LOCUS       XM_047421734            4530 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens cleavage and polyadenylation specific
            factor 1 (CPSF1), transcript variant X4, mRNA.
ACCESSION   XM_047421734
VERSION     XM_047421734.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000008.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4530
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="8"
     gene            1..4530
                     /gene="CPSF1"
                     /gene_synonym="CPSF160; HSU37012; MYP27; P/cl.18"
                     /note="cleavage and polyadenylation specific factor 1;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 2 mRNAs, 149 ESTs, 1402 long SRA reads, 1
                     Protein, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 72 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:29894"
                     /db_xref="HGNC:HGNC:2324"
                     /db_xref="MIM:606027"
     CDS             346..4443
                     /gene="CPSF1"
                     /gene_synonym="CPSF160; HSU37012; MYP27; P/cl.18"
                     /codon_start=1
                     /product="cleavage and polyadenylation specificity factor
                     subunit 1 isoform X2"
                     /protein_id="XP_047277690.1"
                     /db_xref="GeneID:29894"
                     /db_xref="HGNC:HGNC:2324"
                     /db_xref="MIM:606027"
                     /translation="MSMASVQLAGAKRDALLLSFKDAKLSVVEYDPGTHDLKTLSLHY
                     FEEPELRDGFVQNVHTPRVRVDPDGRCAAMLVYGTRLVVLPFRRESLAEEHEGLVGEG
                     QRSSFLPSYIIDVRALDEKLLNIIDLQFLHGYYEPTLLILFEPNQTWPGRVAVRQDTC
                     SIVAISLNITQKVHPVIWSLTSLPFDCTQALAVPKPIGGVVVFAVNSLLYLNQSVPPY
                     GVALNSLTTGTTAFPLRTQEGVRITLDCAQATFISYDKMVISLKGGEIYVLTLITDGM
                     RSVRAFHFDKAAASVLTTSMVTMEPGYLFLGSRLGNSLLLKYTEKLQEPPASAVREAA
                     DKEEPPSKKKRVDATAGWSAAGKSVPQDEVDEIEVYGSEAQSGTQLATYSFEVCDSIL
                     NIGPCANAAVGEPAFLSEEFQNSPEPDLEIVVCSGHGKNGALSVLQKSIRPQVVTTFE
                     LPGCYDMWTVIAPVRKEEEDNPKGEGTEQEPSTTPEADDDGRRHGFLILSREDSTMIL
                     QTGQEIMELDTSGFATQGPTVFAGNIGDNRYIVQVSPLGIRLLEGVNQLHFIPVDLGA
                     PIVQCAVADPYVVIMSAEGHVTMFLLKSDSYGGRHHRLALHKPPLHHQSKVITLCLYR
                     DLSGMFTTESRLGGARDELGGRSGPEAEGLGSETSPTVDDEEEMLYGDSGSLFSPSKE
                     EARRSSQPPADRDPAPFRAEPTHWCLLVRENGTMEIYQLPDWRLVFLVKNFPVGQRVL
                     VDSSFGQPTTQGEARREEATRQGELPLVKEVLLVALGSRQSRPYLLVHVDQELLIYEA
                     FPHDSQLGQGNLKVRFKKVPHNINFREKKPKPSKKKAEGGGAEEGAGARGRVARFRYF
                     EDIYGYSGVFICGPSPHWLLVTGRGALRLHPMAIDGPVDSFAPFHNVNCPRGFLYFNR
                     QGELRISVLPAYLSYDAPWPVRKIPLRCTAHYVAYHVESKVYAVATSTNTPCARIPRM
                     TGEEKEFETIERDERYIHPQQEAFSIQLISPVSWEAIPNARIELQEWEHVTCMKTVSL
                     RSEETVSGLKGYVAAGTCLMQGEEVTCRGRILIMDVIEVVPEPGQPLTKNKFKVLYEK
                     EQKGPVTALCHCNGHLVSAIGQKIFLWSLRASELTGMAFIDTQLYIHQMISVKNFILA
