LOCUS       NM_207362               3873 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens CRACD like (CRACDL), mRNA.
ACCESSION   NM_207362
VERSION     NM_207362.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3873)
  AUTHORS   Alblooshi,H., Al Safar,H., El Kashef,A., Al Ghaferi,H., Shawky,M.,
            Hulse,G.K. and Tay,G.K.
  TITLE     Stratified analyses of genome wide association study data reveal
            haplotypes for a candidate gene on chromosome 2 (KIAA1211L) is
            associated with opioid use in patients of Arabian descent
  JOURNAL   BMC Psychiatry 20 (1), 41 (2020)
   PUBMED   32005204
  REMARK    GeneRIF: Stratified analyses of genome wide association study data
            reveal haplotypes for a candidate gene on chromosome 2 (KIAA1211L)
            is associated with opioid use in patients of Arabian descent.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3873)
  AUTHORS   Scott,L.J., Muglia,P., Kong,X.Q., Guan,W., Flickinger,M.,
            Upmanyu,R., Tozzi,F., Li,J.Z., Burmeister,M., Absher,D.,
            Thompson,R.C., Francks,C., Meng,F., Antoniades,A., Southwick,A.M.,
            Schatzberg,A.F., Bunney,W.E., Barchas,J.D., Jones,E.G., Day,R.,
            Matthews,K., McGuffin,P., Strauss,J.S., Kennedy,J.L., Middleton,L.,
            Roses,A.D., Watson,S.J., Vincent,J.B., Myers,R.M., Farmer,A.E.,
            Akil,H., Burns,D.K. and Boehnke,M.
  TITLE     Genome-wide association and meta-analysis of bipolar disorder in
            individuals of European ancestry
  JOURNAL   Proc Natl Acad Sci U S A 106 (18), 7501-7506 (2009)
   PUBMED   19416921
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC084377.5, BM922097.1, BC068277.1 and CF593294.1.
            
            On Nov 22, 2018 this sequence version replaced NM_207362.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC068277.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000397899.7/ ENSP00000380996.2
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-4                 AC084377.5         143413-143416       c
            5-733               BM922097.1         19-747
            734-1808            BC068277.1         724-1798
            1809-2112           CF593294.1         240-543
            2113-2474           BC068277.1         2104-2465
            2475-3873           BC068277.1         2467-3865
FEATURES             Location/Qualifiers
     source          1..3873
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q11.2"
     gene            1..3873
                     /gene="CRACDL"
                     /gene_synonym="C2orf55; KIAA1211L"
                     /note="CRACD like"
                     /db_xref="GeneID:343990"
                     /db_xref="HGNC:HGNC:33454"
     exon            1..288
                     /gene="CRACDL"
                     /gene_synonym="C2orf55; KIAA1211L"
                     /inference="alignment:Splign:2.1.0"
     exon            289..368
                     /gene="CRACDL"
                     /gene_synonym="C2orf55; KIAA1211L"
                     /inference="alignment:Splign:2.1.0"
     CDS             299..3187
                     /gene="CRACDL"
                     /gene_synonym="C2orf55; KIAA1211L"
                     /note="uncharacterized protein C2orf55; KIAA1211 like"
                     /codon_start=1
                     /product="CRACD-like protein"
                     /protein_id="NP_997245.2"
                     /db_xref="CCDS:CCDS42720.1"
                     /db_xref="GeneID:343990"
                     /db_xref="HGNC:HGNC:33454"
                     /translation="MISTRVMDIKLREAAEGLGEDSTGKKKSKFKTFKKFFGKKKRKE
                     SPSSTGSSTWKQSQTRNEVIAIESGPVGYDSEDELEESRGTLGSRALSHDSIFIPESG
                     QDATRPVRVFSQENVCDRIKALQLKIQCNVKMGPPPPPGGLPAKRGEDAGMSSEDDGL
                     PRSPPEMSLLHDVGPGTTIKVSVVSPDHVSDSTVSARISDNSLAPVADFSYPAESSSC
