LOCUS       XM_011534317            5881 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens DLEC1 cilia and flagella associated protein
            (DLEC1), transcript variant X1, mRNA.
ACCESSION   XM_011534317
VERSION     XM_011534317.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000003.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011534317.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5881
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
     gene            1..5881
                     /gene="DLEC1"
                     /gene_synonym="CFAP81; DLC-1; DLC1; F56; FAP81"
                     /note="DLEC1 cilia and flagella associated protein;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 1 mRNA, 51 ESTs, 11 long SRA reads, 2
                     Proteins, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 10 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:9940"
                     /db_xref="HGNC:HGNC:2899"
                     /db_xref="MIM:604050"
     CDS             19..5364
                     /gene="DLEC1"
                     /gene_synonym="CFAP81; DLC-1; DLC1; F56; FAP81"
                     /codon_start=1
                     /product="deleted in lung and esophageal cancer protein 1
                     isoform X1"
                     /protein_id="XP_011532619.1"
                     /db_xref="GeneID:9940"
                     /db_xref="HGNC:HGNC:2899"
                     /db_xref="MIM:604050"
                     /translation="METRSSKTRRSLASRTNECQGTMWAPTSPPAGSSSPSQPTWKSS
                     LYSSLAYSEAFHYSFAARPRRLTQLALAQRPEPQLLRLRPSSLRTQDISHLLTGVFRN
                     LYSAEVIGDEVSASLIKARGSENERHEEFVDQLQQIRELYKQRLDEFEMLERHITQAQ
                     ARAIAENERVMSQAGVQDLESLVRLPPVKSVSRWCIDSELLRKHHLISPEDYYTDTVP
                     FHSAPKGISLPGCSKLTFSCEKRSVQKKELNKKLEDSCRKKLAEFEDELDHTVDSLTW
                     NLTPKAKERTREPLKKASQPRNKNWMNHLRVPQRELDRLLLARMESRNHFLKNPRFFP
                     PNTRYGGKSLVFPPKKPAPIGEFQSTEPEQSCADTPVFLAKPPIGFFTDYEIGPVYEM
                     VIALQNTTTTSRYLRVLPPSTPYFALGLGMFPGKGGMVAPGMTCQYIVQFFPDCLGDF
                     DDFILVETQSAHTLLIPLQARRPPPVLTLSPVLDCGYCLIGGVKMTRFICKNVGFSVG
                     RFCIMPKTSWPPLSFKAIATVGFVEQPPFGILPSVFELAPGHAILVEVLFSPKSLGKA
                     EQTFIIMCDNCQIKELVTIGIGQLIALDLIYISGEKSQPDPGELTDLTAQHFIRFEPE
                     NLRSTARKQLIIRNATHVELAFYWQIMKPNLQPLMPGETFSMDSIKCYPDKETAFSIM
                     PRKGVLSPHTDHEFILSFSPHELRDFHSVLQMVLEEVPEPVSSEAESLGHSSYSVDDV
                     IVLEIEVKGSVEPFQVLLEPYALIIPGENYIGINVKKAFKMWNNSKSPIRYLWGKISD
                     CHIIEVEPGTGVIEPSEVGDFELNFTGGVPGPTSQDLLCEIEDSPSPVVLHIEAVFKG
                     PALIINVSALQFGLLRLGQKATNSIQIRNVSQLPATWRMKESPVSLQERPEDVSPFDI
                     EPSSGQLHSLGECRVDITLEALHCQHLETVLELEVENGAWSYLPVYAEVQKPHVYLQS
