LOCUS       NM_001172173           11737 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens cysteine and serine rich nuclear protein 3 (CSRNP3),
            transcript variant 1, mRNA.
ACCESSION   NM_001172173
VERSION     NM_001172173.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 11737)
  AUTHORS   Deelen,J., Beekman,M., Uh,H.W., Broer,L., Ayers,K.L., Tan,Q.,
            Kamatani,Y., Bennet,A.M., Tamm,R., Trompet,S., Guethbjartsson,D.F.,
            Flachsbart,F., Rose,G., Viktorin,A., Fischer,K., Nygaard,M.,
            Cordell,H.J., Crocco,P., van den Akker,E.B., Bohringer,S.,
            Helmer,Q., Nelson,C.P., Saunders,G.I., Alver,M.,
            Andersen-Ranberg,K., Breen,M.E., van der Breggen,R., Caliebe,A.,
            Capri,M., Cevenini,E., Collerton,J.C., Dato,S., Davies,K., Ford,I.,
            Gampe,J., Garagnani,P., de Geus,E.J., Harrow,J., van Heemst,D.,
            Heijmans,B.T., Heinsen,F.A., Hottenga,J.J., Hofman,A., Jeune,B.,
            Jonsson,P.V., Lathrop,M., Lechner,D., Martin-Ruiz,C.,
            Mcnerlan,S.E., Mihailov,E., Montesanto,A., Mooijaart,S.P.,
            Murphy,A., Nohr,E.A., Paternoster,L., Postmus,I., Rivadeneira,F.,
            Ross,O.A., Salvioli,S., Sattar,N., Schreiber,S., Stefansson,H.,
            Stott,D.J., Tiemeier,H., Uitterlinden,A.G., Westendorp,R.G.,
            Willemsen,G., Samani,N.J., Galan,P., Sorensen,T.I., Boomsma,D.I.,
            Jukema,J.W., Rea,I.M., Passarino,G., de Craen,A.J., Christensen,K.,
            Nebel,A., Stefansson,K., Metspalu,A., Magnusson,P., Blanche,H.,
            Christiansen,L., Kirkwood,T.B., van Duijn,C.M., Franceschi,C.,
            Houwing-Duistermaat,J.J. and Slagboom,P.E.
  TITLE     Genome-wide association meta-analysis of human longevity identifies
            a novel locus conferring survival beyond 90 years of age
  JOURNAL   Hum Mol Genet 23 (16), 4420-4432 (2014)
   PUBMED   24688116
REFERENCE   2  (bases 1 to 11737)
  AUTHORS   Dick,D.M., Meyers,J., Aliev,F., Nurnberger,J. Jr., Kramer,J.,
            Kuperman,S., Porjesz,B., Tischfield,J., Edenberg,H.J., Foroud,T.,
            Schuckit,M., Goate,A., Hesselbrock,V. and Bierut,L.
  TITLE     Evidence for genes on chromosome 2 contributing to alcohol
            dependence with conduct disorder and suicide attempts
  JOURNAL   Am J Med Genet B Neuropsychiatr Genet 153B (6), 1179-1188 (2010)
   PUBMED   20468071
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   3  (bases 1 to 11737)
  AUTHORS   Maestrini,E., Pagnamenta,A.T., Lamb,J.A., Bacchelli,E., Sykes,N.H.,
            Sousa,I., Toma,C., Barnby,G., Butler,H., Winchester,L.,
            Scerri,T.S., Minopoli,F., Reichert,J., Cai,G., Buxbaum,J.D.,
            Korvatska,O., Schellenberg,G.D., Dawson,G., de Bildt,A.,
            Minderaa,R.B., Mulder,E.J., Morris,A.P., Bailey,A.J. and
            Monaco,A.P.
