M., Wolter,A., Loges,N.T., Olbrich,H., Aprea,I.,
            Dworniczak,B., Raidt,J. and Omran,H.
  TITLE     Primary Ciliary Dyskinesia Associated Disease-Causing Variants in
            CCDC39 and CCDC40 Cause Axonemal Absence of Inner Dynein Arm Heavy
            Chains DNAH1, DNAH6, and DNAH7
  JOURNAL   Cells 13 (14), 1200 (2024)
   PUBMED   39056782
  REMARK    GeneRIF: Primary Ciliary Dyskinesia Associated Disease-Causing
            Variants in CCDC39 and CCDC40 Cause Axonemal Absence of Inner
            Dynein Arm Heavy Chains DNAH1, DNAH6, and DNAH7.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13105)
  AUTHORS   Long,S., Fu,L., Ma,J., Yu,H., Tang,X., Hu,T., Han,W., Liu,W.,
            Liao,H., Fu,T., Huang,G., Lu,W. and Lin,T.
  TITLE     Novel biallelic variants in DNAH1 cause multiple morphological
            abnormalities of sperm flagella with favorable outcomes of
            fertility after ICSI in Han Chinese males
  JOURNAL   Andrology 12 (2), 349-364 (2024)
   PUBMED   37302001
  REMARK    GeneRIF: Novel biallelic variants in DNAH1 cause multiple
            morphological abnormalities of sperm flagella with favorable
            outcomes of fertility after ICSI in Han Chinese males.
REFERENCE   3  (bases 1 to 13105)
  AUTHORS   Dacheux,D., Martinez,G., Broster Reix,C.E., Beurois,J., Lores,P.,
            Tounkara,M., Dupuy,J.W., Robinson,D.R., Loeuillet,C., Lambert,E.,
            Wehbe,Z., Escoffier,J., Amiri-Yekta,A., Daneshipour,A.,
            Hosseini,S.H., Zouari,R., Mustapha,S.F.B., Halouani,L., Jiang,X.,
            Shen,Y., Liu,C., Thierry-Mieg,N., Septier,A., Bidart,M., Satre,V.,
            Cazin,C., Kherraf,Z.E., Arnoult,C., Ray,P.F., Toure,A.,
            Bonhivers,M. and Coutton,C.
  TITLE     Novel axonemal protein ZMYND12 interacts with TTC29 and DNAH1, and
            is required for male fertility and flagellum function
  JOURNAL   Elife 12, 87698 (2023)
   PUBMED   37934199
  REMARK    GeneRIF: Novel axonemal protein ZMYND12 interacts with TTC29 and
            DNAH1, and is required for male fertility and flagellum function.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 13105)
  AUTHORS   Wang,M., Yang,Q.Y., Zhou,J.P., Tan,H.P., Hu,J., Jin,L. and Zhu,L.X.
  TITLE     Novel compound heterozygous mutations in DNAH1 cause primary
            infertility in Han Chinese males with multiple morphological
            abnormalities of the sperm flagella
  JOURNAL   Asian J Androl 25 (4), 512-519 (2023)
   PUBMED   36510862
  REMARK    GeneRIF: Novel compound heterozygous mutations in DNAH1 cause
            primary infertility in Han Chinese males with multiple
            morphological abnormalities of the sperm flagella.
REFERENCE   5  (bases 1 to 13105)
  AUTHORS   Zuccarello,D., Ferlin,A., Cazzadore,C., Pepe,A., Garolla,A.,
            Moretti,A., Cordeschi,G., Francavilla,S. and Foresta,C.
  TITLE     Mutations in dynein genes in patients affected by isolated
            non-syndromic asthenozoospermia
  JOURNAL   Hum Reprod 23 (8), 1957-1962 (2008)
   PUBMED   18492703
  REMARK    GeneRIF: Male carriers of the mutations always exhibit
            asthenozoospermia, whereas female carriers manifest no alterations
            in either fertility or pulmonary clearance.
REFERENCE   6  (bases 1 to 13105)
  AUTHORS   Neesen,J., Kirschner,R., Ochs,M., Schmiedl,A., Habermann,B.,
            Mueller,C., Holstein,A.F., Nuesslein,T., Adham,I. and Engel,W.
  TITLE     Disruption of an inner arm dynein heavy chain gene results in
            asthenozoospermia and reduced ciliary beat frequency
  JOURNAL   Hum Mol Genet 10 (11), 1117-1128 (2001)
   PUBMED   11371505
REFERENCE   7  (bases 1 to 13105)
  AUTHORS   Neesen,J., Koehler,M.R., Kirschner,R., Steinlein,C.,
            Kreutzberger,J., Engel,W. and Schmid,M.
  TITLE     Identification of dynein heavy chain genes expressed in human and
            mouse testis: chromosomal localization of an axonemal dynein gene
  JOURNAL   Gene 200 (1-2), 193-202 (1997)
   PUBMED   9373155
REFERENCE   8  (bases 1 to 13105)
  AUTHORS   Chapelin,C., Duriez,B., Magnino,F., Goossens,M., Escudier,E. and
            Amselem,S.
  TITLE     Isolation of several human axonemal dynein heavy chain genes:
            genomic structure of the catalytic site, phylogenetic analysis and
            chromosomal assignment
  JOURNAL   FEBS Lett 412 (2), 325-330 (1997)
   PUBMED   9256245
REFERENCE   9  (bases 1 to 13105)
  AUTHORS   Vaughan,K.T., Mikami,A., Paschal,B.M., Holzbaur,E.L., Hughes,S.M.,
            Echeverri,C.J., Moore,K.J., Gilbert,D.J., Copeland,N.G.,
            Jenkins,N.A. and Vallee,R.B.
