LOCUS       NM_001366458            3614 bp    mRNA    linear   PRI 06-APR-2024
DEFINITION  Homo sapiens discoidin, CUB and LCCL domain containing 1 (DCBLD1),
            transcript variant 1, mRNA.
ACCESSION   NM_001366458 XM_005266941
VERSION     NM_001366458.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3614)
  AUTHORS   Meng,Q., Sun,H., Zhang,Y., Yang,X., Hao,S., Liu,B., Zhou,H.,
            Xu,Z.X. and Wang,Y.
  TITLE     Lactylation stabilizes DCBLD1 activating the pentose phosphate
            pathway to promote cervical cancer progression
  JOURNAL   J Exp Clin Cancer Res 43 (1), 36 (2024)
   PUBMED   38291438
  REMARK    GeneRIF: Lactylation stabilizes DCBLD1 activating the pentose
            phosphate pathway to promote cervical cancer progression.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3614)
  AUTHORS   Chongtham,J., Pandey,N., Sharma,L.K., Mohan,A. and Srivastava,T.
  TITLE     SNP rs9387478 at ROS1-DCBLD1 Locus is Significantly Associated with
            Lung Cancer Risk and Poor Survival in Indian Population
  JOURNAL   Asian Pac J Cancer Prev 23 (10), 3553-3561 (2022)
   PUBMED   36308382
  REMARK    GeneRIF: SNP rs9387478 at ROS1-DCBLD1 Locus is Significantly
            Associated with Lung Cancer Risk and Poor Survival in Indian
            Population.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3614)
  AUTHORS   Cardin,G.B., Bernard,M., Rodier,F. and Christopoulos,A.
  TITLE     DCBLD1 is associated with the integrin signaling pathway and has
            prognostic value in non-small cell lung and invasive breast
            carcinoma
  JOURNAL   Sci Rep 11 (1), 12753 (2021)
   PUBMED   34140574
  REMARK    GeneRIF: DCBLD1 is associated with the integrin signaling pathway
            and has prognostic value in non-small cell lung and invasive breast
            carcinoma.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3614)
  AUTHORS   Schmoker,A.M., Weinert,J.L., Markwood,J.M., Albretsen,K.S.,
            Lunde,M.L., Weir,M.E., Ebert,A.M., Hinkle,K.L. and Ballif,B.A.
  TITLE     FYN and ABL Regulate the Interaction Networks of the DCBLD Receptor
            Family
  JOURNAL   Mol Cell Proteomics 19 (10), 1586-1601 (2020)
   PUBMED   32606017
  REMARK    GeneRIF: FYN and ABL Regulate the Interaction Networks of the DCBLD
            Receptor Family.
REFERENCE   5  (bases 1 to 3614)
  AUTHORS   Wang,Y., Ma,R., Liu,B., Kong,J., Lin,H., Yu,X., Wang,R., Li,L.,
            Gao,M., Zhou,B., Mohan,M., Yu,H., Hou,Z., Shen,H. and Qian,B.
  TITLE     SNP rs17079281 decreases lung cancer risk through creating an
            YY1-binding site to suppress DCBLD1 expression
  JOURNAL   Oncogene 39 (20), 4092-4102 (2020)
   PUBMED   32231272
  REMARK    GeneRIF: SNP rs17079281 decreases lung cancer risk through creating
            an YY1-binding site to suppress DCBLD1 expression.
REFERENCE   6  (bases 1 to 3614)
  AUTHORS   Han,J.Y., Lee,Y.S., Shin,E.S., Hwang,J.A., Nam,S., Hong,S.H.,
            Ghang,H.Y., Kim,J.Y., Yoon,S.J. and Lee,J.S.
