LOCUS       NM_139179               2839 bp    mRNA    linear   PRI 05-APR-2024
DEFINITION  Homo sapiens diacylglycerol lipase beta (DAGLB), transcript variant
            1, mRNA.
ACCESSION   NM_139179
VERSION     NM_139179.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2839)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 2839)
  AUTHORS   Shin,M., Ware,T.B. and Hsu,K.L.
  TITLE     DAGL-Beta Functions as a PUFA-Specific Triacylglycerol Lipase in
            Macrophages
  JOURNAL   Cell Chem Biol 27 (3), 314-321 (2020)
   PUBMED   31991095
REFERENCE   3  (bases 1 to 2839)
  AUTHORS   Zhou,D., Zhang,D., Sun,X., Li,Z., Ni,Y., Shan,Z., Li,H., Liu,C.,
            Zhang,S., Liu,Y., Zheng,R., Pan,F., Zhu,Y., Shi,Y. and Lai,M.
  TITLE     A novel variant associated with HDL-C levels by modifying DAGLB
            expression levels: An annotation-based genome-wide association
            study
  JOURNAL   Eur J Hum Genet 26 (6), 838-847 (2018)
   PUBMED   29476167
  REMARK    GeneRIF: we identified a novel HDL-C-associated variant which
            explained nearly half of the expression variance of DAGLB.
REFERENCE   4  (bases 1 to 2839)
  AUTHORS   Singh,P.K., Markwick,R., Lu,L., Howell,F.V., Williams,G. and
            Doherty,P.
  TITLE     Assay and Inhibition of the Purified Catalytic Domain of
            Diacylglycerol Lipase Beta
  JOURNAL   Biochemistry 55 (19), 2713-2721 (2016)
   PUBMED   27115711
  REMARK    GeneRIF: The purified DAGLbeta catalytic domain assay described
            here provides the basis for a relatively clean and convenient assay
            with the potential to be adapted for high-throughput drug discovery
            efforts.
REFERENCE   5  (bases 1 to 2839)
  AUTHORS   Willer,C.J., Schmidt,E.M., Sengupta,S., Peloso,G.M., Gustafsson,S.,
            Kanoni,S., Ganna,A., Chen,J., Buchkovich,M.L., Mora,S.,
            Beckmann,J.S., Bragg-Gresham,J.L., Chang,H.Y., Demirkan,A., Den
            Hertog,H.M., Do,R., Donnelly,L.A., Ehret,G.B., Esko,T.,
            Feitosa,M.F., Ferreira,T., Fischer,K., Fontanillas,P., Fraser,R.M.,
            Freitag,D.F., Gurdasani,D., Heikkila,K., Hypponen,E., Isaacs,A.,
            Jackson,A.U., Johansson,A., Johnson,T., Kaakinen,M., Kettunen,J.,
            Kleber,M.E., Li,X., Luan,J., Lyytikainen,L.P., Magnusson,P.K.E.,
            Mangino,M., Mihailov,E., Montasser,M.E., Muller-Nurasyid,M.,
            Nolte,I.M., O'Connell,J.R., Palmer,C.D., Perola,M., Petersen,A.K.,
            Sanna,S., Saxena,R., Service,S.K., Shah,S., Shungin,D., Sidore,C.,
            Song,C., Strawbridge,R.J., Surakka,I., Tanaka,T., Teslovich,T.M.,
            Thorleifsson,G., Van den Herik,E.G., Voight,B.F., Volcik,K.A.,
            Waite,L.L., Wong,A., Wu,Y., Zhang,W., Absher,D., Asiki,G.,
            Barroso,I., Been,L.F., Bolton,J.L., Bonnycastle,L.L., Brambilla,P.,
            Burnett,M.S., Cesana,G., Dimitriou,M., Doney,A.S.F., Doring,A.,
            Elliott,P., Epstein,S.E., Ingi Eyjolfsson,G., Gigante,B.,
            Goodarzi,M.O., Grallert,H., Gravito,M.L., Groves,C.J., Hallmans,G.,
            Hartikainen,A.L., Hayward,C., Hernandez,D., Hicks,A.A., Holm,H.,
