LOCUS       XM_005268590            6587 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens cleavage and polyadenylation specific
            factor 6 (CPSF6), transcript variant X3, mRNA.
ACCESSION   XM_005268590
VERSION     XM_005268590.4
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000012.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_005268590.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6587
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
     gene            1..6587
                     /gene="CPSF6"
                     /gene_synonym="CFIM; CFIM68; CFIM72; HPBRII-4; HPBRII-7"
                     /note="cleavage and polyadenylation specific factor 6;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 3 mRNAs, 50 ESTs, 3576 long SRA reads, 6
                     Proteins, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 160 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:11052"
                     /db_xref="HGNC:HGNC:13871"
                     /db_xref="MIM:604979"
     CDS             79..1737
                     /gene="CPSF6"
                     /gene_synonym="CFIM; CFIM68; CFIM72; HPBRII-4; HPBRII-7"
                     /codon_start=1
                     /product="cleavage and polyadenylation specificity factor
                     subunit 6 isoform X2"
                     /protein_id="XP_005268647.1"
                     /db_xref="GeneID:11052"
                     /db_xref="HGNC:HGNC:13871"
                     /db_xref="MIM:604979"
                     /translation="MADGVDHIDIYADVGEEFNQEAEYGGHDQIDLYDDVISPSANNG
                     DAPEDRDYMDTLPPTVGDDVGKGAAPNVVYTYTGKRIALYIGNLTWWTTDEDLTEAVH
                     SLGVNDILEIKFFENRANGQSKGFALVGVGSEASSKKLMDLLPKRELHGQNPVVTPCN
                     KQFLSQFEMQSRKTTQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFP
                     GPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPP
                     VLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPP
                     LTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDR
                     GDYGPPGREMDTARTPLSEAEFEEIMNRNRAISSSAISRAVSDASAGDYGSAIETLVT
                     AISLIKQSKVSADDRCKVLISSLQDCLHGIESKSYGSGSRRRERSRERDHSRSREKSR
                     RHKSRSRDRHDDYYRERSRERERHRDRDRDRDRERDREREYRHR"
ORIGIN      
        1 gctagatccg ctgctgctgc cgcggcgggc agacctgcag gaggcggcgg cggcggcggc
       61 ggccgaggct gaaggaagat ggcggacggc gtggaccaca tagacattta cgcggatgtc
      121 ggcgaagagt tcaaccagga agctgaatat ggtgggcatg atcagataga tttgtatgac
      181 gatgtcatat ctccatctgc aaataatgga gatgccccag aagaccgaga ttacatggat
      241 actctcccac caactgttgg tgatgatgtg ggtaaaggag cagcaccaaa tgttgtctat
      301 acatatactg gaaagagaat tgcattatat attggaaatc taacatggtg gacaacagat
      361 gaagacttaa ctgaagcagt tcattctttg ggagtaaatg atattttgga gataaaattt
      421 tttgaaaatc gggcaaatgg ccagtcaaag gggtttgccc ttgttggtgt tggatctgaa
      481 gcatcttcaa aaaagttaat ggatctgtta cctaaaagag aacttcatgg tcagaatcct
      541 gttgtaactc catgcaataa acagttcctg agtcaatttg aaatgcagtc caggaaaact
      601 acacaatcag gacaaatgtc tggggaaggt aaagctggtc ctccaggagg cagttcccgt
      661 gcagcatttc cacaaggtgg tagaggacgg ggccgttttc caggggctgt tcctggtggg
      721 gacagatttc ctgggccagc aggaccagga gggccacccc caccttttcc agctggacag
      781 actccaccac gtccaccctt aggtcctcca ggcccacctg gtccaccagg tcctccacct
      841 cctggtcagg ttctgcctcc tcctctagct gggcctccta atcgaggaga tcgccctcca
      901 ccaccagttc tttttcctgg acaacctttt gggcagcctc cattgggtcc acttcctcct