                     SQVEVRNLYLGVPTKTTITLINGTLLPTQFHWGKLLGHQAEFCMVTVSPKHGLLGPSE
                     ECQLKLELTAHTQEELTHLALPCHVSGMKKPLVLGISGKPQGLQVAITISKESSDCSV
                     FSTEQWPGHPKELRLDFGSAVPLRTRVTRQLILTNRSPIRTRFSLKFEYFGSPQNSLS
                     KKTSLPNMPPALLKTVRMQEHLAKREQLDFMESMLSHGKGAAFFPHFSQGMLGPYQQL
                     CIDITGCANMWGEYWDNLICTVGDLLPEVIPVHMAAVGCPISSLRTTSYTIDQAQKEP
                     AMRFGTQVSGGDTVTRTLRLNNSSPCDIRLDWETYVPEDKEDRLVELLVFYGPPFPLR
                     DQAGNELVCPDTPEGGCLLWSPGPSSSSEFSHETDSSVEGSSSASNRVAQKLISVILQ
                     AHEGVPSGHLYCISPKQVVVPAGGSSTIYISFTPMVLSPEILHKVECTGYALGFMSLD
                     SKVEREIPGKRHRLQDFAVGPLKLDLHSYVRPAQLSVELDYGGSMEFQCQASDLIPEQ
                     PCSGVLSELVTTHHLKLTNTTEIPHYFRLMVSRPFSVSQDGASQDHRAPGPGQKQECE
                     EETASADKQLVLQAQENMLVNVSFSLSLELLSYQKLPADQTLPGVDIQQSASGEREMV
                     FTQNLLLEYTNQTTQVVPLRAVVAVPELQLSTSWVDFGTCFVSQQRVREVYLMNLSGC
                     RSYWTMLMGVVSCTSPRWWWKVCSVRSPAPCGSGAKAPMMRDTCCLTSPEAPPQPSAP
                     GPSWRKNIAQGLGAALQHKDTDLGTWGPLGSSWNGRTPFHNGLSLGPHDMSSELT"
ORIGIN      
        1 agcggcgtct cggttgccat ggagaccagg agctccaaaa cgcggaggtc tttagcgtcc
       61 cggaccaacg agtgccaggg gacaatgtgg gcgccaactt cgccaccagc cgggtccagc
      121 agccccagcc agcccacctg gaagtcctcc ttgtattcct ccctcgccta ctctgaggcc
      181 ttccactaca gcttcgcagc ccggccccgc cgcctcacgc agcttgcgct ggcgcagcgt
      241 cccgagcctc agctgcttcg tctgcgcccc tcctcgctgc gcacccaaga tatctcgcac
      301 ttgctcaccg gcgtcttccg caacttgtac tcagccgagg tcatcggcga cgaagtgagc
      361 gcaagcttga tcaaggcccg cggcagcgag aatgagcgcc acgaggagtt cgtggaccag
      421 ctgcagcaga ttcgggagct ctataagcag cggctggatg agtttgaaat gttggagaga
      481 catatcactc aggcccaagc acgggctatt gcggaaaatg agcgggtcat gagccaggct
      541 ggagtacagg acctcgagag ccttgtcagg ttgcctccag tgaagagtgt ctccagatgg
      601 tgtatagaca gcgagttgct acggaaacat catttgatct ccccagaaga ttactacacc
      661 gatacagtgc cgtttcactc tgcacctaaa ggcatctccc tacctggatg ttcaaaactg
      721 acatttagct gtgagaagcg ttccgtccag aagaaagagc tgaacaagaa gcttgaagat
      781 tcatgcagga agaagcttgc tgagttcgaa gatgagttag accacactgt ggacagcctg
      841 acatggaatt taactcctaa ggccaaagaa aggaccagag aacctctcaa gaaagcaagt
      901 caaccaagga ataaaaactg gatgaaccac ttacgtgtgc cacagagaga gctagacaga
      961 cttctgcttg ccagaatgga gagtcggaac cacttcctaa aaaatccccg tttttttcct
     1021 cctaacactc gatatggagg caagtctctt gtttttcctc caaagaagcc agcaccgata
     1081 ggagaattcc agagtacaga gccagaacag agttgtgctg atactccagt gtttctagct
     1141 aagccaccaa ttgggttttt cacagattat gaaattggtc cagtttatga gatggtaatt
     1201 gcgctgcaga acaccaccac gaccagccgc tacctgcgag tcctcccgcc ttccacgcca
     1261 tacttcgctc tgggactggg gatgttccca ggaaaaggtg gaatggtggc tcctggaatg
     1321 acctgccagt acattgtcca gttttttccc gactgccttg gggattttga tgattttatt
