LOCUS       NM_001291529             869 bp    mRNA    linear   PRI 20-FEB-2025
DEFINITION  Homo sapiens cancer/testis antigen family 45 member A10 (CT45A10),
            transcript variant 3, mRNA.
ACCESSION   NM_001291529 XM_006724794 XM_006726850
VERSION     NM_001291529.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 869)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 869)
  AUTHORS   Pineau,C., Hikmet,F., Zhang,C., Oksvold,P., Chen,S., Fagerberg,L.,
            Uhlen,M. and Lindskog,C.
  TITLE     Cell Type-Specific Expression of Testis Elevated Genes Based on
            Transcriptomics and Antibody-Based Proteomics
  JOURNAL   J Proteome Res 18 (12), 4215-4230 (2019)
   PUBMED   31429579
REFERENCE   3  (bases 1 to 869)
  AUTHORS   Chen,Y.T., Scanlan,M.J., Venditti,C.A., Chua,R., Theiler,G.,
            Stevenson,B.J., Iseli,C., Gure,A.O., Vasicek,T., Strausberg,R.L.,
            Jongeneel,C.V., Old,L.J. and Simpson,A.J.
  TITLE     Identification of cancer/testis-antigen genes by massively parallel
            signature sequencing
  JOURNAL   Proc Natl Acad Sci U S A 102 (22), 7940-7945 (2005)
   PUBMED   15905330
REFERENCE   4  (bases 1 to 869)
  AUTHORS   Ross,M.T., Grafham,D.V., Coffey,A.J., Scherer,S., McLay,K.,
            Muzny,D., Platzer,M., Howell,G.R., Burrows,C., Bird,C.P.,
            Frankish,A., Lovell,F.L., Howe,K.L., Ashurst,J.L., Fulton,R.S.,
            Sudbrak,R., Wen,G., Jones,M.C., Hurles,M.E., Andrews,T.D.,
            Scott,C.E., Searle,S., Ramser,J., Whittaker,A., Deadman,R.,
            Carter,N.P., Hunt,S.E., Chen,R., Cree,A., Gunaratne,P., Havlak,P.,
            Hodgson,A., Metzker,M.L., Richards,S., Scott,G., Steffen,D.,
            Sodergren,E., Wheeler,D.A., Worley,K.C., Ainscough,R.,
            Ambrose,K.D., Ansari-Lari,M.A., Aradhya,S., Ashwell,R.I.,
            Babbage,A.K., Bagguley,C.L., Ballabio,A., Banerjee,R., Barker,G.E.,
            Barlow,K.F., Barrett,I.P., Bates,K.N., Beare,D.M., Beasley,H.,
            Beasley,O., Beck,A., Bethel,G., Blechschmidt,K., Brady,N.,
            Bray-Allen,S., Bridgeman,A.M., Brown,A.J., Brown,M.J., Bonnin,D.,
            Bruford,E.A., Buhay,C., Burch,P., Burford,D., Burgess,J.,
            Burrill,W., Burton,J., Bye,J.M., Carder,C., Carrel,L., Chako,J.,
            Chapman,J.C., Chavez,D., Chen,E., Chen,G., Chen,Y., Chen,Z.,
            Chinault,C., Ciccodicola,A., Clark,S.Y., Clarke,G., Clee,C.M.,
            Clegg,S., Clerc-Blankenburg,K., Clifford,K., Cobley,V., Cole,C.G.,
            Conquer,J.S., Corby,N., Connor,R.E., David,R., Davies,J., Davis,C.,
            Davis,J., Delgado,O., Deshazo,D., Dhami,P., Ding,Y., Dinh,H.,
            Dodsworth,S., Draper,H., Dugan-Rocha,S., Dunham,A., Dunn,M.,