                     LDNSAAKHKLQVKPRNQRSSKMRRLSSRAQSESLSDLTCTPEEEENEEKPLLEVSPEE
                     RPSSGQQDVAPDRGPEPGPPAPLPPPGGARARRARLQHSSALTASVEEGGVPGEDPSS
                     RPATPELAEPESAPTLRVEPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVV
                     CAPEDVASPFPTAIPEGDTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEE
                     KGPPGPAPEPEREAETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAASEG
                     PAASPPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGA
                     ELRGAKKFSVSSCRARPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLPEPQH
                     AKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAAQEPAPSEDRNPF
                     PVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPLGTAPALRGTR
                     APSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQPAPPDAGPGEREPRKEPRTAEK
                     RPLRRGAEKSLPPAATGPGADGQPAPPWITVTRQKRRGTLDQPPNQEDKPGARTLKSE
                     PGKQAKVPERGQEPVKQADFVRSKSFLITPVKPAVDRKQGAKLNFKEGLQRGISLSHQ
                     NLAQSAVMMEKELHQLKRASYASTDQPSWMELARKKSQAWSDMPQIIK"
     exon            369..537
                     /gene="CRACDL"
                     /gene_synonym="C2orf55; KIAA1211L"
                     /inference="alignment:Splign:2.1.0"
     exon            538..673
                     /gene="CRACDL"
                     /gene_synonym="C2orf55; KIAA1211L"
                     /inference="alignment:Splign:2.1.0"
     exon            674..838
                     /gene="CRACDL"
                     /gene_synonym="C2orf55; KIAA1211L"
                     /inference="alignment:Splign:2.1.0"
     exon            839..1033
                     /gene="CRACDL"
                     /gene_synonym="C2orf55; KIAA1211L"
                     /inference="alignment:Splign:2.1.0"
     exon            1034..2714
                     /gene="CRACDL"
                     /gene_synonym="C2orf55; KIAA1211L"
                     /inference="alignment:Splign:2.1.0"
     exon            2715..2902
                     /gene="CRACDL"
                     /gene_synonym="C2orf55; KIAA1211L"
                     /inference="alignment:Splign:2.1.0"
     exon            2903..3047
                     /gene="CRACDL"
                     /gene_synonym="C2orf55; KIAA1211L"
                     /inference="alignment:Splign:2.1.0"
     exon            3048..3873
                     /gene="CRACDL"
                     /gene_synonym="C2orf55; KIAA1211L"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3854..3859
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CRACDL"
                     /gene_synonym="C2orf55; KIAA1211L"
                     /note="hexamer: AATAAA"
     polyA_site      3873
                     /gene="CRACDL"
                     /gene_synonym="C2orf55; KIAA1211L"
                     /note="major polyA site"
ORIGIN      
        1 gagcggagcc gagcgaagcc ggcgcgcctg cagctgggag ctgggagctg ggagcgcgcc
       61 gggcgcaggg ccgggccggc cgcgggaggg tagtgtcagc gcccgcgtcc agctcttcgg
      121 ccgcagaccc gggctgtctg gaggccgcgc ggccacctgc tgcgtcgccc cggctttggg
      181 ctggggctag acgcgcaccg cggcgggagc agccccggct cgccgcaccc cgcggaaggt
      241 gcccttctct gcgcgtctcg ccgagcccgg gccacgctcc tgtcccagcg agcttgacat
      301 gatttccaca agggtgatgg acattaagct tcgggaggct gcagaaggcc ttggggagga
      361 cagcacagga aagaaaaaat ctaaattcaa aacttttaag aagttttttg ggaagaagaa
      421 gagaaaagaa tcgccgtcgt ccacaggaag tagcacctgg aaacaaagtc agacgaggaa
      481 tgaggtcatt gccatcgaat ccgggccagt gggctacgac tccgaggatg agctggagga
      541 gtcgaggggc acgctgggca gccgggccct ttctcacgac agtattttca ttcctgagtc
      601 cggacaggac gctactcggc ctgtgcgggt gttttcccaa gaaaatgtgt gtgatcggat
      661 taaagctctg cagttaaaaa tacagtgtaa tgtgaaaatg gggccaccac ctcctccagg
      721 ggggcttcct gccaagcggg gagaggatgc cggcatgagc tctgaggacg acgggctgcc