            Hung,Y.J., Illig,T., Jones,M.R., Kaleebu,P., Kastelein,J.J.P.,
            Khaw,K.T., Kim,E., Klopp,N., Komulainen,P., Kumari,M.,
            Langenberg,C., Lehtimaki,T., Lin,S.Y., Lindstrom,J., Loos,R.J.F.,
            Mach,F., McArdle,W.L., Meisinger,C., Mitchell,B.D., Muller,G.,
            Nagaraja,R., Narisu,N., Nieminen,T.V.M., Nsubuga,R.N., Olafsson,I.,
            Ong,K.K., Palotie,A., Papamarkou,T., Pomilla,C., Pouta,A.,
            Rader,D.J., Reilly,M.P., Ridker,P.M., Rivadeneira,F., Rudan,I.,
            Ruokonen,A., Samani,N., Scharnagl,H., Seeley,J., Silander,K.,
            Stancakova,A., Stirrups,K., Swift,A.J., Tiret,L.,
            Uitterlinden,A.G., van Pelt,L.J., Vedantam,S., Wainwright,N.,
            Wijmenga,C., Wild,S.H., Willemsen,G., Wilsgaard,T., Wilson,J.F.,
            Young,E.H., Zhao,J.H., Adair,L.S., Arveiler,D., Assimes,T.L.,
            Bandinelli,S., Bennett,F., Bochud,M., Boehm,B.O., Boomsma,D.I.,
            Borecki,I.B., Bornstein,S.R., Bovet,P., Burnier,M., Campbell,H.,
            Chakravarti,A., Chambers,J.C., Chen,Y.I., Collins,F.S.,
            Cooper,R.S., Danesh,J., Dedoussis,G., de Faire,U., Feranil,A.B.,
            Ferrieres,J., Ferrucci,L., Freimer,N.B., Gieger,C., Groop,L.C.,
            Gudnason,V., Gyllensten,U., Hamsten,A., Harris,T.B., Hingorani,A.,
            Hirschhorn,J.N., Hofman,A., Hovingh,G.K., Hsiung,C.A.,
            Humphries,S.E., Hunt,S.C., Hveem,K., Iribarren,C., Jarvelin,M.R.,
            Jula,A., Kahonen,M., Kaprio,J., Kesaniemi,A., Kivimaki,M.,
            Kooner,J.S., Koudstaal,P.J., Krauss,R.M., Kuh,D., Kuusisto,J.,
            Kyvik,K.O., Laakso,M., Lakka,T.A., Lind,L., Lindgren,C.M.,
            Martin,N.G., Marz,W., McCarthy,M.I., McKenzie,C.A., Meneton,P.,
            Metspalu,A., Moilanen,L., Morris,A.D., Munroe,P.B., Njolstad,I.,
            Pedersen,N.L., Power,C., Pramstaller,P.P., Price,J.F., Psaty,B.M.,
            Quertermous,T., Rauramaa,R., Saleheen,D., Salomaa,V.,
            Sanghera,D.K., Saramies,J., Schwarz,P.E.H., Sheu,W.H.,
            Shuldiner,A.R., Siegbahn,A., Spector,T.D., Stefansson,K.,
            Strachan,D.P., Tayo,B.O., Tremoli,E., Tuomilehto,J., Uusitupa,M.,
            van Duijn,C.M., Vollenweider,P., Wallentin,L., Wareham,N.J.,
            Whitfield,J.B., Wolffenbuttel,B.H.R., Ordovas,J.M., Boerwinkle,E.,
            Palmer,C.N.A., Thorsteinsdottir,U., Chasman,D.I., Rotter,J.I.,
            Franks,P.W., Ripatti,S., Cupples,L.A., Sandhu,M.S., Rich,S.S.,
            Boehnke,M., Deloukas,P., Kathiresan,S., Mohlke,K.L., Ingelsson,E.
            and Abecasis,G.R.
  CONSRTM   Global Lipids Genetics Consortium
  TITLE     Discovery and refinement of loci associated with lipid levels
  JOURNAL   Nat Genet 45 (11), 1274-1283 (2013)
   PUBMED   24097068
REFERENCE   6  (bases 1 to 2839)
  AUTHORS   Schroder,B., Wrocklage,C., Pan,C., Jager,R., Kosters,B.,
            Schafer,H., Elsasser,H.P., Mann,M. and Hasilik,A.
  TITLE     Integral and associated lysosomal membrane proteins
  JOURNAL   Traffic 8 (12), 1676-1686 (2007)
   PUBMED   17897319
REFERENCE   7  (bases 1 to 2839)
  AUTHORS   Ma,J., Dempsey,A.A., Stamatiou,D., Marshall,K.W. and Liew,C.C.
