LOCUS       NM_001370148             968 bp    mRNA    linear   PRI 20-FEB-2025
DEFINITION  Homo sapiens cancer/testis antigen family 45 member A3 (CT45A3),
            transcript variant 1, mRNA.
ACCESSION   NM_001370148 XM_011531340
VERSION     NM_001370148.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 968)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 968)
  AUTHORS   Pineau,C., Hikmet,F., Zhang,C., Oksvold,P., Chen,S., Fagerberg,L.,
            Uhlen,M. and Lindskog,C.
  TITLE     Cell Type-Specific Expression of Testis Elevated Genes Based on
            Transcriptomics and Antibody-Based Proteomics
  JOURNAL   J Proteome Res 18 (12), 4215-4230 (2019)
   PUBMED   31429579
REFERENCE   3  (bases 1 to 968)
  AUTHORS   Fragoza,R., Das,J., Wierbowski,S.D., Liang,J., Tran,T.N., Liang,S.,
            Beltran,J.F., Rivera-Erick,C.A., Ye,K., Wang,T.Y., Yao,L., Mort,M.,
            Stenson,P.D., Cooper,D.N., Wei,X., Keinan,A., Schimenti,J.C.,
            Clark,A.G. and Yu,H.
  TITLE     Extensive disruption of protein interactions by genetic variants
            across the allele frequency spectrum in human populations
  JOURNAL   Nat Commun 10 (1), 4141 (2019)
   PUBMED   31515488
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 968)
  AUTHORS   Chen,Y.T., Scanlan,M.J., Venditti,C.A., Chua,R., Theiler,G.,
            Stevenson,B.J., Iseli,C., Gure,A.O., Vasicek,T., Strausberg,R.L.,
            Jongeneel,C.V., Old,L.J. and Simpson,A.J.
  TITLE     Identification of cancer/testis-antigen genes by massively parallel
            signature sequencing
  JOURNAL   Proc Natl Acad Sci U S A 102 (22), 7940-7945 (2005)
   PUBMED   15905330
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            HY033723.1, AY743711.1, AI581344.1 and AC240441.2.
            
            On Aug 29, 2019 this sequence version replaced NM_001370148.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BU942323.1, SRR5189667.223224.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2151119 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000598716.3/ ENSP00000471571.2
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-482               HY033723.1         2-483
            483-853             AY743711.1         638-1008
            854-966             AI581344.1         1-113               c
            967-968             AC240441.2         25723-25724         c
FEATURES             Location/Qualifiers
     source          1..968
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xq26.3"
     gene            1..968
                     /gene="CT45A3"
                     /gene_synonym="CT45-3; CT45-4; CT45.3; CT45.4; CT45A4"
                     /note="cancer/testis antigen family 45 member A3"
                     /db_xref="GeneID:441519"
                     /db_xref="HGNC:HGNC:33268"
                     /db_xref="MIM:300794"
     exon            1..84
                     /gene="CT45A3"
                     /gene_synonym="CT45-3; CT45-4; CT45.3; CT45.4; CT45A4"
                     /inference="alignment:Splign:2.1.0"
     exon            85..259
                     /gene="CT45A3"
                     /gene_synonym="CT45-3; CT45-4; CT45.3; CT45.4; CT45A4"
                     /inference="alignment:Splign:2.1.0"
     CDS             91..660
                     /gene="CT45A3"
                     /gene_synonym="CT45-3; CT45-4; CT45.3; CT45.4; CT45A4"
                     /note="cancer/testis antigen CT45-3; cancer/testis antigen
                     45-3; cancer/testis antigen 45A3; cancer/testis antigen
                     45-4; cancer/testis antigen 45A4; cancer/testis antigen
                     family 45 member A4"
                     /codon_start=1
                     /product="cancer/testis antigen family 45 member A3"
                     /protein_id="NP_001357077.1"
                     /db_xref="CCDS:CCDS76030.1"
                     /db_xref="GeneID:441519"
                     /db_xref="HGNC:HGNC:33268"
                     /db_xref="MIM:300794"
                     /translation="MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGD
                     SLIAGSAMSKEKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSF
                     SGDDLECRETASSPKSQREINADIKRKLVKELRCVGQKYEKIFEMLEGVQGPTAVRKR
                     FFESIIKEAARCMRRDFVKHLKKKLKRMI"
     exon            260..508
                     /gene="CT45A3"
                     /gene_synonym="CT45-3; CT45-4; CT45.3; CT45.4; CT45A4"
                     /inference="alignment:Splign:2.1.0"
     exon            509..602
                     /gene="CT45A3"
                     /gene_synonym="CT45-3; CT45-4; CT45.3; CT45.4; CT45A4"
                     /inference="alignment:Splign:2.1.0"
     exon            603..968
                     /gene="CT45A3"
                     /gene_synonym="CT45-3; CT45-4; CT45.3; CT45.4; CT45A4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agtgttcggc tggggcaggc acgctgtggc tggctacttc ccttcctccc atcccccttg
       61 ggccaaacgg gatcggtgct tctggaaaca atgaccgata aaacagagaa ggtggctgta
      121 gatcctgaaa ctgtgtttaa acgtcccagg gaatgtgaca gtccttcgta tcagaaaagg
      181 cagaggatgg ccctgttggc aaggaaacaa ggagcaggag acagccttat tgcaggctct
      241 gccatgtcca aagaaaagaa gcttatgaca ggacatgcta ttccacccag ccaattggat
      301 tctcagattg atgacttcac tggtttcagc aaagatagga tgatgcagaa acctggtagc
      361 aatgcacctg tgggaggaaa cgttaccagc agtttctctg gagatgacct agaatgcaga
      421 gaaacagcct cctctcccaa aagccaacga gaaattaatg ctgatataaa acgtaaatta
      481 gtgaaggaac tccgatgcgt tggacaaaaa tatgaaaaaa tcttcgaaat gcttgaagga
      541 gtgcaaggac ctactgcagt caggaagcga ttttttgaat ccatcatcaa ggaagcagca
      601 agatgtatga gacgagactt tgttaagcac cttaagaaga aactgaaacg tatgatttga
      661 gaatacttgt ccctggagga ttatcacacc ccaaatgcat aatctcgtta atgattgagg
      721 agagaaaagg atcagattgc tgttttctac aatggagcag gatattgctg aagtctcctg
      781 gcatatgtta ccgaatcaaa tagccttcca gaggctaaga aatttctgtt agtaaaagat
      841 gttctttttc ccaaagcatt ttatttgaaa ggataacttg tgttttggtt attttgtatt
      901 cccacctgtg ctggtagata ttattaaccc attaggtaaa tactattaca gtcgtggttt
      961 ctgcagca
//
