LOCUS       XM_006714822            7953 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens CREB3 regulatory factor (CREBRF),
            transcript variant X1, mRNA.
ACCESSION   XM_006714822
VERSION     XM_006714822.5
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000005.10) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_006714822.4.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7953
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="5"
     gene            1..7953
                     /gene="CREBRF"
                     /gene_synonym="C5orf41; LRF"
                     /note="CREB3 regulatory factor; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 3
                     mRNAs, 10 ESTs, 627 long SRA reads, 7 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 87 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:153222"
                     /db_xref="HGNC:HGNC:24050"
                     /db_xref="MIM:617109"
     CDS             495..2414
                     /gene="CREBRF"
                     /gene_synonym="C5orf41; LRF"
                     /codon_start=1
                     /product="CREB3 regulatory factor isoform X1"
                     /protein_id="XP_006714885.1"
                     /db_xref="GeneID:153222"
                     /db_xref="HGNC:HGNC:24050"
                     /db_xref="MIM:617109"
                     /translation="MPQPSVSGMDPPFGDAFRSHTFSEQTLMSTDLLANSSDPDFMYE
                     LDREMNYQQNPRDNFLSLEDCKDIENLESFTDVLDNEGALTSNWEQWDTYCEDLTKYT
                     KLTSCDIWGTKEVDYLGLDDFSSPYQDEEVISKTPTLAQLNSEDSQSVSDSLYYPDSL
                     FSVKQNPLPSSFPGKKITSRAAAPVCSSKTLQAEVPLSDCVQKASKPTSSTQIMVKTN
                     MYHNEKVNFHVECKDYVKKAKVKINPVQQSRPLLSQIHTDAAKENTCYCGAVAKRQEK
                     KGMEPLQGHATPALPFKETQELLLSPLPQEGPGSLAAGESSSLSASTSVSDSSQKKEE
                     HNYSLFVSDNLGEQPTKCSPEEDEEDEEDVDDEDHDEGFGSEHELSENEEEEEEEEDY
                     EDDKDDDISDTFSEPGYENDSVEDLKEVTSISSRKRGKRRYFWEYSEQLTPSQQERML
                     RPSEWNRDTLPSNMYQKNGLHHGKYAVKKSRRTDVEDLTPNPKKLLQIGNELRKLNKV
                     ISDLTPVSELPLTARPRSRKEKNKLASRACRLKKKAQYEANKVKLWGLNTEYDNLLFV
                     INSIKQEIVNRVQNPRDERGPNMGQKLEILIKDTLGLPVAGQTSEFVNQVLEKTAEGN
                     PTGGLVGLRIPTSKV"
ORIGIN      
        1 gtttcgggtg tccgaaggcg agtccgatcg gaccaggaag tagctcaggg gagcctgacc
       61 tcgacccgcc tttctcctca cacgagctga ggaggcaggg aagtaccgag ggcagtcaag
      121 cctcccctgg gggtggttcc tgggactaga tggagctcag tctctggatt ctccctcttt
      181 ctcggcccta tgcttcctga cagacctggc cgccaaaccc tgtaatcgcc ctcctttaac
      241 ccaagaaagc aagtctttct gccgtttctg agctggcttg agccttaaga ctaccttaag
      301 gagacagcat cgcacagaat tattttaaaa aaaagcagtg atccaagcaa ttgaattgga
      361 agcactctgg ggaaacctgc tgtttattgt ggaaatcatc ttcgatcttg gaattgaaag
      421 taaagctgga aaggaattta caaacaagaa aaaaaagaag tttggaatcg gattcacagg
      481 atctgggctt ggaaatgcct cagcctagtg taagcggaat ggatccgcct ttcggggatg
      541 cctttcgaag ccacaccttt tcggaacaaa ctctgatgag cacagatctc ttagcaaaca
