LOCUS       XM_047417541           11342 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens ciliogenesis and planar polarity effector
            complex subunit 1 (CPLANE1), transcript variant X5, mRNA.
ACCESSION   XM_047417541
VERSION     XM_047417541.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000005.10) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11342
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="5"
     gene            1..11342
                     /gene="CPLANE1"
                     /gene_synonym="C5orf42; Hug; JBTS17; OFD6"
                     /note="ciliogenesis and planar polarity effector complex
                     subunit 1; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 3 mRNAs, 44 ESTs, 442 long SRA
                     reads, 6 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 24 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:65250"
                     /db_xref="HGNC:HGNC:25801"
                     /db_xref="MIM:614571"
     CDS             223..9975
                     /gene="CPLANE1"
                     /gene_synonym="C5orf42; Hug; JBTS17; OFD6"
                     /codon_start=1
                     /product="ciliogenesis and planar polarity effector 1
                     isoform X2"
                     /protein_id="XP_047273497.1"
                     /db_xref="GeneID:65250"
                     /db_xref="HGNC:HGNC:25801"
                     /db_xref="MIM:614571"
                     /translation="MEIRLEILTSTGIKQKKPWPRVSWLGKEKEAVFLLDDKFINEIN
                     LLSGKIKKKIPSLQPFLKDVIVLTTSSNDAWLAGVLTTGELFLWNKDQDCLKTIPITE
                     KPKEMIKATVASSLRLYLYVSGNGKRIVLITPSGCIFLWEYLELKNILSSKSLSLAGR
                     WSQVIPEEAVLLPSTEDKEAVVNAVFIKNELFGDCCLCSFTFYSGECLKLTFLAIRWH
                     ENVFTSVRSLPYHVHWAQQDCHLCSLIPKCESVKSRGALISAFSRDGLTLAVTLNQKD
                     PKATQVLFINTLNFVTLCGSLKGCSNKSPVVPATLIRSYWVGDISWTHDSLFLACMLK
                     RGSLVLLTCQGELLTLITFGCSIEFGPAEFIPLHPLITYRPQQFTFQDSNNSVDSSAS
                     DSDPMRQRFSIKAHSRLPYLVISDGYMVTTLRFLDSLSPSVHMRSLLLDSTQRLEKIY
                     QSVILSKPKGKGLNLRSLNSLRSSLLEHQGNESSADFTVPKFLQAEETINENAADFQD
                     FEAEETNEGRHFPDNLCPFWNKRDDVLCSSMKEGRLEFASMFDTIHAKDDSEETDRTI
                     TELHSIQKSLLAAWTIGISKTVTEKNLMLNYIVVCITHFFYILQFIKCPFPKLDLVLS
                     KSSRHNAWILCIFQLFHQCLSIHYWDIRYKQDVGHLIKLTSNTVKLLLTQQQKGQLFS
                     EKLLACFYLLKMVADNLNGVYILQPEVISASADGSKITAQDSLVVPIFQMFQDSGFQK
                     NWSWNSFFKIHPQVVNPVQQPGHRLLILWRILYKKTLWYQAQLNRRVPEADSQLTEKM
                     THEASTVKSLLCHLQANLQSTGDCLNQTLELKSINGEECFLLGSYEKSVQLWKKALQE
                     IEEKGGRRTYFLQIRYYLSLLYCHLYSYNLNDAQGLCDQLAREILRWSQLPVKENKDF
                     SGAAKSHFECGMVGGVHPEAAVRVVQSMARFMAAYFTNQQLCILPPHHVNVLPPLHIK
                     TEQSFRLIPLQHSKVASVVRDQNLSNVWTVEYALELLFIGGLVPEAVWLAYKLGDWKT