  CONSRTM   IMGSAC
  TITLE     High-density SNP association study and copy number variation
            analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L-DOCK4
            gene region in autism susceptibility
  JOURNAL   Mol Psychiatry 15 (9), 954-968 (2010)
   PUBMED   19401682
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   4  (bases 1 to 11737)
  AUTHORS   Hendrickx,A., Beullens,M., Ceulemans,H., Den Abt,T., Van Eynde,A.,
            Nicolaescu,E., Lesage,B. and Bollen,M.
  TITLE     Docking motif-guided mapping of the interactome of protein
            phosphatase-1
  JOURNAL   Chem Biol 16 (4), 365-371 (2009)
   PUBMED   19389623
REFERENCE   5  (bases 1 to 11737)
  AUTHORS   Gingras,S., Pelletier,S., Boyd,K. and Ihle,J.N.
  TITLE     Characterization of a family of novel cysteine- serine-rich nuclear
            proteins (CSRNP)
  JOURNAL   PLoS One 2 (8), e808 (2007)
   PUBMED   17726538
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK126129.1, AK056655.1 and AC019140.5.
            
            On Nov 23, 2018 this sequence version replaced NM_001172173.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Both variants 1 and 2 encode the same protein.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660805.41981.1,
                                           SRR1803617.49415.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968540, SAMEA1968832
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000651982.1/ ENSP00000498841.1
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-510               AK126129.1         50-559
            511-1737            AK056655.1         458-1684
            1738-11737          AC019140.5         145404-155403
FEATURES             Location/Qualifiers
     source          1..11737
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q24.3"
     gene            1..11737
                     /gene="CSRNP3"
                     /gene_synonym="FAM130A2; MBU1; PPP1R73; TAIP-2; TAIP2"
                     /note="cysteine and serine rich nuclear protein 3"
                     /db_xref="GeneID:80034"
                     /db_xref="HGNC:HGNC:30729"
                     /db_xref="MIM:620405"
     exon            1..43
                     /gene="CSRNP3"
                     /gene_synonym="FAM130A2; MBU1; PPP1R73; TAIP-2; TAIP2"
                     /inference="alignment:Splign:2.1.0"
     exon            44..213
                     /gene="CSRNP3"
                     /gene_synonym="FAM130A2; MBU1; PPP1R73; TAIP-2; TAIP2"
                     /inference="alignment:Splign:2.1.0"
     exon            214..302
                     /gene="CSRNP3"
                     /gene_synonym="FAM130A2; MBU1; PPP1R73; TAIP-2; TAIP2"
                     /inference="alignment:Splign:2.1.0"
     exon            303..473
                     /gene="CSRNP3"
                     /gene_synonym="FAM130A2; MBU1; PPP1R73; TAIP-2; TAIP2"