      601 gttcggatcc agatttcatg tatgaactgg atagagagat gaactaccaa cagaatccta
      661 gagacaactt tctttctttg gaggactgca aagacattga aaatctggag tctttcacag
      721 atgtcctgga taatgagggt gctttaacct caaactggga acagtgggat acatactgtg
      781 aagacctaac gaaatatacc aaactaacca gctgtgacat ctggggaaca aaagaagtgg
      841 attacttggg tcttgatgac ttttctagtc cttaccaaga tgaagaggtt ataagtaaaa
      901 ctccaacttt agctcaactt aatagtgagg actcacagtc tgtttctgat tccctttatt
      961 accccgattc acttttcagt gtcaaacaaa atcccttacc ctcttcattc cctggtaaaa
     1021 agatcacaag cagagcagct gctcctgtgt gttcttctaa gactctgcag gctgaggtcc
     1081 ctttgtcaga ctgtgtccaa aaagcaagta aacccacttc aagcacacaa atcatggtga
     1141 agaccaacat gtatcataat gaaaaggtga actttcatgt tgaatgtaaa gactatgtaa
     1201 aaaaggcaaa ggtaaagatc aacccagtgc aacagagccg gcccttgttg agccagattc
     1261 acacagatgc agcaaaggag aacacctgct actgtggtgc agtggcaaag agacaagaga
     1321 aaaaagggat ggagcctctt caaggtcatg ccactcccgc tttgcctttt aaagaaaccc
     1381 aggaactatt actaagtccc ctgccccagg aaggtcctgg gtcacttgca gcaggagaga
     1441 gcagcagtct ttctgccagt acatcagtct cagattcatc ccagaaaaaa gaagagcaca
     1501 attattctct ttttgtctcc gacaacttgg gtgaacagcc aactaaatgc agtcctgaag
     1561 aagatgagga ggacgaggag gatgttgatg atgaggacca tgatgaagga ttcggcagtg
     1621 agcatgaact gtctgaaaat gaggaggagg aagaagagga agaggattat gaagatgaca
     1681 aggatgatga tattagtgat actttctctg aaccaggcta tgaaaatgat tctgtagaag
     1741 acctgaagga ggtgacttca atatcttcac ggaagagagg taaaagaaga tacttctggg
     1801 agtatagtga acaacttaca ccatcacagc aagagaggat gctgagacca tctgagtgga
     1861 accgagatac tttgccaagt aatatgtatc agaaaaatgg cttacatcat ggaaaatatg
     1921 cagtaaagaa gtcacggaga actgatgtag aagacctgac tccaaatcct aaaaaactcc
     1981 tccagatagg caatgaactt cggaaactga ataaggtgat tagtgacctg actccagtca
     2041 gtgagcttcc cttaacagcc cgaccaaggt caaggaagga aaaaaataag ctggcttcca
     2101 gagcttgtcg gttaaagaag aaagcccagt atgaagctaa taaagtgaaa ttatggggcc
     2161 tcaacacaga atatgataat ttattgtttg taatcaactc catcaagcaa gagattgtaa
     2221 accgggtaca gaatccaaga gatgagagag gacccaacat ggggcagaag cttgaaatcc
     2281 tcattaaaga tactctcggt ctaccagttg ctgggcaaac ctcagaattt gttaaccaag
     2341 tgttagagaa gactgcagaa gggaatccca ctggaggcct tgtaggatta aggataccaa
     2401 catcaaaggt gtaatcagcc tcattggacc actggtcaga aatgtctgcg ttttgtcacg
     2461 ttatccattg taaattttca ttctgttttg catgtcagtt agcattatgt aaacatttac
     2521 aattaggtta cattgtttta agaactaagt agcataagtg aagcatgatc caaaatactt
     2581 gattattgca ttttcagagc ataaaccatg attaaaactg ctactggcat cagaattgaa
     2641 aatcatatgt ttaagtaaat gttaggtaca gattacaaaa atctgttaaa gcaaaacatt
     2701 ttggaggagt gaaatagtaa aatgccaagt attgtggcag atttatgctc tgaaccacac
     2761 aaaaaaattg aggaagcatt tttttaaaca gtcggtttaa attgttttta gaattattgc
     2821 tttttgttct aattttccac aaccattaat ctcacttgta tatggcacac ccagcacttg
     2881 tgcctgtggg ccatattaga tgttcattgt cagagctcaa gatgatatat ataaatatat
     2941 atatatatat atatatatac acacacacac acaaatgtct gtgcaagtaa gaaaaaaaaa
     3001 gcatattctt tgtgccttgt attttgggga aactctaaaa ctggtaatat tttgtatgat