                     SVSIGVAFQLFCKRDSNFMRSKKKSLNLPLRMTPAQIFQEKLQCVLGQPASLEAKNEM
                     GSKYKQFTDPIEEEDANLLFGSVQEVLKASVMADADILSETFQLLIDSAKDFSKRLWG
                     LVPFGLYLPAPPLYCPQPAILSEEDGDDLLLKAEKNNRQKVSGILQRVLLLFRAAQCS
                     FPVAQWYILQLRWARKVMQKIRMKGSLPSLSPFPQSLLNYCKGGIAFFRPGAAGDHKL
                     DEVSIRAIGCFRELCALCWMLHVRDKLSYSCRQYQKARENVKGEKDLEVEFDSCMIEH
                     CLSAVEWAYRMLPFSRFFNMEELIQDIILSLIGELPPIRKVAEIFVKAFPYPEDVRVP
                     LRDKYHSLHQRLRHCVVKGPQTEEMMSVVMHSIQKVRVKALKRVQRNIGSFEVNIWEP
                     IEEEKPDEAPGVDRYSLGTSLSRSTLTELGDSVVHSDADTFSEALSVEEKSRINIYQR
                     NAPNHMELTSIHKPTDKRKMCNQKENPTKKEDHEKLSQNTLPVIGVWEFERDDDEYIK
                     FLDLFLSYILERDLPYSRDADIPFLTSFSGKLREHELNSLLFDVHTTLKRHQSKTKSQ
                     NVFRAGSCFVVAPESYESEKSSSLNDEYGMHLENQKLSSSVLVNQGIKPFLQYPSNEV
                     NKNEGMSGLFGLKQRSIYKIQDDTREKCLIQRSSNHIFWTPKSIKTRRCIFKAIQCND
                     INPQEDLPLALNTFGSIGRLLEWMIRWSNRRLLCDSGITESSSEYSPVIRVKTSTAAI
                     LTSLWLLEQPYFATYKAKNAIIKMVENRDTGCQIGPNIERESKSDAGGSVAVATPGGT
                     EERNGQNKSCQNILKMPTEAKNPDIKEINDDIISITHNTKKEFIDIDENLLEVEAFTE
                     EEMDMHISDYEEDIEESVGGFRSPSLAICMMTLPQQLEEEFTEEVQCQREEPLETIME
                     EKSTEQKGMIEAFSHPGHTTPQSMQVDTSSEISSAQISTYKEKSSSVPLLISNGVNVA
                     SQPPAPTPQKTQRNEFTAQLPDCSESVRQMLQDEMFKLVQLQQINFMSLMQIVGSSFA
                     NLPDTQQLVQQSQSVHLGESQESNLRGCGDVEDSNKNLKERFFIKPQSMGENAREPRK
                     NSPHCHEGTIPSGQNSTGNVQNVPHGSIPLCQLNGQPRKKGPIPSSQNLPSTSFYPAP
                     AGNTHLYLLSTPSVVQKAPRLIPHAKTFSPGDGFPLLQFKSKQEFQPLFLHTGSIPQV
                     PFRPLPQPREAWGLSDSFQPALPQRAAQTTPASHLNVSQYNTEARKKEVEQKTWAETV
                     ITEIPNHVNLDQYVGQENLTPQQDSSVFIKPEKLFDVKPGTLEISPHHSFGLPLLYLP
                     LKPPNMFPSTSRASITVPSTPIQPIAEERKYPRLSLLHSHLSPENRCKKTQLIPLENL
                     IAFKQSQQKLTHNLFEQGDAGHLQLLKVKIEPPEVRQGKDSKKRQRRRAEKELQEKRC
                     EKLRRKPNVTFRPENSIINNDDSEIIKKPKEQQEHCGSHPLDDFDVPFEMLQDDNTSA
                     GLHFMASVKKKAIGSQDASTNTDPEHEPLTAPQLLVPDVYLNLKLSSEMSEKPWSPSI
                     PHTVTNLVGHTYINVIDIEANDLLQELPVREEPSNDNVIKQQSDHLAVPSSAELHYMA
                     ASVTNAVPPHNFKSQEVTPACLDGKSLRAGITEVKEPSVTSPTPSDIQQNKGLPKPEF
                     RFKGQSTKSDSAEDYLLWKRLQGVSAACPAPSSAAHQLEHLSAKLQKIDEQLLAIQNI
                     AENIEQDFPKPEMLDLHCDKIGPVDHIEFSSGPEFKKTLASKTISISEEVRFLTHMDE
                     EDQSDKKETSEPEFSITENYSGQKTCVFPTADSAVSLSSSSDQNTTSPGMNSSDELCE
                     SVSVHPLQMTGLTDIADIIDDLIIKDGVSSEELGLTEQAMGTSRIQHYSGRHSQRTDK
                     ERREIQAWMKRKRKERMAKYLNELAEKRGQEHDPFCPRSNPLYMTSREIRLRQKMKHE
                     KDRLLLSEHYSRRISQAYGLMNELLSESVQLPTLPQKPLPNKPSPTQSSSCQHCPSPR
                     GENQHGHSFLINRPGKVKYMSKPSYIHKRKSFGQPQGSPWPHGTATFTIQKKAGGAKA
                     AVRKATQSPVTFQKGSNAPCHSLQHTKKHGSAGLAPQTKQVCVEYEREETVVSPWTIP
