LOCUS       NM_001029955            4710 bp    mRNA    linear   PRI 20-FEB-2025
DEFINITION  Homo sapiens DDB1 and CUL4 associated factor 4 like 1 (DCAF4L1),
            mRNA.
ACCESSION   NM_001029955 XM_209607
VERSION     NM_001029955.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4710)
  AUTHORS   Pineau,C., Hikmet,F., Zhang,C., Oksvold,P., Chen,S., Fagerberg,L.,
            Uhlen,M. and Lindskog,C.
  TITLE     Cell Type-Specific Expression of Testis Elevated Genes Based on
            Transcriptomics and Antibody-Based Proteomics
  JOURNAL   J Proteome Res 18 (12), 4215-4230 (2019)
   PUBMED   31429579
REFERENCE   2  (bases 1 to 4710)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   3  (bases 1 to 4710)
  AUTHORS   Kimura,K., Wakamatsu,A., Suzuki,Y., Ota,T., Nishikawa,T.,
            Yamashita,R., Yamamoto,J., Sekine,M., Tsuritani,K., Wakaguri,H.,
            Ishii,S., Sugiyama,T., Saito,K., Isono,Y., Irie,R., Kushida,N.,
            Yoneyama,T., Otsuka,R., Kanda,K., Yokoi,T., Kondo,H., Wagatsuma,M.,
            Murakawa,K., Ishida,S., Ishibashi,T., Takahashi-Fujii,A.,
            Tanase,T., Nagai,K., Kikuchi,H., Nakai,K., Isogai,T. and Sugano,S.
  TITLE     Diversification of transcriptional modulation: large-scale
            identification and characterization of putative alternative
            promoters of human genes
  JOURNAL   Genome Res 16 (1), 55-65 (2006)
   PUBMED   16344560
REFERENCE   4  (bases 1 to 4710)
  AUTHORS   Ota,T., Suzuki,Y., Nishikawa,T., Otsuki,T., Sugiyama,T., Irie,R.,
            Wakamatsu,A., Hayashi,K., Sato,H., Nagai,K., Kimura,K., Makita,H.,
            Sekine,M., Obayashi,M., Nishi,T., Shibahara,T., Tanaka,T.,
            Ishii,S., Yamamoto,J., Saito,K., Kawai,Y., Isono,Y., Nakamura,Y.,
            Nagahari,K., Murakami,K., Yasuda,T., Iwayanagi,T., Wagatsuma,M.,
            Shiratori,A., Sudo,H., Hosoiri,T., Kaku,Y., Kodaira,H., Kondo,H.,
            Sugawara,M., Takahashi,M., Kanda,K., Yokoi,T., Furuya,T.,
            Kikkawa,E., Omura,Y., Abe,K., Kamihara,K., Katsuta,N., Sato,K.,
            Tanikawa,M., Yamazaki,M., Ninomiya,K., Ishibashi,T., Yamashita,H.,
            Murakawa,K., Fujimori,K., Tanai,H., Kimata,M., Watanabe,M.,
            Hiraoka,S., Chiba,Y., Ishida,S., Ono,Y., Takiguchi,S., Watanabe,S.,
            Yosida,M., Hotuta,T., Kusano,J., Kanehori,K., Takahashi-Fujii,A.,
            Hara,H., Tanase,T.O., Nomura,Y., Togiya,S., Komai,F., Hara,R.,
            Takeuchi,K., Arita,M., Imose,N., Musashino,K., Yuuki,H., Oshima,A.,
            Sasaki,N., Aotsuka,S., Yoshikawa,Y., Matsunawa,H., Ichihara,T.,
            Shiohata,N., Sano,S., Moriya,S., Momiyama,H., Satoh,N., Takami,S.,
            Terashima,Y., Suzuki,O., Nakagawa,S., Senoh,A., Mizoguchi,H.,
            Goto,Y., Shimizu,F., Wakebe,H., Hishigaki,H., Watanabe,T.,
            Sugiyama,A., Takemoto,M., Kawakami,B., Yamazaki,M., Watanabe,K.,
            Kumagai,A., Itakura,S., Fukuzumi,Y., Fujimori,Y., Komiyama,M.,
            Tashiro,H., Tanigami,A., Fujiwara,T., Ono,T., Yamada,K., Fujii,Y.,
            Ozaki,K., Hirao,M., Ohmori,Y., Kawabata,A., Hikiji,T., Kobatake,N.,
            Inagaki,H., Ikema,Y., Okamoto,S., Okitani,R., Kawakami,T.,
            Noguchi,S., Itoh,T., Shigeta,K., Senba,T., Matsumura,K.,
            Nakajima,Y., Mizuno,T., Morinaga,M., Sasaki,M., Togashi,T.,
            Oyama,M., Hata,H., Watanabe,M., Komatsu,T., Mizushima-Sugano,J.,
            Satoh,T., Shirai,Y., Takahashi,Y., Nakagawa,K., Okumura,K.,
            Nagase,T., Nomura,N., Kikuchi,H., Masuho,Y., Yamashita,R.,
            Nakai,K., Yada,T., Nakamura,Y., Ohara,O., Isogai,T. and Sugano,S.