     3061 gaaaacccta atgagaaaaa acaagatata tagatggaaa aattatgggg tttaaatgtt
     3121 tttttgttcc aactcttttt cagatttttt gaatgtatat aggactatgt tgaaatgtag
     3181 atatatgcca cagagtctgt gtattgtata aaaaacaaaa caaaaaacaa caaaaaaaag
     3241 atggctctag aaaactcata tttcggtact tgaccggaag aagacaaata cttgcacatt
     3301 attgcgattg ttttattttt tgtaccaaag acaaatgcaa ctgatatggc aaactgccag
     3361 tctaagtaaa gttttgcaca gcttacatga tactgtatga atgtatgaaa aaaaaggaga
     3421 aaaaaaagaa aaaaaaaggt cagggttagg gatcttactg aactgtgaat tttatttctg
     3481 tttgggtcca attatctaca gaaggagcat ccatacatac aaatattatt ttgctgttcc
     3541 tctagttcgc ttccatagta gataagttgg tggccattta gatgtctttt atttctgcac
     3601 ttattgtagg aaattttaat atatttcatt ttagtaagct attgataaaa tagtttttga
     3661 ctttgaaaat taaaatgttt atttagctta ttgtagtata cttccaccag acaacaaaat
     3721 agattatttt tattgtatta tgtatatata tatatgtaaa gaaagaaaaa agctaaaaat
     3781 atctaattct ttagttgcca cttttccgat tgatgtatta ttgtgcatgt aatattttca
     3841 aagatcaaca caggctaaaa caaaaacaat ttatagattt ttatattttt gtacaggtat
     3901 tttcaaacta gcttcttcaa acttaacatg tgacttattc ttctatagtt tctagaattg
     3961 agaaacatta acacatttag tttttaggtg ctcttttttg ctcatataaa acagcttcat
     4021 tagtcagtgt tttaactgtg ttcaagcttt acctcttgat gagaaatttc ttatgtcaag
     4081 gcagcattat aaaccttccc ccacagattt ttccatcctg tctctcttac tgttttattc
     4141 tcaaatcttg tgctttgaac tctgaaaact ggtggcttaa aaactaaaaa aagaaaaaaa
     4201 gcatatttag caaggaaaaa aataccaaaa atttcaggca tagctgctgg aaaaattatc
     4261 tatttctcca ttacccactg taggatttct tttttaatta tactttgact ataaagtgtc
     4321 aaagtataat ttgttctttt cttttacttt gttaccccat ttgtaagcta tagcatatga
     4381 agctatatat atagcttgtg aaggtttgat ctagaacacc cagtaacaaa tgaacaatgt
     4441 tgcttacctg cttctttgac atcttaaaaa agaaatccaa ggaggattgt aaggattgtc
     4501 ttaccacctt agctgaactg tgatgcacaa gatttttcta tgtgtttggt ggaaatgtac
     4561 ctggtttgta cattcacgct aaacagatga taagctcaag tctgatggtt taatagaatg
     4621 taagttcatc gtttaaagct tttccttttt aggttggaga aggcaaaaca caggcttgca
     4681 agttggaagt atatgaagtc ttgacagagt gtgtctggta aattgaaaag tgtttcaaac
     4741 tatggcagtt ttgcaatcag gtgaaaatca cctcatgata ttcagctgat aaggtttata
     4801 aaattgcccc tttctagctg ctctgttagg aattctggtt tttgatactt ttttcctgtc
     4861 tgcaaaccag aatttgattt tttggtcttg catttcaaaa aaaaaaagac tttgaatctg
     4921 tttagtagat tccatatctt tgagtttcag tgttttatat gtactactta agttaaatag
     4981 ttaaaagctt ttaaatagtt gagcttttta atgttgacac tttattttgt acctatttat
     5041 atatgtatgt atatcttaga aaagcacttt gttaaaaaaa aattgcattt tatatgattc
     5101 ctgccatttg ctgctaaatc tgggctggtc agaatgctgc agcgatactt gatctatata
     5161 aaaacctggc agtaaaatgt agagtgaaag ttaaatcctc ttgctgtttt aactttatca
     5221 taaagatgac ataggcaagc tgtgcagctt tacattttaa ccaggggact ctgtggcatt
     5281 taaaaccgtc tagaaatggt tgtactttaa tgccagtaat aatctgcttc ctctattgtc
     5341 attaaaatat atacgtttag tgtatcacac aaaccaatct tataagggta atgtaaaaac
     5401 cccaacaatt gtacatgttc tgtttttgaa aattgtggca tgtatttttg ggtgaagatc
     5461 attagagaag agttctctaa aggttttctg tgttcataca tggtatacag atagctcata