                     SEIHKILHESHNSLLQDLSPTEEEEPEHPFGVGGVDSVSESTGSILSKLDWNAIEDMV
                     ASVEDQGLSVHWALDL"
     polyA_site      11342
                     /gene="CPLANE1"
                     /gene_synonym="C5orf42; Hug; JBTS17; OFD6"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 gtcgccagga cgcaggctcg cgtcagggct ggcggtaggg cccgcagctg tcggcctggc
       61 gtcttcaccc cgcgcagtcg gcctcgccta gccttctcgc gcctgactgg ccggaccctg
      121 cccctggcgg aggtaactgc ccgcggattc cttaccccgc gatcctggcc tcctcaatct
      181 tgggactgtt ttacttaatt ggtcattgat agcttaacaa acatggagat aagattagaa
      241 atcttgacat caacaggtat taagcagaaa aaaccatggc cacgtgtctc ctggttggga
      301 aaggaaaaag aagccgtttt tcttttggat gataaattca taaatgaaat taatttgcta
      361 tcaggaaaga taaagaagaa aattcctagt ctgcagcctt tcttgaagga tgttattgtc
      421 ctaacaacat ccagtaatga tgcctggctg gctggggtac taactacagg agagcttttc
      481 ctttggaaca aagatcaaga ttgtttgaaa actataccaa taactgaaaa gcctaaggaa
      541 atgatcaaag ctacagtcgc aagctctttg agactgtact tgtatgtatc tggaaatggg
      601 aaaagaattg tgctcataac accttctgga tgcatatttc tttgggaata tttggaatta
      661 aagaatatct tatcttctaa aagcctttca ttggcgggtc ggtggtccca ggtcatacct
      721 gaagaagcag ttctcttgcc ttccaccgaa gataaagaag ctgtagtgaa tgctgttttt
      781 ataaaaaatg agttatttgg agactgctgc ctgtgttcat ttacttttta ttctggggaa
      841 tgcctgaagt taacatttct agcaattcgg tggcatgaga atgtatttac atctgtaaga
      901 tcattgccat accatgttca ttgggctcaa caagactgtc atctctgtag tttaattcct
      961 aaatgtgaat cagtaaagtc aagaggagct ctaatttctg ccttttcaag agatggcctt
     1021 accctggcag taactcttaa tcagaaagac cccaaggcaa ctcaggtatt atttataaac
     1081 acactgaatt ttgttactct ctgtggtagc cttaaaggat gtagtaacaa gagtcccgtg
     1141 gttccagcta cacttattag gtcctactgg gtaggtgata tcagctggac gcatgatagt
     1201 ctttttctgg cttgtatgtt aaaacgtggc tctctggttt tattgacctg ccaaggtgaa
     1261 ttgctaacat taattacatt tggttgctct atagaatttg gcccagcaga atttattcct
     1321 cttcatccac taataacgta tagaccacag cagtttacgt ttcaagattc aaataattct
     1381 gttgattcat cagcttctga tagtgaccct atgagacaga gattttctat aaaagcacac
     1441 tcacggttac cctacctcgt tatatctgat ggatatatgg tcacaaccct tcgatttctt
     1501 gatagcctat ctccatcagt acacatgaga tcacttctac ttgattcaac ccagaggctt
     1561 gagaaaatat atcaaagtgt gatattgtct aagccaaaag gcaaaggact gaacttgcga
     1621 tcactgaatt ccctaaggtc tagcctgtta gaacaccaag gaaatgaaag ttcagccgat
     1681 ttcactgtcc ccaaattctt gcaggcagaa gaaacaataa atgaaaatgc agcagatttt
     1741 caggattttg aagcagaaga aactaacgaa ggcagacact ttccagacaa cttatgtcct
     1801 ttttggaaca aaagagatga tgtgctgtgt agtagtatga aggaaggaag attggaattt
     1861 gcatctatgt ttgatacgat acatgcaaag gatgatagtg aggagacaga tagaaccatt
     1921 acagaactgc attctatcca gaaaagtcta cttgcagcgt ggactatagg aatttcaaaa
     1981 actgtgacag aaaaaaattt aatgttaaat tacatagtag tttgtatcac tcattttttt
     2041 tacattcttc aatttataaa atgtcctttt cctaaacttg atcttgtttt aagcaaaagc