            Durbin,K.J., Dutta,I., Eades,T., Ellwood,M., Emery-Cohen,A.,
            Errington,H., Evans,K.L., Faulkner,L., Francis,F., Frankland,J.,
            Fraser,A.E., Galgoczy,P., Gilbert,J., Gill,R., Glockner,G.,
            Gregory,S.G., Gribble,S., Griffiths,C., Grocock,R., Gu,Y.,
            Gwilliam,R., Hamilton,C., Hart,E.A., Hawes,A., Heath,P.D.,
            Heitmann,K., Hennig,S., Hernandez,J., Hinzmann,B., Ho,S., Hoffs,M.,
            Howden,P.J., Huckle,E.J., Hume,J., Hunt,P.J., Hunt,A.R.,
            Isherwood,J., Jacob,L., Johnson,D., Jones,S., de Jong,P.J.,
            Joseph,S.S., Keenan,S., Kelly,S., Kershaw,J.K., Khan,Z.,
            Kioschis,P., Klages,S., Knights,A.J., Kosiura,A., Kovar-Smith,C.,
            Laird,G.K., Langford,C., Lawlor,S., Leversha,M., Lewis,L., Liu,W.,
            Lloyd,C., Lloyd,D.M., Loulseged,H., Loveland,J.E., Lovell,J.D.,
            Lozado,R., Lu,J., Lyne,R., Ma,J., Maheshwari,M., Matthews,L.H.,
            McDowall,J., McLaren,S., McMurray,A., Meidl,P., Meitinger,T.,
            Milne,S., Miner,G., Mistry,S.L., Morgan,M., Morris,S., Muller,I.,
            Mullikin,J.C., Nguyen,N., Nordsiek,G., Nyakatura,G., O'Dell,C.N.,
            Okwuonu,G., Palmer,S., Pandian,R., Parker,D., Parrish,J.,
            Pasternak,S., Patel,D., Pearce,A.V., Pearson,D.M., Pelan,S.E.,
            Perez,L., Porter,K.M., Ramsey,Y., Reichwald,K., Rhodes,S.,
            Ridler,K.A., Schlessinger,D., Schueler,M.G., Sehra,H.K.,
            Shaw-Smith,C., Shen,H., Sheridan,E.M., Shownkeen,R., Skuce,C.D.,
            Smith,M.L., Sotheran,E.C., Steingruber,H.E., Steward,C.A.,
            Storey,R., Swann,R.M., Swarbreck,D., Tabor,P.E., Taudien,S.,
            Taylor,T., Teague,B., Thomas,K., Thorpe,A., Timms,K., Tracey,A.,
            Trevanion,S., Tromans,A.C., d'Urso,M., Verduzco,D., Villasana,D.,
            Waldron,L., Wall,M., Wang,Q., Warren,J., Warry,G.L., Wei,X.,
            West,A., Whitehead,S.L., Whiteley,M.N., Wilkinson,J.E.,
            Willey,D.L., Williams,G., Williams,L., Williamson,A.,
            Williamson,H., Wilming,L., Woodmansey,R.L., Wray,P.W., Yen,J.,
            Zhang,J., Zhou,J., Zoghbi,H., Zorilla,S., Buck,D., Reinhardt,R.,
            Poustka,A., Rosenthal,A., Lehrach,H., Meindl,A., Minx,P.J.,
            Hillier,L.W., Willard,H.F., Wilson,R.K., Waterston,R.H., Rice,C.M.,
            Vaudin,M., Coulson,A., Nelson,D.L., Weinstock,G., Sulston,J.E.,
            Durbin,R., Hubbard,T., Gibbs,R.A., Beck,S., Rogers,J. and
            Bentley,D.R.
  TITLE     The DNA sequence of the human X chromosome
  JOURNAL   Nature 434 (7031), 325-337 (2005)
   PUBMED   15772651
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC240441.2.