                     /inference="alignment:Splign:2.1.0"
     CDS             326..2083
                     /gene="CSRNP3"
                     /gene_synonym="FAM130A2; MBU1; PPP1R73; TAIP-2; TAIP2"
                     /note="family with sequence similarity 130, member A2;
                     TGF-beta induced apoptosis protein 2; protein phosphatase
                     1, regulatory subunit 73"
                     /codon_start=1
                     /product="cysteine/serine-rich nuclear protein 3"
                     /protein_id="NP_001165644.1"
                     /db_xref="CCDS:CCDS2225.1"
                     /db_xref="GeneID:80034"
                     /db_xref="HGNC:HGNC:30729"
                     /db_xref="MIM:620405"
                     /translation="MSGILKRKFEEVDGSSPCSSVRESDDEVSSSESADSGDSVNPST
                     SSHFTPSSILKREKRLRTKNVHFSCVTVYYFTRRQGFTSVPSQGGSTLGMSSRHNSVR
                     QYTLGEFAREQERLHREMLREHLREEKLNSLKLKMTKNGTVESEEASTLTLDDISDDD
                     IDLDNTEVDEYFFLQPLPTKKRRALLRASGVKKIDVEEKHELRAIRLSREDCGCDCRV
                     FCDPDTCTCSLAGIKCQVDRMSFPCGCTKEGCSNTAGRIEFNPIRVRTHFLHTIMKLE
                     LEKNREQQIPTLNGCHSEISAHSSSMGPVAHSVEYSIADSFEIETEPQAAVLHLQSAE
                     ELDCQGEEEEEEEDGSSFCSGVTDSSTQSLAPSESDEEEEEEEEEEEEEDDDDDKGDG
                     FVEGLGTHAEVVPLPSVLCYSDGTAVHESHAKNASFYANSSTLYYQIDSHIPGTPNQI
                     SENYSERDTVKNGTLSLVPYTMTPEQFVDYARQAEEAYGASHYPAANPSVIVCCSSSE
                     NDSGVPCNSLYPEHRSNHPQVEFHSYLKGPSQEGFVSALNGDSHISEHPAENSLSLAE
                     KSILHEECIKSPVVETVPV"
     exon            474..733
                     /gene="CSRNP3"
                     /gene_synonym="FAM130A2; MBU1; PPP1R73; TAIP-2; TAIP2"
                     /inference="alignment:Splign:2.1.0"
     exon            734..1030
                     /gene="CSRNP3"
                     /gene_synonym="FAM130A2; MBU1; PPP1R73; TAIP-2; TAIP2"
                     /inference="alignment:Splign:2.1.0"
     exon            1031..11737
                     /gene="CSRNP3"
                     /gene_synonym="FAM130A2; MBU1; PPP1R73; TAIP-2; TAIP2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      11714..11719
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CSRNP3"
                     /gene_synonym="FAM130A2; MBU1; PPP1R73; TAIP-2; TAIP2"
                     /note="hexamer: AGTAAA"
     polyA_site      11737
                     /gene="CSRNP3"
                     /gene_synonym="FAM130A2; MBU1; PPP1R73; TAIP-2; TAIP2"
                     /note="major polyA site"
ORIGIN      
        1 agtgtgttct gacggagccg aagtacagaa accatattta caggtacatg tgacagcgtt
       61 gcagctatga gtggaatttt aaaggggaag tttgaagaag tcaacggctc ctcaccctgc
      121 tcttcagtgc aggaatcaga tgatgaagtt ttcagctgtg acagtactga gagtgttgat
      181 agtgtcaatc gttcagtttt aatgatttta ccagaaaaaa tgaggaaata tcaacagact
