LOCUS       NM_001195257             240 bp    mRNA    linear   PRI 01-JUN-2024
DEFINITION  Homo sapiens defensin beta 130B (DEFB130B), mRNA.
ACCESSION   NM_001195257 XM_001721606
VERSION     NM_001195257.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 240)
  AUTHORS   Terkawi,M.A., Takano,R., Furukawa,A., Murakoshi,F. and Kato,K.
  TITLE     Involvement of beta-defensin 130 (DEFB130) in the macrophage
            microbicidal mechanisms for killing Plasmodium falciparum
  JOURNAL   Sci Rep 7, 41772 (2017)
   PUBMED   28181499
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC130366.6.
            
            On Sep 1, 2010 this sequence version replaced XM_001721606.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000437818.1/ ENSP00000392568.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-58                AC130366.6         103887-103944
            59-240              AC130366.6         111064-111245
FEATURES             Location/Qualifiers
     source          1..240
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="8"
                     /map="8p23.1"
     gene            1..240
                     /gene="DEFB130B"
                     /note="defensin beta 130B"
                     /db_xref="GeneID:100133267"
                     /db_xref="HGNC:HGNC:39814"
     CDS             1..240
                     /gene="DEFB130B"
                     /note="defensin, beta 130-like; beta-defensin 130-like;
                     beta-defensin 130B"
                     /codon_start=1
                     /product="beta-defensin 130B precursor"
                     /protein_id="NP_001182186.1"
                     /db_xref="CCDS:CCDS56524.1"
                     /db_xref="GeneID:100133267"
                     /db_xref="HGNC:HGNC:39814"
                     /translation="MKLHSLISVLLLFVTLIPKGKTGVIPGQKQCIALKGVCRDKLCS
                     TLDDTIGICNEGKKCCRRWWILEPYPTPVPKGKSP"
     exon            1..58
                     /gene="DEFB130B"
                     /inference="alignment:Splign:2.1.0"
     exon            59..240
                     /gene="DEFB130B"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgaaactcc attcccttat ttctgttctc ctcctctttg tgactttaat accaaaagga
       61 aagactggcg ttattccagg acaaaaacag tgtattgctt tgaaaggggt gtgcagagac
      121 aaactatgca gcacactaga tgataccatt ggtatatgta atgaaggaaa aaaatgttgt
      181 agaaggtggt ggatacttga gccctatcca actccggttc ccaaaggaaa atctccttag
//