  TITLE     Identifying leukocyte gene expression patterns associated with
            plasma lipid levels in human subjects
  JOURNAL   Atherosclerosis 191 (1), 63-72 (2007)
   PUBMED   16806233
REFERENCE   8  (bases 1 to 2839)
  AUTHORS   Girard,A., Sachidanandam,R., Hannon,G.J. and Carmell,M.A.
  TITLE     A germline-specific class of small RNAs binds mammalian Piwi
            proteins
  JOURNAL   Nature 442 (7099), 199-202 (2006)
   PUBMED   16751776
REFERENCE   9  (bases 1 to 2839)
  AUTHORS   Bisogno,T., Howell,F., Williams,G., Minassi,A., Cascio,M.G.,
            Ligresti,A., Matias,I., Schiano-Moriello,A., Paul,P.,
            Williams,E.J., Gangadharan,U., Hobbs,C., Di Marzo,V. and Doherty,P.
  TITLE     Cloning of the first sn1-DAG lipases points to the spatial and
            temporal regulation of endocannabinoid signaling in the brain
  JOURNAL   J Cell Biol 163 (3), 463-468 (2003)
   PUBMED   14610053
  REMARK    GeneRIF: This gene has been functionally characterized as a
            diacylglycerol-lipase (DAGL), referred to as DAGL beta.  These
            enzymes may have a role in the biosynthesis of the endocannabinoid
            2-arachidnoyl glycerol (2-AG).
REFERENCE   10 (bases 1 to 2839)
  AUTHORS   Lanfranchi,G., Muraro,T., Caldara,F., Pacchioni,B., Pallavicini,A.,
            Pandolfo,D., Toppo,S., Trevisan,S., Scarso,S. and Valle,G.
  TITLE     Identification of 4370 expressed sequence tags from a
            3'-end-specific cDNA library of human skeletal muscle by DNA
            sequencing and filter hybridization
  JOURNAL   Genome Res 6 (1), 35-42 (1996)
   PUBMED   8681137
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DC304654.1, AK075128.1 and F17444.2.
            
            On Nov 24, 2018 this sequence version replaced NM_139179.3.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF450090.1, SRR1803613.277166.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000297056.11/ ENSP00000297056.6
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3                 DC304654.1         59-61
            4-2838              AK075128.1         1-2835
            2839-2839           F17444.2           191-191
FEATURES             Location/Qualifiers
     source          1..2839
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
                     /map="7p22.1"
     gene            1..2839
                     /gene="DAGLB"
                     /gene_synonym="DAGLBETA; KCCR13L"
                     /note="diacylglycerol lipase beta"
                     /db_xref="GeneID:221955"
                     /db_xref="HGNC:HGNC:28923"
                     /db_xref="MIM:614016"
     exon            1..207
                     /gene="DAGLB"
                     /gene_synonym="DAGLBETA; KCCR13L"
                     /inference="alignment:Splign:2.1.0"
     CDS             113..2131
                     /gene="DAGLB"
                     /gene_synonym="DAGLBETA; KCCR13L"
                     /EC_number="3.1.1.3"
                     /EC_number="3.1.1.116"
                     /note="isoform 1 is encoded by transcript variant 1;
                     sn1-specific diacylglycerol lipase beta; DGL-beta;
                     DAGL-beta; PUFA-specific triacylglycerol lipase"
                     /codon_start=1
                     /product="diacylglycerol lipase-beta isoform 1"
                     /protein_id="NP_631918.3"
                     /db_xref="CCDS:CCDS5350.1"
                     /db_xref="GeneID:221955"
                     /db_xref="HGNC:HGNC:28923"
                     /db_xref="MIM:614016"
                     /translation="MPGMVLFGRRWAIASDDLVFPGFFELVVRVLWWIGILTLYLMHR