  TITLE     Multiple mouse chromosomal loci for dynein-based motility
  JOURNAL   Genomics 36 (1), 29-38 (1996)
   PUBMED   8812413
REFERENCE   10 (bases 1 to 13105)
  AUTHORS   Zariwala,M.A., Knowles,M.R. and Leigh,M.W.
  TITLE     Primary Ciliary Dyskinesia
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   20301301
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AB037831.3, DN831799.1 and
            AW016677.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Jun 2, 2019 this sequence version replaced NM_015512.4.
            
            Summary: This gene encodes an inner dynein arm heavy chain that
            provides structural support between the radial spokes and the outer
            doublet of the sperm tail. Naturally occurring mutations in this
            gene are associated with primary ciliary dyskinesia and multiple
            morphological anomalies of the flagella that result in
            asthenozoospermia and male infertility. Mice with a homozygous
            knockout of the orthologous gene are viable but have reduced sperm
            motility and are infertile. [provided by RefSeq, Feb 2017].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB037831.3 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2144333
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000420323.7/ ENSP00000401514.2
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-11141             AB037831.3         1-11141
            11142-11229         DN831799.1         451-538
            11230-13104         AB037831.3         11230-13104
            13105-13105         AW016677.1         22-22               c
FEATURES             Location/Qualifiers
     source          1..13105
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3p21.1"
     gene            1..13105
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /note="dynein axonemal heavy chain 1"
                     /db_xref="GeneID:25981"
                     /db_xref="HGNC:HGNC:2940"
                     /db_xref="MIM:603332"
     exon            1..227
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            228..594
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     CDS             262..13059
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /note="dynein heavy chain 1, axonemal; dynein, axonemal,
                     heavy polypeptide 1; ciliary dynein heavy chain 1; heat
                     shock regulated protein 1; axonemal beta dynein heavy
                     chain 1; testicular tissue protein Li 60"
                     /codon_start=1
                     /product="dynein axonemal heavy chain 1"
                     /protein_id="NP_056327.4"
                     /db_xref="CCDS:CCDS46842.1"
                     /db_xref="GeneID:25981"
                     /db_xref="HGNC:HGNC:2940"
                     /db_xref="MIM:603332"
                     /translation="MEQPNSKGYSLGRTPQGPECSSAPAVQVGTHRGLEYNPGKILPG
                     SDYGLGNPPALDPKLPHLPLPPAPPTLSDLGQPRKSPLTGTDKKYPLMKQRGFYSDIL
                     SPGTLDQLGEVCRGPRMSQNLLRQADLDKFTPRVGSFEVPEDFQERMEQQCIGSTTRL
                     LAQTDFPLQAYEPKMQVPFQVLPGQHPRKIEIERRKQQYLSLDIEQLLFSQGIDSNKL
                     MPRHLDHQHPQTIEQGHDPIFPIYLPLKVFDNEDFDCRTPREWINMGLEPGSLDRKPV
                     PGKALLPTDDFLGHEDPKSQKLKYKWCEVGVLDYDEEKKLYLVHKTDEKGLVRDEMGR
                     PILNAGVTTEGRPPLQVCQYWVPRIQLLFCAEDPCMFAQRVVQANALRKNTEALLLYN
                     LYVDCMPSDGQHVISEQSLSKIKQWALSTPRMRKGPSVLEHLSSLAREVSLDYERSMN
                     KINFDHVVSSKPETFSYVTLPKKEEEQVPERGLVSVPKYHFWEQKEDFTFVSLLTRPE
                     VITALSKVRAECNKVTAMSLFHSSLSKYSHLEEFEQIQSQTFSQVQMFLKDSWISSLK
                     VAMRSSLRDMSKGWYNLYETNWEVYLMSKLRKLMELVKYMLQDTLRFLVQDSLASFSQ
                     FISDTCCSVLNCTDDMVWGDDLINSPYRPRKNPLFIMDLVLDSSGVHYSTPLEQFEAS
                     LLNLFDKGILATHAVPQLEKLVMEDIFISGDPLLESVGLHEPLVEELRATIASAVSKA
                     MIPLQAYAKEYRKYLELNNNDIASFLKTYQTQGLLAQEVREVVLTHLREKEILDSSLP
                     SSIIIGPFYINTDNVKQSLSKKRKALATSVLDILAKNLHKEVDSICEEFRSISRKIYE
                     KPNSIEELAELREWMKGIPERLVGLEERIVKVMDDYQVMDEFLYNLSSDDFNDKWIAS
                     NWPSKILGQIELVQQQHVEDEEKFRKIQIMDQNNFQEKLEGLQLVVAGFSIHVEISRA
                     HEIANEVRRVKKQLKDCQQLAMLYNNRERIFSLPITNYDKLSRMVKEFQPYLDLWTTA
                     SDWLRWSESWMNDPLSAIDAEQLEKNVVEAFKTMHKCVKQFKDMPACQEVALDIRARI
                     EEFKPYIPLIQGLRNPGMRIRHWETLSNQININVRPKANLTFARCLEMNLQDHIESIS
