LOCUS       NM_001351305            5370 bp    mRNA    linear   PRI 14-FEB-2024
DEFINITION  Homo sapiens ciliary rootlet coiled-coil, rootletin family member 2
            (CROCC2), mRNA.
ACCESSION   NM_001351305
VERSION     NM_001351305.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5370)
  AUTHORS   Gascoigne,D.K., Cheetham,S.W., Cattenoz,P.B., Clark,M.B.,
            Amaral,P.P., Taft,R.J., Wilhelm,D., Dinger,M.E. and Mattick,J.S.
  TITLE     Pinstripe: a suite of programs for integrating transcriptomic and
            proteomic datasets identifies novel proteins and improves
            differentiation of protein-coding and non-coding genes
  JOURNAL   Bioinformatics 28 (23), 3042-3050 (2012)
   PUBMED   23044541
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC104809.5, DV080499.1, DY655578.1, DY655577.1, DY655377.1,
            DV080412.1, DV080240.1, DV080150.1, DV080638.1, EG327310.1,
            EG327700.1, DT932542.1, BU682871.1 and BX091140.1.
            
            On Jun 2, 2019 this sequence version replaced NM_001351305.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMEA2144333, SAMEA2153307
                              [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000690015.1/ ENSP00000508848.1
            RefSeq Select criteria    :: based on manual assertion,
                                         conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-256               AC104809.5         98839-99094         c
            257-407             AC104809.5         86554-86704         c
            408-559             AC104809.5         85296-85447         c
            560-666             AC104809.5         82785-82891         c
            667-823             AC104809.5         79550-79706         c
            824-927             AC104809.5         75161-75264         c
            928-1125            AC104809.5         74302-74499         c
            1126-1222           AC104809.5         73016-73112         c
            1223-1429           AC104809.5         72522-72728         c
            1430-1520           AC104809.5         72209-72299         c
            1521-1659           DV080499.1         250-388
            1660-1887           DY655578.1         1-228               c
            1888-1929           DY655577.1         532-573
            1930-1940           AC104809.5         70984-70994         c
            1941-2139           DY655377.1         1-199
            2140-2397           DV080412.1         30-287              c
            2398-2496           AC104809.5         59222-59320         c
            2497-2625           DV080240.1         319-447             c
            2626-2655           AC104809.5         56338-56367         c
            2656-2939           DV080150.1         1-284               c
            2940-3007           AC104809.5         54920-54987         c
            3008-3121           AC104809.5         49458-49571         c
            3122-3237           AC104809.5         46014-46129         c
            3238-3474           DV080638.1         171-407             c
            3475-3601           EG327310.1         306-432             c
            3602-3602           AC104809.5         40846-40846         c
            3603-3943           EG327700.1         96-436
            3944-4139           AC104809.5         39437-39632         c
            4140-4324           AC104809.5         39021-39205         c
            4325-4368           AC104809.5         38042-38085         c
            4369-4500           DT932542.1         1-132
            4501-4579           AC104809.5         37168-37246         c
