LOCUS       XM_047424668            6988 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens C-terminal binding protein 2 (CTBP2),
            transcript variant X8, mRNA.
ACCESSION   XM_047424668
VERSION     XM_047424668.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000010.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6988
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="10"
     gene            1..6988
                     /gene="CTBP2"
                     /note="C-terminal binding protein 2; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 2
                     mRNAs, 49 ESTs, 1656 long SRA reads, 10 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 23 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:1488"
                     /db_xref="HGNC:HGNC:2495"
                     /db_xref="MIM:602619"
     CDS             450..1787
                     /gene="CTBP2"
                     /codon_start=1
                     /product="C-terminal-binding protein 2 isoform X1"
                     /protein_id="XP_047280624.1"
                     /db_xref="GeneID:1488"
                     /db_xref="HGNC:HGNC:2495"
                     /db_xref="MIM:602619"
                     /translation="MALVDKHKVKRQRLDRICEGIRPQIMNGPLHPRPLVALLDGRDC
                     TVEMPILKDLATVAFCDAQSTQEIHEKVLNEAVGAMMYHTITLTREDLEKFKALRVIV
                     RIGSGYDNVDIKAAGELGIAVCNIPSAAVEETADSTICHILNLYRRNTWLYQALREGT
                     RVQSVEQIREVASGAARIRGETLGLIGFGRTGQAVAVRAKAFGFSVIFYDPYLQDGIE
                     RSLGVQRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLV
                     DEKALAQALKEGRIRGAALDVHESEPFSFAQGPLKDAPNLICTPHTAWYSEQASLEMR
                     EAAATEIRRAITGRIPESLRNCVNKEFFVTSAPWSVIDQQAIHPELNGATYRYPPGIV
                     GVAPGGLPAAMEGIIPGGIPVTHNLPTVAHPSQAPSPNQPTKHGDNREHPNEQ"
ORIGIN      
        1 agttggctgc agaggacccc acgtttagga ttttataggg aagaggagga atttttcgta
       61 gaaatccccg ctctgcgtgc tcgtggtgga ggctgctggc aatggcctac gtcgtcatac
      121 cgggcttcct tgccctgtcc gggggtttca tcaccttaaa tggttttgaa ccaatgaagg
      181 tgtattccct taaaaagacg gacagcccat cgtgtgaact atagagtttg tggacagatt
      241 tatattggtt aaacctgtag ctgatgagga acagccctga gtgatgtgtg gggtccaagt
      301 tgttgagaag ggccaaggaa acggaagtac tacacagagt gcttcaaggg ttcatagtgg
      361 cgtcatgcac gcagactcct gcaagttccc ctaagttctt agaggactgc tttgcctttt
      421 gatctgagag ttgcaaagtt ccataaagaa tggcccttgt ggataagcac aaagtcaaga
      481 gacagcgatt ggacagaatt tgtgaaggta tccgccccca gatcatgaac ggccccctgc
      541 acccccgccc cctggtggcg ctgctggacg gccgcgactg cactgtggag atgcccatcc
      601 tgaaggacct ggccactgtg gccttctgtg acgcgcagtc gacgcaggaa atccacgaga
      661 aggttctaaa cgaagccgtg ggcgccatga tgtaccacac catcaccctc accagggagg
      721 acctggagaa gttcaaggcc ctgagagtga tcgtgcggat aggcagtggc tatgacaacg
      781 tggacatcaa ggctgccggc gagctcggaa ttgccgtgtg caacatcccg tctgcagccg
      841 tggaagagac agcggactct accatctgcc acatcctcaa cctgtaccgg aggaacacgt
      901 ggctgtacca ggcactgcgg gaaggcacgc gggttcagag cgtggagcag atccgcgagg
      961 tggcctcggg agcggcccgc atccgtgggg agacgctggg cctcattggc tttggtcgca
     1021 cggggcaggc ggttgcagtt cgagccaagg cctttggatt cagcgtcata ttttatgacc
     1081 cctacttgca ggatgggatc gagcggtccc tgggcgtgca gagggtctac accctgcagg
     1141 atttgctgta tcagagcgac tgcgtctcct tgcactgcaa tctcaacgaa cataaccacc
     1201 acctcatcaa tgactttacc ataaagcaga tgaggcaggg agcattcctt gtgaacgcag
     1261 cccgtggcgg cctggtggac gagaaagcct tagcacaagc cctcaaggag ggcaggatac
     1321 gaggggcagc cctcgacgtg catgagtcag agcccttcag ctttgctcag ggtccgttga
