LOCUS       NM_001384189            1229 bp    mRNA    linear   PRI 08-APR-2024
DEFINITION  Homo sapiens cortexin domain containing 2 (CTXND2), mRNA.
ACCESSION   NM_001384189 NR_148929 XR_158744 XR_171214
VERSION     NM_001384189.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1229)
  AUTHORS   Macgregor,S., Montgomery,G.W., Liu,J.Z., Zhao,Z.Z., Henders,A.K.,
            Stark,M., Schmid,H., Holland,E.A., Duffy,D.L., Zhang,M.,
            Painter,J.N., Nyholt,D.R., Maskiell,J.A., Jetann,J., Ferguson,M.,
            Cust,A.E., Jenkins,M.A., Whiteman,D.C., Olsson,H., Puig,S.,
            Bianchi-Scarra,G., Hansson,J., Demenais,F., Landi,M.T., Debniak,T.,
            Mackie,R., Azizi,E., Bressac-de Paillerets,B., Goldstein,A.M.,
            Kanetsky,P.A., Gruis,N.A., Elder,D.E., Newton-Bishop,J.A.,
            Bishop,D.T., Iles,M.M., Helsing,P., Amos,C.I., Wei,Q., Wang,L.E.,
            Lee,J.E., Qureshi,A.A., Kefford,R.F., Giles,G.G., Armstrong,B.K.,
            Aitken,J.F., Han,J., Hopper,J.L., Trent,J.M., Brown,K.M.,
            Martin,N.G., Mann,G.J. and Hayward,N.K.
  TITLE     Genome-wide association study identifies a new melanoma
            susceptibility locus at 1q21.3
  JOURNAL   Nat Genet 43 (11), 1114-1118 (2011)
   PUBMED   21983785
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1229)
  AUTHORS   Harrington,J.J., Sherf,B., Rundlett,S., Jackson,P.D., Perry,R.,
            Cain,S., Leventhal,C., Thornton,M., Ramachandran,R.,
            Whittington,J., Lerner,L., Costanzo,D., McElligott,K., Boozer,S.,
            Mays,R., Smith,E., Veloso,N., Klika,A., Hess,J., Cothren,K., Lo,K.,
            Offenbacher,J., Danzig,J. and Ducar,M.
  TITLE     Creation of genome-wide protein expression libraries using random
            activation of gene expression
  JOURNAL   Nat Biotechnol 19 (5), 440-445 (2001)
   PUBMED   11329013
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL355860.12.
            
            On May 21, 2021 this sequence version replaced NM_001384189.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189658.87396.1, HY235980.1
                                           [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000636087.1/ ENSP00000490418.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-178               AL355860.12        87780-87957
            179-1229            AL355860.12        112886-113936
FEATURES             Location/Qualifiers
     source          1..1229
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q21.3"
     gene            1..1229
                     /gene="CTXND2"
                     /note="cortexin domain containing 2"
                     /db_xref="GeneID:100996521"
                     /db_xref="HGNC:HGNC:53440"
     exon            1..178
                     /gene="CTXND2"
                     /inference="alignment:Splign:2.1.0"
     exon            179..1229
                     /gene="CTXND2"
                     /inference="alignment:Splign:2.1.0"
     CDS             252..419
                     /gene="CTXND2"
                     /codon_start=1
                     /product="cortexin domain containing 2"
                     /protein_id="NP_001371118.1"
                     /db_xref="CCDS:CCDS91049.1"
                     /db_xref="GeneID:100996521"
                     /db_xref="HGNC:HGNC:53440"
                     /translation="MEDSSLSSGVDVDKGFAIAFVVLLFLFLIVMIFRCAKLVKNPYK
                     ASSTTTEPSLS"
     regulatory      425..430
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CTXND2"
                     /note="hexamer: AATAAA"
     polyA_site      449
                     /gene="CTXND2"
                     /note="major polyA site"
     regulatory      1205..1210
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CTXND2"
                     /note="hexamer: AATAAA"
     polyA_site      1229
                     /gene="CTXND2"
ORIGIN      
        1 gaactattca tgaagcttct gagttcagcg tgggagtggg gaagggagag agctaccaac
       61 cactctcctt ttgtgggaag aggttgataa aaacagaggc tgccaagaga tgtacttgag
      121 taggaggaga ctgccctggc aacaagtgaa tgtagccttg gatatccgct ctcagaagga
      181 atatgacaaa tctgaagcta tacctgagga attagctgga gctggacaac agtaacgagg
      241 tgcaagtccc catggaagat tcaagcctgt ccagtggtgt tgatgtggac aaaggctttg
      301 ccattgcctt tgttgttctt ctgtttctgt tcctaatagt gatgattttt cggtgtgcca
      361 agctggtgaa gaatccctac aaggccagct ccacaaccac agaaccatct ctgagctgaa
      421 gtataataaa acctggtaga ctcccccaag caagagattt gaaatctgtt atacacactt
      481 tatattattt cacctccctg tttctcagcc ttctcactct tgcattccac agtgagatga
      541 aacacaagcc agtttgtatt gttcctgttc agggaaatgg ctactaaagt gagataaagg
      601 ttgaatttat tggctagaat aaggccatag attttaattc ttcagtgcct aaggtcctta
      661 ggatgagaca gtgggccata attttatgat gtaatgtaac ataatgtcat catgcttggt
      721 aaggtccacc tgaaactaga agctcaccta gaggtggcag acttgaatga tccctttagt
      781 tatgcaaatg taggctcagc agaaaccaaa tgtcctataa gaagagtgta accagattgt
      841 tttagtgtgt gaagttttat aaaatctgct gttcttaagt gggcagaact ctctggtaga
      901 aggggactaa tttgctgtgg gtgaattcct taatctctct catcccaaat ttcctcatct
      961 ataaaataat atgtagaggt ttcagtgagg gccccagaaa agatatatcc gtgtcctaac
     1021 ccctggaatg tgagcttatt tggaaaaatg gtctttgcaa atataattaa gaatctcaag
     1081 ataaattcat cctgaattat ctaggtgaga cttaaatcca atgactcccc tagagattct
     1141 ggtaccccag tatggtctta ctaacacctt gattttggac ttccggcctt cacaactgtg
     1201 aggaaataaa tttctgttgt tttaaggca
//