  TITLE     Complete sequencing and characterization of 21,243 full-length
            human cDNAs
  JOURNAL   Nat Genet 36 (1), 40-45 (2004)
   PUBMED   14702039
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DB100231.1, AC106052.4, BC104224.1 and BC052943.1.
            
            On Nov 22, 2018 this sequence version replaced NM_001029955.3.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC052943.1, AK122914.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000333141.7/ ENSP00000327796.5
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-345               DB100231.1         61-405
            346-346             AC106052.4         32365-32365
            347-1328            BC104224.1         329-1310
            1329-4618           AC106052.4         33348-36637
            4619-4710           BC052943.1         4621-4712
FEATURES             Location/Qualifiers
     source          1..4710
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
                     /map="4p13"
     gene            1..4710
                     /gene="DCAF4L1"
                     /gene_synonym="WDR21B"
                     /note="DDB1 and CUL4 associated factor 4 like 1"
                     /db_xref="GeneID:285429"
                     /db_xref="HGNC:HGNC:27723"
     exon            1..4710
                     /gene="DCAF4L1"
                     /gene_synonym="WDR21B"
                     /inference="alignment:Splign:2.1.0"
     CDS             38..1228
                     /gene="DCAF4L1"
                     /gene_synonym="WDR21B"
                     /note="WD repeat domain 21B; WD repeat-containing protein
                     21B"
                     /codon_start=1
                     /product="DDB1- and CUL4-associated factor 4-like protein
                     1"
                     /protein_id="NP_001025126.2"
                     /db_xref="CCDS:CCDS33978.1"
                     /db_xref="GeneID:285429"
                     /db_xref="HGNC:HGNC:27723"
                     /translation="MEAERLRLLEEEAKLKKVARMGFNASSMLRKSQLGFLNVTSYSR
                     LANELRVSCMERKKVQIRSLDPSSLASDRFNFILASTNSDQLFVVNQVEVEGSKYGII
                     SLRTLKIPSFHVYVLRNLYVPNRKVKSLCWASLNQLDSHVLLCFEGITDAPSCAVLLP
                     ASRFLSVHTRVNQPGMLCSFQIPEAWSCAWSLNTRAYHCFSAGLSQQVLLTSVATGHQ
                     QSFDTSSDVLAQQFASTAPLLFNGCRSGEIFAIDLRCRNRGKGWRATRLFHDSAVTSV
                     QILQEEQCLMASDMTGKIKLWDLRATKCVRQYEGHVNESAYLPLHVHEEEGIVVAVGQ
                     DCYTRIWSLHDAHLLRTIPSPYSASEDDIPSVAFASRLGGIRGAAPGLLMAVRQDLYC
                     FPFS"
     regulatory      4687..4692
                     /regulatory_class="polyA_signal_sequence"
                     /gene="DCAF4L1"
                     /gene_synonym="WDR21B"
                     /note="hexamer: AATAAA"
     polyA_site      4710
                     /gene="DCAF4L1"
                     /gene_synonym="WDR21B"
                     /note="major polyA site"
ORIGIN      