            4580-4729           AC104809.5         22401-22550         c
            4730-5018           BU682871.1         370-658             c
            5019-5019           AC104809.5         15619-15619         c
            5020-5237           BU682871.1         151-368             c
            5238-5370           BX091140.1         14-146              c
FEATURES             Location/Qualifiers
     source          1..5370
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q37.3"
     gene            1..5370
                     /gene="CROCC2"
                     /note="ciliary rootlet coiled-coil, rootletin family
                     member 2"
                     /db_xref="GeneID:728763"
                     /db_xref="HGNC:HGNC:51677"
     exon            1..256
                     /gene="CROCC2"
                     /inference="alignment:Splign:2.1.0"
     CDS             179..5140
                     /gene="CROCC2"
                     /note="rootletin-like; putative ciliary rootlet
                     coiled-coil protein-like 3 protein; putative ciliary
                     rootlet coiled-coil protein 2"
                     /codon_start=1
                     /product="ciliary rootlet coiled-coil protein 2"
                     /protein_id="NP_001338234.1"
                     /db_xref="CCDS:CCDS92994.1"
                     /db_xref="GeneID:728763"
                     /db_xref="HGNC:HGNC:51677"
                     /translation="MSSASSEPGNGDASQQPLLGLDTVIQRLEDTILSPTASREDRAL
                     TVRGEGRQASPTPVPTRIREIVAGSLSEEPPQAGVQEPTATVARVQEENELLQEELTR
                     LGDLLAQASAERDELASRCRVVSEQLQARLETTEAQLRRSELEHSVDLEEALGRLEAA
                     EERSTGLCQVNALLREQLEHMKKANDALGRELAGMTGSVQRLQGELELRRWAQRQTRS
                     GGLGQPRDLLLLWRQAVVLGTDLAELRVATERGLADLQADTARTARRLHTACLNLDSN
                     LRLSASSTASTLGQQLRDKAGEMLQLQGRWDAEKVALQARLSEQTLLVEKLTEQNEQK
                     AKTIAALRTDLQNLVAQEDARCLELAGSSITELGEPRRPLRSPQRATSPHQGASPPHI
                     CSPATLDPALQAMRAAIERRWRREQELCLQLKSSQALVASLQEQLSESRRELWAAQKL
                     QQERAREQAREREALRGQLEAQRLEVQQCRASCKLLGREKAALEMVVEELKGKADAAD
                     AEKQGLEAEAAELQRSLLLQAERREELALRRERSCRALETSQGRLQQLEEKVSGLREE
                     LASVREALSTAQLQRDVVESEREGLRSALARAECSNADLELLVRRLKSEGVEQRDSLA
                     AMAALMEGLAQDKSALNHLALQLEQERDQLREQRKTLEQERARAGEQLAQAEQQLALE
                     RAERRGLQQACGRLEQRQEQLEGQAALLGREKAQLQEQVGQVTCQKQALEEQLAQSLQ
                     DQEAQMGTLQQALQGKDALSEERAQLLAKQEALERQGRLAAEEAADLRVERDSLESSL
                     LEAQQLATKLQEQLEEEARSAGLARQALQVEMEQLQSDWEVQEMKLRQDTVRLQRQVA
                     QQEREAQRALESQALAHREALAQLQREKETLSLTLAEEKEVARCQLEQEKELVTKSAA
                     EREALKGEIQSLKQERDESLLQLEHKMQQALSLKETERSLLSEELSRARRTLERVQQE
                     AQSQQEQAQATISATTEELKALQAQFEDAITAHQRETTALRESLQDLAAERGDVEREA
                     ERLRAQLTVAQEGLAALRQELQGVEESREGLHREAQEARRALSDEAREKDVLLLFNSE
                     LRATICRAEQEKASFKRSKEEKEQKLLILEEAQAALQQEASALRAHLWELEQAGGDAR
                     QELRELHRQVRTLKAENQRRSGEAHELQAQCSQEVLELRRQAAKAEAKHEGARKEVLG
                     LQRKLAEVEAAGEAHGQRLQEHLRESRGAEQTLRAELHSVTRKLQEASGVADALQARL
                     DQACHRIHSLEQELAQAEGARQDAEAQLGRLCSTLRRGLGLQRQSPWASPEQPGSPTK
                     GSDSSQALPGQQGTSPPARPHSPLRWPSPTPGGRSSELMDVATVQDILRDFVQKLREA
                     QRERDDSRIQMATLSSRLSEAECRCARAQSRVGQLQKALAEAEEGQRRVEGALSSARA
                     ARALQKEALRRLELEHLASVRAAGQEKRRLQEQLETLRQALEESRRHSQGLAKQGKLL
                     EEQLTNLEHRCQKAEVSLEPLRQMEQETLKREEDVARLGAEKEQLDQSLNSLHQEVDG
                     ALRQNQQLQAQMTEMEQAHTQRLQDLTAQHQRDLATEAERLHGARPQATQALESQEWT