      241 gaaaatatgt tttcagaggc atagaatctt caggaaaata ctggagttcc tgagatctca
      301 aggtacatgt gacagcactg cagcgatgag tggaatttta aagaggaagt ttgaagaagt
      361 tgacggctcc tcaccctgct cctctgtgag ggaatcagat gatgaagttt ccagcagtga
      421 aagtgctgac agtggggaca gtgtcaatcc atccacttct agtcatttta ccccttcctc
      481 cattctcaaa agggagaaac gactgaggac aaagaatgta cattttagtt gtgtcaccgt
      541 gtactacttc accaggaggc aaggcttcac aagtgtgccc agtcaagggg gaagcaccct
      601 ggggatgtcc agccgccata acagcgtgcg ccagtacact cttggcgagt ttgcaaggga
      661 gcaggagagg ctccaccggg agatgttgag agaacacctt agggaggaaa agctgaactc
      721 cttaaaacta aagatgacta agaatggcac agtagaatca gaagaagcca gcactcttac
      781 actggatgac atttctgatg atgacattga cctggacaac acagaggtag atgagtactt
      841 cttcctacaa cctttgccaa caaaaaaacg aagagctctg ctgcgtgcct ctggagtgaa
      901 aaagattgac gtggaagaaa agcacgaact ccgagccatc cgcctctcac gagaggactg
      961 tggctgtgac tgccgagtgt tctgtgatcc agacacgtgc acctgcagcc tggctggcat
     1021 taagtgccag gtggatcgta tgtctttccc atgcggctgc actaaagaag gatgtagtaa
     1081 cacagcaggt agaattgaat ttaatcctat ccgtgttcgg actcactttt tgcacacaat
     1141 aatgaaactt gaactggaga aaaaccgaga gcagcaaatc cccacgctga atggctgcca
     1201 cagtgagata agtgctcaca gtagttctat gggccctgtc gctcactccg tagaatattc
     1261 aatcgcagac agttttgaga ttgaaactga gccccaggct gcagtgctgc acctgcagtc
     1321 ggctgaagaa ttagattgcc aaggagagga ggaggaagaa gaggaggatg ggagcagctt
     1381 ttgcagcgga gtcacagatt ctagcacgca aagcttggca cctagtgagt cagacgagga
     1441 ggaggaggaa gaagaagagg aagaggagga ggaggatgac gatgatgaca aaggagatgg
     1501 cttcgtggaa ggtttgggca cccatgccga agttgtccct cttccttcag ttctttgtta
     1561 ttctgatggc accgccgttc acgaaagcca tgcaaagaat gcttcttttt atgccaactc
     1621 ttcaactctg tattaccaaa tagatagcca cattccagga actccaaatc agatctctga
     1681 gaactattct gaaagagaca ctgtcaaaaa tggtaccctt tcgctggtgc cttacaccat
     1741 gaccccggag caattcgttg actatgcccg acaagcagaa gaggcctatg gtgcctccca
     1801 ctacccagct gccaacccct ctgtaatcgt ttgctgctcc tcttccgaaa atgatagcgg
     1861 tgtgccctgc aatagtttat atcctgaaca caggtccaat caccctcaag tggaatttca
     1921 ctcatacttg aaaggcccct cccaagaagg gtttgtctct gcattgaatg gtgacagtca
     1981 catttcagag catcctgctg aaaattcttt gagccttgca gaaaagagca tattgcatga
     2041 agagtgcatc aaatcacccg tggttgagac agtccctgtt tagtagctta aattattcta
     2101 ggaccaactc ttctcttatt taaggcactg tatttaattg gatttcctgg gctcatcatt
     2161 gtttaaactg aagaccaaga aaacttggac ggtggttaat cttccagact gtattttgtt
     2221 ttttcctttc tagccacatg actgtggcat tgcacaaata cagtctctgt agggatttta
     2281 aaagatttca gactgttttg atagaaaaag ctaaatttta aaatgcatat ctcacagttg
     2341 cctacctgtc aaactgtgtg aaacctgcca atctgtgtag atcagagctc caaattttgg
     2401 attatcgggc ctgtgcaaga ttgttaacta aggctgggaa ataataagat ttagagtcct
     2461 aattttcaat atatctgaag ataatgatga ctttttaatg taaaagtaat tattgtaaga
