LOCUS       NM_001377530            7984 bp    mRNA    linear   PRI 20-OCT-2024
DEFINITION  Homo sapiens deleted in malignant brain tumors 1 (DMBT1),
            transcript variant 5, mRNA.
ACCESSION   NM_001377530 XM_011539388
VERSION     NM_001377530.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7984)
  AUTHORS   Gursoy,U.K., Gursoy,M., Loimaranta,V. and Rautava,J.
  TITLE     Salivary Th17 cytokine, human beta-defensin 1-3, and salivary
            scavenger and agglutinin levels in Crohn's disease
  JOURNAL   Clin Oral Investig 28 (1), 108 (2024)
   PUBMED   38246944
  REMARK    GeneRIF: Salivary Th17 cytokine, human beta-defensin 1-3, and
            salivary scavenger and agglutinin levels in Crohn's disease.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7984)
  AUTHORS   Koopaie,M., Ghafourian,M., Manifar,S., Younespour,S., Davoudi,M.,
            Kolahdooz,S. and Shirkhoda,M.
  TITLE     Evaluation of CSTB and DMBT1 expression in saliva of gastric cancer
            patients and controls
  JOURNAL   BMC Cancer 22 (1), 473 (2022)
   PUBMED   35488257
  REMARK    GeneRIF: Evaluation of CSTB and DMBT1 expression in saliva of
            gastric cancer patients and controls.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 7984)
  AUTHORS   Wang,L., Tuo,H., Song,Z., Li,W. and Peng,Y.
  TITLE     Reg3A (regenerating family member 3 alpha) acts as a tumor
            suppressor by targeting DMBT1 (deleted in malignant brain tumors 1)
            in gastric cancer
  JOURNAL   Bioengineered 12 (1), 7644-7655 (2021)
   PUBMED   34605357
  REMARK    GeneRIF: Reg3A (regenerating family member 3 alpha) acts as a tumor
            suppressor by targeting DMBT1 (deleted in malignant brain tumors 1)
            in gastric cancer.
REFERENCE   4  (bases 1 to 7984)
  AUTHORS   Hains,D.S., Polley,S., Liang,D., Saxena,V., Arregui,S., Ketz,J.,
            Barr-Beare,E., Rawson,A., Spencer,J.D., Cohen,A., Hansen,P.L.,
            Tuttolomondo,M., Casella,C., Ditzel,H.J., Cohen,D., Hollox,E.J. and
            Schwaderer,A.L.
  TITLE     Deleted in malignant brain tumor 1 genetic variation confers
            urinary tract infection risk in children and mice
  JOURNAL   Clin Transl Med 11 (7), e477 (2021)
   PUBMED   34323417
  REMARK    GeneRIF: Deleted in malignant brain tumor 1 genetic variation
            confers urinary tract infection risk in children and mice.
REFERENCE   5  (bases 1 to 7984)
  AUTHORS   Zarei,M., Bose,D., Ali Akbari Ghavimi,S., Nouri-Vaskeh,M.,
            Mohammadi,M. and Sahebkar,A.
  TITLE     Potential role of glycoprotein 340 in milder SARS-CoV-2 infection
            in children
  JOURNAL   Expert Rev Anti Infect Ther 19 (6), 675-677 (2021)
   PUBMED   33444084
  REMARK    GeneRIF: Potential role of glycoprotein 340 in milder SARS-CoV-2
            infection in children.
REFERENCE   6  (bases 1 to 7984)
  AUTHORS   Tino,M.J. and Wright,J.R.
  TITLE     Glycoprotein-340 binds surfactant protein-A (SP-A) and stimulates
            alveolar macrophage migration in an SP-A-independent manner
  JOURNAL   Am J Respir Cell Mol Biol 20 (4), 759-768 (1999)
   PUBMED   10101009
REFERENCE   7  (bases 1 to 7984)
  AUTHORS   Mori,M., Shiraishi,T., Tanaka,S., Yamagata,M., Mafune,K.,
            Tanaka,Y., Ueo,H., Barnard,G.F. and Sugimachi,K.