                     HQQQVKVLEEQVASLKEQLDQEVQWRQQAHLGQAFQTGHAQRD"
     exon            257..407
                     /gene="CROCC2"
                     /inference="alignment:Splign:2.1.0"
     exon            408..559
                     /gene="CROCC2"
                     /inference="alignment:Splign:2.1.0"
     exon            560..666
                     /gene="CROCC2"
                     /inference="alignment:Splign:2.1.0"
     exon            667..823
                     /gene="CROCC2"
                     /inference="alignment:Splign:2.1.0"
     exon            824..927
                     /gene="CROCC2"
                     /inference="alignment:Splign:2.1.0"
     exon            928..1125
                     /gene="CROCC2"
                     /inference="alignment:Splign:2.1.0"
     exon            1126..1222
                     /gene="CROCC2"
                     /inference="alignment:Splign:2.1.0"
     exon            1223..1429
                     /gene="CROCC2"
                     /inference="alignment:Splign:2.1.0"
     exon            1430..1641
                     /gene="CROCC2"
                     /inference="alignment:Splign:2.1.0"
     exon            1642..1824
                     /gene="CROCC2"
                     /inference="alignment:Splign:2.1.0"
     exon            1825..1969
                     /gene="CROCC2"
                     /inference="alignment:Splign:2.1.0"
     exon            1970..2116
                     /gene="CROCC2"
                     /inference="alignment:Splign:2.1.0"
     exon            2117..2347
                     /gene="CROCC2"
                     /inference="alignment:Splign:2.1.0"
     exon            2348..2541
                     /gene="CROCC2"
                     /inference="alignment:Splign:2.1.0"
     exon            2542..2660
                     /gene="CROCC2"
                     /inference="alignment:Splign:2.1.0"
     exon            2661..2830
                     /gene="CROCC2"
                     /inference="alignment:Splign:2.1.0"
     exon            2831..3007
                     /gene="CROCC2"
                     /inference="alignment:Splign:2.1.0"
     exon            3008..3121
                     /gene="CROCC2"
                     /inference="alignment:Splign:2.1.0"
     exon            3122..3265
                     /gene="CROCC2"
                     /inference="alignment:Splign:2.1.0"
     exon            3266..3483
                     /gene="CROCC2"
                     /inference="alignment:Splign:2.1.0"
     exon            3484..3643
                     /gene="CROCC2"
                     /inference="alignment:Splign:2.1.0"
     exon            3644..3781
                     /gene="CROCC2"
                     /inference="alignment:Splign:2.1.0"
     exon            3782..4139
                     /gene="CROCC2"
                     /inference="alignment:Splign:2.1.0"
     exon            4140..4324
                     /gene="CROCC2"
                     /inference="alignment:Splign:2.1.0"
     exon            4325..4445
                     /gene="CROCC2"
                     /inference="alignment:Splign:2.1.0"
     exon            4446..4579
                     /gene="CROCC2"
                     /inference="alignment:Splign:2.1.0"
     exon            4580..4729
                     /gene="CROCC2"
                     /inference="alignment:Splign:2.1.0"
     exon            4730..4861
                     /gene="CROCC2"
                     /inference="alignment:Splign:2.1.0"
     exon            4862..5041
                     /gene="CROCC2"