                     KVAEVAGKEYAIEQALDKMEKEWSTILFNVLPYKATDTYILKSPDEASQLLDDHIVMT
                     QNMSFSPYKKPFEQRINSWENKLKLTQEVLEEWLNCQRSWLYLEPIFSSEDINQQLPV
                     ESKRYQTMERIWKKIMKNAYENREVINVCSDLRMLDSLRDCNKILDLVQKGLSEYLET
                     KRSAFPRFYFLSDDELLEILSQTKDPTAVQPHLRKCFENIARLLFQEDLEITHMYSAE
                     GEEVQLCFSIYPSSNVEDWLREVERSMKASVHDIIEKAIRAYPTMPRTQWVLNWPGQV
                     TIAGCQTYWTMEVAEALEAGNLRSQLFPQLCQQLSDLVALVRGKLSRMQRAVLSALIV
                     IEVHAKDVVSKLIQENVVSVNDFQWISQLRYYWTNNDLYIRAVNAEFIYGYEYLGNSG
                     RLVITPLTDRCYLTLTGALHLKFGGAPAGPAGTGKTETTKDLGKALAIQTVVFNCSDQ
                     LDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVAQQITTIQKAQQQRVERFMFEG
                     VEIPLVPSCAVFITMNPGYAGRTELPDNLKALFRPVAMMVPDYAMITEISLYSFGFNE
                     ASVLAKKITTTFKLSSEQLSSQDHYDFGMRAVKTVISAAGNLKRENPSMNEELICLRA
                     IRDVNVPKFLQEDLKLFSGIVSDLFPTIKEEDTDYGILDEAIREACRNSNLKDVEGFL
                     TKCIQLYETTVVRHGLMLVGPTGSGKSTCYRVLAAAMTSLKGQPSISGGMYEAVNYYV
                     LNPKSITMGQLYGEFDLLTHEWTDGIFSSFIRAGAITSDTNKKWYMFDGPVDAIWIEN
                     MNTVLDDNKKLCLSSGEIIKLTEAMTMMFEVQDLAVASPATVSRCGMVYLEPSILGLM
                     PFIECWLRKLPPLLKPYEEHFKALFVSFLEESISFVRSSVKEVIASTNCNLTMSLLKL
                     LDCFFKPFLPREGLKKIPSEKLSRIVELIEPWFIFSLIWSVGATGDSSGRTSFSHWLR
                     LKMENEQLTLLFPEEGLVFDYRLEDAGISGTNDSEDEEEEYKQVAWVKWMDSSAPFTM
                     VPDTNYCNIIVPTMDTVQMSHLLDMLLTNKKPVLCIGPTGTGKTLTISDKLLKNLALD
                     YISHFLTFSARTSANQTQDFIDSKLDKRRKGVFGPPLGRNFIFFIDDLNMPALETYGA
                     QPPIELLRQWMDHGGWYDRKIIGAFKNLVDINFVCAMGPPGGGRNTVTPRLMRHFNYL
                     SFAEMDEVSKKRIFSTILGNWLDGLLGEKSYRERVPGAPHIAHFTEPLVEATIMVYAT
                     ITSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPAKVEDQVQLLRLWYHENCRVFRDRL
                     VNEEDRSWFDQLLKRCMEQWEVTFNKVCPFQPILYGDFMSPGSDVKSYELITSESKMM
                     QVIEEYIEDYNQINTAKLKLVLFMDAMSHICRISRTLRQALGNALLLGVGGSGRSSLT
                     RLASHMAEYECFQIELSKNYGMSEWRDDVKKVLLKAGLQNLPITFLFSDTQIKNESFL
                     EDINNVLNSGDIPNLYTADEQDQIVSTMRPYIQEQGLQPTKANLMAAYTGRVRSNIHM
                     VLCMSPIGEVFRARLRQFPSLVNCCTIDWFNEWPAEALKSVATVFLNEIPELESSQEE
                     IQGLIQVCVYIHQSVSKKCIEYLAELTRHNYVTPKSYLELLHIFSILIGQKKLELKTA
                     KNRMKSGLDKLLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTMEQIKVDTAIAEETRN
                     SVQTEEIKANEKAKKAQAIADDAQKDLDEALPALDAALASLRNLNKNDVTEVRAMQRP
                     PPGVKLVIEAVCIMKGIKPKKVPGEKPGTKVDDYWEPGKGLLQDPGHFLESLFKFDKD
                     NIGDVVIKAIQPYIDNEEFQPATIAKVSKACTSICQWVRAMHKYHFVAKAVEPKRQAL
                     LEAQDDLGVTQRILDEAKQRLREVEDGIATMQAKYRECITKKEELELKCEQCEQRLGR
                     AGKLINGLSDEKVRWQETVENLQYMLNNISGDVLVAAGFVAYLGPFTGQYRTVLYDSW
                     VKQLRSHNVPHTSEPTLIGTLGNPVKIRSWQIAGLPNDTLSVENGVINQFSQRWTHFI
                     DPQSQANKWIKNMEKDNGLDVFKLSDRDFLRSMENAIRFGKPCLLENVGEELDPALEP
                     VLLKQTYKQQGNTVLKLGDTVIPYHEDFRMYITTKLPNPHYTPEISTKLTLINFTLSP
                     SGLEDQLLGQVVAEERPDLEEAKNQLIISNAKMRQELKDIEDQILYRLSSSEGNPVDD
                     MELIKVLEASKMKAAEIQAKVRIAEQTEKDIDLTRMEYIPVAIRTQILFFCVSDLANV
                     DPMYQYSLEWFLNIFLSGIANSERADNLKKRISNINRYLTYSLYSNVCRSLFEKHKLM
                     FAFLLCVRIMMNEGKINQSEWRYLLSGGSISIMTENPAPDWLSDRAWRDILALSNLPT
                     FSSFSSDFVKHLSEFRVIFDSLEPHREPLPGIWDQYLDQFQKLLVLRCLRGDKVTNAM
                     QDFVATNLEPRFIEPQTANLSVVFKDSNSTTPLIFVLSPGTDPAADLYKFAEEMKFSK
                     KLSAISLGQGQGPRAEAMMRSSIERGKWVFFQNCHLAPSWMPALERLIEHINPDKVHR
                     DFRLWLTSLPSNKFPVSILQNGSKMTIEPPRGVRANLLKSYSSLGEDFLNSCHKVMEF
                     KSLLLSLCLFHGNALERRKFGPLGFNIPYEFTDGDLRICISQLKMFLDEYDDIPYKVL
                     KYTAGEINYGGRVTDDWDRRCIMNILEDFYNPDVLSPEHSYSASGIYHQIPPTYDLHG
                     YLSYIKSLPLNDMPEIFGLHDNANITFAQNETFALLGTIIQLQPKSSSAGSQGREEIV
                     EDVTQNILLKVPEPINLQWVMAKYPVLYEESMNTVLVQEVIRYNRLLQVITQTLQDLL
                     KALKGLVVMSSQLELMAASLYNNTVPELWSAKAYPSLKPLSSWVMDLLQRLDFLQAWI
                     QDGIPAVFWISGFFFPQAFLTGTLQNFARKFVISIDTISFDFKVMFEAPSELTQRPQV
                     GCYIHGLFLEGARWDPEAFQLAESQPKELYTEMAVIWLLPTPNRKAQDQDFYLCPIYK
                     TLTRAGTLSTTGHSTNYVIAVEIPTHQPQRHWIKRGVALICALDY"
     exon            595..667
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            668..842
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            843..999