                     GKLDCAGGALLSSYLIVLMILLAVVICTVSAIMCVSMRGTICNPGPRKSMSKLLYIRL
                     ALFFPEMVWASLGAAWVADGVQCDRTVVNGIIATVVVSWIIIAATVVSIIIVFDPLGG
                     KMAPYSSAGPSHLDSHDSSQLLNGLKTAATSVWETRIKLLCCCIGKDDHTRVAFSSTA
                     ELFSTYFSDTDLVPSDIAAGLALLHQQQDNIRNNQEPAQVVCHAPGSSQEADLDAELE
                     NCHHYMQFAAAAYGWPLYIYRNPLTGLCRIGGDCCRSRTTDYDLVGGDQLNCHFGSIL
                     HTTGLQYRDFIHVSFHDKVYELPFLVALDHRKESVVVAVRGTMSLQDVLTDLSAESEV
                     LDVECEVQDRLAHKGISQAARYVYQRLINDGILSQAFSIAPEYRLVIVGHSLGGGAAA
                     LLATMLRAAYPQVRCYAFSPPRGLWSKALQEYSQSFIVSLVLGKDVIPRLSVTNLEDL
                     KRRILRVVAHCNKPKYKILLHGLWYELFGGNPNNLPTELDGGDQEVLTQPLLGEQSLL
                     TRWSPAYSFSSDSPLDSSPKYPPLYPPGRIIHLQEEGASGRFGCCSAAHYSAKWSHEA
                     EFSKILIGPKMLTDHMPDILMRALDSVVSDRAACVSCPAQGVSSVDVA"
     exon            208..359
                     /gene="DAGLB"
                     /gene_synonym="DAGLBETA; KCCR13L"
                     /inference="alignment:Splign:2.1.0"
     exon            360..531
                     /gene="DAGLB"
                     /gene_synonym="DAGLBETA; KCCR13L"
                     /inference="alignment:Splign:2.1.0"
     exon            532..790
                     /gene="DAGLB"
                     /gene_synonym="DAGLBETA; KCCR13L"
                     /inference="alignment:Splign:2.1.0"
     exon            791..913
                     /gene="DAGLB"
                     /gene_synonym="DAGLBETA; KCCR13L"
                     /inference="alignment:Splign:2.1.0"
     exon            914..1041
                     /gene="DAGLB"
                     /gene_synonym="DAGLBETA; KCCR13L"
                     /inference="alignment:Splign:2.1.0"
     exon            1042..1168
                     /gene="DAGLB"
                     /gene_synonym="DAGLBETA; KCCR13L"
                     /inference="alignment:Splign:2.1.0"
     exon            1169..1252
                     /gene="DAGLB"
                     /gene_synonym="DAGLBETA; KCCR13L"
                     /inference="alignment:Splign:2.1.0"
     exon            1253..1330
                     /gene="DAGLB"
                     /gene_synonym="DAGLBETA; KCCR13L"
                     /inference="alignment:Splign:2.1.0"
     exon            1331..1411
                     /gene="DAGLB"
                     /gene_synonym="DAGLBETA; KCCR13L"
                     /inference="alignment:Splign:2.1.0"
     exon            1412..1539
                     /gene="DAGLB"
                     /gene_synonym="DAGLBETA; KCCR13L"
                     /inference="alignment:Splign:2.1.0"
     exon            1540..1608
                     /gene="DAGLB"
                     /gene_synonym="DAGLBETA; KCCR13L"
                     /inference="alignment:Splign:2.1.0"
     exon            1609..1681
                     /gene="DAGLB"
                     /gene_synonym="DAGLBETA; KCCR13L"
                     /inference="alignment:Splign:2.1.0"
     exon            1682..1932
                     /gene="DAGLB"
                     /gene_synonym="DAGLBETA; KCCR13L"
                     /inference="alignment:Splign:2.1.0"
     exon            1933..2839
                     /gene="DAGLB"
                     /gene_synonym="DAGLBETA; KCCR13L"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2819..2824
                     /regulatory_class="polyA_signal_sequence"
                     /gene="DAGLB"
                     /gene_synonym="DAGLBETA; KCCR13L"
                     /note="hexamer: AATAAA"
     polyA_site      2839
                     /gene="DAGLB"
                     /gene_synonym="DAGLBETA; KCCR13L"