  TITLE     A genome-wide association study of survival in small-cell lung
            cancer patients treated with irinotecan plus cisplatin chemotherapy
  JOURNAL   Pharmacogenomics J 14 (1), 20-27 (2014)
   PUBMED   23478653
REFERENCE   7  (bases 1 to 3614)
  AUTHORS   Peters,U., Jiao,S., Schumacher,F.R., Hutter,C.M., Aragaki,A.K.,
            Baron,J.A., Berndt,S.I., Bezieau,S., Brenner,H., Butterbach,K.,
            Caan,B.J., Campbell,P.T., Carlson,C.S., Casey,G., Chan,A.T.,
            Chang-Claude,J., Chanock,S.J., Chen,L.S., Coetzee,G.A.,
            Coetzee,S.G., Conti,D.V., Curtis,K.R., Duggan,D., Edwards,T.,
            Fuchs,C.S., Gallinger,S., Giovannucci,E.L., Gogarten,S.M.,
            Gruber,S.B., Haile,R.W., Harrison,T.A., Hayes,R.B., Henderson,B.E.,
            Hoffmeister,M., Hopper,J.L., Hudson,T.J., Hunter,D.J.,
            Jackson,R.D., Jee,S.H., Jenkins,M.A., Jia,W.H., Kolonel,L.N.,
            Kooperberg,C., Kury,S., Lacroix,A.Z., Laurie,C.C., Laurie,C.A., Le
            Marchand,L., Lemire,M., Levine,D., Lindor,N.M., Liu,Y., Ma,J.,
            Makar,K.W., Matsuo,K., Newcomb,P.A., Potter,J.D., Prentice,R.L.,
            Qu,C., Rohan,T., Rosse,S.A., Schoen,R.E., Seminara,D.,
            Shrubsole,M., Shu,X.O., Slattery,M.L., Taverna,D., Thibodeau,S.N.,
            Ulrich,C.M., White,E., Xiang,Y., Zanke,B.W., Zeng,Y.X., Zhang,B.,
            Zheng,W. and Hsu,L.
  CONSRTM   Colon Cancer Family Registry and the Genetics and Epidemiology of
            Colorectal Cancer Consortium
  TITLE     Identification of Genetic Susceptibility Loci for Colorectal Tumors
            in a Genome-Wide Meta-analysis
  JOURNAL   Gastroenterology 144 (4), 799-807 (2013)
   PUBMED   23266556
  REMARK    Review article
REFERENCE   8  (bases 1 to 3614)
  AUTHORS   Lan,Q., Hsiung,C.A., Matsuo,K., Hong,Y.C., Seow,A., Wang,Z.,
            Hosgood,H.D. 3rd, Chen,K., Wang,J.C., Chatterjee,N., Hu,W.,
            Wong,M.P., Zheng,W., Caporaso,N., Park,J.Y., Chen,C.J., Kim,Y.H.,
            Kim,Y.T., Landi,M.T., Shen,H., Lawrence,C., Burdett,L., Yeager,M.,
            Yuenger,J., Jacobs,K.B., Chang,I.S., Mitsudomi,T., Kim,H.N.,
            Chang,G.C., Bassig,B.A., Tucker,M., Wei,F., Yin,Z., Wu,C., An,S.J.,
            Qian,B., Lee,V.H., Lu,D., Liu,J., Jeon,H.S., Hsiao,C.F., Sung,J.S.,
            Kim,J.H., Gao,Y.T., Tsai,Y.H., Jung,Y.J., Guo,H., Hu,Z.,
            Hutchinson,A., Wang,W.C., Klein,R., Chung,C.C., Oh,I.J., Chen,K.Y.,
            Berndt,S.I., He,X., Wu,W., Chang,J., Zhang,X.C., Huang,M.S.,
            Zheng,H., Wang,J., Zhao,X., Li,Y., Choi,J.E., Su,W.C., Park,K.H.,
            Sung,S.W., Shu,X.O., Chen,Y.M., Liu,L., Kang,C.H., Hu,L.,
            Chen,C.H., Pao,W., Kim,Y.C., Yang,T.Y., Xu,J., Guan,P., Tan,W.,
            Su,J., Wang,C.L., Li,H., Sihoe,A.D., Zhao,Z., Chen,Y., Choi,Y.Y.,
            Hung,J.Y., Kim,J.S., Yoon,H.I., Cai,Q., Lin,C.C., Park,I.K., Xu,P.,
            Dong,J., Kim,C., He,Q., Perng,R.P., Kohno,T., Kweon,S.S.,
            Chen,C.Y., Vermeulen,R., Wu,J., Lim,W.Y., Chen,K.C., Chow,W.H.,
            Ji,B.T., Chan,J.K., Chu,M., Li,Y.J., Yokota,J., Li,J., Chen,H.,
            Xiang,Y.B., Yu,C.J., Kunitoh,H., Wu,G., Jin,L., Lo,Y.L.,
            Shiraishi,K., Chen,Y.H., Lin,H.C., Wu,T., Wu,Y.L., Yang,P.C.,
            Zhou,B., Shin,M.H., Fraumeni,J.F. Jr., Lin,D., Chanock,S.J. and
            Rothman,N.