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1000..1132
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1133..1294
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1295..1547
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1548..1705
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1706..1917
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1918..2216
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2217..2367
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2368..2561
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2562..2787
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2788..2907
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2908..2990
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2991..3132
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            3133..3288
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            3289..3487
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            3488..3741
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            3742..3954
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            3955..4119
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            4120..4241
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            4242..4347
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            4348..4527
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            4528..4668
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            4669..4832
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            4833..4946
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            4947..5135
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            5136..5241
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            5242..5355
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            5356..5505
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            5506..5592
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            5593..5779
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            5780..5871
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            5872..6026
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            6027..6204
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            6205..6399
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            6400..6519
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            6520..6678
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            6679..6786
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            6787..6927
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            6928..7088
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            7089..7246
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            7247..7420
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            7421..7459
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            7460..7638
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            7639..7869
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            7870..8066
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            8067..8202
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            8203..8411
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            8412..8583
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            8584..8775
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            8776..8886
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            8887..9072
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            9073..9264
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            9265..9432
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            9433..9624
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            9625..9756
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            9757..9882
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            9883..10002
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            10003..10152
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            10153..10313
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            10314..10539
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            10540..10735
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            10736..10887
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            10888..11084
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            11085..11229
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            11230..11388
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            11389..11520
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            11521..11691
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            11692..11871
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            11872..12048
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            12049..12219
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            12220..12350
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            12351..12702
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            12703..12937
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            12938..13105
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      13083..13088
                     /regulatory_class="polyA_signal_sequence"
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /note="hexamer: ATTAAA"
     polyA_site      13105
                     /gene="DNAH1"
                     /gene_synonym="CILD37; DNAHC1; HDHC7; HL-11; HL11; HSRF-1;
                     SPGF18; XLHSRF-1"
                     /note="major polyA site"
ORIGIN      
        1 ggggggtacc caacctatac gcagacccat tgagcagcca gactgcccta aacagggcta
       61 tggagtcctt gtcccttcta agagctgtgg acaccttgcc tccagttccc ctcacagtcc
      121 tttcttcctt ctgcagtgat cactgagtac ctgtgtgaat gccaacaaga aaaataaaac
      181 cacagtttgg attcaggaaa ggttgcacca ccatcaggtc ttgaagggag cttcggctgg
      241 ggcatctccc tgagaagcag catggagcag cctaacagta aaggctatag cctgggaagg
      301 acccctcagg gcccagagtg cagcagtgct cctgcagtcc aagtggggac ccacaggggc
      361 ctagagtata acccggggaa gattcttcca ggatcagact atgggttggg aaatcctcca
      421 gcccttgacc ccaagctccc acatttaccc ctgcccccgg ccccacccac actctcagac
      481 ttggggcagc cacggaagtc acccctgaca ggcactgata agaagtaccc gctgatgaag
      541 cagcgtgggt tctactccga catcctcagc cctggaacct tagatcaact tggggaggta
      601 tgtcgtggcc cccgaatgag ccagaacctc ctgcggcagg ctgaccttga caagttcacc
      661 ccaagagtcg gaagctttga ggttcctgaa gacttccagg agcgcatgga gcagcagtgc
      721 atcgggtcca ccacccggct gctcgcccag actgacttcc cactgcaggc ctacgagccc
      781 aagatgcagg tgcctttcca ggtgctgcca ggccagcatc ctcgcaagat tgagatcgag
      841 aggaggaaac agcagtacct gagcctggac attgagcagt tgctgttcag ccagggcatc
      901 gactccaaca agctcatgcc caggcacctg gaccaccagc acccccaaac catcgaacag
      961 ggccatgacc caatcttccc catctacctc ccactgaagg tatttgacaa tgaggacttt
     1021 gactgccgga ctcccagaga gtggatcaac atgggcttgg agccagggtc tctggacagg
     1081 aaacctgtcc cgggaaaagc cctcttgccc actgatgact tcctggggca tgaggacccc
     1141 aagagtcaga agctgaagta caaatggtgc gaggtcggcg tcctggacta cgacgaggag
     1201 aagaagctat acctggtaca caagacagac gagaaaggcc tggtgcgaga tgagatgggg
     1261 aggcccatcc tgaatgcagg ggtcaccact gaaggaaggc caccccttca ggtctgtcag
     1321 tactgggtgc cacggatcca gcttctcttc tgcgctgagg acccttgcat gttcgcacaa
     1381 cgtgtggtcc aggccaacgc cctgcgcaag aacacggaag cactgctgct ctacaacttg
     1441 tatgtggact gcatgccctc tgacggccag catgtcatca gtgaacagag cctgagcaag
     1501 atcaagcagt gggccctgag cacgcctcgg atgcgcaaag gcccctcggt tctagagcac
     1561 ctcagcagtc ttgccagaga agtgagcctg gactatgagc gcagcatgaa caagatcaac
     1621 tttgaccacg ttgtctcttc caagcccgag accttctcct acgtcaccct ccccaagaag
     1681 gaggaggagc aggtgcctga gcgagggctg gtgagtgtcc ccaagtacca cttctgggag
     1741 cagaaggagg acttcacttt cgtgtccctg ctcacacggc cagaggtcat cacggccctc
     1801 agcaaggtga gggccgagtg caacaaggtg accgccatgt ccctgttcca ctcgagcctc
     1861 tccaagtaca gccacctgga ggaatttgag cagatccagt cacagacctt ctcccaggtg
     1921 cagatgttcc tcaaggacag ctggatcagc tcgctaaagg tggccatgcg cagcagcctg
     1981 cgcgacatga gcaagggctg gtacaacctc tacgagacca actgggaggt gtacctcatg
     2041 tccaagctgc gcaagctgat ggagctggtg aagtacatgc tgcaggacac actgcgcttc
     2101 ctggtgcagg actcacttgc cagcttctca cagttcatca gcgacacctg ttgcagcgtg
     2161 ctcaactgca ccgatgacat ggtctggggt gacgacttaa ttaacagccc ctacaggccc
     2221 cggaagaatc ccctgttcat catggacctg gtgctggaca gctctggggt gcactatagc
     2281 accccactgg agcagtttga ggcatctctg ctgaacctct tcgacaaggg catcctggcc
     2341 acccatgccg tgccccagct ggagaagctg gtgatggagg acatcttcat cagcggtgac
     2401 cccctgctgg agtccgtggg ccttcatgag ccactggtgg aagagctacg ggccaccatt
