LOCUS       NM_001007551            2627 bp    mRNA    linear   PRI 20-FEB-2025
DEFINITION  Homo sapiens cancer/testis antigen family 45 member A5 (CT45A5),
            transcript variant 1, mRNA.
ACCESSION   NM_001007551 XM_497164
VERSION     NM_001007551.6
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2627)
  AUTHORS   Pineau,C., Hikmet,F., Zhang,C., Oksvold,P., Chen,S., Fagerberg,L.,
            Uhlen,M. and Lindskog,C.
  TITLE     Cell Type-Specific Expression of Testis Elevated Genes Based on
            Transcriptomics and Antibody-Based Proteomics
  JOURNAL   J Proteome Res 18 (12), 4215-4230 (2019)
   PUBMED   31429579
REFERENCE   2  (bases 1 to 2627)
  AUTHORS   Yu,H., Tardivo,L., Tam,S., Weiner,E., Gebreab,F., Fan,C.,
            Svrzikapa,N., Hirozane-Kishikawa,T., Rietman,E., Yang,X.,
            Sahalie,J., Salehi-Ashtiani,K., Hao,T., Cusick,M.E., Hill,D.E.,
            Roth,F.P., Braun,P. and Vidal,M.
  TITLE     Next-generation sequencing to generate interactome datasets
  JOURNAL   Nat Methods 8 (6), 478-480 (2011)
   PUBMED   21516116
REFERENCE   3  (bases 1 to 2627)
  AUTHORS   Chen,Y.T., Scanlan,M.J., Venditti,C.A., Chua,R., Theiler,G.,
            Stevenson,B.J., Iseli,C., Gure,A.O., Vasicek,T., Strausberg,R.L.,
            Jongeneel,C.V., Old,L.J. and Simpson,A.J.
  TITLE     Identification of cancer/testis-antigen genes by massively parallel
            signature sequencing
  JOURNAL   Proc Natl Acad Sci U S A 102 (22), 7940-7945 (2005)
   PUBMED   15905330
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC240441.2.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 9, 2021 this sequence version replaced NM_001007551.5.
            
            Summary: This gene represents one of a cluster of several similar
            genes located on the q arm of chromosome X. The genes in this
            cluster encode members of the cancer/testis (CT) family of
            antigens, and are distinct from other CT antigens. These antigens
            are thought to be novel therapeutic targets for human cancers.
            Alternative splicing results in multiple transcript variants.
            [provided by RefSeq, Apr 2014].
            
            Transcript Variant: This variant (1) represents the shorter
            transcript. Both variants 1 and 2 encode the same protein.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR11853561.29837.1, BC028711.2
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2151119 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000698999.1/ ENSP00000514077.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-267               AC240441.2         50916-51182         c
            268-442             AC240441.2         47240-47414         c
            443-691             AC240441.2         45072-45320         c
            692-785             AC240441.2         44597-44690         c
            786-2627            AC240441.2         41531-43372         c
FEATURES             Location/Qualifiers
     source          1..2627
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xq26.3"
     gene            1..2627
                     /gene="CT45A5"
                     /gene_synonym="CT45-3; CT45-4; CT45-6; CT45.5; CT455;
                     CT45A3; CT45A4; CT45A6; CT45A7"
                     /note="cancer/testis antigen family 45 member A5"
                     /db_xref="GeneID:441521"
                     /db_xref="HGNC:HGNC:33270"
                     /db_xref="MIM:300796"
     exon            1..267
                     /gene="CT45A5"
                     /gene_synonym="CT45-3; CT45-4; CT45-6; CT45.5; CT455;
                     CT45A3; CT45A4; CT45A6; CT45A7"
                     /inference="alignment:Splign:2.1.0"
     exon            268..442
                     /gene="CT45A5"
                     /gene_synonym="CT45-3; CT45-4; CT45-6; CT45.5; CT455;
                     CT45A3; CT45A4; CT45A6; CT45A7"
                     /inference="alignment:Splign:2.1.0"
     CDS             274..843
                     /gene="CT45A5"
                     /gene_synonym="CT45-3; CT45-4; CT45-6; CT45.5; CT455;
                     CT45A3; CT45A4; CT45A6; CT45A7"
                     /note="cancer/testis antigen CT45-5; cancer/testis antigen
                     45-5; cancer/testis antigen 45A5; Cancer/testis antigen
                     family 45 member A6; Cancer/testis antigen 45-6;
                     Cancer/testis antigen 45A6; Cancer/testis antigen family
                     45 member A7; Cancer/testis antigen 45A7; Cancer/testis
                     antigen family 45 member A3; Cancer/testis antigen 45-3;
                     Cancer/testis antigen 45-4; Cancer/testis antigen 45A3;
                     Cancer/testis antigen 45A4; Cancer/testis antigen family