     1381 aagatgcccc gaatctcatc tgcactcctc acactgcctg gtacagtgag caggcgtcac
     1441 tggagatgag ggaggcagct gccaccgaga tccgccgagc catcacaggt cgcatcccag
     1501 aaagcttaag aaattgtgtg aacaaggaat tctttgtcac atcagcgcct tggtcagtaa
     1561 tagaccagca agcaattcat cctgagctca atggtgccac atacagatat ccgccaggca
     1621 tcgtgggtgt ggctccagga ggacttcctg cagccatgga agggatcatc cctggaggca
     1681 tcccagtgac tcacaacctc ccgacagtgg cacatccttc ccaagcgccc tctcccaacc
     1741 agcccacaaa acacggggac aatcgagagc accccaacga gcaatagcag agaatgccag
     1801 aaggtaatca ctcagataca cttgggacca agagacagtg aaaaatagat gaactaagag
     1861 aaaaagaatc ggatggtctt tgtaactgat tctggacata tgcatcattg atgttgcagt
     1921 gttgaaacta caagagctag aaaactgaag atgtcgtctg cttacggaag cgctgaaaga
     1981 ctaggatgtg atttattaac gaccaacttc tgttattgtg tgttaagttt ttcatctgtg
     2041 catcaaatca caaaaagaat aaatagagct ttttccttta tcagtccctt gggcacagca
     2101 ggtcctgaac accctgctct acaatgttgc atcaagagtt caaacaacaa aataaaaaat
     2161 attaagagga aatccccatc ctgtgacttg agtcccttaa gtctacaggg gctggtgacc
     2221 tctttttgct aataggaaaa tcacattact acaaaatggg gagaaaactg tttgcctgtg
     2281 gtagacacct gcacgcatag gattgaagac agtacaggct gctgtacaga gaagcgcctc
     2341 tcacatctga actgcatact gagcgggcaa gtcggttgta agttcagtaa aaccctctga
     2401 tgatgcaaaa aaaaaaaaaa aagtattaag tttcacaagc tgtttgtact caaatatatt
     2461 ttctcagttt cagatcctct gctattttat tgagtggaaa gtcttgagct aaaagggttc
     2521 aagaagaata atgttgcatt tccttatgtc tcaggaaaca ctttttatgg taacttgtca
     2581 gattgtctat gaacaaaccc acttttttag acattgataa agtcttcttt tcttcacgtg
     2641 atattttata caagaacact tcagatgtat tagatgtgac tgattttaac aaatcctatt
     2701 agatttgtat caactagtta catgttctat tcatagtctt ttgtgaatca ttgccttttt
     2761 gtttaaaaag atggcctatt ttgagccttt gtataggtac attcctgttt ttgtgacaaa
     2821 agaaaaactt taaaattgtc ccaaacagaa aaataatggc tatcagaagt atgttttgtt
     2881 ttagtgtgag ttaccgttac tgtatttgtt tattgtaaag gtggacattt agcgttcagt
     2941 gcagttttca ataaaaagta attaaaattt gttaagttct gaaattcaag tacatctcac
     3001 taatgtaaat gttctctact tgagatgttt aaggcaattg cattgtcaat tagccaattt
     3061 ccagctcttg ttactacagg gttccataac cagactcaag accgctgaca attaattacc
     3121 tgtgataaca aaaagtttaa ttgaaaaatc aaaacctcac acaagtccat cattatcacg
     3181 tcatgccatc cttaagatgc aatggtgggt tagtgctaaa tcaattcaaa aaaaaacaaa
     3241 gttgctcaac ttttagagtt ctgactttaa tctaccccaa agcaaaatga cctggacctg
     3301 gttcaaggga gggaagtgaa ccttgaaact gttttgccaa taacctaaca aacaaaatga
     3361 tatttacaaa gaagtgttgc aaatagtccc atgagttaag agcttgattt aatggatctt
     3421 ctttttaaat agaattaaac ctttatacta aaagtatttg caagtgtcaa ttaagtccaa
     3481 caattccagg tatgaaactc cctctgagct cttccttata cttcccttcc caattaaaac
     3541 aaaacaagaa aatcatggtg tcttaaagcc tttggcttgc ctggccttgt ctgctcactc
     3601 attttaaggt ggtggcccca tcccaactct accataaaag tgtctattaa cacaagctca
     3661 catggagaga gacggcgctc atagttactg acctattacc ccagggaaca aaaaggtagt
     3721 ttaacgtctt cgtaaccact catcaaagag gcaatgaaat atgcgtgaaa aggaggccaa
     3781 gcgcacacag aatatcttac cttcacgaat atgtgaagaa gtctgggaca cgatgaacct
     3841 aagagtcaaa aacataaaaa ggcaggtctg aatccatggt ccacctgggt tttaattatt
     3901 agatcttggt cgcccaaaca aaaatttata tatatatata taaatttgac cccaaggaag
     3961 aacaagtcaa aacaaaatgc cacgctctgt ttgctctaga aaaagaacca tcaagtccac
     4021 agagtgcagg tatgacttac tctccagagt cagtcattaa tgtctgtcac ctagccacgt
     4081 ataatcatct ttgaaaaagg actatattct atcttgggac aataattatg gctgttttaa
     4141 tagttcaaga gcataatata gcattgattt accaaaattt ttggccttta acagccagtc