      961 ggccctccac ctccagttcc aggctacggc ccccctcctg gcccaccacc tccacaacag
     1021 ggaccacctc cacctccagg cccctttcca cctcgtccac ccggtccact tgggccaccc
     1081 cttacactag ctcctcctcc gcatcttcct ggaccacctc caggtgcccc accgccagct
     1141 ccgcatgtga acccagcttt ctttcctcca ccaactaaca gtggcatgcc tacatcagat
     1201 agccgaggtc caccaccaac agatccatat gggcgacctc caccatatga taggggtgac
     1261 tatggccccc ctggaaggga aatggatact gcaagaacgc cattgagtga agctgaattt
     1321 gaagaaatca tgaatagaaa tagggcaatc tcaagcagtg ctatttcgag agctgtgtct
     1381 gatgccagtg ctggtgatta tgggagtgct attgagacac tggtaactgc aatttcttta
     1441 attaaacaat ccaaagtatc tgctgatgat cgttgcaaag ttcttattag ttctttgcaa
     1501 gattgccttc atggaattga gtccaagtct tatggttctg gatcaagaag acgtgaacga
     1561 tcaagagaga gggaccatag tagatcacga gaaaagagtc gacgtcataa atcccgtagt
     1621 agagaccgtc atgacgatta ttacagagag agaagcagag aacgagagag gcaccgggat
     1681 cgtgaccgag accgtgaccg agagcgtgac cgagagcgcg aatatcgtca tcgttagaag
     1741 ctgaaggaag aggatcacct tccaagacaa aacagtcttc atgggggaaa aatgacgctt
     1801 gtccagcagt ttgcttcttg tgattgaact gaacctgtaa ggattcatgg ataaaatgaa
     1861 caggaataga tctgaataaa gcaaatctgc ataaatggta accagtagct ctacttttat
     1921 tttttatgtt gcttaactgt tttatttgaa ggaaacctgt gtgatttaaa aagttatagc
     1981 ttttgcaact ttattactgg ttatatacat ttggccatta tgatgtgcaa gcaattggaa
     2041 aaaaagtcaa gtaaatgctt gtttttgtag tagtttgttc ttgttaaaaa tgtttatatg
     2101 ataatgtctg taaacagcat cactttgatt acaatagatg tagtgttgta ataaactgtt
     2161 taatggggct gatgtgtaaa gctgttcaag ttatttgatg tttacacctc agggaaagtc
     2221 ttgtgttcag caatatctaa agataatgtt actatgacaa catttttact gtcctttaaa
     2281 gcattgcaat agcgtttttg gatatgcctc aatctaatct tgcgttcagt gaattaaaca
     2341 tagtaattaa gtgtcttttg cccttgattt tgatattaga ataggtgatt acatggatat
     2401 ttaatatttc tatattctgc ttttctagct gtttttacct agttagcttg tgactttgct
     2461 gaatggtatg taaacttgta aaaatagaga tttgacagac atagcaatct agtcaatgtg
     2521 taaggggtca aaaaaacaga ggttttaaca cataagtaaa aacccgtaca tatttgatgt
     2581 gtaatgcagg ttaattacaa cacagatgta ccgaaacact taattgtgaa ccgctaacat
     2641 tgaagaaatt ttgacaattc cgatttgatg ctgcaattac ttgctgtttt tattgatctt
     2701 atggtttatt tcttaagcca tagtcagtgt aaatacagcc ctgcagcagg taaatgtgag
     2761 taaagagagc cttatatttt ccaattggta taaatttttg aaggatgtga tgttcattaa
     2821 cattcggttg tattccccag tatttgtaat gggaaattac agataaaccg tgtctgcaca
     2881 gtttaaggaa tactatgtat attcatgcac cgtattgatt catgctatag ttacttaatc
     2941 aaagattttt ttcaaacctg ccttacatat aggcccactt taaaagcacc tgactagcat
     3001 gtgttcttga ttgcaaaatt ggcagaggca gggtgtcaac ttgattaggt gtttttatgg
     3061 gaatgtaatt tgaaatcact acttcagaaa tttgacttaa aattcttgag cacgttaata
     3121 tgtttttaag atctgattat ctttgagaga tcttctgtta atacacattg gttgttaaag
     3181 agtacccaaa ttctaggaca atgcttaaag tgttaaaata ccctagatac tgtgttatgt
     3241 gcaactgtag aaaccctcca gaaatttcca ctgctgttct tcactttcat cttgtctgct
     3301 atcaaaccac ttctgacaaa attagctgtt ttgaattacc catatcactg ccagttttat
     3361 tttaaaatat tttgtgtttg aagtatctgt gcatgggatc gttgatgttt atcagaactg
     3421 ttcactttca gaaatgattt tttaaagcat tttgttgaaa atgcggttgc ttttttaaca
     3481 ttattttaga gttgtatcaa aattttcctg ttttctgtat attgttgtgt catttcttgg
     3541 ctttttaata ttttgactac aatgccctaa tgcgaagaag tatggacata taaatattac
     3601 aagagaaatt agttaatagt aaagggttaa aaggtaagta aaatgtccat gaaaataaaa
     3661 ttttctttga acagtttaaa aatggaatca caaaaatcta actgcacttg aaatgaaact
     3721 ggaaatttta tactaattaa atcctttatt taccttttca tattttatca atggaacctt
