LOCUS       XM_047421735            4525 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens cleavage and polyadenylation specific
            factor 1 (CPSF1), transcript variant X5, mRNA.
ACCESSION   XM_047421735
VERSION     XM_047421735.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000008.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4525
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="8"
     gene            1..4525
                     /gene="CPSF1"
                     /gene_synonym="CPSF160; HSU37012; MYP27; P/cl.18"
                     /note="cleavage and polyadenylation specific factor 1;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 2 mRNAs, 149 ESTs, 1400 long SRA reads, 1
                     Protein, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 84 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:29894"
                     /db_xref="HGNC:HGNC:2324"
                     /db_xref="MIM:606027"
     CDS             341..4438
                     /gene="CPSF1"
                     /gene_synonym="CPSF160; HSU37012; MYP27; P/cl.18"
                     /codon_start=1
                     /product="cleavage and polyadenylation specificity factor
                     subunit 1 isoform X2"
                     /protein_id="XP_047277691.1"
                     /db_xref="GeneID:29894"
                     /db_xref="HGNC:HGNC:2324"
                     /db_xref="MIM:606027"
                     /translation="MSMASVQLAGAKRDALLLSFKDAKLSVVEYDPGTHDLKTLSLHY
                     FEEPELRDGFVQNVHTPRVRVDPDGRCAAMLVYGTRLVVLPFRRESLAEEHEGLVGEG
                     QRSSFLPSYIIDVRALDEKLLNIIDLQFLHGYYEPTLLILFEPNQTWPGRVAVRQDTC
                     SIVAISLNITQKVHPVIWSLTSLPFDCTQALAVPKPIGGVVVFAVNSLLYLNQSVPPY
                     GVALNSLTTGTTAFPLRTQEGVRITLDCAQATFISYDKMVISLKGGEIYVLTLITDGM
                     RSVRAFHFDKAAASVLTTSMVTMEPGYLFLGSRLGNSLLLKYTEKLQEPPASAVREAA
                     DKEEPPSKKKRVDATAGWSAAGKSVPQDEVDEIEVYGSEAQSGTQLATYSFEVCDSIL
                     NIGPCANAAVGEPAFLSEEFQNSPEPDLEIVVCSGHGKNGALSVLQKSIRPQVVTTFE
                     LPGCYDMWTVIAPVRKEEEDNPKGEGTEQEPSTTPEADDDGRRHGFLILSREDSTMIL
                     QTGQEIMELDTSGFATQGPTVFAGNIGDNRYIVQVSPLGIRLLEGVNQLHFIPVDLGA
                     PIVQCAVADPYVVIMSAEGHVTMFLLKSDSYGGRHHRLALHKPPLHHQSKVITLCLYR
                     DLSGMFTTESRLGGARDELGGRSGPEAEGLGSETSPTVDDEEEMLYGDSGSLFSPSKE
                     EARRSSQPPADRDPAPFRAEPTHWCLLVRENGTMEIYQLPDWRLVFLVKNFPVGQRVL
                     VDSSFGQPTTQGEARREEATRQGELPLVKEVLLVALGSRQSRPYLLVHVDQELLIYEA
                     FPHDSQLGQGNLKVRFKKVPHNINFREKKPKPSKKKAEGGGAEEGAGARGRVARFRYF
                     EDIYGYSGVFICGPSPHWLLVTGRGALRLHPMAIDGPVDSFAPFHNVNCPRGFLYFNR
                     QGELRISVLPAYLSYDAPWPVRKIPLRCTAHYVAYHVESKVYAVATSTNTPCARIPRM
                     TGEEKEFETIERDERYIHPQQEAFSIQLISPVSWEAIPNARIELQEWEHVTCMKTVSL
                     RSEETVSGLKGYVAAGTCLMQGEEVTCRGRILIMDVIEVVPEPGQPLTKNKFKVLYEK
                     EQKGPVTALCHCNGHLVSAIGQKIFLWSLRASELTGMAFIDTQLYIHQMISVKNFILA
