LOCUS       XM_047416575            3946 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens crumbs cell polarity complex component 1
            (CRB1), transcript variant X6, mRNA.
ACCESSION   XM_047416575
VERSION     XM_047416575.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3946
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..3946
                     /gene="CRB1"
                     /gene_synonym="CRB1-A; CRB1-B; CRB1-C; LCA8; RP12"
                     /note="crumbs cell polarity complex component 1; Derived
                     by automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 1 mRNA, 18 ESTs, 74 long SRA reads, 2 Proteins, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 5 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:23418"
                     /db_xref="HGNC:HGNC:2343"
                     /db_xref="MIM:604210"
     CDS             11..3370
                     /gene="CRB1"
                     /gene_synonym="CRB1-A; CRB1-B; CRB1-C; LCA8; RP12"
                     /codon_start=1
                     /product="protein crumbs homolog 1 isoform X5"
                     /protein_id="XP_047272531.1"
                     /db_xref="GeneID:23418"
                     /db_xref="HGNC:HGNC:2343"
                     /db_xref="MIM:604210"
                     /translation="MLWGPISATVPLDSWGITVNSTLMSVPVNLVSMEGCVWMEKTGY
                     TGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGF
                     TGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTH
                     QQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIATTLSFEGDGFLWVKSGSVTTKG
                     SVCNIALRFQTVQPMALLLFRSNRDVFVKLELLSGYIHLSIQVNNQSKVLLFISHNTS
                     DGEWHFVEVIFAEAVTLTLIDDSCKEKCIAKAPTPLESDQSICAFQNSFLGGLPVGMT
                     SNGVALLNFYNMPSTPSFVGCLQDIKIDWNHITLENISSGSSLNVKAGCVRKDWCESQ
                     PCQSRGRCINLWLSYQCDCHRPYEGPNCLREYVAGRFGQDDSTGYVIFTLDESYGDTI
                     SLSMFVRTLQPSGLLLALENSTYQYIRVWLERGRLAMLTPNSPKLVVKFVLNDGNVHL
                     ISLKIKPYKIELYQSSQNLGFISASTWKIEKGDVIYIGGLPDKQETELNGGFFKGCIQ
                     DVRLNNQNLEFFPNPTNNASLNPVLVNVTQGCAGDNSCKSNPCHNGGVCHSRWDDFSC
                     SCPALTSGKACEEVQWCGFSPCPHGAQCQPVLQGFECIANAVFNGQSGQILFRSNGNI
                     TRELTNITFGFRTRDANVIILHAEKEPEFLNISIQDSRLFFQLQSGNSFYMLSLTSLQ
                     SVNDGTWHEVTLSMTDPLSQTSRWQMEVDNETPFVTSTIATGSLNFLKDNTDIYVGDR
                     AIDNIKGLQGCLSTIEIGGIYLSYFENVHGFINKPQEEQFLKISTNSVVTGCLQLNVC
                     NSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHCT
                     CEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVC
                     GNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLN
                     KFQCLCDVAFAGERCEVDLADDLISDIFTTIGSVTVALLLILLLAIVASVVTSNKRAT
                     QGTYSPSRQEKEGSRVEMWNLMPPPAMERLI"
ORIGIN      
        1 acttgtcagg atgctctggg ggcctatttc tgcgactgtg cccctggatt cctgggggat
       61 cactgtgaac tcaacactga tgagtgtgcc agtcaacctt gtctccatgg agggctgtgt
      121 gtggatggag aaaacaggat acacaggtgc ccagtgtgag atcgacctca atgaatgcaa
      181 tagtaacccc tgccagtcca atggggaatg tgtggagctg tcctcagaga aacaatatgg
      241 acgcatcact ggactgcctt cttctttcag ctaccatgaa gcctcaggtt atgtctgtat
      301 ctgtcagcct ggattcacag gaatccactg cgaagaagac gtcaatgaat gttcttcaaa
      361 cccttgccaa aatggtggta cttgtgagaa cttgcctggg aattatactt gccattgccc
      421 atttgataac ctttctagaa ctttttatgg aggaagggac tgttctgata ttctcctggg
      481 ctgtacccat cagcaatgtc taaataatgg aacatgcatc cctcacttcc aagatggcca
      541 gcatggattc agctgcctat gtccatctgg ctacaccggg tccctgtgtg aaatcgcaac
      601 cacactttca tttgagggcg atggcttcct gtgggtcaaa agtggctcag tgacaaccaa
      661 gggctcagtt tgtaacatag ccctcaggtt tcagactgtt cagccaatgg ctcttctact
      721 tttccgaagc aacagggatg tgtttgtgaa gctggagctg ctaagtggct acattcactt
      781 atcaattcag gtcaataatc agtcaaaggt gcttctgttc atttcccaca acaccagcga