  TITLE     Lack of DMBT1 expression in oesophageal, gastric and colon cancers
  JOURNAL   Br J Cancer 79 (2), 211-213 (1999)
   PUBMED   9888459
REFERENCE   8  (bases 1 to 7984)
  AUTHORS   Mollenhauer,J., Wiemann,S., Scheurlen,W., Korn,B., Hayashi,Y.,
            Wilgenbus,K.K., von Deimling,A. and Poustka,A.
  TITLE     DMBT1, a new member of the SRCR superfamily, on chromosome
            10q25.3-26.1 is deleted in malignant brain tumours
  JOURNAL   Nat Genet 17 (1), 32-39 (1997)
   PUBMED   9288095
REFERENCE   9  (bases 1 to 7984)
  AUTHORS   Holmskov,U., Lawson,P., Teisner,B., Tornoe,I., Willis,A.C.,
            Morgan,C., Koch,C. and Reid,K.B.
  TITLE     Isolation and characterization of a new member of the scavenger
            receptor superfamily, glycoprotein-340 (gp-340), as a lung
            surfactant protein-D binding molecule
  JOURNAL   J Biol Chem 272 (21), 13743-13749 (1997)
   PUBMED   9153228
REFERENCE   10 (bases 1 to 7984)
  AUTHORS   Rasheed,B.K., McLendon,R.E., Friedman,H.S., Friedman,A.H.,
            Fuchs,H.E., Bigner,D.D. and Bigner,S.H.
  TITLE     Chromosome 10 deletion mapping in human gliomas: a common deletion
            region in 10q25
  JOURNAL   Oncogene 10 (11), 2243-2246 (1995)
   PUBMED   7784070
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL603764.27.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Jan 21, 2020 this sequence version replaced XM_011539388.3.
            
            Summary: Loss of sequences from human chromosome 10q has been
            associated with the progression of human cancers. This gene was
            originally isolated based on its deletion in a medulloblastoma cell
            line. This gene is expressed with transcripts of 6.0, 7.5, and 8.0
            kb in fetal lung and with one transcript of 8.0 kb in adult lung,
            although the 7.5 kb transcript has not been characterized. The
            encoded protein precursor is a glycoprotein containing multiple
            scavenger receptor cysteine-rich (SRCR) domains separated by
            SRCR-interspersed domains (SID). Transcript variant 2 (8.0 kb) has
            been shown to bind surfactant protein D independently of
            carbohydrate recognition. This indicates that DMBT1 may not be a
            classical tumor suppressor gene, but rather play a role in the
            interaction of tumor cells and the immune system. [provided by
            RefSeq, Mar 2016].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA1968540,
                              SAMEA1968832 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000338354.10/ ENSP00000342210.4
            RefSeq Select criteria    :: based on manual assertion,
                                         conservation, expression, longest
                                         protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-78                AL603764.27        57196-57273
            79-108              AL603764.27        62409-62438
            109-156             AL603764.27        66604-66651
            157-204             AL603764.27        67332-67379
            205-252             AL603764.27        68756-68803
            253-300             AL603764.27        70157-70204
            301-624             AL603764.27        72841-73164
            625-654             AL603764.27        74253-74282
            655-696             AL603764.27        75160-75201
            697-1020            AL603764.27        76020-76343
            1021-1050           AL603764.27        77308-77337
            1051-1083           AL603764.27        78235-78267
            1084-1407           AL603764.27        79042-79365
            1408-1437           AL603764.27        80764-80793
            1438-1476           AL603764.27        81713-81751
            1477-1800           AL603764.27        82502-82825
            1801-2124           AL603764.27        85386-85709
            2125-2154           AL603764.27        87107-87136
            2155-2193           AL603764.27        87921-87959
            2194-2517           AL603764.27        88714-89037
            2518-2547           AL603764.27        90011-90040
            2548-2580           AL603764.27        90938-90970
            2581-2904           AL603764.27        91745-92068
