LOCUS       XM_005245918            5229 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens crystallin beta-gamma domain containing 2
            (CRYBG2), transcript variant X1, mRNA.
ACCESSION   XM_005245918
VERSION     XM_005245918.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_005245918.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5229
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..5229
                     /gene="CRYBG2"
                     /gene_synonym="AIM1L"
                     /note="crystallin beta-gamma domain containing 2; Derived
                     by automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 3 mRNAs, 38 ESTs, 60 long SRA reads, 3 Proteins, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 29 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:55057"
                     /db_xref="HGNC:HGNC:17295"
                     /db_xref="MIM:619765"
     CDS             141..5126
                     /gene="CRYBG2"
                     /gene_synonym="AIM1L"
                     /codon_start=1
                     /product="beta/gamma crystallin domain-containing protein
                     2 isoform X1"
                     /protein_id="XP_005245975.1"
                     /db_xref="GeneID:55057"
                     /db_xref="HGNC:HGNC:17295"
                     /db_xref="MIM:619765"
                     /translation="MEEAGGPMARAKARVVSATLTWRQRPPTQEEIKHGFHKVSLVSG
                     AQMEAPQKEMFEFSRREEVEVNGFATQEEETVNCQGPRDTAGSKNFQSHGPIFSKKYI
                     PPPKEKRPEGRLKEAVDQSDGSRQAPRTEPPCVGAMARTELLVPLPGPREPSPHPGVG
                     LTSGSSRSLEEYRVTRTVRTTTVVGGHVDRRMSSSVTVRPVSSGEALPRGRQVSRMVP
                     PVVVGSPPGSPSRSQAVKVLSNLVPAGHSPPASHLPRPTAGGPRSTGLGSTVGAALRQ
                     LPETGTAELKDSSALASTGIPASAHLPKNQDAPAACPDRDQGRAPDARACELWQVLGA
                     PSSTELPLQTSQGQASVPSSPRLETHVPSPGLTHPAKQPVVPTHPGARLTPLVLPPKK
                     KDGPVDPPAATVLPMVRSEHVTVPGQPPAPSTTRRKDVPSPGGLSAPSSPRNKFVQNS
                     ENVPVLPFTQREVVKGPGAPAASSPTRKEVVQGSSASAASSPTWKEVVKGPGAPAASS
                     PTQKEVVQGSSAPAALFPTWKEVVKGPGAPDASFPTWKEVVKGPGAPAASSPTQKEVV
                     QGSGAPAALSTTPKEVVKGPGAPAASSPTQKEVVKGPCAPAASSPTQKEVVQGSGAPA
                     ALSPKSTEVVQGPKGSSSIQKEAVQGIAGSLAPPLTKEETVQGPIAPATSLPKQDKGV
                     QDSEGSPISSLTQKEVVQDPDALPAPSSSVDRVSPSPGGTPAPVPTGAEASTESQLVS
                     DPTEGKTCTETSREEDEVALAADLEIFLDTLRSMEPPEILRTHRLPRAPRSSYLSMYA
                     TLPAIEEDQLGPWVLGPGPQEVPSLEEKEEEEEEEPENPYLSDDEKLQRRQEKAGPSP
                     SRDLHPARPTQVSCSPLEMMKKHVAGTKGPHSELGLELQGGSRPTSRLGGSLLFGSLV
                     PTAKEASTPEPLGTKLSALLPHGAPGLRKVPGQLPLLCSERSSPTEKLACSLPLEGWS
                     PALKTQGKLNTRPGKVIFFSESGCQGSGREVWGDIVDASGWAPVASIRVVRGCWVLYE
                     EPEFRGQKLVLPEGDMELRTPGTKWSPQGIGSLRRVVWDYSTPEISLFSEEGLKGEQV
                     KLTEALKNSQGLEKPLQVASATVSAGLWLLYPKPLFEDTPYILEPGEYPTSEAWGTSD
                     PSVGSLKPMRLGCPSVEKPGEPRAVVYEAPGFQGRSWEVSRDIYNLQQPEDSQSPHLA
                     SVGSLRVLGGCWVGYEKEGFRGHQYLLEEGEYPDWSHWGGYDELLTSLRVIRTDFGDP
                     AVVLFEAMDFEGHGVEVSKALPDVELVQHGPSTQAIHVLSGVWVAYQEVGFSGEQYVL
                     EKGVYRNCEDWGAGNSTLASLQPVLQVGEHDLHFVSKIQLFSRPDFLGDHFSFEDDQA
                     ALPASFRPQSCRVHGGSWILFDETNFEGDQHILSEGEFPTLTAMGCLASTVLGSLQKV
                     SLHFSEPSIFLYGLECFEGKEIELSREVRSLQAEGFNNHVLSVRIKGGIWVLCEHSDF