  TITLE     Genome-wide association analysis identifies new lung cancer
            susceptibility loci in never-smoking women in Asia
  JOURNAL   Nat Genet 44 (12), 1330-1335 (2012)
   PUBMED   23143601
REFERENCE   9  (bases 1 to 3614)
  AUTHORS   Benjamin,D.J., Cesarini,D., van der Loos,M.J., Dawes,C.T.,
            Koellinger,P.D., Magnusson,P.K., Chabris,C.F., Conley,D.,
            Laibson,D., Johannesson,M. and Visscher,P.M.
  TITLE     The genetic architecture of economic and political preferences
  JOURNAL   Proc Natl Acad Sci U S A 109 (21), 8026-8031 (2012)
   PUBMED   22566634
REFERENCE   10 (bases 1 to 3614)
  AUTHORS   Mungall,A.J., Palmer,S.A., Sims,S.K., Edwards,C.A., Ashurst,J.L.,
            Wilming,L., Jones,M.C., Horton,R., Hunt,S.E., Scott,C.E.,
            Gilbert,J.G., Clamp,M.E., Bethel,G., Milne,S., Ainscough,R.,
            Almeida,J.P., Ambrose,K.D., Andrews,T.D., Ashwell,R.I.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Barker,D.J.,
            Barlow,K.F., Bates,K., Beare,D.M., Beasley,H., Beasley,O.,
            Bird,C.P., Blakey,S., Bray-Allen,S., Brook,J., Brown,A.J.,
            Brown,J.Y., Burford,D.C., Burrill,W., Burton,J., Carder,C.,
            Carter,N.P., Chapman,J.C., Clark,S.Y., Clark,G., Clee,C.M.,
            Clegg,S., Cobley,V., Collier,R.E., Collins,J.E., Colman,L.K.,
            Corby,N.R., Coville,G.J., Culley,K.M., Dhami,P., Davies,J.,
            Dunn,M., Earthrowl,M.E., Ellington,A.E., Evans,K.A., Faulkner,L.,
            Francis,M.D., Frankish,A., Frankland,J., French,L., Garner,P.,
            Garnett,J., Ghori,M.J., Gilby,L.M., Gillson,C.J., Glithero,R.J.,
            Grafham,D.V., Grant,M., Gribble,S., Griffiths,C., Griffiths,M.,
            Hall,R., Halls,K.S., Hammond,S., Harley,J.L., Hart,E.A.,
            Heath,P.D., Heathcott,R., Holmes,S.J., Howden,P.J., Howe,K.L.,
            Howell,G.R., Huckle,E., Humphray,S.J., Humphries,M.D., Hunt,A.R.,
            Johnson,C.M., Joy,A.A., Kay,M., Keenan,S.J., Kimberley,A.M.,
            King,A., Laird,G.K., Langford,C., Lawlor,S., Leongamornlert,D.A.,
            Leversha,M., Lloyd,C.R., Lloyd,D.M., Loveland,J.E., Lovell,J.,
            Martin,S., Mashreghi-Mohammadi,M., Maslen,G.L., Matthews,L.,
            McCann,O.T., McLaren,S.J., McLay,K., McMurray,A., Moore,M.J.,
            Mullikin,J.C., Niblett,D., Nickerson,T., Novik,K.L., Oliver,K.,
            Overton-Larty,E.K., Parker,A., Patel,R., Pearce,A.V., Peck,A.I.,
            Phillimore,B., Phillips,S., Plumb,R.W., Porter,K.M., Ramsey,Y.,
            Ranby,S.A., Rice,C.M., Ross,M.T., Searle,S.M., Sehra,H.K.,
            Sheridan,E., Skuce,C.D., Smith,S., Smith,M., Spraggon,L.,
            Squares,S.L., Steward,C.A., Sycamore,N., Tamlyn-Hall,G., Tester,J.,
            Theaker,A.J., Thomas,D.W., Thorpe,A., Tracey,A., Tromans,A.,
            Tubby,B., Wall,M., Wallis,J.M., West,A.P., White,S.S.,
            Whitehead,S.L., Whittaker,H., Wild,A., Willey,D.J., Wilmer,T.E.,
            Wood,J.M., Wray,P.W., Wyatt,J.C., Young,L., Younger,R.M.,
            Bentley,D.R., Coulson,A., Durbin,R., Hubbard,T., Sulston,J.E.,
            Dunham,I., Rogers,J. and Beck,S.
