LOCUS       XM_006716548            4471 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens cleavage and polyadenylation specific
            factor 1 (CPSF1), transcript variant X1, mRNA.
ACCESSION   XM_006716548
VERSION     XM_006716548.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000008.11) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_006716548.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4471
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="8"
     gene            1..4471
                     /gene="CPSF1"
                     /gene_synonym="CPSF160; HSU37012; MYP27; P/cl.18"
                     /note="cleavage and polyadenylation specific factor 1;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 155 ESTs, 578 long SRA reads, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 93 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:29894"
                     /db_xref="HGNC:HGNC:2324"
                     /db_xref="MIM:606027"
     CDS             62..4384
                     /gene="CPSF1"
                     /gene_synonym="CPSF160; HSU37012; MYP27; P/cl.18"
                     /codon_start=1
                     /product="cleavage and polyadenylation specificity factor
                     subunit 1 isoform X1"
                     /protein_id="XP_006716611.1"
                     /db_xref="GeneID:29894"
                     /db_xref="HGNC:HGNC:2324"
                     /db_xref="MIM:606027"
                     /translation="MYAVYKQAHPPTGLEFSMYCNFFNNSERNLVVAGTSQLYVYRLN
                     RDAEALTKNDRSTEGKAHREKLELAASFSFFGNVMSMASVQLAGAKRDALLLSFKDAK
                     LSVVEYDPGTHDLKTLSLHYFEEPELRDGFVQNVHTPRVRVDPDGRCAAMLVYGTRLV
                     VLPFRRESLAEEHEGLVGEGQRSSFLPSYIIDVRALDEKLLNIIDLQFLHGYYEPTLL
                     ILFEPNQTWPGRVAVRQDTCSIVAISLNITQKVHPVIWSLTSLPFDCTQALAVPKPIG
                     GVVVFAVNSLLYLNQSVPPYGVALNSLTTGTTAFPLRTQEGVRITLDCAQATFISYDK
                     MVISLKGGEIYVLTLITDGMRSVRAFHFDKAAASVLTTSMVTMEPGYLFLGSRLGNSL
                     LLKYTEKLQEPPASAVREAADKEEPPSKKKRVDATAGWSAAGKSVPQDEVDEIEVYGS
                     EAQSGTQLATYSFEVCDSILNIGPCANAAVGEPAFLSEEFQNSPEPDLEIVVCSGHGK
                     NGALSVLQKSIRPQVVTTFELPGCYDMWTVIAPVRKEEEDNPKGEGTEQEPSTTPEAD
                     DDGRRHGFLILSREDSTMILQTGQEIMELDTSGFATQGPTVFAGNIGDNRYIVQVSPL
                     GIRLLEGVNQLHFIPVDLGAPIVQCAVADPYVVIMSAEGHVTMFLLKSDSYGGRHHRL
                     ALHKPPLHHQSKVITLCLYRDLSGMFTTESRLGGARDELGGRSGPEAEGLGSETSPTV
                     DDEEEMLYGDSGSLFSPSKEEARRSSQPPADRDPAPFRAEPTHWCLLVRENGTMEIYQ
                     LPDWRLVFLVKNFPVGQRVLVDSSFGQPTTQGEARREEATRQGELPLVKEVLLVALGS
                     RQSRPYLLVHVDQELLIYEAFPHDSQLGQGNLKVRFKKVPHNINFREKKPKPSKKKAE
                     GGGAEEGAGARGRVARFRYFEDIYGYSGVFICGPSPHWLLVTGRGALRLHPMAIDGPV
                     DSFAPFHNVNCPRGFLYFNRQGELRISVLPAYLSYDAPWPVRKIPLRCTAHYVAYHVE
                     SKVYAVATSTNTPCARIPRMTGEEKEFETIERDERYIHPQQEAFSIQLISPVSWEAIP
                     NARIELQEWEHVTCMKTVSLRSEETVSGLKGYVAAGTCLMQGEEVTCRGRILIMDVIE