                     /note="major polyA site"
ORIGIN      
        1 gcgtttgcgc ttgagcgccg ataatttggt ggcggcgtcc ggagggtgct ggtttgttct
       61 cggtgaacgg cgcgcggggt ctctcctgag tgcgagctac gggaccttcg ccatgccggg
      121 gatggtactc ttcggccggc gctgggccat cgccagcgac gacttggtct tcccagggtt
      181 cttcgagctg gtcgtgcgag tgctgtggtg gattggcatt ctgacgttgt atctcatgca
      241 cagaggaaag ctggactgtg ctggtggagc cttgctcagc agttacttga tcgtcctcat
      301 gattctcctg gcagttgtca tatgtactgt gtcagccatc atgtgtgtca gcatgagagg
      361 aacgatttgt aaccctggac cgcggaagtc tatgtctaag ctgctttaca tccgcctggc
      421 gctgtttttt ccagagatgg tctgggcctc tctgggggct gcctgggtgg cagatggtgt
      481 tcagtgcgac aggacagttg taaacggcat catcgcaacc gtcgtggtca gttggatcat
      541 catcgctgcc acagtggttt ccattatcat tgtctttgac cctcttgggg ggaaaatggc
      601 tccatattcc tctgccggcc ccagccacct ggatagtcat gattcaagcc agttacttaa
      661 tggcctcaag acagcagcta caagcgtgtg ggaaaccaga atcaagctct tgtgctgttg
      721 cattgggaaa gacgaccata ctcgggttgc tttttcgagt acggcagagc ttttctcaac
      781 ctacttttca gacacagatc tggtgcccag cgacattgcg gcgggcctcg ccctgcttca
      841 tcagcaacag gacaatatca ggaacaacca agagcctgcc caggtggtct gccatgcccc
      901 agggagctcc caggaagctg atctggatgc agaattagaa aactgccatc attacatgca
      961 gtttgcagca gcggcctatg ggtggcccct ctacatctac agaaaccccc tcacggggct
     1021 gtgcaggatt ggtggtgact gctgcagaag cagaaccaca gactatgact tggtcggagg
     1081 cgatcagctc aactgtcact tcggctccat cctgcacacc acagggctgc agtacaggga
     1141 cttcatccac gtcagcttcc atgacaaggt ttacgagctg ccgtttttag tggctctgga
     1201 tcacaggaaa gagtctgttg tggtcgctgt gagggggacc atgtctctgc aggatgtcct
     1261 tacggacctg tcagcggaga gtgaggtgct ggacgtggag tgtgaggtgc aggaccgcct
     1321 ggcacacaag ggtatttctc aagctgccag atacgtttac caacgactca tcaacgacgg
     1381 gattttgagc caagccttca gcattgctcc tgagtaccgg ctggtcatag tgggccacag
     1441 cctcgggggc ggggcggccg ccctgctggc caccatgctc agagccgcct acccgcaggt
     1501 caggtgctac gccttctccc caccccgggg gctgtggagc aaagctctgc aggaatattc
     1561 tcagagcttc atcgtgtcac tcgtcctggg gaaggatgtg attcccaggc tcagtgtgac
     1621 caacttggaa gatctgaaga gaagaatctt gcgagtggtc gcgcactgca ataaacccaa
     1681 gtacaagatc ttgctgcacg gtttgtggta cgaactgttt ggaggaaacc ccaacaactt
     1741 gcccacggag ctggacgggg gcgaccagga agtcctgaca cagcctcttc tgggggagca
     1801 gagcctactg acgcgctggt ccccggccta cagcttctcc agcgactccc cactggactc
     1861 ttctcccaag tacccccctc tctaccctcc cggcaggatc atccacctgc aggaggaggg
     1921 cgcctcgggg cggtttggct gctgctctgc tgctcactat agcgccaagt ggtcacacga
     1981 agcggaattc agcaaaatac tcataggtcc gaagatgctc accgaccaca tgccagacat
     2041 cctgatgcgg gccttggaca gcgtggtctc cgacagagcg gcctgcgtct cctgtccagc
     2101 acaaggggtc tccagtgtgg acgtggcctg accagggcca ctggaaactg tcccaggaac
     2161 gatggactca cgcttttgtc cttaaactga cttaccatcc gaggagttcc catgacgcca
     2221 aaacagcgaa tgtccatcaa caggaatcgg atgggaacag aattccatgg tctcaatgac
     2281 ttaagtttat gggaagtcat tgtggccata atggtagcag aagtagtgag cacgctcagg
     2341 tgataggacg actcctgaga cccagcgacc gtggagacag cctcgggaag ccctggcccg
     2401 tggatggatc ccttggctgt ctgaggactg ctccagaagt gcgggaatcc agggcccacc
     2461 cagaagaccg tgaacagttc cttagcctcc cacccccaag gcagctcttt tcatccaact
     2521 cagtttacag gcgtggtttg tttttcaaac tgggcttcct ggatgtacaa atggaactgt
     2581 ggtgagggtg cgggctgggg ttttctcctg ggcgtcacca agggcagccc tgggctctgg
     2641 ctggggatga agacgaaacc cgatcgggaa agtaagtgga gcccccggcc ccgccgagcc
     2701 acagcccccc aactgcctat tcccactgcc cagttgtttg tccacatcag gagttgctga
     2761 ttgaattctt gctactcttc tggctctggg gtcggccagt ggattcagga gttgaaacaa
     2821 taaagcgcgc gtcaccata
//