        1 agaatttcct gtcacgagga acattccgca ggaggaaatg gaggctgaaa ggctgcgact
       61 cctcgaggaa gaggccaagc tgaaaaaggt agccagaatg ggatttaatg catcttccat
      121 gctccgaaaa agccagctag gtttcctcaa cgtcaccagt tactcccgtt tagccaacga
      181 gctgcgtgtg agctgcatgg agcggaaaaa ggtccaaatt cggagcttgg atccctcctc
      241 tttggcgagc gaccgattta acttcattct ggcgagtacc aacagcgacc agctcttcgt
      301 agtgaaccag gtcgaagtcg aaggctccaa gtacggcatc atcagcctgc gaactctgaa
      361 gatcccttcg ttccacgtgt acgtgctcag aaacctctac gtccccaacc ggaaggtgaa
      421 gtccctgtgc tgggcctcgc tgaaccagtt ggactctcac gttctgctgt gcttcgaggg
      481 aatcacagat gctccaagct gtgcagtgct gctcccagcg tcgcggttct taagtgttca
      541 cacaagagtt aaccagcctg gcatgctctg cagtttccag atcccagagg cctggtcctg
      601 tgcgtggtcc ctcaacaccc gggcatatca ctgctttagt gcaggcttgt ctcagcaggt
      661 cctgttgacc agcgtggcga cgggacacca gcagtcattt gataccagca gtgatgtctt
      721 ggcccagcag tttgctagta cggctccttt gctgtttaat ggctgtcgct ccggggagat
      781 ctttgccatt gatctgcgtt gtagaaatcg aggcaagggg tggagggcca ctcgcctgtt
      841 ccatgactca gcagtgacct ctgtgcaaat cctccaagaa gagcaatgcc tgatggcatc
      901 agacatgact ggaaagatca agctgtggga tctgagggcc actaaatgtg taaggcagta
      961 cgaaggtcac gtgaatgagt ccgcctatct gcccctgcat gtgcacgagg aagagggaat
     1021 cgtggtggca gtgggccagg actgctacac gagaatctgg agcctccatg atgcccacct
     1081 gctcagaacc atcccttccc cgtactctgc ctccgaggac gacattccca gcgtggcctt
     1141 cgcttctcgg ctcgggggca tccggggagc agcaccaggg ctgctcatgg ctgtccggca
     1201 ggacctttat tgtttcccct tcagctaatt ctgcaggtgg cagcgcggcc gaatgtggat
     1261 ttgacttaag gaagttaaga gtatcttatt accgtttctg tgagagcatt ttaagagacg
     1321 tgttgtatat agatcgcatc catccggctg ccaggggtaa ggtgttaaga gttttatgtg
     1381 gagacgttct tgtaaagtta tttcagttaa actgtggact taacttgaaa gtccttttca
     1441 taaaaggtac ctgtttcctc ttgttgaatg ccttagaaca gttaaccacc tccccaaccc
     1501 tttttttttt taaataatta agacttttct aaggactgaa gattggcaaa aactaaaata
     1561 aattaaagca gcttctttca ctagtagccc tttagagaag cataatgatg gtactggtaa
     1621 gactgtttga ctaatcatac agggtcccag gcatctgcgc ttgaggaagc cagtgggagt
     1681 ggagacaagg gagaggtaat ttctcagagt ctctacagaa atatttaagg ctggagtttg
     1741 gaatcattaa atttggcctt ctcaaactca atagcagatc tcttaaggtt ctccttttat
     1801 tgttatcatc cataggcatt ggaaggaaag atggatcttt ttaaatacta gaagttttaa
     1861 acagtccttg atgtgctttt gttgaggtac ctttcagaat gtaaggtaca gcagctccgg
     1921 tttctattat ggtgacttga agttcagatt caaggaattg gctttgactt tttgtaatct
     1981 aggagcagca gtttgtgaga gatttattaa aaatgttaaa gagcctgttt ttctactaag
     2041 caaggaagaa aaaaaacgtg taataaggtt agttgctact tcttaatagc caaagcctgg
     2101 aaatgatctg aatttcgaaa atgctaaaat tcgtgatata atcatacaat cggatactgc
     2161 ataataatag aaaataaggc acacttgcta tgtgaaacag tatggaccaa tctcaacatg
     2221 ttgactgaaa ttaggtagaa atgagtacaa actgtatgat tcaattctaa agttcaaaag
     2281 cagtaaaaac ttgtctatgg tgattaaagg tagagtagta cgtacctctg tagaaagaaa