            2905-2934           AL603764.27        93467-93496
            2935-2973           AL603764.27        94416-94454
            2974-3297           AL603764.27        95216-95539
            3298-3327           AL603764.27        96506-96535
            3328-3360           AL603764.27        97433-97465
            3361-3684           AL603764.27        98239-98562
            3685-3714           AL603764.27        99542-99571
            3715-3747           AL603764.27        101492-101524
            3748-4071           AL603764.27        102298-102621
            4072-4101           AL603764.27        103601-103630
            4102-4134           AL603764.27        105551-105583
            4135-4458           AL603764.27        106357-106680
            4459-4488           AL603764.27        107660-107689
            4489-4521           AL603764.27        109610-109642
            4522-4845           AL603764.27        110416-110739
            4846-4875           AL603764.27        111719-111748
            4876-4908           AL603764.27        113670-113702
            4909-5232           AL603764.27        114459-114782
            5233-5262           AL603764.27        115750-115779
            5263-5301           AL603764.27        116695-116733
            5302-5625           AL603764.27        117499-117822
            5626-5652           AL603764.27        121719-121745
            5653-5685           AL603764.27        122375-122407
            5686-5839           AL603764.27        126282-126435
            5840-6042           AL603764.27        126730-126932
            6043-6363           AL603764.27        127403-127723
            6364-6384           AL603764.27        128297-128317
            6385-6414           AL603764.27        129303-129332
            6415-6565           AL603764.27        129633-129783
            6566-6774           AL603764.27        132433-132641
            6775-6959           AL603764.27        133570-133754
            6960-7369           AL603764.27        136482-136891
            7370-7984           AL603764.27        139564-140178
FEATURES             Location/Qualifiers
     source          1..7984
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="10"
                     /map="10q26.13"
     gene            1..7984
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /note="deleted in malignant brain tumors 1"
                     /db_xref="GeneID:1755"
                     /db_xref="HGNC:HGNC:2926"
                     /db_xref="MIM:601969"
     exon            1..78
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     CDS             18..7646
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /note="isoform e precursor is encoded by transcript
                     variant 5; hensin; glycoprotein 340; salivary agglutinin;
                     surfactant pulmonary-associated D-binding protein;
                     vomeroglandin; salivary scavenger and agglutinin;
                     scavenger receptor cysteine-rich domain-containing protein
                     DMBT1"
                     /codon_start=1
                     /product="scavenger receptor cysteine-rich
                     domain-containing protein DMBT1 isoform e precursor"
                     /protein_id="NP_001364459.1"
                     /db_xref="CCDS:CCDS91368.1"
                     /db_xref="GeneID:1755"
                     /db_xref="HGNC:HGNC:2926"
                     /db_xref="MIM:601969"
                     /translation="MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDPTV
                     AEGSPFPSESTLESTVAEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLAL
                     RLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQG
                     SGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVR
                     ISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLG
                     CGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICS
                     APQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSW
                     DTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSH
                     NCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVE
                     VLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGN
                     ESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSLALRLVNGGDRCQGRVEVLYRGSWG