     2101 tcaagacata atgcatggat actttgtatc tttcaacttt ttcatcagtg tttatcaatc
     2161 cattattggg atataagata caaacaagat gtggggcatt tgataaagct gacctcaaat
     2221 actgtaaaac ttttgctgac tcagcaacaa aagggtcagt tattctcaga gaaactttta
     2281 gcttgttttt atttactcaa aatggtagct gacaatttaa atggtgtata cattcttcaa
     2341 cctgaagtta tttcagcatc agctgatgga agtaaaataa cagctcaaga ctcattggtg
     2401 gtacctattt ttcagatgtt tcaagatagt ggttttcaga aaaactggtc ttggaactca
     2461 tttttcaaga ttcatcctca agtagtaaat cctgtgcaac agccaggaca cagattgctt
     2521 attctctgga gaatactgta caaaaaaact ttatggtatc aagcacaatt aaatcgaaga
     2581 gttcctgaag ctgatagtca gttaactgaa aagatgacac atgaagcatc tactgtcaag
     2641 tccctgttat gtcatttgca ggctaaccta cagagtactg gagattgctt gaatcaaacc
     2701 ttagaactta aatctatcaa tggggaagaa tgttttttat taggatcata tgaaaagtct
     2761 gttcagctgt ggaaaaaagc tctacaagaa atcgaagaga aaggaggaag aaggacgtat
     2821 tttcttcaga tacgctatta tctttctctc ttatactgcc acctctatag ctataattta
     2881 aatgatgctc aaggattgtg tgatcagcta gcaagagaaa tcctgagatg gtcccaacta
     2941 cctgtaaaag aaaataaaga tttttcaggt gctgcaaagt ctcattttga gtgtggaatg
     3001 gtgggcggtg ttcatcctga ggcagcagtg agagtcgtcc agtccatggc tcgtttcatg
     3061 gctgcctatt tcaccaatca gcagctttgc attttgcccc ctcatcatgt gaatgttctt
     3121 cccccacttc atattaaaac agagcagtcc tttcgactta ttcctctgca acactctaag
     3181 gtggccagtg ttgttagaga tcagaatctc tctaatgtgt ggacagttga atatgcactt
     3241 gaattactat ttattggtgg cctggttcca gaggctgtgt ggttggcata taaacttgga
     3301 gactggaaga cgtctgtttc aattggtgtg gctttccagc tgttctgtaa acgtgatagc
     3361 aatttcatga ggtccaagaa aaagagtctg aatctaccac tccgtatgac tccagcacag
     3421 atttttcagg aaaaactgca gtgtgtttta ggtcaaccag cctctttgga agcaaaaaat
     3481 gaaatgggct caaaatataa acagtttaca gatcccattg aagaggaaga tgcaaatctg
     3541 ctatttggtt cagtacaaga agtactgaaa gcatcagtta tggccgatgc agatattctt
     3601 tcggagacat ttcaacttct gatagactct gccaaggact tcagtaaaag actgtggggc
     3661 ttagtgccat tcggcttgta tcttccagct cctccattgt actgtcccca gccagctatt
     3721 cttagtgaag aagatggtga tgatcttctt ttaaaagctg aaaaaaataa tcgccagaag
     3781 gtatctggaa tccttcagcg tgttctcctg cttttccggg cggctcagtg ttcttttcct
     3841 gtagcacagt ggtatatatt gcagttgagg tgggcaagaa aagtcatgca gaagattcga
     3901 atgaaaggat cccttccttc actgagtcct tttcctcagt cattacttaa ttactgtaaa
     3961 ggaggtatcg cattttttag acctggagca gctggagacc acaagcttga tgaagtttcc
     4021 attagagcaa taggttgctt cagagaactt tgtgctctgt gttggatgct gcatgtccgt
     4081 gataagttat cctatagttg caggcaatat cagaaagcaa gagaaaatgt aaaaggagaa
     4141 aaggaccttg aagtggagtt tgattcttgt atgattgagc actgtcttag tgcagtggaa
     4201 tgggcttata gaatgctgcc tttctctcgg ttttttaata tggaagaact tattcaggat
     4261 ataattttga gccttattgg agaactgcca ccaatcagaa aggtagcaga aattttcgtg
     4321 aaagcatttc cctatcctga ggacgtgagg gttcctttaa gagacaaata tcactctctt