     2521 aaaagattta attgttccat gtgtatttta tttatggtag tttagaagac atgttttgat
     2581 gaaaatgaac agccgcatgt tcattcaagc tgaagatgca tagctagttc cacagagcat
     2641 gcccacatgg attgcatctg gaatccattc acatttttat gatcatgact gatcagattt
     2701 gcaaattctt aagggtgaaa taggcctatt tttgctattt tggacaaata aatgattcta
     2761 tatgtgcagg tccttacaca gttttctcta aagttaagag ttaggacaat cctctgggga
     2821 gagtctagtt cactgccctc cctcagctga ctccagagat ggaggtagaa ggaattgcct
     2881 ttctttttta aacagcatca tcttgattct tagcttggac agcaccttta agctctaccc
     2941 cctacatcaa aatgcacttt agtgcccctt cacggtacct cgtgtggggt ggggactgag
     3001 aactctttga gatgaaaaaa tttaaaaaaa aattaaaaag atctttaact attataaggt
     3061 tcatataatt aatatagagg aatcatccaa tgatacttat gaagggaaaa tgacctattt
     3121 tccttcacca ctctgaggac ctaactcagt aaatgcagag gaggctgagg aaacatggaa
     3181 gagacacgac ctcagcaacc agccttttct ccagcgtgat caatccatct ctacaaaatc
     3241 agtgtataat gagatttcca cttagtgact agctgattga aggggggcct ctacccaaat
     3301 actcaactag gcctttcttt tctgaagcat tttgatttgt cttgcctggg acaactagca
     3361 gaacagtcca gaatgcattg catactttct aattacctca cattctctta ttaaagagaa
     3421 cagatagaaa taaaacatgc actccccacc tttagattac ctgcacttgg ttcgtcggag
     3481 gacttctagg atcccgtttc cctgtaaatt aatttaggta actaaatagt gtaattctgc
     3541 cttttttttt ccaatgcaat atgactatgc taaacctgtt tcatattttt gaccttctat
     3601 tgttatatca cttcacatgt tttataacta tttgaaatgc ggacatgact tgctattcag
     3661 tgactgcatc gctacttatt ttttatgtct tttagacttg ggtgtttaga attatggata
     3721 taaatatatt gtagatctca atttctaaaa aaaatatttt atttaattga acttaaaaat
     3781 gcttgatcta gagaaagtcc tccagtggaa aagtttctac taaactttgt tttggggaaa
     3841 aaatgtttac ttggcagctc ttccactgtg cagttggttt ctgccccttc tcttcccccc
     3901 tacattgggc caaatttata actcttaata ttaacattaa aagagctttg ggtttgtctt
     3961 tatgtaggtt gcagtaatga gagcagggtt gttccttttg aatgattggc cctttgggct
     4021 aatcagaatg aggatttgtt gaaatctcaa atatacatat atatatatat atatatatat
     4081 atatatatat acacacacac acacacatac acatatatat acacatatat gtatgtgtgt
     4141 gtgtgtgtgt gtgtgtgtgt atatatatat atcccatgtt gtctgcaaag tgacagtttt
     4201 tagtgcttaa tctccaaaat tttcccccta ctgatacaat ctaaagagca caggcccaaa
     4261 gagaaaatga caagaggcta ttgttccttc attcaagcac atgaaaggat catgtgtact
     4321 gtatttgctg gaccattaca agctcttgaa ggatctgctt gtgaagtact ctgaggttat
     4381 tcttggaaca cagagtgtgg gagagtgggg aagagccagc tccagcctga gcaaagctga
     4441 agggtagaat gacagtccag tttctgaaaa gagatatttt aattttagtt cagctttatt
     4501 ttcctaagac gatatgaagc ctactttttt atttttggct aggtctttgt tttctagctt
     4561 tgtttccaaa aggatgctta agaaaacaga gtttttttcc cctatccatt tatctagggt
     4621 agaaagtcac tgccctgtga gaagaattac ccttccaatc atgacagctt ctattccaac
     4681 ttttcatata cctgactaac ctgtaaacat atcccacaaa ccacatacac aggctaccta
     4741 ttaaaactct cccatatacc taacacatac acatgcacac acatacaaaa tatatacata
     4801 tcacacactt agagaatgac agatttcagg caatggccaa tagtcagtat tgagtttttc