                     TVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCP
                     NNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITLPPSTVGSESSLTLRLVNGSD
                     RCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLD
                     DVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPTPSPDTWPTSHASTAGP
                     ESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGN
                     ARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSP
                     DTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVV
                     CRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDA
                     GVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTV
                     CDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHN
                     GWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQG
                     RVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC
                     SGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSL
                     ALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFG
                     QGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWP
                     TSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGC
                     GWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSA
                     SQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWD
                     TNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHN
                     CGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEV
                     LYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNE
                     SYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARPSSNCGGFLF
                     YASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDG
                     SLNSSLLLGKICNDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLRLVN
                     LNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGS
                     GPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPN
                     TDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGCNY
                     DYIEVFDGPYRSSPLIARVCDGARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPS
                     NDSTNLLCLPNHMQASVSRSYLQSLGFSASDLVISTWNGYYECRPQITPNLVIFTIPY
                     SGCGTFKQADNDTIDYSNFLTAAVSGGIIKRRTDLRIHVSCRMLQNTWVDTMYIANDT
                     IHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVDLNQDLYVQAEILHSDA
                     VLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSLRIARFRFRAFHFLN
                     RFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVLGPIQLQTPPRRE
                     EEPR"
     exon            79..108
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            109..156
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            157..204
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            205..252
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            253..300
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            301..624
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            625..654
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            655..696
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            697..1020
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            1021..1050
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            1051..1083
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            1084..1407
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            1408..1437
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            1438..1476
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            1477..1800
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            1801..2124
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            2125..2154
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            2155..2193
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            2194..2517
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            2518..2547
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            2548..2580