                     /inference="alignment:Splign:2.1.0"
     exon            5042..5124
                     /gene="CROCC2"
                     /inference="alignment:Splign:2.1.0"
     exon            5125..5370
                     /gene="CROCC2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5349..5354
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CROCC2"
                     /note="hexamer: AATAAA"
     polyA_site      5370
                     /gene="CROCC2"
                     /note="major polyA site"
ORIGIN      
        1 atactgtctt acccacaggg caagagcaac tgggtgccca ggctcgggac acaagactgc
       61 agagccaggt gccacacagg tgtggggccc gtggaccaag gaagaccctg gccagttgga
      121 ggagaactgc caggtagcaa agcccagact tctctggggt cctgcgctct gggctgcaat
      181 gagctctgcc tccagtgagc ctggcaatgg ggacgcctcc caacagcccc tactggggct
      241 ggacaccgtg atccagagac tggaggacac catcctgagt cccacagcca gcagggaaga
      301 ccgggcgctg accgtgcgtg gggaaggccg gcaggcctcg cccacccccg tgcccacccg
      361 catccgtgag atcgtggccg gcagcctgag tgaggagcca ccccaagcag gggtacagga
      421 gccgacagcc actgtggccc gagtgcaaga ggagaacgag ctcctgcagg aggagctgac
      481 ccggctgggg gacctgctgg cccaggccag cgccgagcga gatgagctgg ccagcaggtg
      541 ccgtgtggtc agcgagcagc tgcaggcccg gctggagacc accgaggctc agctgcggag
      601 gtcagagctg gagcacagcg tggatctgga ggaggccctt ggccgtctgg aggctgccga
      661 ggagaggagc accggcctct gtcaggtgaa cgcgctcctg cgggagcagc tggaacatat
      721 gaagaaggcc aatgacgcgc tgggccggga gctggccggg atgacgggca gcgtgcagcg
      781 cctgcagggc gagctggagc tgaggcgctg ggcccagaga cagacccggt cagggggcct
      841 ggggcagccc cgggacctcc tcctcctgtg gagacaggcc gtggtgctgg ggacagacct
      901 ggccgagctg cgtgtagcca ctgagagggg cctcgctgac ctgcaggcag acacggccag
      961 gacagcccgc cgcctgcaca ccgcctgcct gaacctcgac tccaacctgc ggctgtcggc
     1021 cagcagcacg gccagcaccc tggggcagca gcttcgggac aaggctgggg agatgctgca
     1081 gctgcagggc cgctgggacg cagagaaggt ggcgctccag gccagactct cggagcaaac
     1141 cctgctggtg gagaagctta cagagcagaa tgagcagaag gcgaagacca tcgctgccct
     1201 cagaaccgac ctgcagaacc tggtggccca ggaggacgcc cggtgcctgg agctggcagg
     1261 tagcagcatc actgaattgg gggagccacg gcgcccactg aggagccccc aacgtgccac
     1321 atccccccat caaggggcgt ccccaccaca catctgctcc ccagccaccc tggaccccgc
     1381 actgcaggcc atgcgggcag ccatagagag gcggtggcgg cgggaacagg agctgtgcct
     1441 gcagctgaag tcctcccagg cactggtggc cagtctccag gagcagctgt ccgaaagccg
     1501 gcgggagctg tgggccgcac agaagctcca gcaggagcgg gctcgggagc aggcacggga
     1561 acgagaggct cttcggggcc agctggaggc ccagaggctc gaggtgcagc agtgccgggc
     1621 atcctgcaag ctcctgggga gggagaaggc tgctctggag atggtggtgg aggagctgaa
     1681 agggaaggca gatgctgcag atgcggagaa gcaggggctg gaggccgagg ctgcagagct
     1741 gcagagaagc ctcctgctgc aggcagagcg gagggaggag ctggctctgc ggagggagcg
     1801 gagctgcagg gcactggaga ccagtcaagg ccgcctgcag cagctggagg agaaggtctc
     1861 cgggctcaga gaggagctgg catcggtccg ggaggcactg agcacagcac agctgcagcg
     1921 ggatgtcgtg gagagtgaga gggagggact gcgcagcgcc ctggcgcggg ccgagtgcag
     1981 caatgcggac ctggagcttc ttgtgaggcg gctgaagtcg gagggagtgg agcaaaggga
     2041 ctccctggcc gcaatggccg ccttgatgga ggggttggct caggacaaaa gtgccctgaa
     2101 ccacctggct ctccagctgg agcaggagcg ggaccagctg cgggaacagc ggaagactct
     2161 ggagcaggaa cgggcccggg ccggggagca gctggcacag gcggagcagc agctggcgct
     2221 ggagcgggca gagcgcaggg gcctgcagca ggcctgcgga cgcctggagc agcggcagga
     2281 gcagctggag gggcaggcag ccctgctggg gcgagagaag gcccagctcc aggagcaggt
     2341 gggccaggtc acatgccaga aacaggccct ggaggagcag ctggctcaga gcctgcagga
     2401 ccaggaggcc cagatgggca ctctgcagca agccctgcaa ggaaaggatg ctctgtctga