     1381 ttagtggaga cccagtcagc ccacacactt ctgatccccc tgcaggcccg gaggccgccc
     1441 cccgtgctga cattgtcacc ggtgttggac tgtggttact gcctcattgg gggagtcaag
     1501 atgaccagat tcatctgcaa aaatgtgggt ttcagtgttg gcaggttctg cattatgccc
     1561 aaaacaagct ggccaccact aagtttcaag gccattgcaa ccgtcggctt tgttgaacaa
     1621 cctccttttg gaatcctgcc ttcggtgttt gagctggccc cgggacatgc tatattagtg
     1681 gaggtcttgt tttccccaaa gagcctagga aaggcagagc agaccttcat catcatgtgc
     1741 gacaactgcc agataaagga gctggtgacc ataggaattg ggcagctgat tgctttggat
     1801 ctgatctata tttctggtga aaaaagccag ccagaccctg gagagctcac agacttaaca
     1861 gcccagcact tcatacgatt tgagcctgaa aaccttcggt ccacggctag gaagcagctg
     1921 attattagaa atgctacgca cgtggagctg gccttctact ggcagatcat gaagcccaac
     1981 ctgcagcccc tcatgcctgg agaaaccttc agcatggaca gcatcaagtg ctaccccgac
     2041 aaggagactg ccttctccat catgcccaga aagggggttc taagccccca cacagaccac
     2101 gagttcatcc tgagcttttc tcctcatgag ctgagggatt ttcacagtgt gctccagatg
     2161 gtgctagagg aagtcccaga gcctgtaagt tcagaagcgg agagcctggg gcactcctcc
     2221 tactctgtgg atgatgtgat tgtcctggaa atcgaggtga aaggctcagt agaacctttc
     2281 caggttctct tagagccata tgccctcatc atcccagggg agaactacat tgggataaat
     2341 gtgaagaagg cttttaagat gtggaacaac agcaagtcac ccatcagata cctgtggggg
     2401 aagatcagcg actgccacat cattgaagtg gagcccggca caggggtcat agagcccagt
     2461 gaggtcgggg attttgagtt gaactttact gggggtgtcc ctggccccac aagccaggac
     2521 ctgctgtgtg aaatcgaaga ctcgccctcg ccagtggtgt tacacattga ggctgtcttt
     2581 aaggggcctg ccctcatcat caacgtctca gcccttcagt ttggtctgct ccgcctgggg
     2641 cagaaagcca caaactccat ccagatccgg aacgtcagcc agctcccagc cacatggcgc
     2701 atgaaggaga gcccagtctc cctccaggaa aggcctgagg atgtgtctcc cttcgacatt
     2761 gagccttcga gtggccagct tcactctctg ggggagtgca gggtggacat caccttggag
     2821 gccctgcact gccagcatct ggagaccgtc ctggagctgg aggtggaaaa tggtgcctgg
     2881 agctaccttc ctgtgtatgc tgaggtacag aagccccatg tgtacctaca gagcagccag
     2941 gtggaggtta gaaatctcta cctgggtgtg cccacgaaga caaccatcac acttatcaat
     3001 ggcacgctcc tgcctaccca gttccactgg ggcaagctcc tcggacacca agcagaattc
     3061 tgcatggtga cagtctcccc caaacatggc ctgctgggcc caagtgagga gtgccagctc
     3121 aagttggagt tgactgctca tacccaggaa gagctgaccc atctggccct cccttgtcac
     3181 gtgtcaggca tgaagaagcc actggttcta ggcatttctg ggaagcccca gggactgcaa
     3241 gtggccatta ccatctctaa ggagagctct gattgcagtg ttttcagcac agagcagtgg
     3301 ccaggccacc caaaggagct ccgcctggac tttggctcag cggtgccact gaggacccgt
     3361 gtgactcgcc agctcattct caccaatcgc tccccaatac ggacccgttt ctccctcaag
     3421 tttgagtatt tcgggagccc ccaaaacagc ctgagcaaaa agaccagcct tcccaacatg
     3481 cctcctgccc tgctaaagac agtgcggatg caagagcacc tggccaagcg agagcagctg
     3541 gattttatgg agagcatgct atcccacggg aaaggagctg ctttcttccc tcacttttcc
     3601 cagggcatgc tggggcccta ccagcagctg tgcattgaca tcacaggctg tgccaacatg