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            2581..2904
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            2905..2934
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            2935..2973
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            2974..3297
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            3298..3327
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            3328..3360
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            3361..3684
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            3685..3714
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            3715..3747
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            3748..4071
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            4072..4101
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            4102..4134
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            4135..4458
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            4459..4488
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            4489..4521
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            4522..4845
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            4846..4875
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            4876..4908
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            4909..5232
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            5233..5262
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            5263..5301
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            5302..5625
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            5626..5652
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            5653..5685
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            5686..5839
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            5840..6042
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            6043..6363
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            6364..6384
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            6385..6414
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            6415..6565
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            6566..6774
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            6775..6959
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            6960..7369
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     exon            7370..7984
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7960..7965
                     /regulatory_class="polyA_signal_sequence"
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /note="hexamer: CATAAA"
     polyA_site      7984
                     /gene="DMBT1"
                     /gene_synonym="GP340; muclin; SAG; SALSA"
                     /note="major polyA site"
ORIGIN      
        1 gagaagaacc cagcaaaatg gggatctcca cagtcatcct tgaaatgtgt cttttatggg
       61 gacaagttct atctacaggt gggtggatcc caaggactac agactacgct tcactgattc
      121 cctcggaggt gcccttggat ccaactgtag cagaaggttc tccatttccc tcggagtcga
      181 ccctggagtc aactgtagca gaaggttctc cgatttcctt ggagtcaacc ctggagtcaa
      241 ccgtagcaga aggttctctg attccctcag agtcaaccct ggagtcaact gtagcagaag
      301 gatctgattc tggtttggcc ctgaggctgg tgaatggaga tggcaggtgt cagggccgag
      361 tggagatcct ataccgaggc tcctggggca ccgtgtgtga tgacagctgg gacaccaatg
      421 atgccaacgt ggtctgtagg cagctgggtt gtggctgggc catgtcagct ccaggaaatg
      481 cctggtttgg ccagggctca ggacccattg ccctggatga tgtgcgctgc tcaggacacg
      541 aatcctacct gtggagctgc ccccacaatg gctggctctc ccataactgt ggccatggtg
      601 aagatgctgg tgttatctgc tcagctgccc agcctcagtc aacactcagg ccagaaagtt
      661 ggcctgtcag gatatcacca cctgtaccca cagaaggatc tgaatccagt ttggccctga
      721 ggctggtgaa tggaggcgac aggtgtcgag gccgagtgga ggtcctatac cgaggctcct
      781 ggggcaccgt gtgtgatgac tactgggaca ccaatgatgc caatgtggtc tgcaggcagc
      841 tgggctgtgg ctgggccatg tcagccccag gaaatgccca gtttggccag ggctcaggac
      901 ccattgtcct ggatgatgtg cgctgctcag gacatgagtc ctacctgtgg agctgccccc
      961 acaatggctg gctcacccac aactgtggcc atagtgaaga cgctggtgtc atctgctcag
     1021 ctccccagtc ccggccgaca cccagcccag atacttggcc gacctcacat gcatcaacag