     5521 atgaagtcca gaatcttact tttaagtgaa ggcattgtga attcacctca agtaaaccca
     5581 ttgttccaaa gcaattataa actttgactc tagtactact atgatttaaa aaaaaaaaaa
     5641 accaacaaaa accttttttc ctagtttcag atacactgga ttctttatag agtttgtctc
     5701 catatgaaag catgctgtcc agtcgctctt gttaagatct tgtctgagtt ttgaattggg
     5761 tgccacactt ttccagtcaa tataattgct tgttctactg taccatgtat gattcttgtc
     5821 ctttcctata tccttcatga cagattatga tgtggcttta tattgtgcct tacttgtaca
     5881 tttaaaacta aacgtcttca ttcccttcca cttcctacat ctttaacttt gacctttttg
     5941 gtaagagaat cagaactatt acaaaagcat catgaaggat ttcagatggg tatggtttca
     6001 aattccctct ctttatagtt attttatatt tgtatgaaag accagttttg gatggtcttt
     6061 gaatataggg gggaaagatt agcagtaatt tcactacatc ccttttctct gactttcatg
     6121 catttctcat acatcttctt tctgatgctt gactttattt gcttcctagc aatagtctgc
     6181 atttaaagaa aggtgtgttc aattcatcag cttgaaattg actatttcat ttttccagga
     6241 ttttttagga gaagagtacc cattttgttt tataaaaaca gatgacaagt ctctttaaaa
     6301 gaaacagaag tacagtactt ttgaaataca atgctgttag tttggatttc tttttatata
     6361 tatatataat attcatacaa tgatctgatg tttgccttca ttaataaagc tgttagttta
     6421 ttcaccaaaa tgtcaagaat ggatgtgctt ttctttattc cacacattta aaaaaattta
     6481 gctgctaaga tttaatgtta taagaaatga attcaagttg ccttcagcaa gaattaacaa
     6541 aaacttatgt tccctttctt tatatagttt cctaaaattc tgttcaagta ttttctagtt
     6601 aattatgtaa cagaatgtta gcatctctcc atatcttgaa acttgaattt tgagaatgca
     6661 ttgaattatg ctttcagtgt taaagtaaaa ggtttcaatt atccttctag tgaagtctgt
     6721 tgtggaatac catttcccat ggaactgagg ccatttccac aactttgcac agaactgcag
     6781 tcttgttctt cccttggatc atgacaaata agtctcacac agtgccgtaa tacttgtgga
     6841 ttcttttgta atctttgtaa tcttaataag ggcattatga gaagacgact ccatgttttt
     6901 ttaatacttc aaacacattg ggatgtaaca atgaatgtca actgtaggaa tggtggtttc
     6961 gttttaagga ataagcatgt tggggaaaga tgatgaaaat gtactactga aagttataca
     7021 cttccatagg caaatgggat tatgtgttga agcatagtcc tcatgcttaa taaactgact
     7081 gaaatcgtag aaattacacc taggaactga gctaggccaa attgccattt ttgtttagag
     7141 agttttggag gtagtagtga ggggacagag ccttaaaact acttccaaac agtattttgg
     7201 aattgaagac ttggtaacta gtgaagaaca tcaaagttgg gtatttcaat gtgccaagtt
     7261 tgggtgaact aggttcggtt tgcctctttc ataacaatgt aaacacaatg gtgtagttaa
     7321 ttaaattctg ggtggatagg agcaggactg attactatgt cttgcccttc gccctttgtt
     7381 tttttcagaa ccaaataaca gaaatgtgta tgtgtgtact gtatctgcct ttccaccaca
     7441 tttttatgac actgtattcc actgcctgct tttttacctt ctttccctag gatttgtcct
     7501 acagcttagt attgtggttg acagcgatac tagggctgac agcacagaag tcacaagaga
     7561 agagtggaag ggcaagaatt caaagcattt gttcatacaa tgtggcaacc tcttttgcat
     7621 agttgcgtag gatcctgttt gtaatgctat cataaatatt ctgtagtttt ttttttttct
     7681 ctcccaactg gagctatgac actttttatt ggattcagtc ttgtctcttg tctagaaaga
     7741 actttatctt gttgacgcat gagctgttta aaaattatcc tattaaatgt tggttaatag
     7801 ttgtgcagtt tttcatttca gatggaaagg caatgcaaat tttgcctttg ttttctgtca
     7861 ccttccaacc cctgagcact tctagtcaga tacagattca tcagtgtatg caacatcctt
     7921 tgtaatttaa aataaaaaaa gatgaaaaga aaa
//