     4861 taaccccaga atctggttgg gctttatgat ctaaaaaaat gtggtttaga aaagaggata
     4921 attggtagag ctgtagtttg aaaatatcag gtcaaagttg caaacatact tatgatggaa
     4981 tcatttcatt tttagttcct ttcccagaaa agctgagaga gcacactgtt ccagctgact
     5041 tttttttcca ttaatagccg ttctattcaa caaagagctg cccacatgcc aggaaagtgc
     5101 tacagtcctt ctaagctttt aaaaatgggg atcaagctac atgcagccag ttggaatact
     5161 taagatcttt atgccaagac acaataacct gacctgcagc tgttgtattg cctccatagt
     5221 atatctagcc aaactgtagt ctttgacaca caacttttta gtcattcact atcaattgca
     5281 aagcttcatg ctccagccct ggctattcta gtaccagtcc tataccttta aatgggactt
     5341 aattcccagt tataatcctg gccgaattga tttgaaagtc aagtggctga agcagcttgc
     5401 atctcctttg tcattcccaa tttcctttgg gagaagtcaa tgaaagagat ttacttaagt
     5461 ttttcctcct tatctcttga tcattaatta ttaagacatg ggtaaaattc atttgtctca
     5521 tgtcttttgg ttgattgaat aatatagtta ctttttgaaa gcccatcatt tctttgtgat
     5581 aaaaccattt tctcaatgtg acagccacat gtaaaatgtg aaactaatgt ttcttagtat
     5641 gtttaaaatc ttcacaatca tatatggccc tgcaatactc cctgaattcc ttccctccaa
     5701 aaaaaaacta tgagttgcaa aaacactagt tacgaattaa tcaagaagca aagagagtat
     5761 gttaagtggc tatgttcttt aaaattttac attctaatag atgacttcta ggcaaaattt
     5821 tggtatgatt accattaaac aggaaaacat accatgattt actttctata acttgctaat
     5881 cactgtttct tttatttcaa tttttgatat tgttgcacaa gtttatgact ctttggtctt
     5941 tatattcaaa atttattaag tatcaattct ttctttcaac aaatatgtac tgaacacatg
     6001 ctgtgttaga acaactgtct tgggtagtaa aaagagggga acactacaaa ttataatgga
     6061 taatattaat gaagggtggc atgaaataat caagctttct caaatcctct taatatgtga
     6121 ttttatcaag tgacattaga aaaactgaca tcagttcttg tctaattata tgtgagctgc
     6181 aactaaaaga tgcttccttt acctaaatta tagaactcac tggatcgccc ttcatctctc
     6241 tccctccatc tgaaatgtat gaattaaatc aggactcagc taggactgaa tcaaatgaaa
     6301 aagaaatttt cgattaattg cttcttcaat gttagaccta tataagtgat gctaaattta
     6361 caccagcaaa ctcctatcag acagtttcaa ggaggatttg actcatgcat aacccaggaa
     6421 acatttcagg aaacttttaa gacaacagtg tggaacacaa tcactcttac ttctatttat
     6481 aaaaagccta tcaaaacagc aaaatcctgt tgcaaattcc aaagacatca ctttgcagca
     6541 ggtggaaaac agagaggttg ttagactcca tcactttcag ctggagttac aaaccatcaa
     6601 attagcaggt ggaaaattta tattctcaga agccaacagg agactgcctt tttaaaaggt
     6661 gtcatgaagc cttctatttc tccaaacaac tcaatatttc tctttaaaat ggcatctctg
     6721 ttccttattc tcttgatgac agtttgcagt gccattatag ccagtgtatt aaataccagg
     6781 ctttaatggg aagcaccttt gtgctttcaa aggcaagact tgtctgtaat tttaaattag
     6841 aactgttggt tgtattctta ccacaaccaa aacccaaagt ttaaaggctt gattactcta
     6901 tattaggtct aatatgaatt ttcaccttct gattgcatta ctttttctga aatctgctaa
     6961 ctagtgctgg aataacaaaa atgcctaagc caaaatgctg tagctctgca ccaacagcac
     7021 agctcatcag atgttttcta tagtagtaaa gaatttgatt gacttaattg aatatcagca
     7081 attttaatac ccactagaat tatggaagta tcagagtgga agtgaggacg caataaaagc