     3781 ttaattgctc cttctatatc actcttctcc ttgcttggct gatctcatta catgactttc
     3841 gttacagaca gtgtgagtgt actagatttg tttgctgcta atccgttatt ttaagtgttg
     3901 tcagaaggaa ataacttctt ggtttgacca agtaattttg caaagtcctt ctctacctga
     3961 taacacgtga atgtatagca gtaaaggtga aaattgcagg ccttgttttg ttcttcatac
     4021 ccccttcagt tgtttatggg ttaatgttat ttgaaaactc ttcctttttt taatgtgtaa
     4081 aaacaatcca aagagataaa tccttgcata gacaccaaaa acagtgtctc agagaccttt
     4141 tcattttttc cttagttaat aactgtagtg gatgtgaaaa caaacgagtt gaattttaaa
     4201 acatagcatt tattagtgct atacagtcac attcctttca gccagtagta aagttaaaca
     4261 gatgagtgat acagtacctg aatggtactg cttctgaggc aacactttgg attgaaagtg
     4321 ctgcttttgg ttaaaggaac tatgttgtgg aaagcatatt ccagtgtaaa tttgcagatg
     4381 tgtgtttttt ttttttgtca cttttcataa ggtttggagt aagttgcagt ggcttttgat
     4441 catagtttag cccatttaat ggtcctttta cctagaatgt tcttaagcag ttaatgacaa
     4501 tttggaatac acagataact tgtagcttaa gatactattt tcatttaatt ctcctgtgga
     4561 gaatattgct ttatttttta ctagtttcag gtcagttatt aaaataaaca tggaggtttt
     4621 aatgaatgtt gtataatatt ttatagtgaa ggaaaattgt ggaaagggca aagactttct
     4681 ctttccctta tgtatttaac tgtgccaatc taaatacata ctgttttata caatgagatg
     4741 cattacaaga cttttctgtt ggagtgctct cgacattttg gttttcatac ctgaatgatc
     4801 attgcatttt ctgtattttc taaaatggct ccaattttgt gttttaagct tcagcttaag
     4861 aggaagttta tgttctaatt cttgactgag aatacagtat tgagattctc tgttttacag
     4921 ataacaactg gtttttatta ctcattaagt tcatttgcat cccgtagccc tctgtaaatg
     4981 tttcccctag ttgtatgtac gtaaatgcac gcttatccag tgtatattag acatttttgt
     5041 gctaaaatat attaagtggg atttttgtag caaagcattc tatttttctg ttcttacagt
     5101 gtgtgtgtgt gtgtgtgtgt gtgtgtatgc gtttttttaa ccttaacttc agtttaaaca
     5161 ctggtgtatt tattttttta agcaacttga ctcttagaag ccttagactg attttttcaa
     5221 taaatattca accaaaaatt ataaatttat taagatgtgg ccttacatat ggcattcctt
     5281 gtgttcgtaa tgtgagattt ttgatttaga taaatcaaga ttcaggatta aagtttcatt
     5341 gtaagttgaa atagaaaatg tattaaaatg tctaggcttc tgggaggaag ttcttatact
     5401 cttctttctt ggcattagaa agaagcaata tgaatttttg tgaatattct aaatattcag
     5461 gcaacactgt tcagattgat ttaggtttgt cttaaccaat gttctttttt tagaatttca
     5521 ggttgtggca ttcactgagt atgcagctac tatggttttt gtatgggacg tataaatact
     5581 tgattatata cgacagattt taatgtcttt aaagacttcc tgctgtatta acatattgta
     5641 atggagtctt ttaaatacta ggttgaattt aattgaagtc acacacatct tgaagtggta
     5701 actgcatagt aaatactacc aagagttttt ttcacgtggg agtatcctaa aactctgcca
     5761 tgggtgtaaa tgttttacat taatttcata attggacaga ccctgcattt agcgaaaaca
     5821 ttttgttttg aaagtgtgtt ctttttgtcg cactgttact gcgtaacact tctcaacatt
     5881 ctgtaagtta aattatttta aaataactat ggtgaattca tgtttatttt tttactttga
     5941 aaattgtagt actcaggtgg tatttaatgg gaaaggatcc tttgggtata aatcataatg
     6001 tattttaagg aatgcatcta taacattgat aactttagcc ttaaaaaaaa ggtctattat
     6061 tccttcctct gcatcccatg gtatattagc aaagtagttt acagccctgt acagccttac
     6121 aaagttgttt tacaattttt aatggaaagc ccttaacaac aacaacaaaa aattgtatca
     6181 ttttaccaat atccacgaat tactgatcac agtttgtaaa taatttgttt aatatcagaa
     6241 ggccaaagaa agtcttaaaa ttttagctat tgactctatg gtgacttcac aataagattt
     6301 ctgtgcaaaa aggtaaggtg ataattgatc taatagactt tttttttttt ttttttgctg
     6361 tccatgagaa ttagacttca tattagcttc aattaaaaag ctcattccat tttattaaaa
     6421 tgtttgtaat tgcaattttg tgtttaatgt ttactttgtc tttcctttct ttagcattta
     6481 ggtgactgtt cggcagtttg atatatggcc attgtcggcc ttaaactgca ctagtaacaa
     6541 gcatggtatt tatcttgtat tgaaaataaa acaaactttt gataaga
//