                     VVPEPGQPLTKNKFKVLYEKEQKGPVTALCHCNGHLVSAIGQKIFLWSLRASELTGMA
                     FIDTQLYIHQMISVKNFILAADVMKSISLLRYQEESKTLSLDAKPLEVYSVDFMVDNA
                     QLGFLVSDRDRNLMVYMYLPEAKESFGGMRLLRRADFHVGAHVNTFWRTPCRGATEGL
                     SKKSVVWENKHITWFATLDGGIGLLLPMQEKTYRRLLMLQNALTTMLPHHAGLNPRAF
                     RMLHVDRRTLQNAVRNVLDGELLNRYLYLSTMERSELAKKIGTTPDIILDDLLETDRV
                     TAHF"
ORIGIN      
        1 gagttcgctg ctgtcccggt tcctctcgag tcggctccaa ctgccagccc gggttggcgc
       61 catgtacgcc gtgtacaaac aggcgcatcc gcccaccggt ctggagttct ccatgtactg
      121 caacttcttc aacaacagcg agcgcaacct ggtagtggcc gggacctcgc agctctacgt
      181 gtaccgcctc aaccgcgacg ccgaggctct gaccaagaat gacaggagca cagaggggaa
      241 ggcccaccgg gagaagctcg agcttgctgc ctccttctcc ttctttggca acgtcatgtc
      301 catggccagc gtgcagctgg caggagccaa gcgggatgcc ctgctcctaa gcttcaagga
      361 tgccaagctg tctgtggtgg agtacgaccc gggcacccat gacctgaaga ccctgtcact
      421 gcactacttt gaggagcctg agcttcggga cgggtttgtg cagaatgtac acacgccgcg
      481 agtgcgggtg gaccccgacg ggcgctgtgc agccatgctt gtctacggca cgcggctggt
      541 ggtcctgccc ttccgcaggg agagcctggc tgaggagcac gaggggctcg tgggtgaggg
      601 gcagaggtcc agcttcctgc ccagctacat catcgacgtg cgggccctag acgagaagct
      661 gctcaacatc atcgacctgc agttcctgca tggctactac gagcctaccc tcctcatcct
      721 gtttgagccc aaccagacct ggcctgggcg cgtggccgtg cggcaggaca cgtgctccat
      781 tgtggccatc tcactgaaca tcacgcagaa ggtgcacccc gtcatctggt ccctcaccag
      841 cctgcccttt gactgcaccc aggctctggc tgtgcccaag cccataggtg gggtggtggt
      901 gtttgccgtc aactcgctgt tgtacctgaa ccagagcgtc cccccgtatg gcgtggctct
      961 caacagcctc accacaggaa ccacggcttt cccgcttcgc acccaggagg gtgtgcggat
     1021 caccctggac tgcgcccagg ccaccttcat ctcctacgac aagatggtca tctccctcaa
     1081 gggcggcgag atctacgtgc tgaccctcat caccgacggc atgcgcagtg tccgagcgtt
     1141 ccactttgac aaggcggccg ccagcgtcct caccaccagc atggtcacca tggagcccgg
     1201 gtacctgttc ctgggttctc gcctgggcaa ttccctcctc ctcaagtaca cggagaagct
     1261 gcaggagccc ccggccagtg ctgtccgtga ggctgccgac aaggaagagc ctccctcaaa
     1321 gaagaagcga gtggatgcga cggccggctg gtcagctgcg ggtaagtcgg tgccgcagga
     1381 tgaggtggac gagattgaag tgtacggcag cgaggcccag tcgggaacac agctggccac
     1441 ctactccttt gaggtgtgtg acagcatcct gaacattgga ccctgtgcca atgccgccgt
     1501 gggcgagcct gccttcctct ctgaagagtt tcagaacagc cccgagccgg acctggagat
     1561 tgtggtttgc tccggccacg ggaagaacgg ggctttgtcg gtgctgcaga agagcatccg
     1621 gccccaggtg gtgacaacct ttgagcttcc cggctgctat gacatgtgga cagtcatcgc
     1681 cccggtgcgt aaggaggagg aggacaatcc caagggggag ggcacagagc aggaacccag
     1741 caccacccct gaagcagacg acgacggccg cagacacgga ttcctgattc tgagccggga
     1801 agactccacc atgatcctgc agacggggca ggagatcatg gagctggaca ccagtggctt
     1861 cgccactcag ggccccacgg tctttgctgg gaacatcggg gacaaccgct acattgtcca
     1921 agtgtcacca ctgggcatcc gcctgctgga aggagtgaat cagctgcact tcatccccgt
     1981 ggacctgggc gcccccatcg tgcagtgcgc cgtggccgac ccctatgtgg tcatcatgag