     1081 caggacctga atccagtttg gccctgaggc tggtgaatgg aggtgacagg tgtcagggcc
     1141 gagtggaggt cctataccga ggctcctggg gcaccgtgtg tgatgatagc tgggacacca
     1201 gtgacgccaa tgtggtctgc cggcagctgg gctgtggctg ggccacgtca gccccaggaa
     1261 atgcccggtt tggccagggt tcaggaccca ttgtcctgga tgacgtgcgc tgctcaggct
     1321 atgagtccta cctgtggagc tgcccccaca atggctggct ctcccataac tgtcagcaca
     1381 gtgaagacgc tggtgtcatc tgctcagctg cccactcctg gtcgacgccc agtccagaca
     1441 cgttgccgac catcacctta cctgcatcga cagtaggatc tgaatccagt ttggccctga
     1501 ggctggtgaa tggaggtgac aggtgtcagg gccgagtgga ggtcctatac cgaggctcct
     1561 ggggcaccgt gtgtgatgac agctgggaca ccaatgatgc caatgtggtc tgcaggcagc
     1621 tgggctgtgg ctgggccatg ttggccccag gaaatgcccg gtttggtcag ggctcaggac
     1681 ccattgtcct ggatgacgtg cgctgctcag ggaatgagtc ctacttgtgg agctgccccc
     1741 acaatggctg gctctcccat aactgtggcc atagtgaaga cgctggtgtc atctgctcag
     1801 gacctgaatc cagtttggcc ctgaggctgg tgaatggagg tgacaggtgt cagggccgag
     1861 tggaggtcct ataccgaggc tcttggggca ccgtgtgtga tgacagctgg gacaccaatg
     1921 atgccaatgt ggtctgcagg cagctgggct gtggctgggc cacgtcagcc ccaggaaatg
     1981 cccggtttgg tcagggctca ggacccattg tcctggatga tgtgcgctgc tcaggacatg
     2041 agtcctacct gtggagctgc cccaacaatg gctggctctc ccacaactgt ggccatcatg
     2101 aagatgctgg tgtcatctgc tcagctgccc agtcccggtc gacgcccagg ccagacacgt
     2161 tgtcgaccat cacgttacct ccatcgacag taggatctga atccagtttg accctgaggc
     2221 tggtgaatgg aagtgacagg tgtcagggcc gagtagaggt cctataccga ggctcctggg
     2281 gcaccgtgtg tgatgacagc tgggatacca atgatgccaa tgtggtctgc aggcagctgg
     2341 gctgtggctg ggccacgtcg gccccaggaa atgcccggtt tggccagggc tcaggaccca
     2401 ttgttctgga tgatgtgcgc tgctcaggac acgagtccta cctgtggagc tgcccccaca
     2461 atggctggct ctcccacaac tgtggccatc atgaagatgc tggtgtcatc tgctcagttt
     2521 cccagtcccg gccgacaccc agtccagata cttggccgac ctcacatgca tcaacagcag
     2581 gacctgaatc cagtttggcc ctgaggctgg tgaatggagg tgacaggtgt cagggccgag
     2641 tggaggtcct ataccgaggc tcctggggca ccgtgtgtga tgatagctgg gacaccagtg
     2701 acgccaatgt ggtctgccgg cagctgggct gtggctgggc cacgtcagcc ccaggaaatg
     2761 cccggtttgg ccagggttca ggacccattg tcctggatga cgtgcgctgc tcaggctatg
     2821 agtcctacct gtggagctgc ccccacaatg gctggctctc ccataactgt cagcacagtg
     2881 aagacgctgg tgtcatctgc tcagctgccc actcctggtc gacgcccagt ccagacacat
     2941 tgccgaccat caccttgcct gcatcgacag taggatctga atccagtttg gccctgaggc
     3001 tggtgaatgg aggtgacagg tgtcagggcc gagtggaggt cctataccaa ggctcctggg
     3061 gcaccgtgtg cgatgacagc tgggacacca atgatgccaa tgtcgtctgc aggcaactgg
     3121 gctgtggctg ggccatgtca gccccaggaa atgcccggtt tggtcagggc tcaggaccca
     3181 ttgtcctgga tgatgtgcgc tgctcaggac acgagtctta cctgtggagc tgcccccaca
     3241 atggctggct ctcccacaac tgtggccata gtgaagacgc tggtgtcatc tgctcagctt
     3301 cccagtcccg gccaacacct agtccagaca cttggccaac ctcacatgca tcaacagcag
     3361 gatctgaatc cagtttggcc ctgaggctgg tgaatggagg tgacaggtgt cagggccgag
     3421 tggaggtcct ataccgaggc tcctggggca ccgtgtgtga tgactactgg gacaccaatg
     3481 atgccaatgt ggtttgcagg cagctgggct gtggctgggc catgtcagcc ccaggaaatg
     3541 cccggtttgg ccagggttca ggacccattg tcctggatga tgtgcgctgc tcaggacatg
     3601 agtcctatct gtggagctgc ccccacaatg gctggctctc ccacaactgt ggccatcatg
     3661 aagacgctgg tgtcatctgc tcagcttccc agtcccagcc gacacccagc ccagacactt
     3721 ggccaacctc acatgcatca acagcaggat ctgaatccag tttggccctg aggctggtga
     3781 atggaggtga caggtgtcag ggccgagtgg aggtcctata ccgaggctcc tggggcaccg
     3841 tgtgtgatga ctactgggac accaatgatg ccaatgtggt ttgcaggcag ctgggctgtg
     3901 gctgggccac gtcagcccca ggaaatgccc ggtttggcca gggttcagga cccattgtcc
     3961 tggatgatgt gcgctgctca ggacatgagt cctatctgtg gagctgcccc cacaatggct
     4021 ggctctccca caactgtggc catcatgaag acgctggtgt catctgctca gcttcccagt
     4081 cccagccgac acccagccca gacacttggc caacctcaca tgcatcaaca gcaggatctg
     4141 aatccagttt ggccctgagg ctggtgaatg gaggtgacag gtgtcagggc cgagtggagg
     4201 tcctataccg aggctcctgg ggcaccgtgt gtgatgacta ctgggacacc aatgatgcca
     4261 atgtggtttg caggcagctg ggctgtggct gggccacgtc agccccagga aatgcccggt
     4321 ttggccaggg ttcaggaccc attgtcctgg atgatgtgcg ctgctcagga catgagtcct
     4381 atctgtggag ctgcccccac aatggctggc tctcccacaa ctgtggccat catgaagacg
     4441 ctggtgtcat ctgctcagct tcccagtccc agccgacacc cagcccagac acttggccaa
     4501 cctcacatgc atcaacagca ggatctgaat ccagtttggc cctgaggctg gtgaatggag