      781 caggagcccc ccagagatgt ctctgctgca cgacgtgggt cctggtacca ccataaaggt
      841 ctctgtcgtg tctccagacc acgtgagcga cagcaccgtc tctgcccgga tctcagacaa
      901 cagcctggca ccagtggctg acttcagtta tcctgcagaa tcctcctcct gcctggacaa
      961 ctctgcagct aagcacaagc tccaggtcaa gccccgcaac cagcggtcga gtaagatgag
     1021 gcggctctca tcgcgcgctc agtctgaatc cctgagcgac ctgacgtgca ccccagagga
     1081 ggaggaaaac gaggagaagc cacttttgga agtcagccca gaagagcgcc ccagctctgg
     1141 gcagcaggac gtggcgccag acagaggccc tgagcctggg ccaccggcgc ccttgccgcc
     1201 acccggaggg gcccgtgcca gacgcgcccg cctgcagcac tcctccgcgc tcacggccag
     1261 cgtggaggag gggggcgtcc ccggggagga cccctcaagc cgcccggcca ccccggagct
     1321 cgccgagccc gagtcggccc ccactctccg cgtggagccc ccgtccccgc cggagggccc
     1381 cccgaatccc ggtcccgacg gcggaaagca ggatggggag gcgccccccg caggcccgtg
     1441 tgccccggcc acggacaagg cggaggaggt ggtctgtgct cccgaagacg tcgcgagccc
     1501 gtttcccacc gccatccctg agggggacac gactcccccc gagactgacc ccgccgccac
     1561 ctcagaggcg ccctctgctc gcgacgggcc agaacgcagt gtcccgaagg aagcggagcc
     1621 gacgccgccc gtgctcccgg atgaggagaa ggggccccca gggccggcgc ctgagcccga
     1681 gagagaagcg gagacggagc ccgagagagg agcggggacc gagcccgaga gaattgggac
     1741 cgagccctcc acggcgcccg ccccgagccc gccggcgccc aagagctgcc tgaaacaccg
     1801 gcccgcggcc gccagcgagg gccccgccgc gtccccgccg cttgccgctg cggagtctcc
     1861 cccggtggag cccggccccg gttccctcga cgcagaggcc gccgccccgg agcgccccaa
     1921 ggccgagcga gccgaggcgc caccggcggg cgccgagagg gcggcgccag agcggaaggc
     1981 ggagaggggc ggtgccgagc tgcgaggcgc gaagaagttc tcggtgtcct cgtgccgagc
     2041 gcggcctcgt ccgggcgtct cccgcccgct ggaacgggcc agcggccgcc tgcccctcgc
     2101 gaggagcggc ccggtctgga ggagcgaggc ggctcttgac gacctccagg gtctccccga
     2161 gccccagcac gcgaaacctg gccctcggaa gctggcggag cgcggccctc aggactcggg
     2221 ggacagggcg gccagcccgg ccgggccgcg caagagccct caggaggcgg ccgccgcgcc
     2281 cggcacgaga gagccctgcc cagccgccca ggagccggcc ccgagtgagg acagaaaccc
     2341 cttccccgtc aagctccggt ccacctccct ctcgctcaaa tacagggatg gcgcctctca
     2401 ggaggtgaag ggtgtgaaga ggtacagtgc cgaggtccgg ttagaaaggt cgctgaccgt
     2461 gctcccgaag gaggagaagt gtcccctcgg gacggccccc gcccttcgag gcaccagggc
     2521 ccccagcgac caaggaaagg ggaaggcccg gccccccgag ccgctcagct ccaagccgcc
     2581 cctgccccgg aagccgcttc tgcagagctt cacgctcccg caccagcccg cgccccccga
     2641 cgccggcccg ggagagcggg aacccaggaa ggagcccagg acggcggaga aaaggccgct
     2701 gcgcagggga gctgaaaaga gtctgccgcc tgcagcaaca gggcctggag ctgatgggca
     2761 gcctgcgcca ccctggatca ccgtcactcg gcagaagcgg agggggacct tggaccagcc
     2821 acccaaccag gaagacaagc ctggggcacg gaccctgaag tctgaaccag gaaagcaagc
     2881 caaggtgccc gagagaggcc aggagcctgt gaagcaagct gactttgttc gcagcaagtc
     2941 tttcctgata acccctgtga agcccgctgt ggaccggaag cagggggcaa agctcaactt
     3001 caaggagggg ctgcaaagag gaatctcatt gtcccatcag aacttggctc agtctgcagt
     3061 gatgatggag aaggaactgc atcagctgaa gagagccagt tatgccagta cagatcagcc
     3121 atcctggatg gaacttgcca gaaagaaatc tcaagcttgg agtgacatgc cccagattat
     3181 aaaataggtg ggcagtgtgc tgataaagca tgtccactac cctgacaagc cacttagtta
     3241 aaaactgcca gtgtattgtg gcaaacaaac tgtgaaactt aaagattgat tttatcatca
     3301 agttatgacg aacttgggga agaggaagga accaggcaaa acaaagagga taaacacaca
     3361 gccatactcc tgggccagag ggcccagaaa caagaacaac attgaaaaag tccaggaacc
     3421 agttcctgtg cccaaaggta cgaatgtgtc ttttcgaatt cccttgataa agaagcctca
     3481 gacaaggaag aaaatagaaa tgaaattgga cacataaata ggacacccag caaaggccag
     3541 aagagaagcc cttctaggag aagggacatc tgtgcttcca gctgagatca gcccatgtct
     3601 ctggtcgctc tcttgcctgt ggatcctgtc ttctttcatg tttactacga ggcatgacat
     3661 tcatggcaaa acagggatgc cgtttccaag agcagctata aaacaatctg ttttcctaaa
     3721 gacagccact ctgagaagga gatgaaggaa cacggcaggg ttcatcaatt catagactgt
     3781 ttccaaaaat aatttttaaa cttttccact aggcatctgt gtctttaacc actgcacaat
     3841 gcattgcctg tttaataaaa ggtttcaaac atg
//