                     ADVMKSISLLRYQEESKTLSLVSRDAKPLEVYSVDFMVDNAQLGFLVSDRDRNLMVYM
                     YLPEAKESFGGMRLLRRADFHVGAHVNTFWRTPCRGATEGLSKKSVVWENKHITWFAT
                     LDGGIGLLLPMQEKTYRRLLMLQNALTTMLPHHAGLNPRAFRMLHVDRRTLQNAVRNV
                     LDGELLNRYLYLSTMERSELAKKIGTTPDIILDDLLETDRVTAHF"
ORIGIN      
        1 gaacaccaca gaagaggcaa acagcagccc catcagcttt caggaggcgg cggaggcctt
       61 tgcctcatga ctggatgctg atgctttgat gcttggttgg gtagtgttgg cctggattcc
      121 cccactcatg gtaagtttag cgatggctgt tcttgcggaa atctagtttt gcgttcctgg
      181 aataactcaa cccagttgtg ttacaatacc cctgcttgtc actgggctca tctgcaggcg
      241 ttttgaggag gctctgacca agaatgacag gagcacagag gggaaggccc accgggagaa
      301 gctcgagctt gctgcctcct tctccttctt tggcaacgtc atgtccatgg ccagcgtgca
      361 gctggcagga gccaagcggg atgccctgct cctaagcttc aaggatgcca agctgtctgt
      421 ggtggagtac gacccgggca cccatgacct gaagaccctg tcactgcact actttgagga
      481 gcctgagctt cgggacgggt ttgtgcagaa tgtacacacg ccgcgagtgc gggtggaccc
      541 cgacgggcgc tgtgcagcca tgcttgtcta cggcacgcgg ctggtggtcc tgcccttccg
      601 cagggagagc ctggctgagg agcacgaggg gctcgtgggt gaggggcaga ggtccagctt
      661 cctgcccagc tacatcatcg acgtgcgggc cctagacgag aagctgctca acatcatcga
      721 cctgcagttc ctgcatggct actacgagcc taccctcctc atcctgtttg agcccaacca
      781 gacctggcct gggcgcgtgg ccgtgcggca ggacacgtgc tccattgtgg ccatctcact
      841 gaacatcacg cagaaggtgc accccgtcat ctggtccctc accagcctgc cctttgactg
      901 cacccaggct ctggctgtgc ccaagcccat aggtggggtg gtggtgtttg ccgtcaactc
      961 gctgttgtac ctgaaccaga gcgtcccccc gtatggcgtg gctctcaaca gcctcaccac
     1021 aggaaccacg gctttcccgc ttcgcaccca ggagggtgtg cggatcaccc tggactgcgc
     1081 ccaggccacc ttcatctcct acgacaagat ggtcatctcc ctcaagggcg gcgagatcta
     1141 cgtgctgacc ctcatcaccg acggcatgcg cagtgtccga gcgttccact ttgacaaggc
     1201 ggccgccagc gtcctcacca ccagcatggt caccatggag cccgggtacc tgttcctggg
     1261 ttctcgcctg ggcaattccc tcctcctcaa gtacacggag aagctgcagg agcccccggc
     1321 cagtgctgtc cgtgaggctg ccgacaagga agagcctccc tcaaagaaga agcgagtgga
     1381 tgcgacggcc ggctggtcag ctgcgggtaa gtcggtgccg caggatgagg tggacgagat
     1441 tgaagtgtac ggcagcgagg cccagtcggg aacacagctg gccacctact cctttgaggt
     1501 gtgtgacagc atcctgaaca ttggaccctg tgccaatgcc gccgtgggcg agcctgcctt
     1561 cctctctgaa gagtttcaga acagccccga gccggacctg gagattgtgg tttgctccgg
     1621 ccacgggaag aacggggctt tgtcggtgct gcagaagagc atccggcccc aggtggtgac
     1681 aacctttgag cttcccggct gctatgacat gtggacagtc atcgccccgg tgcgtaagga
     1741 ggaggaggac aatcccaagg gggagggcac agagcaggaa cccagcacca cccctgaagc
     1801 agacgacgac ggccgcagac acggattcct gattctgagc cgggaagact ccaccatgat
     1861 cctgcagacg gggcaggaga tcatggagct ggacaccagt ggcttcgcca ctcagggccc
     1921 cacggtcttt gctgggaaca tcggggacaa ccgctacatt gtccaagtgt caccactggg
     1981 catccgcctg ctggaaggag tgaatcagct gcacttcatc cccgtggacc tgggcgcccc
     2041 catcgtgcag tgcgccgtgg ccgaccccta tgtggtcatc atgagtgccg agggccacgt
     2101 caccatgttc ctgctgaaga gtgactccta cggtggccgc caccaccgcc tggcgctgca