            
            On Jul 10, 2020 this sequence version replaced NM_001291529.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC070138.1, SRR14038196.707912.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1968968,
                                           SAMEA2148093 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000682849.1/ ENSP00000507965.1
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-100               AC240441.2         159024-159123       c
            101-275             AC240441.2         150855-151029       c
            276-524             AC240441.2         148687-148935       c
            525-618             AC240441.2         148215-148308       c
            619-869             AC240441.2         146744-146994       c
FEATURES             Location/Qualifiers
     source          1..869
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xq26.3"
     gene            1..869
                     /gene="CT45A10"
                     /gene_synonym="CT45-5; CT45A5"
                     /note="cancer/testis antigen family 45 member A10"
                     /db_xref="GeneID:102723631"
                     /db_xref="HGNC:HGNC:51263"
     exon            1..100
                     /gene="CT45A10"
                     /gene_synonym="CT45-5; CT45A5"
                     /inference="alignment:Splign:2.1.0"
     exon            101..275
                     /gene="CT45A10"
                     /gene_synonym="CT45-5; CT45A5"
                     /inference="alignment:Splign:2.1.0"
     CDS             107..676
                     /gene="CT45A10"
                     /gene_synonym="CT45-5; CT45A5"
                     /note="cancer/testis antigen family 45 member A-like;
                     Cancer/testis antigen 45A10; Cancer/testis antigen family
                     45 member A5; Cancer/testis antigen 45-5; Cancer/testis
                     antigen 45A5"
                     /codon_start=1
                     /product="cancer/testis antigen family 45 member A10"
                     /protein_id="NP_001278458.1"
                     /db_xref="CCDS:CCDS76035.1"
                     /db_xref="GeneID:102723631"
                     /db_xref="HGNC:HGNC:51263"
                     /translation="MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGD
                     SLIAGSAMSKEKKLMTGHAIPPSQLDSQIDDFTGFSKDGMMQKPGSNAPVGGNVTSNF
                     SGDDLECRGIASSPKSQQEINADIKCQVVKEIRCLGRKYEKIFEMLEGVQGPTAVRKR
                     FFESIIKEAARCMRRDFVKHLKKKLKRMI"
     exon            276..524
                     /gene="CT45A10"
                     /gene_synonym="CT45-5; CT45A5"
                     /inference="alignment:Splign:2.1.0"
     exon            525..618
                     /gene="CT45A10"
                     /gene_synonym="CT45-5; CT45A5"
                     /inference="alignment:Splign:2.1.0"
     exon            619..869
                     /gene="CT45A10"
                     /gene_synonym="CT45-5; CT45A5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ataactccca aacggcaagt ttctacaaag ttacaacagt ggggaggcgc cacaacttca
       61 ctgccatttt gtgaggtgct gccgcccctc ctccggcaag gaaacaatga ccgataaaac
      121 agagaaggtg gctgtagatc ctgaaactgt gtttaaacgt cccagggaat gtgacagtcc
      181 ttcgtatcag aaaaggcaga ggatggccct gttggcaagg aaacaaggag caggagacag
      241 ccttattgca ggctctgcca tgtccaaaga aaagaagctt atgacaggac atgctattcc
      301 acccagccaa ttggattctc agattgatga cttcactggt ttcagcaaag atgggatgat
      361 gcagaaacct ggtagcaatg cacctgtggg aggaaacgtt accagcaatt tctctggaga
      421 tgacctagaa tgcagaggaa tagcctcctc tcccaaaagc caacaagaaa ttaatgctga
      481 tataaaatgt caagtagtga aggaaatccg atgccttgga cgaaaatatg aaaaaatctt
      541 cgaaatgctt gaaggagtgc aaggacctac tgcagtcagg aaacgatttt ttgaatccat
      601 catcaaggaa gcagcaagat gtatgagacg agactttgtt aagcacctta agaagaaact
      661 gaaacgtatg atttgagaat acttgtccct ggaggattat cacaccccaa atgcataatc
      721 tcgttaatga ttgaggagag aaaaggatca gattgctgtt ttctacaatg gagcaggata
      781 ttgctgaagt ctcctggcat atgttaccga atcaactggc cttccagagg ctaagaaatt
      841 tctgttagta aaagatgttc tttttccca
//