     4381 caccagagac tcagacactg tgttgtgaaa ggaccccaga ctgaggaaat gatgtctgtt
     4441 gtcatgcatt ctatccagaa agtgagggtg aaagctctaa aacgtgtgca gagaaatata
     4501 ggctcttttg aagtgaatat atgggaacca attgaagaag agaaaccaga tgaggctcca
     4561 ggtgttgaca gatattccct ggggactagt ttgagcagaa gtacactcac agaactagga
     4621 gattctgtgg ttcacagtga tgcagatacg ttctctgaag ctttgtcggt tgaagaaaaa
     4681 agtaggataa atatctatca aagaaatgcc ccaaatcaca tggaattaac atcaattcat
     4741 aagccaactg ataaaaggaa aatgtgtaat cagaaagaaa atcctacaaa gaaagaagat
     4801 catgaaaagt tatcacaaaa tacacttcct gtaataggtg tttgggaatt tgaacgtgat
     4861 gatgatgaat atattaaatt ccttgatctg tttttgagtt acattcttga aagagaccta
     4921 ccttattcca gggatgctga cattccattt ctaactagtt tttctggaaa gcttagagaa
     4981 catgaactta attctttact ttttgatgta catacaacat taaaacgaca tcagagcaaa
     5041 actaaaagcc agaatgtgtt tagagctggt tcttgctttg ttgttgctcc tgagtcctat
     5101 gaatcagaaa aatcatcctc tttaaatgat gaatatggca tgcatttaga aaaccagaaa
     5161 ctttcatcat cagtactggt taatcaaggg atcaaacctt ttttacaata tccttcgaat
     5221 gaagtcaata agaatgaagg aatgagtgga ttatttggtt taaaacaaag gtcaatttac
     5281 aaaatacaag atgacactag agagaaatgt ctaatccaga gatcatcaaa ccacattttt
     5341 tggactccca agtccattaa aactagaaga tgtattttca aagctattca gtgcaatgat
     5401 attaaccctc aagaagatct tcctttagca ctaaacactt ttggcagtat aggaagactg
     5461 ctggaatgga tgataaggtg gtctaataga aggctactct gtgattctgg tataactgag
     5521 tcatcctctg agtacagtcc agtaattcgt gtaaagacct ctacagctgc cattcttaca
     5581 tcattatggc ttttggaaca accctatttt gctacatata aggcaaaaaa tgccattatt
     5641 aagatggtag agaatcgtga cactgggtgt cagattggac ccaatattga gagggagagc
     5701 aaatcagatg ctggcggttc agttgcagta gcaactccag gtggaactga ggaaagaaat
     5761 ggtcagaata aatcttgtca aaatatcttg aaaatgccaa ctgaagcaaa aaatcctgat
     5821 ataaaagaaa tcaatgatga tattatttcc atcactcata atactaaaaa agaatttata
     5881 gatattgatg agaatctttt agaagtagaa gcatttacag aagaggaaat ggatatgcac
     5941 atatcagact atgaagaaga cattgaagaa tctgttggag gtttcagaag tcccagtctt
     6001 gccatttgca tgatgacttt accacagcag ttagaagaag agttcacaga agaggttcag
     6061 tgtcaaaggg aagaaccact ggagacaatt atggaggaaa aatcgactga acaaaaaggt
     6121 atgatcgaag ccttttcaca tcctgggcat accactcctc aatcaatgca agtagatacg
     6181 agttcagaaa tttctagtgc acagatttct acatataaag aaaaatcttc ctcagttcca
     6241 cttctgatat caaatggagt caatgttgct tcacaaccac ctgctccaac acctcagaag
     6301 acccagagaa atgaattcac ggctcagtta ccagattgtt cggagtccgt taggcagatg
     6361 ctgcaagatg aaatgtttaa attagttcag ctgcaacaga tcaacttcat gagcctaatg
     6421 caaatagtag gatcatcctt tgctaatctc ccagatacac aacaacttgt acagcagtct
     6481 cagtctgtgc atttagggga aagccaagaa tcaaacctaa gaggatgtgg tgatgttgaa
     6541 gacagcaaca aaaatcttaa ggagagattt tttattaaac cacagtcaat gggagagaac
     6601 gccagagagc ctcgcaagaa cagcccacac tgccatgaag gaactatccc atctggtcaa
     6661 aatagtactg gaaacgtaca gaatgttcca catgggagta ttcctttatg tcaattaaat