     2161 caagcccccg ctgcaccatc agtccaaggt gattacgctg tgcctgtacc gagacctcag
     2221 cggcatgttc accactgaga gccgcctggg tggggcccgt gacgagctcg ggggccgcag
     2281 tggcccggag gccgagggcc tgggctcaga gactagcccc acagtggatg acgaggagga
     2341 gatgctgtat ggggattcgg gctccctctt cagccccagc aaggaggagg cccgaagaag
     2401 cagccagccc cctgctgacc gggaccctgc acccttccgg gcagagccta cccactggtg
     2461 cctgctggtg cgggagaatg gcaccatgga gatctaccag cttcccgact ggcggctggt
     2521 gttcctggtg aagaacttcc ctgtggggca gcgggtcctt gtggacagct cctttggaca
     2581 gcccactaca cagggcgagg cccgcaggga ggaggccacg cgccaggggg agctgcccct
     2641 cgtcaaggag gtgctgctgg tggcgctggg cagccgccag agcaggccct acctgctggt
     2701 gcatgtggac caagagctgc ttatctacga ggccttcccc cacgactctc agctcggcca
     2761 gggcaatctc aaagtccgct ttaagaaggt ccctcacaac atcaacttcc gtgagaagaa
     2821 gccaaagcca tccaagaaga aagcagaagg tggcggcgca gaggaggggg ctggggcccg
     2881 gggccgcgtg gcgcgtttcc gctacttcga ggatatttat ggctactcag gggtcttcat
     2941 ctgcggcccc tcccctcact ggctcttggt gaccggccga ggggctctgc ggctacaccc
     3001 catggccatc gacggcccgg tcgactcttt cgctccattc cacaatgtca actgtccccg
     3061 cggcttcctg tacttcaaca gacagggcga gctgaggatc agtgtcctgc ctgcctacct
     3121 gtcctatgat gccccatggc ctgtcaggaa gatcccgctg cgctgcacgg cccactatgt
     3181 ggcttaccac gtggagtcta aggtgtatgc tgtggccacc agcaccaaca cgccgtgtgc
     3241 ccgcatccca cgcatgactg gcgaggagaa ggagtttgag accatcgaga gagatgagcg
     3301 gtacatccac ccccagcagg aggccttctc catccagctc atctccccgg tcagctggga
     3361 ggctattccc aatgccagga tcgagctgca ggagtgggag catgtgacct gcatgaagac
     3421 agtgtctctg cgcagtgagg agaccgtgtc gggcctcaaa ggctacgtgg ccgccgggac
     3481 ctgcctcatg cagggggagg aggtcacgtg ccgagggcgg atcttgatca tggatgtgat
     3541 tgaggtggtg cccgagcctg gccagccctt gaccaagaac aagttcaaag tcctttacga
     3601 gaaggagcag aaggggcccg tgaccgccct gtgccactgc aatggccacc tggtgtcggc
     3661 catcggccag aagattttcc tgtggagcct gcgggccagc gagctgacgg gcatggcctt
     3721 catcgacacg cagctctaca tacaccagat gatcagcgtc aagaacttca tcctggcagc
     3781 cgacgtcatg aagagcattt cgctgctgcg ctaccaggag gaaagcaaga cgctgagcct
     3841 ggtgtcgcgg gatgccaagc ccctggaggt gtacagcgtg gacttcatgg tggacaatgc
     3901 ccagctgggt tttctggtgt ctgaccgcga ccgcaacctc atggtgtaca tgtacctgcc
     3961 cgaagccaag gagagtttcg ggggcatgcg cctgctgcgt cgggcagact tccacgtggg
     4021 tgcccacgtg aacacgttct ggaggacccc gtgccggggg gccactgaag ggctcagcaa
     4081 aaagtcggtc gtgtgggaga ataagcacat cacgtggttt gccaccctgg acggcggcat
     4141 cgggctgctg ctgcccatgc aggagaagac ctaccggcgg ctgctgatgc tgcagaacgc
     4201 gctgaccacc atgctgccac accacgccgg cctcaacccc cgcgccttcc ggatgctgca
     4261 cgtggaccgc cgcaccctcc agaatgccgt gcgcaacgtg ctggatgggg agctgctcaa
     4321 ccgctacctg tacctgagca ccatggagcg cagcgagcta gccaagaaga tcggcaccac
     4381 accagacata atcctggacg acttgctgga gacggaccgc gtcaccgccc acttctagcc
     4441 ccgtggatgc cgtcaccacc agcacacgga actacctccc accccctttt tgtacaaaac
     4501 acaaggaaaa acattttttg cttga
//