     2041 tgccgagggc cacgtcacca tgttcctgct gaagagtgac tcctacggtg gccgccacca
     2101 ccgcctggcg ctgcacaagc ccccgctgca ccatcagtcc aaggtgatta cgctgtgcct
     2161 gtaccgagac ctcagcggca tgttcaccac tgagagccgc ctgggtgggg cccgtgacga
     2221 gctcgggggc cgcagtggcc cggaggccga gggcctgggc tcagagacta gccccacagt
     2281 ggatgacgag gaggagatgc tgtatgggga ttcgggctcc ctcttcagcc ccagcaagga
     2341 ggaggcccga agaagcagcc agccccctgc tgaccgggac cctgcaccct tccgggcaga
     2401 gcctacccac tggtgcctgc tggtgcggga gaatggcacc atggagatct accagcttcc
     2461 cgactggcgg ctggtgttcc tggtgaagaa cttccctgtg gggcagcggg tccttgtgga
     2521 cagctccttt ggacagccca ctacacaggg cgaggcccgc agggaggagg ccacgcgcca
     2581 gggggagctg cccctcgtca aggaggtgct gctggtggcg ctgggcagcc gccagagcag
     2641 gccctacctg ctggtgcatg tggaccaaga gctgcttatc tacgaggcct tcccccacga
     2701 ctctcagctc ggccagggca atctcaaagt ccgctttaag aaggtccctc acaacatcaa
     2761 cttccgtgag aagaagccaa agccatccaa gaagaaagca gaaggtggcg gcgcagagga
     2821 gggggctggg gcccggggcc gcgtggcgcg tttccgctac ttcgaggata tttatggcta
     2881 ctcaggggtc ttcatctgcg gcccctcccc tcactggctc ttggtgaccg gccgaggggc
     2941 tctgcggcta caccccatgg ccatcgacgg cccggtcgac tctttcgctc cattccacaa
     3001 tgtcaactgt ccccgcggct tcctgtactt caacagacag ggcgagctga ggatcagtgt
     3061 cctgcctgcc tacctgtcct atgatgcccc atggcctgtc aggaagatcc cgctgcgctg
     3121 cacggcccac tatgtggctt accacgtgga gtctaaggtg tatgctgtgg ccaccagcac
     3181 caacacgccg tgtgcccgca tcccacgcat gactggcgag gagaaggagt ttgagaccat
     3241 cgagagagat gagcggtaca tccaccccca gcaggaggcc ttctccatcc agctcatctc
     3301 cccggtcagc tgggaggcta ttcccaatgc caggatcgag ctgcaggagt gggagcatgt
     3361 gacctgcatg aagacagtgt ctctgcgcag tgaggagacc gtgtcgggcc tcaaaggcta
     3421 cgtggccgcc gggacctgcc tcatgcaggg ggaggaggtc acgtgccgag ggcggatctt
     3481 gatcatggat gtgattgagg tggtgcccga gcctggccag cccttgacca agaacaagtt
     3541 caaagtcctt tacgagaagg agcagaaggg gcccgtgacc gccctgtgcc actgcaatgg
     3601 ccacctggtg tcggccatcg gccagaagat tttcctgtgg agcctgcggg ccagcgagct
     3661 gacgggcatg gccttcatcg acacgcagct ctacatacac cagatgatca gcgtcaagaa
     3721 cttcatcctg gcagccgacg tcatgaagag catttcgctg ctgcgctacc aggaggaaag
     3781 caagacgctg agcctggatg ccaagcccct ggaggtgtac agcgtggact tcatggtgga
     3841 caatgcccag ctgggttttc tggtgtctga ccgcgaccgc aacctcatgg tgtacatgta
     3901 cctgcccgaa gccaaggaga gtttcggggg catgcgcctg ctgcgtcggg cagacttcca
     3961 cgtgggtgcc cacgtgaaca cgttctggag gaccccgtgc cggggggcca ctgaagggct
     4021 cagcaaaaag tcggtcgtgt gggagaataa gcacatcacg tggtttgcca ccctggacgg
     4081 cggcatcggg ctgctgctgc ccatgcagga gaagacctac cggcggctgc tgatgctgca
     4141 gaacgcgctg accaccatgc tgccacacca cgccggcctc aacccccgcg ccttccggat
     4201 gctgcacgtg gaccgccgca ccctccagaa tgccgtgcgc aacgtgctgg atggggagct
     4261 gctcaaccgc tacctgtacc tgagcaccat ggagcgcagc gagctagcca agaagatcgg
     4321 caccacacca gacataatcc tggacgactt gctggagacg gaccgcgtca ccgcccactt
     4381 ctagccccgt ggatgccgtc accaccagca cacggaacta cctcccaccc cctttttgta
     4441 caaaacacaa ggaaaaacat tttttgcttg a
//