     3661 tggggcgagt actgggacaa cctcatctgc acggtgggag acctgctgcc ggaagtcatc
     3721 ccagtgcaca tggcagcggt gggctgcccc atcagctccc tgaggaccac ctcctacact
     3781 attgaccagg cccagaagga accagccatg aggttcggca cccaggtctc cggaggagac
     3841 acagttaccc gaacccttcg cctgaataac tccagcccct gtgacatccg cctggattgg
     3901 gagacctatg ttccagaaga caaggaagac cggctggtgg agctgctggt gttttatggg
     3961 ccacctttcc cgctgcggga ccaagccggg aatgagcttg tgtgccctga tacccctgag
     4021 ggtggctgcc tcctctggtc cccaggcccc tccagttcat cggaattcag ccatgaaact
     4081 gactcatcag ttgagggcag ctccagtgcc agcaataggg tggcacagaa gctcatctca
     4141 gtcatcctgc aggcacatga gggggtgccc tccggccacc tgtactgtat cagccccaag
     4201 caggtggtgg tccctgctgg gggcagcagt accatctaca tctccttcac ccctatggtg
     4261 ctcagccctg agatcctgca caaggtggag tgtactggct acgccctggg tttcatgagc
     4321 ttggacagca aggtggaaag ggagattcca gggaagaggc atcgcctgca ggactttgcg
     4381 gtgggacccc tgaaactgga cctgcatagc tacgtgaggc ctgcacagct aagtgtggag
     4441 ctggactacg gcggcagtat ggaattccag tgccaggcca gtgacctcat tcccgagcag
     4501 ccctgctctg gggtgctgag tgagctggtg accacccacc acctgaagct gaccaacact
     4561 acagagatcc cacactactt ccggcttatg gtctccaggc ccttctccgt ttctcaagat
     4621 ggggcgagcc aggaccacag agctcctggc cctggccaga agcaggagtg tgaggaggag
     4681 acagcctcag cggacaagca gctggtgctc caagcacagg agaacatgct ggtgaacgtg
     4741 tccttctcac tctccctgga gctgctctcc tatcagaagc tcccagctga ccagacactg
     4801 cctggggtgg acattcagca gagtgcgagt ggagagagag agatggtgtt tactcagaac
     4861 ctgctcctgg agtacaccaa ccagaccact caggtggtgc ccctgcgggc tgtggtggcc
     4921 gtgcctgagc tgcagctctc caccagctgg gtggactttg ggacctgctt tgtgagccag
     4981 cagcgagtcc gggaggtcta cctgatgaac ctgagcgggt gccgaagcta ctggactatg
     5041 ctgatgggag tagtgagctg tacgagtcca cgatggtggt ggaaggtgtg ctcggtgaga
     5101 agtcctgcac cctgcggctc cggggccaag gctcctatga tgagagatac atgttgcctc
     5161 accagccctg aggctccgcc ccagccctca gccccaggcc ccagctggag aaaaaacatt
     5221 gcccagggat taggagcagc tcttcagcac aaagacacag acttggggac ctggggacct
     5281 ctgggcagct cctggaatgg aagaaccccc ttccacaatg gtctcagcct aggccctcat
     5341 gatatgtcct cagagctaac ataaaggaca ggccacacca cagcagagac caccacattg
     5401 agatcactac tcagtgcata gcgaagacca gtatggcaaa attagtcttg gaaaaaaacc
     5461 acagccacta agataaattc atgcactttt actatgccca ttgcacttct catccatgga
     5521 tttgccttgc cttaagaatt aaccatggcc ttgtggcctg ggtgacccag gctgctttta
     5581 tcttgcacag ctaaagaggg tctgatgggt ggctcaacac cccacccact cctataccat
     5641 gtcatcagtg ttcacatttt ccaaatgagt tgaagtgcct tgatctgtcc actgccacca
     5701 ccaccagtgc tgagttttcc catgtggttt tgcttttgtg gtgttactgc cttgctgcta
     5761 gagcagcagg actgtctgcg tagcgcctcc agcctgggac ctcactcagt tcccagggta
     5821 ttcaaagacg gcagcggctc ccattccagt cccgatgcac atggacacca ctccgtatgc
     5881 c
//