                     RGRQWLVGSCEITNWLTYSGTQRVGSLYPIKQRRVYFRLWNAALGGFLAVPDHVEDMK
                     AGRVVVADPQAGGSCIWYYEDGLLKNQMAPTMSLQVIGPPSPGSKVVLWAESRLPRQT
                     WSISESGHICSQMFEGQILDVKGGRGYDRDHVVLWEPDEDRASQIWTIHVL"
ORIGIN      
        1 agctgagagc ccaatcgcat caggggagca cggcccagca gcaggagctc caggctggct
       61 ggacacctgg gtccccacgc agactggagc tggaccacag tgggacaagg acacctccag
      121 acaggttgcc agggccccac atggaggagg caggtgggcc catggcccgg gccaaggccc
      181 gagtggtaag tgccacattg acatggcggc agcggccccc cacccaggaa gagatcaaac
      241 atggttttca caaggtgtcc ctggtgtcag gggcccagat ggaagccccg cagaaggaga
      301 tgtttgagtt cagccgtcga gaggaagtgg aagtcaatgg ctttgcaaca caggaagaag
      361 agactgtgaa ttgccagggc cctcgggata cagctggctc caagaacttc cagagccatg
      421 gacccatctt ttccaagaag tacataccac ctcccaagga gaaaaggcct gaggggaggc
      481 tgaaggaggc tgtggaccag agtgatggca gccgccaagc tcccaggact gagcccccat
      541 gtgtgggagc tatggccagg actgagcttt tggttcccct gcctgggccc cgagagccaa
      601 gtccccaccc aggtgtaggt ctcaccagtg gtagctcccg gagcctcgag gaataccgag
      661 tgacacgcac tgtgcggacc accacagtgg tgggaggtca tgtggaccgg cggatgagca
      721 gctctgtgac tgtgaggcca gtgtcctcag gcgaggccct gccacggggc cgtcaggtct
      781 cccgcatggt gccgccagtg gtggtgggct ccccaccagg ctcgcccagc cgcagccagg
      841 ccgtgaaagt gctaagtaac ctcgtgcctg ctgggcacag cccccctgcc agtcacctgc
      901 ccaggcccac ggctggcggg ccaaggagca caggtctggg cagcacagtg ggggcagcct
      961 tgaggcagct gcctgagacc gggacagcag agcttaaaga cagctctgcc ctggcctcta
     1021 caggcatccc agccagtgct cacctgccta agaatcagga tgcccctgca gcctgtccgg
     1081 acagagacca gggcagagcc ccggatgcca gggcctgtga gctctggcag gtgctgggag
     1141 cccccagttc cactgagctc cctctccaga cttctcaggg tcaagcatca gtcccctcct
     1201 ctcccagact cgagacccat gtcccctctc ctggcctaac tcaccctgca aagcagcctg
     1261 tggtgcccac tcaccccggg gcccggctca ctccccttgt tctgccccct aaaaaaaagg
     1321 acgggcccgt ggacccccct gctgccaccg tcctgcccat ggtgaggagc gagcatgtga
     1381 cagtccctgg acaacctcct gctccatcca ctacaagaag gaaggatgtc cccagcccag
     1441 gaggtctttc tgctccatcg tccccaagga ataagtttgt tcagaactct gaaaatgtcc
     1501 ctgtcctccc ctttacccag agggaggtcg tgaagggccc cggtgctcct gctgcctcat
     1561 ctcccacccg gaaggaggtg gtgcaggggt ccagtgcttc tgctgcctcg tcccccacct
     1621 ggaaagaggt cgtgaagggc cctggtgctc ctgctgcctc atctcccacc cagaaggagg
     1681 tggtgcaggg gtccagtgct cctgctgcct tgttccccac ctggaaagag gtcgtgaagg
     1741 gccccggtgc tcctgatgcc tcatttccca cctggaaaga ggttgtgaag ggccctggtg
     1801 ctcctgctgc ctcatccccc acccagaagg aggtggtgca ggggtctggt gctcctgctg
     1861 ccttgtccac caccccaaaa gaggttgtga agggccctgg tgctcctgct gcctcatcgc
     1921 ccacccagaa agaggttgtg aagggcccct gtgctcctgc tgcctcatct cccacccaga
     1981 aggaggtggt gcaggggtct ggtgctcctg ctgccttgtc ccccaagtca actgaggttg
     2041 tccagggccc aaaaggcagc agtagcatcc aaaaagaggc tgtccagggt attgcaggca
     2101 gccttgcccc gcccctcacc aaggaagaga ctgttcaagg cccaattgct cctgccacct
     2161 cactccccaa acaggataag ggggtccagg actctgaagg gagccccatc tcatctctca
     2221 cccagaaaga ggttgtgcag gaccctgatg ctctccctgc cccatcttcc tcagtggaca
     2281 gggtgtcccc cagcccagga ggcacccctg ccccagtgcc aacaggagca gaggccagca
     2341 cggagtccca gcttgtctct gatcccaccg agggcaagac gtgcacagag acatcaaggg
     2401 aggaggatga ggtggccctg gccgctgacc tggagatatt cctggatacg ctgcggagca
     2461 tggagccccc tgagatcctc cgcactcacc ggctgccacg agcccctcgc tcctcctacc