     6721 ggccagcccc ggaaaaaagg accaattcca tcatctcaaa acttaccatc cacttcgttt
     6781 tatccagctc ctgctggaaa tactcacctc taccttttgt ccacaccttc tgttgttcag
     6841 aaggcaccta gacttatccc acatgcaaaa acatttagtc ctggtgatgg ctttcctttg
     6901 cttcaattta agtctaaaca agaattccag ccccttttct tacatacagg aagtattcca
     6961 caagttccct tcaggccttt gccacaacca agagaggctt ggggattatc tgactccttc
     7021 caacctgctc tgccacagag agcagcacaa actactccag catcccattt gaatgtaagc
     7081 cagtataaca ctgaagccag aaaaaaagaa gttgagcaga agacgtgggc agaaactgta
     7141 attacagaaa ttcctaatca tgtgaacttg gatcaatatg ttggacaaga aaatttgaca
     7201 cctcaacagg actcttcagt gtttataaaa ccagaaaaac tatttgatgt taagccaggg
     7261 acccttgaga tatctcctca ccattccttt ggacttccgt tactatacct gccacttaaa
     7321 cctcctaata tgtttccatc aacctcaaga gcatctatta cagttccctc aacacctatc
     7381 caacctatag cagaagaaag aaaataccca agattgtcat tacttcattc acatttgtcc
     7441 ccagaaaata ggtgcaaaaa aacacaactt atcccacttg aaaacctcat tgcgtttaaa
     7501 caaagccaac agaaactaac acataattta tttgaacaag gtgatgctgg acaccttcaa
     7561 cttctaaagg tcaaaataga accacctgaa gtaagacaag gaaaggacag taaaaaaagg
     7621 caaagaagaa gagctgagaa agagctgcaa gaaaaaagat gtgagaaact gaggagaaaa
     7681 ccaaatgtga cttttcgacc agagaattcc ataattaata atgatgattc agaaatcatt
     7741 aagaaaccca aggaacaaca agaacattgt ggttcccatc ctttggatga cttcgacgtt
     7801 ccttttgaaa tgctacaaga tgataatact tcagctggat tgcatttcat ggcctctgta
     7861 aaaaagaaag ctataggaag tcaagatgca agtacaaata cagacccaga acatgagcct
     7921 ttgactgctc ctcagctctt ggtcccagat gtctatctaa atctgaagct ttccagtgaa
     7981 atgtcagaga aaccttggtc accctcaata cctcatacag taacaaactt ggttggacat
     8041 acttatataa atgtgattga cattgaagct aatgatcttc tacaggaatt acctgtgaga
     8101 gaagagcctt caaatgataa tgttatcaaa cagcaaagcg atcatctagc agttccatcg
     8161 tctgcagagt tacattatat ggcagcttca gttactaatg ctgttccccc acataatttt
     8221 aagagtcaag aagtaactcc agcttgtctg gatggaaaaa gcttgagagc aggcattaca
     8281 gaagtgaagg agcctagtgt cacctcacct acaccatcag acatacagca gaacaaaggt
     8341 ctgccaaaac cagagttccg attcaaagga cagagcacaa agtcagactc tgcagaagat
     8401 tatctattgt ggaaacggct gcaaggtgtc tctgcagctt gccctgcacc aagctctgca
     8461 gctcaccaac tagagcatct cagtgctaag cttcagaaaa ttgacgagca gttgctagca
     8521 atacagaaca ttgctgaaaa catagaacag gatttcccca agcctgaaat gctagatcta
     8581 cattgtgata agattggacc agtggatcac attgaattct cttctggccc tgaattcaaa
     8641 aaaacattag cttcaaaaac cattagcatt tctgaagaag tgcgtttttt gacccatatg
     8701 gatgaagaag atcaaagtga caaaaaggag acttcagaac ctgaattttc aataacagaa
     8761 aattattctg gtcagaaaac ctgtgtgttt cctactgccg attcagctgt cagcctttcc
     8821 agttccagtg atcagaatac tacttctcct ggtatgaata gcagtgatga attgtgtgag
     8881 agtgtttcag tacatccgct ccagatgact ggattgactg atattgcaga cattattgat
     8941 gaccttataa ttaaagacgg agtttccagt gaagaacttg gcttaacaga acaagctatg
     9001 ggcacctcca gaattcagca ttattctggc agacattcac aaagaactga caaggaaaga