     4201 tatgaaaacc atttagagcc ccattcctgt ctgtagccta ggaaatggaa ccatctttaa
     4261 ttctttccca cagggaagaa tgctgcacct atcacactat gtggtcaggg tcactgattg
     4321 ataataaata aataaataat agagcgctca ggggaaacaa cactcaccag accacaacac
     4381 acagtagaag ctaagtgctg agcgtgtact ctggacaacg ctggctgcaa tgcagactgc
     4441 aatggctaca tgcttttccc tctaacaatt ctctttggct ttttcaattg ggagggcaga
     4501 ttttgcttaa caggcaacta gaacaggatc tctgcccact aaaaaattat ccctatacat
     4561 agagaaatta ctacagatgc taagtagtca gaatgctaac attttctaca aacttgatta
     4621 cttattggcc aaaatgaaag caaacagcca atttttaaca acacattcac cacttgaaac
     4681 aaacagcagc atttacatta tatcaaagat tcatttctac agaatcgtac taaaaaatca
     4741 tttttcctgc aagatttagc atgcagcaaa aaatgatctt ttcatcctgg gaacaccttt
     4801 ttactgagtt ttcgggggga aagaactaaa gacatgacag ttttgtgggt atttttctat
     4861 ttttagtatt ctggcagcaa atttgaggtt gtacacattt cattatcaac taaacaaaac
     4921 aagaagcaag caaatacttt aaggttttca cagccttttt catcacaggg aaggaaaaaa
     4981 ctgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtgcgcgcgc gcgcgtgcgt gtgtcgtctt
     5041 tccaaattcc tggccacatc aatagtctag aaagtgctta tcaggacacc aaatatttct
     5101 gtgttcctga gataggtctg aaatttttac ccagtattga atgtatacct gaagtggtca
     5161 aataatactt cttataaaaa agtttttcta cctaagatta tagttttaac tttaaattaa
     5221 agaatggcca caattaacca acatgcaaaa attctcagac taaacactga gaaattcttc
     5281 atacaatgca tttgccacct tattgcattt ttaaaatctt tattctgtag tgaattggta
     5341 ttcccaatct gcctaagcaa aggcatgccc ttctaacaag atttgcttag agcagaggtg
     5401 atagaaggaa gaatccgaag accctctggc atggcaatct gggagcagca cattgttgat
     5461 ggagtccaag tgagcacatt tcacacaatt catttagtga caagtgggct tgctcccttt
     5521 tcatccagga aaaaaactac tcacagacca ctgcccagaa tctggaataa gaaccctcat
     5581 tttaaggtat tcttcccaac aaataaatat ctaaatattg aaagggggca tatcagaaaa
     5641 cttaaagaca caataaccaa aaccaaaacc ctcttcaaaa caagtaagca atgtctgtat
     5701 ttagttcact ctaaaacatt cttagctttt cttgcagttt gttcctaaaa gatttgattg
     5761 ggcacaagag gaacgaaatt attaataaaa taaaagctta tttttgtttt gctgtggata
     5821 atcggtacaa aacgtttcca gatctgagac ttagatggat cttttaaggt gaaagtagaa
     5881 tgccaggttc tactgaaata atatctgaaa ggaacaaaga gccatttgcc atgtgctttt
     5941 tctaagtgcc catgctggaa aaaattttct caataatatg aagatgctgg tacaactttt
     6001 cctattaaac aatgtcttac acaaccacat gcgttacatt tatagacaga tttacaattt
     6061 ggaaggaaaa aaagttctgt cttaataaaa ttagtttttt ttacaaactg tagtccaact
     6121 aaagttctct gtctcctcac gcagcagagg cattatctcc ataaggtgtg tgtggtccag
     6181 gaaaacactt ccccgagcag atcctgccag atttggttca ttccatgatg tcgactctgc
     6241 ttggagcacc acactaactt tagggtcatt acagatctga tgccttggtc ttctgctgtt
     6301 tgattttttt tttcattcat cttcatcatc ctcatcttcc tctccatcag acagggatgt
     6361 acacggccgg atctgtcggt agcggtcaag ccatttttct accatctgag tgaccagggg
     6421 gtgatttcgc cgccgagaac tcttctgcat ggcaaccaga actcccccct ccgtcacaca
     6481 gcagtccagc cactccctga gcagtttttc ttgctgttcc tcattaccta gcttttggag
     6541 gaatatgaag acaaagggaa aatcatacaa cagatcagag acttggtagg aatgtgacat
     6601 ggaaacctac agctggtatg ctaactcatg aaaaggccaa agcaatcaac ttttcacatg
     6661 gttttgacct cttggaagtt ttgtgattaa agtccagttt gctctggtta aatttaaaaa
     6721 gacataaatg ggaaatttct cagaaaaaaa ctaaagagga gcacactaga gggtaatttg
     6781 ttagataaaa taaaaaacaa atgtcctaat aaactgatcc tggcaagcca cagcttcaaa
     6841 cacatgacaa ggtaagttta cttagtcaat tatgtacaag ctgaaattat acaagttacg
     6901 gtctatgaac tttttttctt catgttgtga ttataaacgt tttataatta ctagtatatt
     6961 aaataaaaga ccaatacttt tataagaa
//