     7141 ttaataagtg gtggtgtctt ctaggaatta tgaaaaaaaa agctcagcag agctaagcca
     7201 gatcttatta catcataaag actagagtta caaatggcag ccccaaacct agaaggggca
     7261 gttacaatgt ggacaccctt tcagcccagt tggtgctcac atctgctgac caacattcat
     7321 atcaattaca tttttacagt ctgtaagtca tttgatgctt tagaaaataa aaacacacac
     7381 ctacagcatt ctaaagaaac tattttgtta aaaaatttaa acacatttta tattaaaata
     7441 agtgatcaat gactttcatg attgtcaaaa gtaaaaagtg cagacattta aaaaagctct
     7501 tctttcacat tttacctacc aaatctagat attcaacgtg agtccttaaa acagtcactt
     7561 ctaaatttta ttttgactcc tttcttggct ttttcaaact ggaccatgag acccccttcc
     7621 taaacaatgc agttgttttg ttttattctt tttttccaga aattcaagct gaaacatttg
     7681 atatgacctg tgttttacct ggtgatcagt tctcaggcta gtctaagtct gtgctgtctt
     7741 ggcatgcctt gggtttccta tcctgagagt ggtaatgcca gtagaatgat gggaaccagg
     7801 agagtgaata cgaccagatt caaagcctaa aacaatatgt ttcagtttac ttttatatgt
     7861 agatttttta aatattcaca tctagcctgg aattttagta aatacagata cttgttgtat
     7921 ccatgggaaa tgaggtcatt tcaaagatgt aagtcacgtt ggtgactact ttcttttact
     7981 tgtgataaat atatcactat acagggtaat tgcttttata aatttgatcc tttgcattgg
     8041 cttataattc aagaaatgtc aacttcactg tgtcacttta tgtcatctct cataaaagtt
     8101 tctggcagga ctaaagtttc aaaggaatgt gatagaattt attttggata acatttgtat
     8161 tcagcatgct aatgatgtaa ctcctctctt tatcattacc acggtgatag ttaagttcat
     8221 tcgttaactc attttagtga catgtgaggc catttaaata tttttaagat aatgtatatt
     8281 gattagaaag ggttagaagg agacaaattt atggtagaaa ttagccttgc cattgtctaa
     8341 gttaatttat gtgacctgat tgaacagttt tagttgtaac tttagagtag cttctttgtt
     8401 agaggatctc tttcctttct cttttggttt tctcccaata tttttatctg tcttgggatt
     8461 atcttaaaag gtatttatta atgagtattt ggaagaaaat tgacctagaa aatgtctctt
     8521 ttaaatttat ctaggtactt gtatcaccag agaccttcat caagtcctac tgccacactg
     8581 gataaggcca ctacccccga cccttcttgt cagggacatg gcttcctaat aatggttttg
     8641 ctgttgtctc tacatagggg acctatggaa aaggagtttg aaatttctac ctttgtagta
     8701 cattgtatcc aattttgttt tgctcctcct tttcatgtgg tcaccaagct tttttcctta
     8761 gccattaaaa aagccacccc tctttaaaac aaatttaaag atctatatac atttttgcaa
     8821 ctttatttaa taaaaaagag aagaaaaaat aaaatctaaa tctcaattac cctaaagtgg
     8881 aaaaacctaa gtatctaacc taggaacttg ttgcctggtg gtggttgttg ttgttgttgt
     8941 tttttaattt atttagtgtt gatccttgag ttatttaatg gtatccaaat gatatctgaa
     9001 agtgattgat tttaagatgt aatagttggc aaagtcattt catttgtgtc tcaaacaaat
     9061 aaagcccact gccatgggtt accatctgaa ccctgattca ttaggcacta gtcatgccaa
     9121 atggggatct cagaatagtt taatcttttc aaagatactc acaatggcca actgtgtgtg
     9181 aatactggaa agtttgagat tcttctatat tcttcaaatt tatggtcctg agactaggag
     9241 ggatctccag aggtcatatg gctcatcgat ctaccaccag ggaagactgt cacttaggca
     9301 tgcccaacag gagagatcgc catctattct taacatctct agggaaggca gtttccttgg
     9361 caacacaatt cagctctctt aggttttctc acaataagaa aatatcttgg ccagtctttg