                     ADVMKSISLLRYQEESKTLSLVSRDAKPLEVYSVDFMVDNAQLGFLVSDRDRNLMVYM
                     YLPEAKESFGGMRLLRRADFHVGAHVNTFWRTPCRGATEGLSKKSVVWENKHITWFAT
                     LDGGIGLLLPMQEKTYRRLLMLQNALTTMLPHHAGLNPRAFRMLHVDRRTLQNAVRNV
                     LDGELLNRYLYLSTMERSELAKKIGTTPDIILDDLLETDRVTAHF"
ORIGIN      
        1 gaacaccaca gaagaggcaa acagcagccc catcagcttt caggaggcgg cggaggcctt
       61 tgcctcatga ctggatgctg atgctttgat gcttggttgg gtagtgttgg cctggattcc
      121 cccactgtaa gcatggtaag tttagcgatg gctgttcttg cggaaatcta gttttgcgtt
      181 cctggaataa ctcaacccag ttgtgttaca atacccctgc ttgtcactgg gctcatctgc
      241 aggcgttttg aggaggctct gaccaagaat gacaggagca cagaggggaa ggcccaccgg
      301 gagaagctcg agcttgctgc ctccttctcc ttctttggca acgtcatgtc catggccagc
      361 gtgcagctgg caggagccaa gcgggatgcc ctgctcctaa gcttcaagga tgccaagctg
      421 tctgtggtgg agtacgaccc gggcacccat gacctgaaga ccctgtcact gcactacttt
      481 gaggagcctg agcttcggga cgggtttgtg cagaatgtac acacgccgcg agtgcgggtg
      541 gaccccgacg ggcgctgtgc agccatgctt gtctacggca cgcggctggt ggtcctgccc
      601 ttccgcaggg agagcctggc tgaggagcac gaggggctcg tgggtgaggg gcagaggtcc
      661 agcttcctgc ccagctacat catcgacgtg cgggccctag acgagaagct gctcaacatc
      721 atcgacctgc agttcctgca tggctactac gagcctaccc tcctcatcct gtttgagccc
      781 aaccagacct ggcctgggcg cgtggccgtg cggcaggaca cgtgctccat tgtggccatc
      841 tcactgaaca tcacgcagaa ggtgcacccc gtcatctggt ccctcaccag cctgcccttt
      901 gactgcaccc aggctctggc tgtgcccaag cccataggtg gggtggtggt gtttgccgtc
      961 aactcgctgt tgtacctgaa ccagagcgtc cccccgtatg gcgtggctct caacagcctc
     1021 accacaggaa ccacggcttt cccgcttcgc acccaggagg gtgtgcggat caccctggac
     1081 tgcgcccagg ccaccttcat ctcctacgac aagatggtca tctccctcaa gggcggcgag
     1141 atctacgtgc tgaccctcat caccgacggc atgcgcagtg tccgagcgtt ccactttgac
     1201 aaggcggccg ccagcgtcct caccaccagc atggtcacca tggagcccgg gtacctgttc
     1261 ctgggttctc gcctgggcaa ttccctcctc ctcaagtaca cggagaagct gcaggagccc
     1321 ccggccagtg ctgtccgtga ggctgccgac aaggaagagc ctccctcaaa gaagaagcga
     1381 gtggatgcga cggccggctg gtcagctgcg ggtaagtcgg tgccgcagga tgaggtggac
     1441 gagattgaag tgtacggcag cgaggcccag tcgggaacac agctggccac ctactccttt
     1501 gaggtgtgtg acagcatcct gaacattgga ccctgtgcca atgccgccgt gggcgagcct
     1561 gccttcctct ctgaagagtt tcagaacagc cccgagccgg acctggagat tgtggtttgc
     1621 tccggccacg ggaagaacgg ggctttgtcg gtgctgcaga agagcatccg gccccaggtg
     1681 gtgacaacct ttgagcttcc cggctgctat gacatgtgga cagtcatcgc cccggtgcgt
     1741 aaggaggagg aggacaatcc caagggggag ggcacagagc aggaacccag caccacccct
     1801 gaagcagacg acgacggccg cagacacgga ttcctgattc tgagccggga agactccacc
     1861 atgatcctgc agacggggca ggagatcatg gagctggaca ccagtggctt cgccactcag
     1921 ggccccacgg tctttgctgg gaacatcggg gacaaccgct acattgtcca agtgtcacca
     1981 ctgggcatcc gcctgctgga aggagtgaat cagctgcact tcatccccgt ggacctgggc
     2041 gcccccatcg tgcagtgcgc cgtggccgac ccctatgtgg tcatcatgag tgccgagggc
     2101 cacgtcacca tgttcctgct gaagagtgac tcctacggtg gccgccacca ccgcctggcg