  TITLE     The DNA sequence and analysis of human chromosome 6
  JOURNAL   Nature 425 (6960), 805-811 (2003)
   PUBMED   14574404
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL132671.20 and Z85999.1.
            
            On Jun 2, 2019 this sequence version replaced NM_001366458.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7346977.1674089.1,
                                           SRR6380202.27560.17 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000338728.10/ ENSP00000342422.6
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-220               AL132671.20        4742-4961           c
            221-433             Z85999.1           16233-16445
            434-568             Z85999.1           32282-32416
            569-620             Z85999.1           33991-34042
            621-693             Z85999.1           37828-37900
            694-827             Z85999.1           44726-44859
            828-868             Z85999.1           49651-49691
            869-1084            Z85999.1           51086-51301
            1085-1209           Z85999.1           51721-51845
            1210-1357           Z85999.1           53134-53281
            1358-1465           Z85999.1           53384-53491
            1466-1553           Z85999.1           55590-55677
            1554-1603           Z85999.1           56994-57043
            1604-1723           Z85999.1           57944-58063
            1724-3614           Z85999.1           60373-62263
FEATURES             Location/Qualifiers
     source          1..3614
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6q22.1"
     gene            1..3614
                     /gene="DCBLD1"
                     /gene_synonym="dJ94G16.1"
                     /note="discoidin, CUB and LCCL domain containing 1"
                     /db_xref="GeneID:285761"
                     /db_xref="HGNC:HGNC:21479"
     exon            1..220
                     /gene="DCBLD1"
                     /gene_synonym="dJ94G16.1"
                     /inference="alignment:Splign:2.1.0"
     CDS             109..2256
                     /gene="DCBLD1"
                     /gene_synonym="dJ94G16.1"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; discoidin, CUB and LCCL domain-containing
                     protein 1"
                     /codon_start=1
                     /product="discoidin, CUB and LCCL domain-containing
                     protein 1 isoform 1 precursor"
                     /protein_id="NP_001353387.1"
                     /db_xref="CCDS:CCDS93995.1"
                     /db_xref="GeneID:285761"
                     /db_xref="HGNC:HGNC:21479"
                     /translation="MVPGARGGGALARAAGRGLLALLLAVSAPLRLQAEELGDGCGHL
                     VTYQDSGTMTSKNYPGTYPNHTVCEKTITVPKGKRLILRLGDLDIESQTCASDYLLFT
                     SSSDQYGPYCGSMTVPKELLLNTSEVTVRFESGSHISGRGFLLTYASSDHPDLITCLE
                     RASHYLKTEYSKFCPAGCRDVAGDISGNMVDGYRDTSLLCKAAIHAGIIADELGGQIS
                     VLQRKGISRYEGILANGVLSRDGSLSDKRFLFTSNGCSRSLSFEPDGQIRASSSWQSV
                     NESGDQVHWSPGQARLQDQGPSWASGDSSNNHKPREWLEIDLGEKKKITGIRTTGSTQ
                     SNFNFYVKSFVMNFKNNNSKWKTYKGIVNNEEKVFQGNSNFRDPVQNNFIPPIVARYV
                     RVVPQTWHQRIALKVELIGCQITQGNDSLVWRKTSQSTSVSTKKEDETITRPIPSEET
                     STGINITTVAIPLVLLVVLVFAGMGIFAAFRKKKKKGSPYGSAEAQKTDCWKQIKYPF
                     ARHQSAEFTISYDNEKEMTQKLDLITSDMADYQQPLMIGTGTVTRKGSTFRPMDTDAE
                     EAGVSTDAGGHYDCPQRAGRHEYALPLAPPEPEYATPIVERHVLRAHTFSAQSGYRVP
                     GPQPGHKHSLSSGGFSPVAGVGAQDGDYQRPHSAQPADRGYDRPKAVSALATESGHPD
                     SQKPPTHPGTSDSYSAPRDCLTPLNQTAMTALL"