     2461 gccagtgccg tgtccaaggc catgatccca ctgcaggcct acgccaagga gtaccgaaag
     2521 tacctggagc tgaacaacaa tgacattgcc tcctttctca aaacctacca gacgcagggc
     2581 ctgttggccc aggaggtgcg ggaggtagtg ctcacccacc tgcgggagaa ggagatcctg
     2641 gacagctcgc tgcccagcag catcatcatt gggcctttct acatcaacac cgacaatgtc
     2701 aagcagagcc tgtccaagaa acgcaaggcc ctggccactt ccgtgctgga catccttgcc
     2761 aagaacctgc ataaggaggt ggatagcatc tgcgaggagt tccgcagcat cagccgcaag
     2821 atctatgaga agcccaacag cattgaggag ctggctgagc tgcgagagtg gatgaagggc
     2881 atcccggaga ggctggtggg cctggaggag cggattgtga aggtcatgga tgactaccag
     2941 gtcatggatg aattcctcta caacctcagc tcagatgact tcaatgacaa atggattgcc
     3001 agcaactggc cttctaagat ccttgggcag atagagctgg tgcagcagca gcatgtggag
     3061 gatgaggaga agttccgcaa aatccagatc atggatcaga acaacttcca agagaagctg
     3121 gaagggctgc agctggtagt agctggcttc tccatccatg tggagatttc acgtgcacac
     3181 gagatcgcca acgaggtgcg gcgtgtcaag aagcagctga aggactgcca gcagctggcc
     3241 atgctctaca acaaccgcga gcgcatcttc agcttgccca tcaccaatta tgacaagctc
     3301 tccaggatgg tgaaggagtt ccaaccctac ctggaccttt ggaccacagc gtctgactgg
     3361 ctgcgctggt cggagagctg gatgaatgac cccctctctg ccatcgatgc tgagcagctg
     3421 gagaagaacg tggttgaagc cttcaagacc atgcacaagt gcgtgaagca gtttaaggac
     3481 atgccagcct gccaggaagt ggccttggac atccgggccc gcatcgagga gttcaaacca
     3541 tacatcccac tgatccaggg gctgcgcaac cctggcatgc ggatccggca ctgggagaca
     3601 ctgtccaacc agatcaacat caatgtcagg cccaaggcca acctgacctt tgctcgctgc
     3661 ctggagatga acctgcagga ccatatcgag agcatcagca aggtggctga ggtggctggc
     3721 aaggagtacg ccatcgagca ggcactggac aagatggaga aggagtggtc gaccatcctg
     3781 ttcaatgtac tgccctacaa ggcgacagac acctacatcc tgaagagccc ggacgaggcc
     3841 tcacagctgc tggacgacca catcgtcatg acccagaata tgtcattttc accctacaag
     3901 aagccctttg agcagcgcat caactcctgg gagaacaaac tgaagctgac ccaggaggtt
     3961 ctggaggagt ggctgaactg tcagcggtcc tggctctacc tggagcccat ctttagctct
     4021 gaggacatca accagcagct gcctgtggag agcaagcgct accagaccat ggagcggatc
     4081 tggaagaaga tcatgaagaa tgcctacgag aaccgggagg tgatcaatgt gtgttccgac
     4141 ctgagaatgc tggacagcct gcgggactgc aacaagattc tggacctggt gcagaagggc
     4201 ctcagcgagt atctggagac caagaggagc gccttcccca gattctactt cctgtcagat
     4261 gatgaactac tagagatctt gtcgcagaca aaggacccca cggccgtgca gccacacctg
     4321 cgcaagtgct tcgagaacat cgctcggctg ctattccagg aggacctgga gatcacgcac
     4381 atgtactcag ccgaggggga ggaggtacag ttgtgcttct ccatctaccc ctccagcaac
     4441 gtggaggact ggctgcggga ggtggagcgc agcatgaagg ccagtgtgca cgacatcatt
     4501 gagaaggcca tcagggccta ccccacgatg cccaggaccc agtgggttct gaactggcct
     4561 ggccaggtga ccatcgctgg gtgccagacc tactggacca tggaggtggc agaggctctg
     4621 gaggccggca acctcagaag ccaactgttc ccccagctct gccagcagct cagtgatctg
     4681 gtggcccttg tgcgggggaa gctgtcccgc atgcagcggg cagtgctgtc agcgctaatc
     4741 gtcattgagg tccatgccaa ggacgtggtg agcaagctaa tccaggagaa cgtggtcagc
     4801 gtgaatgact tccagtggat ctcacagctg aggtactact ggacaaataa tgacctgtat
     4861 atccgtgctg tgaatgctga gttcatctat ggctatgagt acctgggcaa cagtgggagg
     4921 ctggtgatca cgcccctcac cgacaggtgc tacctgacac tgaccggagc tctgcacctc
     4981 aagtttgggg gtgccccagc tggcccagct ggcacaggca aaactgagac caccaaagac
     5041 ctgggtaagg ccttggccat acagaccgtt gtgttcaact gctctgacca gctcgacttc
     5101 atggccatgg gcaagttctt caagggcctg gccagtgctg gggcctgggc ctgcttcgac
     5161 gagttcaatc gcatcgacat cgaggtgctg tctgtggtgg cgcagcagat caccaccatc
     5221 cagaaggcgc agcagcagcg ggtggaacgc ttcatgtttg agggtgtgga gatcccactg
     5281 gtgccatcct gcgcagtgtt tatcaccatg aacccgggct acgctggccg cacggagctg
     5341 cctgacaatc tgaaggcgct cttccgaccc gtggccatga tggttccaga ttacgccatg
     5401 atcactgaga tctccctcta ttcctttggc tttaatgagg ccagtgtgct ggctaagaag
     5461 atcacaacca ccttcaagct gtcttctgag cagctcagct cccaggatca ctatgacttc
     5521 gggatgagag ccgtgaaaac tgtgatctcg gctgctggga acctcaagcg agaaaacccc
     5581 agcatgaatg aggagctgat ctgcctccgg gccatccgtg atgtgaacgt gcccaagttc
     5641 ctgcaggagg acctcaagct cttctctggc atcgtgtccg acctgtttcc caccatcaag
     5701 gaggaggaca cggactacgg catcctggat gaggccatcc gcgaggcctg caggaacagc
     5761 aacctcaagg atgtggaggg cttcctgaca aagtgcatcc agctctacga gaccacggtg
     5821 gtacgacacg gcctcatgct cgtcgggccc acaggctccg gcaagagtac ttgttacaga
     5881 gtcctggcag ctgccatgac gtcactgaaa gggcagccat ccatcagtgg tggcatgtac
     5941 gaggctgtca actactacgt gctcaacccc aagtccatca cgatgggcca gctgtacggg