     4561 gtgacaggtg tcagggccga gtggaggtcc tataccgagg ctcctggggc accgtgtgtg
     4621 atgactactg ggacaccaat gatgccaatg tggtttgcag gcagctgggc tgtggctggg
     4681 ccacgtcagc cccaggaaat gcccggtttg gccagggttc aggacccatt gtcctggatg
     4741 atgtgcgctg ctcaggacat gagtcctatc tgtggagctg cccccacaat ggctggctct
     4801 cccacaactg tggccatcat gaagacgctg gtgtcatctg ctcagcttcc cagtcccagc
     4861 cgacacccag cccagacact tggccaacct ctcgtgcatc aacagcagga tctgaatcca
     4921 ctttggccct gagactggtg aatggaggtg acaggtgtcg aggccgagtg gaggtcctat
     4981 accaaggctc ctggggcacc gtgtgtgatg actactggga caccaatgat gccaacgtgg
     5041 tctgcaggca gctgggctgt ggctgggcca tgtcagcccc aggaaatgcc cagtttggcc
     5101 agggctcagg acccattgtc ctggatgatg tgcgctgctc aggacacgag tcttacctgt
     5161 ggagctgccc ccacaatggc tggctctccc acaactgtgg ccatcatgaa gatgctggtg
     5221 tcatctgctc agctgctcag tcccagtcaa cgcccaggcc agatacttgg ctgaccacca
     5281 acttaccggc attgacagta ggatctgaat ccagtttggc tctgaggctg gtgaatggag
     5341 gtgacaggtg tcgaggccga gtggaggtcc tgtatcgagg ctcctgggga accgtgtgtg
     5401 atgacagctg ggacaccaat gatgccaatg tggtctgcag gcagctgggc tgtggctggg
     5461 ccatgtcggc cccaggaaat gcccggtttg gccagggctc aggacccatt gtcctggatg
     5521 atgtgcgctg ctcagggaat gagtcctacc tgtggagctg cccccacaaa ggctggctca
     5581 cccacaactg tggccatcac gaagacgctg gtgtcatctg ctcagccacc caaataaatt
     5641 ctactacgac agattggtgg catccaacaa ctacaaccac tgcaagaccc tcttcaaatt
     5701 gtggtggctt cttattctat gccagtggga cattctccag cccatcctac cctgcatact
     5761 accccaacaa tgctaagtgt gtttgggaaa tagaagtgaa ttctggttat cgcataaacc
     5821 tgggcttcag taatctgaaa ttggaggcac accataactg cagttttgat tatgttgaaa
     5881 tctttgatgg atcattgaat agcagtctcc tgctggggaa aatctgtaat gataccaggc
     5941 aaatatttac atcttcttac aaccgaatga ccattcactt tcgaagtgac atcagtttcc
     6001 aaaacactgg ctttttggct tggtataact ccttcccaag cgatgccacc ttgaggttgg
     6061 tcaatttaaa ttcatcctat ggtctatgtg ccgggcgtgt agaaatttac catggtggca
     6121 cctgggggac agtttgtgat gactcctgga ccattcagga agctgaggtg gtctgcagac
     6181 agctagggtg tggacgtgca gtttcagccc ttggaaatgc atattttggc tctggctctg
     6241 gccccatcac cctggacgat gtagagtgct cagggacgga atccactctc tggcagtgcc
     6301 ggaaccgagg ctggttctcc cacaactgta atcatcgtga agatgctggt gtcatctgct
     6361 caggaaacca tctatcgaca cctgctcctt ttctcaacat cacccgtcca aacacagatt
     6421 attcctgcgg aggcttccta tcccaaccat caggggactt ttccagccca ttctatcccg
     6481 ggaactatcc aaacaatgcc aagtgtgtgt gggacattga ggtgcaaaac aactaccgtg
     6541 tgactgtgat cttcagagat gtccagcttg aaggtggctg caactatgat tatattgaag
     6601 ttttcgatgg cccctaccgc agttcccctc tcattgctcg agtttgtgat ggggccagag
     6661 gctccttcac ttcttcctcc aacttcatgt ccattcgctt catcagtgac cacagcatca
     6721 caaggagagg gttccgggct gagtactact ccagtccctc caatgacagc accaacctgc
     6781 tctgtctgcc aaatcacatg caagccagtg tgagcaggag ctatctccaa tccttgggct
     6841 tttctgccag tgaccttgtc atttccacct ggaatggata ctacgagtgt cggccccaga
     6901 taacgccgaa cctggtgata ttcacaattc cctactcagg ctgcggcacc ttcaagcagg
     6961 cagacaatga caccatcgac tattccaact tcctcacagc agctgtctca ggtggcatca
     7021 tcaagaggag gacagacctc cgtattcacg tcagctgcag aatgcttcag aacacctggg
     7081 tcgacaccat gtacattgct aatgacacca tccacgttgc taataacacc atccaggtcg
     7141 aggaagtcca gtatggcaat tttgacgtga acatttcctt ttatacttcc tcatctttct
     7201 tgtatcctgt gaccagccgc ccttactacg tggacctgaa ccaggacttg tacgttcagg
     7261 ctgaaatcct ccattctgat gctgtactga ccttgtttgt ggacacctgc gtggcatcac
     7321 catactccaa tgacttcacg tctttgactt atgatctaat ccggagtgga tgcgtgaggg
     7381 atgacaccta cggaccctac tcctcgccat ctcttcgcat tgcccgcttc cggttcaggg
     7441 ccttccactt cctgaaccgc ttcccctccg tgtacctgcg ttgtaaaatg gtggtgtgca
     7501 gagcgtatga cccctcttcc cgctgctacc gaggctgtgt gttgaggtcg aagagggatg
     7561 tgggctccta ccaggaaaag gtggacgtcg tcctgggtcc catccagctg cagacccccc
     7621 cacgccgaga agaggagcct cggtaggtgg tcgctctcag accccactgt ccaccggggc
     7681 gcagacccct gactcgggga cttgggatgt tcctcttggt gtcatattcc aactcagatt
     7741 gagccctaca ttgtgctgca cctggtcata cggagttgaa tcagacctgg ttcccgcctc
     7801 ccccaaggct catggtcctt ggaggacccg ttgcagggtg aggtcaagag agttctgacc
     7861 tggatggccc atagacctga cgtcccagaa tccatgcttc tcatctgcaa aatgaaaatg
     7921 tcaatactta cttcttagca ctgttgagag ggttacttac ataaaggaat tttggtgaaa
     7981 ctgc
//