     exon            221..433
                     /gene="DCBLD1"
                     /gene_synonym="dJ94G16.1"
                     /inference="alignment:Splign:2.1.0"
     exon            434..568
                     /gene="DCBLD1"
                     /gene_synonym="dJ94G16.1"
                     /inference="alignment:Splign:2.1.0"
     exon            569..620
                     /gene="DCBLD1"
                     /gene_synonym="dJ94G16.1"
                     /inference="alignment:Splign:2.1.0"
     exon            621..693
                     /gene="DCBLD1"
                     /gene_synonym="dJ94G16.1"
                     /inference="alignment:Splign:2.1.0"
     exon            694..827
                     /gene="DCBLD1"
                     /gene_synonym="dJ94G16.1"
                     /inference="alignment:Splign:2.1.0"
     exon            828..868
                     /gene="DCBLD1"
                     /gene_synonym="dJ94G16.1"
                     /inference="alignment:Splign:2.1.0"
     exon            869..1084
                     /gene="DCBLD1"
                     /gene_synonym="dJ94G16.1"
                     /inference="alignment:Splign:2.1.0"
     exon            1085..1209
                     /gene="DCBLD1"
                     /gene_synonym="dJ94G16.1"
                     /inference="alignment:Splign:2.1.0"
     exon            1210..1357
                     /gene="DCBLD1"
                     /gene_synonym="dJ94G16.1"
                     /inference="alignment:Splign:2.1.0"
     exon            1358..1465
                     /gene="DCBLD1"
                     /gene_synonym="dJ94G16.1"
                     /inference="alignment:Splign:2.1.0"
     exon            1466..1553
                     /gene="DCBLD1"
                     /gene_synonym="dJ94G16.1"
                     /inference="alignment:Splign:2.1.0"
     exon            1554..1603
                     /gene="DCBLD1"
                     /gene_synonym="dJ94G16.1"
                     /inference="alignment:Splign:2.1.0"
     exon            1604..1723
                     /gene="DCBLD1"
                     /gene_synonym="dJ94G16.1"
                     /inference="alignment:Splign:2.1.0"
     exon            1724..3614
                     /gene="DCBLD1"
                     /gene_synonym="dJ94G16.1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3594..3599
                     /regulatory_class="polyA_signal_sequence"
                     /gene="DCBLD1"
                     /gene_synonym="dJ94G16.1"
                     /note="hexamer: AATAAA"
     polyA_site      3614
                     /gene="DCBLD1"
                     /gene_synonym="dJ94G16.1"
                     /note="major polyA site"
ORIGIN      
        1 gtcccggcgc cgcgctcgtc cgcagaggag gcggcccggc ccgggcagct gcggctcggg
       61 atccgtcgag gggaggccga gcttgccaag ctggcgccca gcggggtcat ggtgcccggc
      121 gcccgcggcg gcggcgcact ggcgcgggct gccgggcggg gcctcctggc tttgctgctc
      181 gcggtctccg ccccgctccg gctgcaggcg gaggagctgg gtgatggctg tggacaccta
      241 gtgacttatc aggatagtgg cacaatgaca tctaagaatt atcccgggac ctaccccaat
      301 cacactgttt gcgaaaagac aattacagta ccaaagggga aaagactgat tctgaggttg
      361 ggagatttgg atatcgaatc ccagacctgt gcttctgact atcttctctt caccagctct
      421 tcagatcaat atggtccata ctgtggaagt atgactgttc ccaaagaact cttgttgaac
      481 acaagtgaag taaccgtccg ctttgagagt ggatcccaca tttctggccg gggttttttg
      541 ctgacctatg cgagcagcga ccatccagat ttaataacat gtttggaacg agctagccat
      601 tatttgaaga cagaatacag caaattctgc ccagctggtt gtagagacgt agcaggagac
      661 atttctggga atatggtaga tggatataga gatacctctt tattgtgcaa agctgccatc