     9061 agagagattc aagcctggat gaaaagaaaa cgaaaagaaa gaatggcaaa gtacttaaat
     9121 gagctggcag aaaagagagg gcaagaacat gatcctttct gtcccagaag caatccactt
     9181 tacatgactt caagggaaat aaggctgaga caaaagatga agcatgaaaa agacagattg
     9241 ctgctctctg aacactatag tcgtcgaatc tcacaagcgt acggtctgat gaatgaactg
     9301 ttatctgagt cagtacagct accaactcta ccacagaaac cattgcctaa caaacccagc
     9361 cctactcagt cttccagttg tcaacactgc ccttctccaa gaggagagaa tcaacatggt
     9421 cacagttttc taataaatcg acctggaaaa gtcaaatata tgtccaaacc gagttatatc
     9481 cataagagga agtcttttgg gcaacctcaa ggctcacctt ggccacatgg aactgccact
     9541 ttcaccatac agaaaaaagc tggtggagcc aaagcagcag taagaaaggc tacgcagtct
     9601 ccagttacct tccaaaaagg ctctaatgct ccgtgtcata gtctgcagca tacaaaaaaa
     9661 catggaagtg ctgggcttgc acctcaaacc aagcaggtgt gtgtagagta tgaaagagag
     9721 gagactgtgg tgagtccctg gacgatacct tcagaaatcc ataagattct tcatgagagt
     9781 cacaattccc ttctacaaga cttgtctcca actgaagagg aagagccaga gcatcctttt
     9841 ggggtgggcg gtgtggacag cgtgtctgag agcactggca gcatcctcag caagctggac
     9901 tggaatgcca tcgaagacat ggtggccagc gtggaggacc agggcctgtc tgtccactgg
     9961 gccctggacc tgtaagacct ggatatcatt gggtttccat gcacaggcca gcacctcagt
    10021 aatgtggttc tgaaagatta acaggtttaa gggacagaag caatgaaaga agcaatgtga
    10081 attttccatt tgctttcata ttattacctg gattagccat taccagagga aaaataaaca
    10141 tttctcagta actttgcctt tatggggaaa gggttgacta ttgatgtatt atatgttttt
    10201 gtatttgatg catcattagg cataattttt aaaatgataa gtacctttca agccaagttt
    10261 gcataaccta ctttcaataa aaaccctcta tcttgcctcc tcctttatta ccctctgagt
    10321 tttgagaaac aaccatatac agatgaatct aataggaaaa aaaaaaatct tttcattgag
    10381 aagaaaatca gtctcacctg agaactcaat tatgaaccct attttaaaac acctatgcag
    10441 ggtttagcct aggagtgaaa agaaaaacca actacctttt accaaccctg aatctctaaa
    10501 taagcaaagt ttcatggagg ccaggagatc ttctgtcttc tgccctgtag cctgaagcct
    10561 tggaggaaga aacaggaatg gatgctttgg gcaggaaagt aagggaatat gactccggcc
    10621 tctagaaggc tcatcttaaa tttgtaagaa ccatggtaca gagacctgat tagtttttgg
    10681 tattgtgctc caataatgtc atagttttaa gagataattt ttatgagaat tgactaagaa
    10741 ccagtatcct tcaactactt catcaatgtt tggtataata taaaagcaca ctatcatctg
    10801 aaaaagctat taaatacccc tctttttcca aatatctacc tgtgtgaagc caggttttac
    10861 aacatgtatt gcagcaagtt gaatgcagaa gcaggtatgg taattcagct gccttctatc
    10921 aagctaaaca ttaaagagat ttgtagaact ataaaacaat gctactctcc ttaccaaatt
    10981 gttttagaaa atagctttat aggctaacat tattgttaat tgtcatttaa ttgttttgtc
    11041 atttaaaata ttttaaattg ttttctgtta gtttcttttt tgtatattct atgggtattt
    11101 tattgataca tgatagttgt acatttttat ggggtgcatg tgatattttg atatgtgcat
    11161 acaatgtgta gcaatcaaat cagggtaatt gggatattca tcacctcaaa catttatcat
    11221 ttatttgtgt tggaaacatt caaacctttt cttctagcta tttatccatt gttggatact
    11281 tatatcaatt ctatatctta gctgttgtga atagagctgc aataaatgta ggagtgcaga
    11341 ta
//