     6001 gagtttgacc tcctcaccca tgagtggaca gacgggatat tctcctcgtt catccgggcg
     6061 ggggccatca cctccgacac caacaagaag tggtacatgt tcgatgggcc ggtggatgcc
     6121 atctggattg agaacatgaa cacggtgctg gatgacaaca agaagctgtg cctcagctct
     6181 ggggagatca tcaagctcac agaggcaatg accatgatgt tcgaggtgca agacctggcg
     6241 gtggcttcac cagctacagt ctcccgctgt ggcatggtgt acctggagcc cagcatcctg
     6301 gggctcatgc ccttcatcga gtgctggctg aggaagctgc ctcccttgct gaagccctat
     6361 gaggagcatt tcaaggccct ctttgtcagc ttcctggagg aatccatctc cttcgttcgg
     6421 tcctcagtga aggaggtgat cgcctcaacc aactgcaacc tgaccatgag cctcctcaag
     6481 ctgctggact gcttcttcaa gccctttctg cctagagagg gcctcaagaa aataccctct
     6541 gaaaagctga gtcgcatcgt agagttgatc gagccctggt tcatcttctc cctgatctgg
     6601 agcgtgggtg ccactgggga cagcagtggc cgcaccagtt tcagccactg gctaaggctc
     6661 aagatggaga acgaacagct gactctgctt ttcccagaag aggggctggt gttcgattac
     6721 aggctggagg acgcgggcat cagtggcacc aacgacagtg aggatgaaga ggaggaatac
     6781 aagcaggttg cctgggtgaa gtggatggac tcctcagctc cattcaccat ggtaccagac
     6841 accaactact gcaacatcat tgtgcccacc atggacaccg tgcagatgtc ccatttactg
     6901 gacatgctgc tcaccaacaa gaagcccgtg ctgtgcattg ggccaacagg cacggggaag
     6961 acgctcacca tctctgacaa gctcctcaag aacctggcac tggattacat cagccacttc
     7021 ctcaccttct cagcccgcac ttcagccaac cagacccagg acttcattga cagcaagctg
     7081 gacaagaggc ggaagggtgt gtttggacca cctctggggc gcaactttat cttcttcatc
     7141 gatgacctga acatgccggc cctggagacc tacggtgcac agccacccat cgagctgttg
     7201 cgccagtgga tggaccacgg cggctggtac gaccgcaaga tcattggtgc cttcaagaac
     7261 ctagtggaca tcaactttgt ctgtgccatg ggccccccgg gtggaggcag gaacaccgtc
     7321 accccgcggc tgatgcgtca cttcaactac ctgtctttcg ctgagatgga cgaggtcagc
     7381 aagaaacgca tcttctccac catcctgggc aactggttgg atggactcct tggagaaaaa
     7441 agctaccggg agcgtgtgcc tggggccccc cacattgccc acttcacgga gccccttgtg
     7501 gaagccacca tcatggtgta tgcaaccatc acctcccagc tgctgcccac tccagccaag
     7561 tcccactaca ccttcaacct gagggacctc tccaaggtct tccaaggcat gctcatggct
     7621 gacccggcca aggtcgagga ccaagtgcag ctgctgcgac tgtggtatca cgagaactgc
     7681 cgcgtgttcc gggaccgact ggtgaatgag gaggaccgca gctggttcga ccagctcctc
     7741 aagcgctgca tggagcagtg ggaggtgacc ttcaacaagg tctgcccctt ccagcccatt
     7801 ctttacgggg acttcatgtc accaggctcc gatgtcaagt cctacgagct catcaccagt
     7861 gagagtaaga tgatgcaggt gatagaggag tacatagagg actacaacca gatcaacacg
     7921 gccaagctga agctggtcct cttcatggac gccatgagcc acatctgtcg catcagccgc
     7981 accctacgcc aggcgctggg caatgcactc ctgctgggcg tgggtggcag cggccgcagc
     8041 tccctcacaa ggctcgcctc gcacatggcc gagtacgagt gcttccagat tgaactatcc
     8101 aagaactacg gcatgtccga gtggcgagat gatgtgaaga aggtcctgct caaggcgggc
     8161 ctacagaacc tacccatcac cttcctcttc tcagacaccc agatcaagaa cgaatccttc
     8221 ctggaagata tcaacaacgt cctaaactct ggtgacattc ccaatctgta tactgcggac
     8281 gagcaggacc agatcgtcag caccatgcgg ccctatatcc aggagcaggg cctacagccc
     8341 accaaggcca acctcatggc tgcttacaca gggcgtgtgc gcagcaacat ccacatggtg
     8401 ctgtgcatga gccccatcgg agaggtcttc cgagctcgtc tgaggcagtt tccctccctg
     8461 gtcaactgct gtaccatcga ctggtttaac gagtggccgg cagaagccct gaagtctgtg
     8521 gccaccgtgt tcctcaatga gatcccagaa ctggaatcct cccaggaaga aatccaagga
     8581 ctgatccagg tctgtgtgta catccaccag tcggtgtcca agaagtgcat cgagtacctg
     8641 gcagagctga cccgccacaa ctatgtgacc cccaagagct acttggagct gcttcatatt
     8701 ttctccatcc tcatcgggca gaagaaactg gagctgaaaa ctgccaagaa ccgcatgaag
     8761 agcggcctcg acaagctgct gcgcacttct gaggatgtag ccaagatgca ggaggacctg
     8821 gagagtatgc accccctgct ggaggaggct gccaaggaca ccatgctcac catggagcag
     8881 atcaaggtgg atacggccat cgccgaggag acccggaatt cagtgcagac agaggagatc
     8941 aaagccaatg agaaggccaa gaaggcacaa gctattgctg acgatgccca gaaggacctg
     9001 gacgaggcgt tgccagccct ggatgcggct ctggccagcc tgcgcaacct caacaagaac
     9061 gatgtgaccg aggtacgtgc catgcagcgg ccacccccgg gtgtgaaact ggtcatagaa
     9121 gctgtgtgca ttatgaaagg catcaagccc aagaaggtgc ctggagaaaa gccaggcacc
     9181 aaggtggatg actactggga gcctggcaag gggctgctgc aggacccggg ccacttcctt
     9241 gagagcctct tcaagtttga caaggacaac attggggatg tggtgatcaa agccatccag
     9301 ccgtacatcg ataatgaaga gttccagcca gccaccattg ccaaggtgtc caaggcttgc
     9361 acctccatct gccagtgggt gcgcgccatg cacaagtacc actttgtggc caaggccgtg
     9421 gagcccaagc ggcaagccct gctggaggcc caggatgacc tgggggtgac acagaggatc
     9481 ctggatgagg caaaacagcg ccttcgtgag gtggaggacg gcatcgccac aatgcaggct