     2461 ggagcgggcc cagctgctgg ccaagcagga ggccttggag aggcagggcc ggctcgcagc
     2521 tgaagaggca gctgatctca gggtggagag ggactccctg gagagcagcc tccttgaggc
     2581 ccaacagctg gccacaaagc tgcaggagca gctggaggag gaagcccgga gcgcaggact
     2641 cgcgcggcag gccttgcaag tggaaatgga gcagctacaa agtgactggg aggtccagga
     2701 aatgaagctg cggcaggaca cggtgcggct ccagcgacag gtggcacagc aggagcggga
     2761 ggcacagcgg gccctggaga gccaggcgtt ggcccaccga gaggccctgg cacagctcca
     2821 aagggagaag gagaccctga gcctgaccct ggcagaggag aaggaggtag ccagatgcca
     2881 gctggagcag gagaaggagc tggtgacaaa aagtgcagct gagagggagg ctctgaaggg
     2941 ggaaattcag agcctgaagc aggagcggga cgagagcctt ctccaactgg agcacaagat
     3001 gcaacaggcc ctgtccctga aagaaacaga gcggagcctt ctgagtgagg agctctccag
     3061 ggccaggagg acgctagagc gggtacagca ggaggcacag agccagcagg agcaagcgca
     3121 ggccaccatc agtgccacga ctgaggagct gaaggccctc caggcccagt ttgaggatgc
     3181 catcacagcc catcagaggg agaccacggc cctacgcgag agcctccagg acctagcggc
     3241 tgagcggggc gatgtggaga gagaggctga gaggctgcgg gcacagctga ccgtggccca
     3301 ggagggactg gccgcactgc gccaggagct gcagggcgtc gaggagagcc gggaggggct
     3361 gcacagggag gcccaggagg cccgccgggc gctgagtgac gaggcccgcg agaaggacgt
     3421 actgttgctt ttcaacagcg agctgcgggc caccatctgc agggccgaac aggagaaggc
     3481 cagttttaag cggtccaagg aggagaagga gcagaagctg ctcatcctgg aggaggccca
     3541 ggcggcgttg cagcaggagg ccagtgcact gcgggcccac ctgtgggagc tggagcaggc
     3601 agggggggac gcccgtcagg agctccggga actccacaga caggtgagga cactgaaggc
     3661 cgagaaccag aggaggagtg gagaggccca tgagctgcag gcgcagtgct cgcaggaggt
     3721 gctggagctg cggaggcagg cagccaaggc agaggccaag cacgagggtg cccggaagga
     3781 ggtcctggga ttgcagagga agttggcaga ggtggaggcc gcaggggagg cccatggaca
     3841 gcggctccag gagcacctcc gtgagagccg gggggctgag cagaccctcc gagcagagct
     3901 gcacagtgtc accaggaagc tgcaggaagc cagtggtgtg gctgatgctc tccaggctcg
     3961 cctggaccag gcctgtcacc gaatccacag cctggagcag gagctggccc aggctgaggg
     4021 tgcaaggcag gatgcggagg cccagctggg ccggctgtgc tccacgctcc gccgtggcct
     4081 ggggctccag agacagagcc cgtgggcctc cccggagcag cctggttccc ccaccaaagg
     4141 ctccgacagc tcccaggctc tccctgggca acagggtacc agccccccag ccaggcccca
     4201 ctcgcccctc cgatggccct cgcccacacc cggaggccgc agctcagagc tcatggatgt
     4261 ggccaccgtg caggacatcc tgcgggactt tgtgcagaag ctccgggaag cccagcggga
     4321 gcgggatgac tcccgcatcc agatggcgac cctgagcagc cggctgagcg aggcagagtg
     4381 caggtgtgcc cgggcccaga gccgcgtggg gcagctgcag aaagccctgg ctgaggcgga
     4441 agaaggccag cgccgggtgg agggcgcgct gagcagcgcc cgggcagcac gtgccctgca
     4501 gaaggaggcg ctccgcaggc tggagttgga gcacctggcg agcgtgcgtg cggcaggcca
     4561 ggagaagcgg cggctgcagg agcaactgga aacgctgcgc caggctcttg aagagagcag
     4621 gaggcacagc caaggtctgg ccaagcaggg gaagctgctg gaagaacagc tcaccaactt
     4681 ggagcacagg tgccagaagg ctgaggtatc gctggagccc ctgcgacaga tggagcaaga
     4741 gacactgaag agggaggagg atgtggcgag gctgggggct gagaaggagc agctggacca
     4801 gtctctgaac agcctgcacc aggaggtgga cggagccctg aggcaaaatc agcagctgca
     4861 ggcccagatg acagagatgg agcaggccca cacccagcgg ctccaggacc tgacagctca
     4921 gcaccagcgg gacctggcca cagaggcaga gcgtctccat ggggcccggc cgcaggccac
     4981 gcaggccctg gagtcccaag aatggaccca ccagcagcag gtaaaggtgc tggaagagca
     5041 ggtggccagc ctgaaggagc aactggacca ggaagtgcag tggcggcaac aggcccacct
     5101 cggccaggcc ttccagacag gacacgccca aagggactga agctcccagc acaggggagg
     5161 cgcccagcgt ggctgcagag gaagggaacg caccgcaggt gggaggggcc cagctgattt
     5221 ctcagcgtca cagtgaaagg cacccgtgat gagacagctc gctctcggca gtttcaggac
     5281 cctccttgcc ctggctgctc atggggaaca tttgaaatgc atgtgggggc ctccgaattt
     5341 tgaattttaa taaatagttg aatcagcgta
//
