LOCUS       NM_032412                790 bp    mRNA    linear   PRI 01-JUN-2024
DEFINITION  Homo sapiens cysteine rich transmembrane module containing 1
            (CYSTM1), mRNA.
ACCESSION   NM_032412
VERSION     NM_032412.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 790)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 790)
  AUTHORS   Venancio,T.M. and Aravind,L.
  TITLE     CYSTM, a novel cysteine-rich transmembrane module with a role in
            stress tolerance across eukaryotes
  JOURNAL   Bioinformatics 26 (2), 149-152 (2010)
   PUBMED   19933165
REFERENCE   3  (bases 1 to 790)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC013643.1 and CA310907.1.
            
            On Nov 22, 2018 this sequence version replaced NM_032412.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK225992.1, SRR1163658.75140.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000261811.6/ ENSP00000261811.4
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-788               BC013643.1         31-818
            789-790             CA310907.1         17-18               c
FEATURES             Location/Qualifiers
     source          1..790
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="5"
                     /map="5q31.3"
     gene            1..790
                     /gene="CYSTM1"
                     /gene_synonym="C5orf32; ORF1-FL49"
                     /note="cysteine rich transmembrane module containing 1"
                     /db_xref="GeneID:84418"
                     /db_xref="HGNC:HGNC:30239"
     exon            1..98
                     /gene="CYSTM1"
                     /gene_synonym="C5orf32; ORF1-FL49"
                     /inference="alignment:Splign:2.1.0"
     exon            99..305
                     /gene="CYSTM1"
                     /gene_synonym="C5orf32; ORF1-FL49"
                     /inference="alignment:Splign:2.1.0"
     CDS             119..412
                     /gene="CYSTM1"
                     /gene_synonym="C5orf32; ORF1-FL49"
                     /note="putative nuclear protein ORF1-FL49; UPF0467 protein
                     C5orf32"
                     /codon_start=1
                     /product="cysteine-rich and transmembrane
                     domain-containing protein 1"
                     /protein_id="NP_115788.1"
                     /db_xref="CCDS:CCDS4221.1"
                     /db_xref="GeneID:84418"
                     /db_xref="HGNC:HGNC:30239"
                     /translation="MNQENPPPYPGPGPTAPYPPYPPQPMGPGPMGGPYPPPQGYPYQ
                     GYPQYGWQGGPQEPPKTTVYVVEDQRRDELGPSTCLTACWTALCCCCLWDMLT"
     exon            306..790
                     /gene="CYSTM1"
                     /gene_synonym="C5orf32; ORF1-FL49"
                     /inference="alignment:Splign:2.1.0"
     regulatory      769..774
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CYSTM1"
                     /gene_synonym="C5orf32; ORF1-FL49"
                     /note="hexamer: AATAAA"
     polyA_site      790
                     /gene="CYSTM1"
                     /gene_synonym="C5orf32; ORF1-FL49"
                     /note="major polyA site"
ORIGIN      
        1 acttgctctg agacaggtgc ggcaagtcta ctgcgggctg gtccgggctc ctcaggttca
       61 gacccgaccg ttatccagtc ggttcgtgga gaggagaggt gcactttaca ggtccccgat
      121 gaaccaagag aaccctccac catatccagg ccctggtcca acggccccat acccacctta
      181 tccaccacaa ccaatgggtc caggacctat ggggggaccc tacccacctc ctcaagggta
      241 cccctaccaa ggatacccac agtacggctg gcagggtgga cctcaggagc ctcctaaaac
      301 cacagtgtat gtggtagaag accaaagaag agatgagcta ggaccatcca cctgcctcac
      361 agcctgctgg acggctctct gttgctgctg tctctgggac atgctcacct gaccagacca
      421 gcccagccgt cctgtcctgc cagctctgct gccacctctg acaggtgtgc ctgcccccat
      481 ctcttctgat tgctgttaac aaatgactag ctttgcacag acacctctac cttcagcact
      541 atgggattct agattaatgg gggttgctac tgtttaattc agtgacttga tctttttaat
      601 gtccaaaatc catttcttat tgatctttaa agatgtgcta aatgactttt ttggccaaag
      661 gcttagttgt gaaaaatata atttttaaat tatacattca aggtagtggc caaatgtaac
      721 acatcaatca tggaatgatt tctctgctaa cagccgcctg tatgtttcaa taaatttgtc
      781 caaagctcaa
//