     9541 aagtaccggg aatgcattac caagaaggag gagctggagc tgaagtgtga gcagtgtgag
     9601 cagcggctgg gccgagctgg caagctcatc aacgggctgt cggatgagaa ggtgcgctgg
     9661 caggagacgg tggagaacct gcagtacatg ctcaacaaca tctccggcga tgtcctggtg
     9721 gccgctggct ttgtggccta cctgggcccc ttcacgggcc agtaccgcac ggtgctctac
     9781 gacagctggg tcaagcagct caggagccac aatgtcccac acacctccga gcccacgcta
     9841 atcgggacgc tggggaaccc tgtgaagatc cgatcgtggc agatcgctgg cctccccaac
     9901 gacacactgt cagtggagaa cggggtcatc aaccagtttt cccagcgctg gacccacttc
     9961 attgaccctc agagccaggc caacaaatgg atcaagaaca tggagaagga caatgggctg
    10021 gatgtgttca agttgagtga ccgcgacttc ctgcgcagca tggagaacgc catccgcttt
    10081 ggcaagccat gtctcctgga gaacgtgggc gaggagctag acccagccct ggagccagtg
    10141 ctgctcaagc agacgtacaa gcagcaggga aacacggtgc tgaagctggg ggacacggtg
    10201 atcccctacc atgaggactt caggatgtac atcaccacca agctgcccaa cccacactac
    10261 acgcccgaga tctccaccaa actcaccctc atcaacttca ccctgtcgcc cagtggccta
    10321 gaggaccagc tactgggcca ggtagtggca gaggagcgac ccgacctgga ggaggccaag
    10381 aaccagctga ttatcagtaa tgccaagatg cgccaggagc tgaaggacat tgaggaccag
    10441 atcctgtacc ggctcagctc ctccgagggc aaccctgtag atgacatgga actcatcaag
    10501 gtgctggaag cctccaagat gaaggctgct gagatccagg ccaaagtcag gattgcagag
    10561 cagacggaga aggacatcga cctgacgcgc atggagtaca tacccgtggc catccgcacc
    10621 cagatcctct tcttctgtgt gtccgacctg gccaacgtgg accccatgta ccagtactcc
    10681 cttgagtggt ttctcaacat cttcctctcg ggcatcgcca actcagagag agcagacaac
    10741 ctgaagaagc gcatctccaa catcaaccgc tacctgacct acagcctcta cagcaacgtc
    10801 tgccgcagcc tctttgagaa gcacaagctg atgtttgcct tcctgctgtg tgttcgcatc
    10861 atgatgaacg agggcaaaat caaccagagt gagtggcgat acctcctgtc tgggggctcc
    10921 atctcgatca tgactgagaa tccggcaccg gactggctgt cagaccgggc ttggcgagac
    10981 atcctagcac tctcgaacct gccaaccttt tcctccttct cttccgactt cgtgaagcac
    11041 ctctcagaat tccgggtcat cttcgacagc cttgagcccc accgggagcc tttgcctggc
    11101 atctgggacc agtacctaga ccagttccag aagctgctag tcctccgctg cctgcgtggg
    11161 gacaaggtta ccaacgccat gcaggacttt gtggccacca acctggagcc acgcttcatt
    11221 gaaccccaga cagccaatct gtcagtggtg ttcaaagact ccaactccac cacacccctc
    11281 atctttgtgc tgtcacccgg cacagaccct gctgccgacc tctacaagtt tgccgaagaa
    11341 atgaagttct ccaaaaagct ctctgccatc tccctgggcc aggggcaggg ccctcgggca
    11401 gaagccatga tgcgcagctc catagagagg ggcaaatggg tcttcttcca gaactgccac
    11461 ctggcaccaa gctggatgcc agccctagaa cgcctcatcg agcacatcaa ccccgacaag
    11521 gtacacaggg acttccgcct ctggctcacc agcctgccca gcaacaagtt cccagtgtcc
    11581 atcctgcaga acggctccaa gatgaccatt gagccgccac gcggtgtcag ggccaacctg
    11641 ctgaagtcct atagtagcct tggtgaagac ttcctcaact cctgccacaa ggtgatggag
    11701 ttcaagtctc tgctgctgtc tctgtgcttg ttccatggga acgccctgga gcgccgtaag
    11761 tttgggcccc tgggcttcaa catcccctat gagttcacgg atggagatct gcgcatctgc
    11821 atcagccagc tcaagatgtt cctggacgaa tatgatgaca tcccctacaa ggtcctcaag
    11881 tacacggcag gggagatcaa ttacgggggc cgtgtcactg atgactggga ccggcgctgc
    11941 atcatgaaca tcttggagga cttctacaac cctgacgtgc tctcccctga gcacagctac
    12001 agcgcctcgg gcatctacca ccagatcccg cctacctacg acctccacgg ctacctctcc
    12061 tacatcaaga gcctcccact caatgatatg cctgagatct ttggcctgca tgacaatgcc
    12121 aacatcacct ttgcccagaa cgagacgttc gccctcctgg gcaccatcat ccagctgcaa
    12181 cccaaatcat cttctgcagg cagccagggc cgggaggaga tagtggagga cgtcacccaa
    12241 aacattctgc tcaaggtgcc tgagcctatc aacttgcaat gggtgatggc caagtaccca
    12301 gtgctgtatg aggaatcaat gaacacagta ctagtacaag aggtcattag gtacaatcgg
    12361 ctgctgcagg tgatcacaca gacactgcaa gacctactca aggcactcaa ggggctggta
    12421 gtgatgtcct ctcagctgga gctgatggct gccagcctgt acaacaatac tgtgcctgag
    12481 ctctggagtg ccaaggccta cccatcgctc aagcctctgt catcatgggt catggacctg
    12541 ctgcaacgcc tggactttct gcaggcctgg atccaagatg gcatcccagc tgtcttctgg
    12601 atcagtggat tcttcttccc ccaggctttc ttaacaggca ctctgcagaa ttttgcccgc
    12661 aaatttgtca tctccattga caccatctcc tttgatttca aggtgatgtt tgaggcacca
    12721 tcagagttaa cacaaagacc ccaagtaggg tgctatatcc atggattatt cctggaaggt
    12781 gcccgctggg atccagaggc cttccagctg gctgagtctc agcccaagga gctgtacaca
    12841 gagatggccg ttatctggct cttgccaaca cccaaccgca aggcccagga ccaggacttt
    12901 tacctgtgcc ccatctacaa gacactgact cgtgctggaa cactatcaac cacaggacac
    12961 tctaccaact atgtcattgc tgtggagatc cccacccatc agccccagcg acactggata
    13021 aagcgtggtg tggccctcat ctgtgccctg gactactaga ctcagacaga agggctgggg
    13081 ccattaaagc tgaattttct aagca
//