     2521 tgtccatgta cgccacgctg cctgccattg aggaggacca gctggggcca tgggtgctgg
     2581 gccccggacc ccaggaggtg ccttcactgg aagagaaaga ggaggaggag gaggaggaac
     2641 cagagaaccc ctatctgagt gacgatgaga agctccagcg caggcaggag aaagctgggc
     2701 ccagcccctc cagggacctc caccctgcca gacccaccca ggtctcctgc tctcctctgg
     2761 agatgatgaa gaagcatgta gcaggaacca agggccccca ctcagagctg ggattggaac
     2821 tgcagggagg cagcaggccc acttcccgtc ttggaggcag ccttctgttc ggcagtctgg
     2881 tgcctaccgc caaggaggcc tccaccccgg aaccgctggg cacaaaacta tctgctctgc
     2941 tgccccatgg ggcaccgggg ctcaggaagg tgccaggaca gttgcccctg ctttgcagtg
     3001 aaagatcatc cccaacggag aagcttgcct gttccctgcc cctggagggg tggagcccag
     3061 ccttaaagac ccagggcaag ctgaacacca ggcctggaaa ggtgatcttc ttctcagagt
     3121 ctggctgcca aggcagtggc agggaggtct ggggagacat cgttgatgcc tcaggctggg
     3181 cccccgtagc ctccataagg gtagttcgag gctgctgggt gctgtacgaa gagccagagt
     3241 tccggggtca gaagctggtc ctgcctgaag gagacatgga actcagaacc ccagggacaa
     3301 agtggagtcc ccaaggcatc ggctccctaa ggagggttgt ctgggactac agcaccccgg
     3361 aaatcagcct cttctctgag gagggcctca agggggagca agtgaagcta acagaggcct
     3421 tgaagaattc ccagggtctg gagaagcccc tgcaggtggc atctgccacc gtctctgcag
     3481 gactgtggct actgtacccc aaaccattat tcgaagacac tccctacatc ctggaacctg
     3541 gagagtaccc cacctcagag gcctggggca catcggaccc cagcgtgggc tccctgaagc
     3601 ccatgagatt gggctgccca agtgtggaga agccagggga gcccagggct gtggtgtatg
     3661 aggccccagg ctttcagggc cgcagctggg aagtgagccg agacatctac aaccttcagc
     3721 agccagagga cagccagagc ccccacctgg cctctgtggg gtccctgaga gttctcggag
     3781 gctgctgggt gggctacgag aaggagggct tccggggcca ccagtatctg ctggaggagg
     3841 gggaataccc agactggtca cactggggag gctatgacga gttgctgacc tccctccggg
     3901 tcatccggac ggacttcggg gacccggccg tcgtgctatt tgaggccatg gacttcgagg
     3961 ggcacggcgt ggaggtgagc aaggcattgc cggatgtgga gctggtgcaa cacggcccca
     4021 gcacacaggc catccacgtg ctcagcggcg tgtgggtggc ctaccaggag gtgggcttct
     4081 ccggggaaca gtacgtgctg gagaagggcg tgtatcgtaa ctgcgaggac tggggcgctg
     4141 gcaacagcac cctcgcctcg ctgcagccgg tcctacaggt cggggagcac gatctgcact
     4201 tcgtctcaaa gattcagctt ttctcccgcc ccgactttct gggcgaccac ttctctttcg
     4261 aagatgacca ggccgctctg cccgcctcct tccgacctca gtcctgccgg gtccacggcg
     4321 gcagctggat cctgtttgat gagacgaact tcgagggtga ccagcacatt ctctctgagg
     4381 gcgagttccc cactctcacg gccatgggct gcctcgcctc cacagtcctg ggctctctcc
     4441 agaaggtatc cctgcacttt tcagagcctt ccattttcct gtatggactc gagtgcttcg
     4501 aggggaagga gatcgagctc agcagggagg tgcggagcct gcaagccgag ggcttcaaca
     4561 accatgtgct gtctgtgcgg atcaaggggg gcatttgggt gctatgtgaa cacagtgact
     4621 tccggggccg ccagtggctg gtgggaagct gcgagatcac caactggctg acctacagcg
     4681 gcacccagag ggtgggctcc ctctacccca tcaagcagcg ccgggtttat ttccgcctct
     4741 ggaatgcagc actgggggga ttcctggcag tgccggacca tgtggaggac atgaaagcag
     4801 gccgtgtggt ggtcgccgac ccccaagctg gaggtagctg catctggtac tacgaggatg
     4861 ggctgctgaa gaaccagatg gcccccacca tgagcctaca ggtgattgga ccccctagcc
     4921 caggctccaa ggtggtgctg tgggccgaga gccgcctgcc gcgccagacg tggagcatca
     4981 gtgaatcggg ccacatctgc agccagatgt tcgaaggcca gatcctggac gtgaagggag
     5041 gccggggcta cgaccgggac cacgtggtgc tatgggagcc ggatgaggac agggcatccc
     5101 agatctggac tatccacgtg ctttgaaact tttcccctca ccctccagcc ctggaggctt
     5161 ttgctgggat gaatgttttt atagggtttt tgttgtaaca taagctattt tctaatatgc
     5221 tgccaggta
//