     9421 agggttaggc acctggcaac agttgtggtg atttgggcca ttgtactagg ggattcaagg
     9481 gaagttgggt ttccccctac atttggtgat tattacatta atatatgatc attccataag
     9541 tctcctaaga aatcagattt ttaaagaaag acacggattc agagacaatg gtctgtaaca
     9601 tgaccaactt ttgacaaata tggctgtact aggttttcat ttttgctgtt gttgttgttt
     9661 gtttttgtga ttgctcttat gtcggtaggt aatgtcagga aaagtgactg tttcagatcc
     9721 ccagtacaaa catcagaact aggatcaaat gacttgactt ttaagctgtt ccattttcta
     9781 agaagttaca attacaaaaa gtaagcattt tctacattct tacttctaag taatgacctt
     9841 ctcattaatc tttccttggc ttaaaatgac aaataagaat ccaaagtttt tccactcctc
     9901 ctgtgggaga taggaatagt tgtgaagagt ctgatggaat aaaatgactc cagagattta
     9961 cacagccacc atttgatccc agcctttgtc cttgtgttat ttaaacaatg gcttcctgct
    10021 ttctcagggg tcaggaaaat gatttaaaaa tttgtcttct tgacaaggcc tgaaaacgaa
    10081 gggaggtgtc gtggagaaat ggtgattttt ctggttacat cacttgattc aagcactccc
    10141 tggagctttc aaagcctttt ttatctgctc agagttgaca cccaactcag agtcagaact
    10201 caccagaaga tgaggaacac ccccgaaatc aatgtttcct ttctccatgg gatttttttc
    10261 aatcttggta cagctgcata tctcccaaac tcggatgctc ttgtgaaatg acagccacat
    10321 cagtgtggtt actccccaca aataacacta gggggaaatg acctttttta tttaaaaaaa
    10381 aaaaaaaggc taatgctata gaatgatcat gtaaagaatg ttgaataaaa tttggcccat
    10441 gttttaattg actctaggca cctctattga aataagtctg aggcatagtt tgtgaaacat
    10501 gtttcaaaag tgtttgatgt ataataaatg ctagaaattt acagtacaga aatagtaaaa
    10561 aaataaaata aaaataaacc tgtagattac agctctgttc ctaagaacct cagcctttat
    10621 tgtgtcttag taaagttgat ctgctttatt tttagtttat tgaatttctg gtgtactagc
    10681 ctcttaagat agaactttta atacatatgt actggttaat gcctgtttac gcagaaaatg
    10741 gcactttgtt ctttcagtgt gtttccctca gtgtcacagg gtatatcaat ttgatagatc
    10801 atttgacatt tgtcaaaaat acgtttccca ttttaaaaat atgtataatt ggttgcatag
    10861 acatatgtca ctttttgcag tgtcttcatc ttgatcatag ttttagacat caactatgtc
    10921 tcactttcca actgccatag aaatttggta catttgcaaa ttctggtgga atctagtgag
    10981 ctgaatgtat tggtagatca aatgatccaa aggacttggg tgttatcctt cagtctgtgt
    11041 tgaaccattc agatattggg aatggtcctt acacaaggga agtcttttga gaatatttgt
    11101 tctcttattt tttgtttgtt tgttgctggc aaaaaaaaaa gtaactttaa aaactcagaa
    11161 aagccactga actgtatttt gtgaccttat gattagtttt atctttcaac tgatttttat
    11221 tgttactttt actcaatatc aacagtactt caatagatat ttattagtta tgttcaatct
    11281 aatgacttaa aacagttgaa aaggaggaaa atcaactcca gtccacacat acagtcatgt
    11341 tacattaaga tgtcatgttg tatgtcacac agtttctaga ttgatttctc ttgtgtataa
    11401 gttataacat caaaaatgcc aaagggtata taaaataagc tacaataata ttcaacagaa
    11461 cttaacctgg accttatgtt gtaataattt attcatatta gctgtagtct tctgtattta
    11521 tattttcagt atttattatg aatgacatgg aaattcgtgt atttattgtg gctttttatt
    11581 gcagtgtgta tatatatata acaaataagc atttttaagt cttatcctta agtttctttt
    11641 attagtggca cttgtattat gctgtacttt ttattacata ttgtacaata tcttgtccat
    11701 ttgtttgcag cagagtaaaa ccggtttcta agttgta
//