      841 tggagagtgg catttcgtgg aggtaatatt tgcagaggct gtgaccctta ccttaatcga
      901 cgactcctgt aaggagaaat gcatcgcgaa agctcctact ccacttgaaa gtgatcaatc
      961 aatatgtgct tttcagaact cctttttggg tggtttacca gtgggaatga ccagcaatgg
     1021 tgttgctctg cttaacttct ataatatgcc atccacacct tcgtttgtag gctgtctcca
     1081 agacattaaa attgattgga atcacattac cctggagaac atctcgtctg gctcatcatt
     1141 aaatgtcaag gcaggctgtg tgagaaagga ttggtgtgaa agccaacctt gtcaaagcag
     1201 aggacgctgc atcaacttgt ggctgagtta ccagtgtgac tgccacaggc cctatgaagg
     1261 ccccaactgt ctgagagagt atgtggcagg cagatttggc caggatgact ccactggtta
     1321 tgtcatcttt actcttgatg agagctatgg agacaccatc agcctctcca tgtttgtccg
     1381 aacgcttcaa ccatcaggct tacttctagc tttggaaaac agcacttatc aatatatccg
     1441 tgtctggcta gagcgcggca gactagcaat gctgactcca aactctccca aattagtagt
     1501 aaaatttgtt cttaatgatg gaaatgtcca cttgatatct ttgaaaatca agccatataa
     1561 aattgaactg tatcagtctt cacaaaacct aggatttatt tctgcttcta cgtggaaaat
     1621 cgaaaaggga gatgtcatct acattggtgg cctacctgac aagcaagaga ctgaacttaa
     1681 tggtggattc ttcaaaggct gtatccaaga tgtaagacta aacaaccaaa atctggaatt
     1741 ctttccaaat ccaacaaaca atgcatctct caatccagtt cttgtcaatg taacccaagg
     1801 ctgtgctgga gacaacagct gcaagtccaa cccctgtcac aatggaggtg tttgccattc
     1861 ccggtgggat gacttctcct gttcctgtcc tgccctcaca agtgggaaag cctgtgagga
     1921 ggttcagtgg tgtggattca gcccgtgtcc tcacggagcc cagtgccagc cggtgcttca
     1981 aggatttgaa tgtattgcaa atgctgtttt taatggacaa agcggtcaaa tattattcag
     2041 aagcaatggg aatattacca gagaactcac caatatcaca tttggtttca gaacaaggga
     2101 tgcaaatgta ataatattgc atgcagaaaa agagcctgaa tttcttaata ttagcattca
     2161 agattccaga ttattctttc aattgcaaag tggcaacagc ttttatatgc taagtctgac
     2221 aagtttgcag tcagtgaatg atggcacatg gcacgaagtg accctttcca tgacagaccc
     2281 actgtcccag acctccaggt ggcaaatgga agtggacaac gaaacacctt ttgtgaccag
     2341 cacaattgct actggaagcc tcaacttttt gaaggataat acagatattt atgtgggaga
     2401 cagagctatt gacaatataa agggcctgca agggtgtcta agtacaatag aaatcggagg
     2461 catttatctc tcttactttg aaaatgttca tggtttcatt aataaacctc aggaagagca
     2521 atttctcaaa atctctacca attcagtggt cactggctgt ttgcagttaa atgtctgcaa
     2581 ctccaacccc tgtttgcatg gaggaaactg tgaagacatc tatagctctt atcattgctc
     2641 ctgtcccttg ggatggtcag ggaaacactg tgaactcaac atcgatgaat gcttttcaaa
     2701 cccctgtatc catggcaact gctctgacag agttgcagcc taccactgca catgtgagcc
     2761 tggatacact ggtgtgaact gtgaagtgga tatagacaac tgccagagtc accagtgtgc
     2821 aaatggagcc acctgcatta gtcatactaa tggctattct tgcctctgtt ttggaaattt
     2881 tacaggaaaa ttttgcagac agagcagatt accctcaaca gtctgtggga atgagaagac
     2941 aaatctcact tgctacaatg gaggcaactg cacagagttc cagactgaat taaaatgtat
     3001 gtgccggcca ggttttactg gagaatggtg tgaaaaggac attgatgagt gtgcctctga
     3061 tccgtgtgtc aatggaggtc tgtgccagga cttactcaac aaattccagt gcctctgtga
     3121 tgttgccttt gctggcgagc gctgcgaggt ggacttggca gatgacttga tctccgacat
     3181 tttcaccact attggctcag tgactgtcgc cttgttactg atcctcttgc tggccattgt
     3241 tgcttctgtt gtcacctcca acaaaagggc aactcaggga acctacagcc ccagccgtca
     3301 ggagaaggag ggctcccgag tggaaatgtg gaacttgatg ccaccccctg caatggagag
     3361 actgatttag gagcattgtg tcccttcgag atggggatcc acacactgtg aatgtgatga
     3421 ctgtacttca ggtatctctg acatacctga caatgttaat ctgcaactgg gattacactg
     3481 gaactacagg aatgattcct ttgaccacct taaaaacttt cacagtggtt ccgctcgaca
     3541 ccattgtttt attatattat atcagccaat tgcaaaaaaa gtctgtgcca gtaatttcag
     3601 ccttataatt agcaaaaaca tcttccagag aataaagtct tctgtggctt tagtggctat
     3661 cactgaaact ctttcctctt ttcaacctgg gaacaaattt tagttttcat tttaggtttc
     3721 tgtactttct gtagtttctg tgtaaactgc catatgttta catggaaact acaggaaaaa
     3781 attggctaca tttctcactt ctcctatcat gtggtcaaag ttattgttgt ataccagcga
     3841 tgggatgtat acttttgtcc ttcattcatg gattcagaga aagctctggg aatgacttat
     3901 ggtccaaaaa agtgacccaa tggcaacaaa taaaaattga aatgca
//