     2161 ctgcacaagc ccccgctgca ccatcagtcc aaggtgatta cgctgtgcct gtaccgagac
     2221 ctcagcggca tgttcaccac tgagagccgc ctgggtgggg cccgtgacga gctcgggggc
     2281 cgcagtggcc cggaggccga gggcctgggc tcagagacta gccccacagt ggatgacgag
     2341 gaggagatgc tgtatgggga ttcgggctcc ctcttcagcc ccagcaagga ggaggcccga
     2401 agaagcagcc agccccctgc tgaccgggac cctgcaccct tccgggcaga gcctacccac
     2461 tggtgcctgc tggtgcggga gaatggcacc atggagatct accagcttcc cgactggcgg
     2521 ctggtgttcc tggtgaagaa cttccctgtg gggcagcggg tccttgtgga cagctccttt
     2581 ggacagccca ctacacaggg cgaggcccgc agggaggagg ccacgcgcca gggggagctg
     2641 cccctcgtca aggaggtgct gctggtggcg ctgggcagcc gccagagcag gccctacctg
     2701 ctggtgcatg tggaccaaga gctgcttatc tacgaggcct tcccccacga ctctcagctc
     2761 ggccagggca atctcaaagt ccgctttaag aaggtccctc acaacatcaa cttccgtgag
     2821 aagaagccaa agccatccaa gaagaaagca gaaggtggcg gcgcagagga gggggctggg
     2881 gcccggggcc gcgtggcgcg tttccgctac ttcgaggata tttatggcta ctcaggggtc
     2941 ttcatctgcg gcccctcccc tcactggctc ttggtgaccg gccgaggggc tctgcggcta
     3001 caccccatgg ccatcgacgg cccggtcgac tctttcgctc cattccacaa tgtcaactgt
     3061 ccccgcggct tcctgtactt caacagacag ggcgagctga ggatcagtgt cctgcctgcc
     3121 tacctgtcct atgatgcccc atggcctgtc aggaagatcc cgctgcgctg cacggcccac
     3181 tatgtggctt accacgtgga gtctaaggtg tatgctgtgg ccaccagcac caacacgccg
     3241 tgtgcccgca tcccacgcat gactggcgag gagaaggagt ttgagaccat cgagagagat
     3301 gagcggtaca tccaccccca gcaggaggcc ttctccatcc agctcatctc cccggtcagc
     3361 tgggaggcta ttcccaatgc caggatcgag ctgcaggagt gggagcatgt gacctgcatg
     3421 aagacagtgt ctctgcgcag tgaggagacc gtgtcgggcc tcaaaggcta cgtggccgcc
     3481 gggacctgcc tcatgcaggg ggaggaggtc acgtgccgag ggcggatctt gatcatggat
     3541 gtgattgagg tggtgcccga gcctggccag cccttgacca agaacaagtt caaagtcctt
     3601 tacgagaagg agcagaaggg gcccgtgacc gccctgtgcc actgcaatgg ccacctggtg
     3661 tcggccatcg gccagaagat tttcctgtgg agcctgcggg ccagcgagct gacgggcatg
     3721 gccttcatcg acacgcagct ctacatacac cagatgatca gcgtcaagaa cttcatcctg
     3781 gcagccgacg tcatgaagag catttcgctg ctgcgctacc aggaggaaag caagacgctg
     3841 agcctggtgt cgcgggatgc caagcccctg gaggtgtaca gcgtggactt catggtggac
     3901 aatgcccagc tgggttttct ggtgtctgac cgcgaccgca acctcatggt gtacatgtac
     3961 ctgcccgaag ccaaggagag tttcgggggc atgcgcctgc tgcgtcgggc agacttccac
     4021 gtgggtgccc acgtgaacac gttctggagg accccgtgcc ggggggccac tgaagggctc
     4081 agcaaaaagt cggtcgtgtg ggagaataag cacatcacgt ggtttgccac cctggacggc
     4141 ggcatcgggc tgctgctgcc catgcaggag aagacctacc ggcggctgct gatgctgcag
     4201 aacgcgctga ccaccatgct gccacaccac gccggcctca acccccgcgc cttccggatg
     4261 ctgcacgtgg accgccgcac cctccagaat gccgtgcgca acgtgctgga tggggagctg
     4321 ctcaaccgct acctgtacct gagcaccatg gagcgcagcg agctagccaa gaagatcggc
     4381 accacaccag acataatcct ggacgacttg ctggagacgg accgcgtcac cgcccacttc
     4441 tagccccgtg gatgccgtca ccaccagcac acggaactac ctcccacccc ctttttgtac
     4501 aaaacacaag gaaaaacatt ttttgcttga
//