      721 catgcaggaa taattgctga tgaactaggt ggccagatca gtgtgcttca gcgcaaaggg
      781 atcagtcgat atgaagggat tctggccaat ggtgttcttt cgagggatgg ttccctgtca
      841 gacaagcgat ttctgtttac ctccaatggt tgcagcagat ccttgagttt tgaacctgac
      901 gggcaaatca gagcttcttc ctcatggcag tcggtcaatg agagtggaga ccaagttcac
      961 tggtctcctg gccaagcccg acttcaggac caaggcccat catgggcttc gggcgacagt
     1021 agcaacaacc acaaaccacg agagtggctg gagatcgatt tgggggagaa aaagaaaata
     1081 acaggaatta ggaccacagg atctacacag tcgaacttca acttttatgt taagagtttt
     1141 gtgatgaact tcaaaaacaa taattctaag tggaagacct ataaaggaat tgtgaataat
     1201 gaagaaaagg tgtttcaggg taactctaac tttcgggacc cagtgcaaaa caatttcatc
     1261 cctcccatcg tggccagata tgtgcgggtt gtcccccaga catggcacca gaggatagcc
     1321 ttgaaggtgg agctcattgg ttgccagatt acacaaggta atgattcatt ggtgtggcgc
     1381 aagacaagtc aaagcaccag tgtttcaact aagaaagaag atgagacaat cacaaggccc
     1441 atcccctcgg aagaaacatc cacaggaata aacattacaa cggtggctat tccattggtg
     1501 ctccttgttg tcctggtgtt tgctggaatg gggatctttg cagcctttag aaagaagaag
     1561 aagaaaggaa gtccgtatgg atcagcagag gctcagaaaa cagactgttg gaagcagatt
     1621 aaatatccct ttgccagaca tcagtcagct gagtttacca tcagctatga taatgagaag
     1681 gagatgacac aaaagttaga tctcatcaca agtgatatgg cagattacca gcagcccctc
     1741 atgattggca ccgggacagt cacgaggaag ggctccacct tccggcccat ggacacggat
     1801 gccgaggagg caggggtgag caccgatgcc ggcggccact atgactgccc gcagcgggcc
     1861 ggccgccacg agtacgcgct gcccctggcg cccccggagc ccgagtacgc cacgcccatc
     1921 gtggagcggc acgtgctgcg cgcccacacg ttctctgcgc agagcggcta ccgcgtccca
     1981 gggccccagc ccggccacaa acactccctc tcctcgggcg gcttctcccc cgtagcgggt
     2041 gtgggcgccc aggacggaga ctatcaaagg ccacacagcg cacagcctgc ggacaggggc
     2101 tacgaccggc ccaaagctgt cagcgccctc gccaccgaaa gcgggcaccc tgactctcag
     2161 aagcccccaa cgcatcccgg gacgagtgac agctattctg cccccagaga ctgcctcaca
     2221 cccctcaacc agacggccat gactgccctt ttgtgaacac aatgtgaaag aagcctgctg
     2281 tggtactgag cgtcgggctg tcacaaggca ctggaagaag ggagcctgct ggtccagagt
     2341 gtgcgtgtgt atcggtgtgt gtgtacactt gcatgtgtgt gtgtgatcca gtaggatcct
     2401 agagacaacc tgtcatactg tttacaaaat tgtgcagctg gtttcgtgct gacccttagg
     2461 gtgcgtctgt tgggttttgt tgggctagaa aaatgaaaat tttcagatgg cgttttcatt
     2521 cctctgactg atattgagct gctttggtgt taaaggtgta atgtgtacag agttgtattt
     2581 aacaataata aaagtaactt aagtttgctc tatcagattt tagttctgca cagaggttaa
     2641 gtgggaaaat gcagctgttg caaaatgtat ataaatagta tgttcatttt tttcagtata
     2701 ttatctgata ctgtgttagc agcaggtctg cttaaaccta gtcttgttgt tattgagtca
     2761 tttcctctcc tttgataact agaactgaaa gcatttttaa cattcttctc ctggaagaaa
     2821 tgaattactt gaagcatgaa aagcacacca gggtggttgt ttatttagca attatgactg
     2881 tagatttaaa aacaagcaaa gaaacaacac ctcagcagct gcccgtttcc ttagtctcca
     2941 cttcagaggg ggatgcgaag aggtcggccc agctccggtg accatgaagg tggcacagga
     3001 attacagtgt gaatggctgt gtcagatgtt ttcgtacctc agattaaaaa tattgctgag
     3061 gtcagacgcc acaattttca tgactttctt cagaagtagc acattttcgt gacttccgct
     3121 gtcctctgaa aaacaaagtt atttggaaca tgttcatgca aaagtgattc tgaccaagtc
     3181 taaatcgagc ttttctactg acatgaaact gttggaaact gatctcattt tataagaaat
     3241 gattttcccc tcaaggaggc gtctgtaatt ccagaacagt ccagacatca gctgtacctc
     3301 atgctcagta gtttttattt gagtttcttt tgtgagttaa ctatgggaga tttaacctct
     3361 tttgccaaag agggaagtgt gtgtgttttt ttaatagaaa atatggacca aaaatttttt
     3421 tccctgaaga atgtattata accctatttg tgtggttatt acatcctgtg aaatgtatat
     3481 atgttaaaat aatgggggtg ctggaaggtc atggcagact agctgctggt tagtgtggag
     3541 gggaaatggt ttactttgta gagtttacat ggttttatgc gcacactaat tgtaataaac
     3601 tatgccaaac caaa
//
