LOCUS       NM_206833               1237 bp    mRNA    linear   PRI 09-FEB-2024
DEFINITION  Homo sapiens cortexin 1 (CTXN1), mRNA.
ACCESSION   NM_206833
VERSION     NM_206833.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1237)
  AUTHORS   Coulter,P.M. 2nd, Bautista,E.A., Margulies,J.E. and Watson,J.B.
  TITLE     Identification of cortexin: a novel, neuron-specific, 82-residue
            membrane protein enriched in rodent cerebral cortex
  JOURNAL   J Neurochem 61 (2), 756-759 (1993)
   PUBMED   8336151
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC062702.1, BC024148.2 and AC010336.8.
            
            On Nov 22, 2018 this sequence version replaced NM_206833.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK098834.1, BC062702.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968540, SAMEA1968968
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000318978.6/ ENSP00000313226.3
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-457               BC062702.1         14-470
            458-1191            BC024148.2         180-913
            1192-1229           BC062702.1         1205-1242
            1230-1232           BC024148.2         952-954
            1233-1237           AC010336.8         105702-105706       c
FEATURES             Location/Qualifiers
     source          1..1237
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p13.2"
     gene            1..1237
                     /gene="CTXN1"
                     /gene_synonym="CTXN"
                     /note="cortexin 1"
                     /db_xref="GeneID:404217"
                     /db_xref="HGNC:HGNC:31108"
                     /db_xref="MIM:600135"
     exon            1..169
                     /gene="CTXN1"
                     /gene_synonym="CTXN"
                     /inference="alignment:Splign:2.1.0"
     exon            170..1237
                     /gene="CTXN1"
                     /gene_synonym="CTXN"
                     /inference="alignment:Splign:2.1.0"
     CDS             190..438
                     /gene="CTXN1"
                     /gene_synonym="CTXN"
                     /codon_start=1
                     /product="cortexin-1"
                     /protein_id="NP_996664.1"
                     /db_xref="CCDS:CCDS12191.1"
                     /db_xref="GeneID:404217"
                     /db_xref="HGNC:HGNC:31108"
                     /db_xref="MIM:600135"
                     /translation="MSATWTLSPEPLPPSTGPPVGAGLDAEQRTVFAFVLCLLVVLVL
                     LMVRCVRILLDPYSRMPASSWTDHKEALERGQFDYALV"
     regulatory      1208..1213
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CTXN1"
                     /gene_synonym="CTXN"
                     /note="hexamer: AATAAA"
     polyA_site      1237
                     /gene="CTXN1"
                     /gene_synonym="CTXN"
                     /note="major polyA site"
ORIGIN      
        1 gctgcttgcc tgcctcggtc tccgccgctc caggggcggg tggggtgggc tgagccggag
       61 cccgggccgc cgccgccgcc gccggggaga ggccgaacgc gcagccggcg cgggtccctg
      121 agagagcgcg gccgccgggc ggtcggtccc cgtccgggtc gaagccaggg gcgcgcggcg
      181 atgtgagcca tgagcgcgac gtggacgctg tcgccggagc ccctgccgcc gtcgacgggg
      241 cccccggtgg gcgcgggcct ggacgcggag cagcgcacgg tgttcgcctt cgtgctctgc
      301 ctgctcgtgg tgctggtgct gttgatggtg cgctgcgtgc gcatcctgct cgacccctac
      361 agccgcatgc ccgcctcgtc ctggaccgac cacaaggagg cgctcgagcg cgggcagttc
      421 gactacgcgt tggtgtgagg ggcgcggcgc cccctagccg gccctgcgcc ggggtctcag
      481 agggccggcc cggcgggggg cgccgcgggg ccaggactgc gctcaggatc ccgccccgga
      541 gcccccagcc cgggggagag ggggagggag ttgggagaag cccagcccct ccccctcgag
      601 acccctccca tgtcccttcc tggcctggcc ggagccccac ctcgtgcctt tatccgccct
      661 gtcccttcct ctctgcgcat ctcacccgcc cggctggccc ccacccccga ctctgaatcc
      721 cgggcgggag gaggaccccc gcaccgcccc ctccccagcg tgtaagtggc tctgctattg
      781 tgcgtccctg gaagtgggga cccccttgtc cctcctccct cccctgttgt ctggccgtcg
      841 tcaaccccac cttgactgag tgttgagccc gtccttgggc tctggtccct gcggggcagg
      901 ctctcccggg cccacggggc ggacgctgca taccaatttg ccctgcaccg cctgtcccgg
      961 agacggagcc cgaaggcctg ccatggcggc tgtgtcgagg atgcgtggcg cctgccgtgg
     1021 cgggacagcg tgggcaggct catttctgcc cccaacccgg gccccaggac aggtcagcgc
     1081 gccctgcccc ggtgcccacc gctgcccccc atccgccctc ctgccacttg cccctgaccc
     1141 ccctgccgtg cctcccgcag ccctcccatg ccgttccact cctccctgcc tctgagccga
     1201 acatgataat aaaagctatt attgagcgct tactgca
//