     2341 ggattttttt ttctttttct ttttaggatg tttgagaagt gacatgggga agctttagga
     2401 atgctgagtt ttctttatct tgacacttga tacatacgta attcatatat ctatatgctt
     2461 cacgttttta tagtttactg tatatatgtt attcctcaaa aaataaaaat aagcaattag
     2521 gacactattg tagttaggca agggacaatg atgccttgga cctgcatgtg tgagaagtag
     2581 aaatgatcag aaatgattgc attggaagat cattcgaagg tagtattatt gataaggctt
     2641 gctgatgaga gtaaactaga aagtgaaaga aaaaaggatg gcagcttttt tttttttttt
     2701 tttgagacgg agtctccttc tgtcgcccag gctggagtgc agtggcgcga tctcggctca
     2761 ctgcaagctc tgaggatggc agcttttttg ttaactttag aactggtaga tgatggtgtc
     2821 gtttactaac ctggggagga tgaggagaaa aaactttagg tgaagggaat gatgctgagt
     2881 tttagacatc tactaaacct ccaattggag atacaaagta ttctgcagat caggggtcat
     2941 gtcatggctg gtaatacaaa tttggtgact tcaatacata gaattaaaat agatgggata
     3001 gatgtgcttt atatgacata gatgaggtta atgtaattac atattgatag aagatgagta
     3061 gatcaataga gaagatatgg gagtatggtt aggcacagat ttttggaatc ctttcagtca
     3121 gttttttata ctaacttgat atgtgacatg agaaattgtg taagctttac ttgctgttgt
     3181 ttcttcagtg taaaatgtct tagataataa aactaaatga taaagtagat acagggttaa
     3241 aggatatgta tcttgtccct tttacattgt aagcattcaa aataaaacaa aacaattaat
     3301 gaagaaaaga cattgcaatc attcagtaag aactagctgc agacatatat atgtatatat
     3361 atatatgtct gatactgata tgtcatttat ttggcaattg acaaaaaatg actacataac
     3421 ttgataaact gtttatcctc atttgcaaag aaaacaaatg caaaaaaaaa atcagtaaga
     3481 aaaacacacc taaaagaaag ggaggcaata gtcttgaata ggagaaaaag aggagatcca
     3541 aatggctaat atacatttga aaaggcatcc aacttctttt attgtcaagg aaatgcaaat
     3601 taaaaccaca atgccacacc actttcacta taatggttaa aataaaatag atcaggtgga
     3661 gtgacgttgg gaattaaaag agaagcaaat gttggtgcag ttgtgagcaa atagaacttt
     3721 catatactgt tgagtgtata ctggtacaag cacttggaaa agttagtaat tgctaaagct
     3781 agaagtttgc atactctatg acccagtcat ttcagtccta ggaatatatt aatcagaaat
     3841 gcatacctgt gtccaccata atttgttaat agctccaact ggaaactacc caaatgttca
     3901 ttaatagtag agtggataaa ttgtgggata ttaacacaat ggaatccttt ttgcagtgag
     3961 aatgagcata gcactatgga caaatcctgc aaacataatg ttgaaataaa gatgccaaac
     4021 acaaaagagc acatattgta caactaatgc acataaagtc cctaaacagg caaaatgaat
     4081 ctatgttctt agaagcagga ttaatggtat acttgtaggg cagaagagta gtgaccagaa
     4141 gaagattcta ggaagctagc aatgctggtg tcatgccaga cccctagtga ctccaatagt
     4201 aatggcactg tgtccgagag tccaaagaag atgcgtagac agcgaacaag acttgggttt
     4261 attgggggaa cttatatata gggatggtcc agtggtagta ggctggacag aagaaccact
     4321 actgtttgta aaaagcatgc agtttatata gcattttcat ttagcacact ccacctagca
     4381 acctccattt aacccaaagc aaaggacctt gatcccctat attgcctgtg ttgtaaggga
     4441 tgggctgggg gttcagacgt ccttcataga taaggagtga aactcagggt tagtcgctcc
     4501 tgtttcctta gtttgggatt ctgagcacac attcgtttta gatcacaggg tcgttctcag
     4561 gatatggttg ttactgctgt caggtgcatc ctctctatag cggggtactg gctacacagt
     4621 ttttgttcac tagtgataat tgttagagct atgcccttaa tatatgtctt gtgtgtatta
     4681 tacttcaata aaaagttaaa ttttaaaaaa
//