                     45 member A4"
                     /codon_start=1
                     /product="cancer/testis antigen family 45 member A5"
                     /protein_id="NP_001007552.2"
                     /db_xref="CCDS:CCDS35406.1"
                     /db_xref="GeneID:441521"
                     /db_xref="HGNC:HGNC:33270"
                     /db_xref="MIM:300796"
                     /translation="MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGD
                     SLIAGSAMSKEKKLMTGHAIPPSQLDSQIDDFTGFSKDGMMQKPGSNAPVGGNVTSSF
                     SGDDLECRETASSPKSQREINADIKRKLVKELRCVGQKYEKIFEMLEGVQGPTAVRKR
                     FFESIIKEAARCMRRDFVKHLKKKLKRMI"
     exon            443..691
                     /gene="CT45A5"
                     /gene_synonym="CT45-3; CT45-4; CT45-6; CT45.5; CT455;
                     CT45A3; CT45A4; CT45A6; CT45A7"
                     /inference="alignment:Splign:2.1.0"
     exon            692..785
                     /gene="CT45A5"
                     /gene_synonym="CT45-3; CT45-4; CT45-6; CT45.5; CT455;
                     CT45A3; CT45A4; CT45A6; CT45A7"
                     /inference="alignment:Splign:2.1.0"
     exon            786..2627
                     /gene="CT45A5"
                     /gene_synonym="CT45-3; CT45-4; CT45-6; CT45.5; CT455;
                     CT45A3; CT45A4; CT45A6; CT45A7"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agcactctgg cgcccccaac aggttcccag tgttcggctg gggcaggcac gctgtggctg
       61 gctacttccc ttcctcccat cccccttggg ccaaacggga tcggtgcttc tggtgagacg
      121 cctccccatg cacatcactc ccaggtgccc tagggggcac atttcccaca actcccagag
      181 ggcaggtttc tagaaagtgc caccagtggg gaggcgccac aacttcactg ccattttgtg
      241 aggtgccgcc gtctctcctc cagcaaggaa acaatgaccg ataaaacaga gaaggtggct
      301 gtagatcctg aaactgtgtt taaacgtccc agggaatgtg acagtccttc gtatcagaaa
      361 aggcagagga tggccctgtt ggcaaggaaa caaggagcag gagacagcct tattgcaggc
      421 tctgccatgt ccaaagaaaa gaagcttatg acaggacatg ctattccacc cagccaattg
      481 gattctcaga ttgatgactt cactggtttc agcaaagatg ggatgatgca gaaacctggt
      541 agcaatgcac ctgtgggagg aaacgttacc agcagtttct ctggagatga cctagaatgc
      601 agagaaacag cctcctctcc caaaagccaa cgagaaatta atgctgatat aaaacgtaaa
      661 ttagtgaagg aactccgatg cgttggacaa aaatatgaaa aaatcttcga aatgcttgaa
      721 ggagtgcaag gacctactgc agtcaggaag cgattttttg aatccatcat caaggaagca
      781 gcaagatgta tgagacgaga ctttgttaag caccttaaga agaaactgaa acgtatgatt
      841 tgagaatact tgtccctgga ggattatcac accccaaatg cataatctcg ttaatgattg
      901 aggagagaaa aggatcagat tgctgttttc tacaatggag caggatattg ctgaagtctc
      961 ctggcatatg ttaccgaatc aactggcctt ccagaggcta agaaatttct gttagtaaaa
     1021 gatgttcttt ttcccaaagc gttttatttg aaaggataac ttgtgttttg gttattttgt
     1081 attcccacct gtgctggtag atattattaa cccattaggt aaatactatt acagtcgtgg
     1141 tttctgcagc agctcacact gatgtagctg gcgtttataa ctaccttctt tcgctacccg
     1201 tttcgcattc cctttgccct gagatagcat gtcagttggt catgatgctt ggcctggcag
     1261 gatgactcaa accttcatta cggaagagtc tgaaccatta gatatcctgc ctggatgggg
     1321 ttgctgtgat tttccattaa ctctaatcga aaaacacagg aggactaaga agctctctag
     1381 acatatcaca catactcttc cttagcccct cgtgtggtgg gaacccgatc tcaatgttga
     1441 aatctgtatc atcagccttc aacgaaaagg cagaactaat gggagatttt aatgtgtgtg
     1501 tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgttggta gggggtatat atacatgcac
     1561 acacacactt tctaatctcc cattatacat ataatacaca ttacacatat tatatataca
     1621 cccccatata tatatatgta tgcgtgtgtg ggggggtata tccaatatat ataataaagg
     1681 tagttcctag ataggattgg tctgatacaa taatttggag ctgcagtagc agtccctgta
     1741 aggctgttgt ttccagatac gacttgaacg ttctatgctt tttatttttt ttaaagacag
     1801 aatcttgctc tgttgcccag gctagagtgc ggtgacacga tcacaagtca ctgccacctc
     1861 gacctcaccc cagttcaagc gatccttgtg cttcagcctt cgaagtagct gggattacag
     1921 gtgcaccaca ggtgccatca cgctgcaatt tttgtatttt tagtggagat ggggttttgc
     1981 catgttgtcc aggctggtct cgaaacctgg cctcaagtga tctgcccatc tcagcctccc
     2041 aaggttctag gattacaggc atgagccact gcacccagcc cattctatgc tttttttaaa
     2101 aaaattaatt cattcaatta ttcaacaaat attaattgtg ccaggtactt ttttttatta
     2161 tactttaagg tttagggtac atgtgcacaa cgtgcaggtt tgttacatat gtatacatgt
     2221 gccatttttg tgtgctgcac ccattaactc atcatttaac attaggtata tctcctaatg
     2281 ctatccctcc cccctcccca caccccacaa caggacccag tgtgtgatgt tccccttcct
     2341 gtgtccatgt gttctcattg ttcagttccc acctatgagg gagaacatgc ggtgtttggt
     2401 tttttgtcct tgcgatagtt tgctgagaat gatggtttcc agcttcatcc atgtccctac
     2461 aaaggacatg aactcatcat ttttcatggc tgcatagtat tccatggtgt atatgtgcca
     2521 cgttttctta atccagtcta tcattgttgg acatttgggt tggttccaag tctttgctat
     2581 tgtgaatagt gccacaataa acatacgtgt gcatgtgtct ttatagc
//
