LOCUS       XM_011527917            5947 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens C3 and PZP like alpha-2-macroglobulin
            domain containing 8 (CPAMD8), transcript variant X1, mRNA.
ACCESSION   XM_011527917
VERSION     XM_011527917.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000019.10) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011527917.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5947
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
     gene            1..5947
                     /gene="CPAMD8"
                     /gene_synonym="ASGD8; K-CAP; VIP"
                     /note="C3 and PZP like alpha-2-macroglobulin domain
                     containing 8; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 28 ESTs, 19 long SRA reads, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 4 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:27151"
                     /db_xref="HGNC:HGNC:23228"
                     /db_xref="MIM:608841"
     CDS             28..5790
                     /gene="CPAMD8"
                     /gene_synonym="ASGD8; K-CAP; VIP"
                     /codon_start=1
                     /product="C3 and PZP-like alpha-2-macroglobulin
                     domain-containing protein 8 isoform X1"
                     /protein_id="XP_011526219.1"
                     /db_xref="GeneID:27151"
                     /db_xref="HGNC:HGNC:23228"
                     /db_xref="MIM:608841"
                     /translation="MAPGALRGGCEQRAPGGGARTAALGPWPWPSPGPAPSPGAAPPR
                     SRKMSGALLWPLLPLLLLLLSARDGVRAAQPQAPGYLIAAPSVFRAGVEEVISVTIFN
                     SPREVTVQAQLVAQDKGTIKLKVPTGLRGQALLKVWGRGWQAEEGPLFHNQTSVTVDG
                     RGASVFIQTDKPVYRPQHRVLISIFTVSPNLRPVNEKLEAYILDPRGSRMIEWRHLKP
                     FCCGITNMSFPLSDQPVLGEWFIFVEMQGHAYNKSFEVQKYVLPKFELLIDPPRYIQD
                     LDACETGTVRARYTFGKPVAGALMINMTVNGVGYYSHEVGRPVLRTTKILGSRDFDIC
                     VRDMIPADVPEHFRGRVSIWAMVTSVDGSQQVAFDDSTPVQRQLVDIRYSKDTRKQFK
                     PGLAYVGKVELSYPDGSPAEGVTVQIKAELTPKDNIYTSEVVSQRGLVGFEIPSIPTS
                     AQHVWLETKVMALNGKPVGAQYLPSYLSLGSWYSPSQCYLQLQPPSHPLQVGEEAYFS
                     VKSTCPCNFTLYYEVAARGNIVLSGQQPAHTTQQRSKRAAPALEKPIRLTHLSETEPP
                     PAPEAEVDVCVTSLHLAVTPSMVPLGRLLVFYVRENGEGVADSLQFAVETFFENQVSV
                     TYSANETQPGEVVDLRIRAARGSCVCVAAVDKSVYLLRSGFRLTPAQVFQELEDYDVS
                     DSFGVSREDGPFWWAGLTAQRRRRSSVFPWPWGITKDSGFAFTETGLVVMTDRVSLNH
                     RQDGGLYTDEAVPAFQPHTGSLVAVAPSRHPPRTEKRKRTFFPETWIWHCLNISDPSG
                     EGTLSVKVPDSITSWVGEAVALSTSQGLGIAEPSLLKTFKPFFVDFMLPALIIRGEQV
                     KIPLSVYNYMGTCAEVYMKLSVPKGIQFVGHPGKRHVTKKMCVAPGEAEPIWVVLSFS
                     DLGLNNITAKALAYGDTNCCRDGRSSKHPEENHADRRVPIGVDHVRRSVMVEAEGVPR
                     AYTYSAFFCPSERVHISTPNKYEFQYVQRPLRLTRFDVAVRAHNDARVALSSGPQDTA
                     GMIEIVLGGHQNTRSWISTSKMGEPVASAHTAKILSWDEFRTFWISWRGGLIQVGHGP
                     EPSNESVIVAWTLPRPPEVQFIGFSTGWGSMGEFRIWRKMEVDESYSEAFTLGVPHGA
                     IPGSERATASIIGDVMGPTLNHLNNLLRLPFGCGEQNMIHFAPNVFVLKYLQKTQQLS
                     PEVERETTDYLVQGYQRQLTYKRQDGSYSAFGERDASGSMWLTAFVLKSFAQARSFIF
                     VDPRELAAAKSWIIQQQQADGSFLAVGRVLNKDIQGGIHGTVPLTAYVVVALLETGTA
                     SEEERGSTDKARHFLESAAPLAMDPYSCALTTYALTLLRSPAAPEALRKLRSLAIMRD
                     GVTHWSLSNSWDVDKGTFLSFSDRVSQSVVSAEVEMTAYALLTYTLLGDVAAALPVVK
                     WLSQQRNALGGFSSTQDTCVALQALAEYAILSYAGGINLTVSLASTNLDYQETFELHR
                     TNQKVLQTAAIPSLPTGLFVSAKGDGCCLMQIDVTYNVPDPVAKPAFQLLVSLQEPEA
                     QGRPPPMPASAAEGSRGDWPPADDDDPAADQHHQEYKVMLEVCTRWLHAGSSNMAVLE
                     VPLLSGFRADIESLEQLLLDKHMGMKRYEVAGRRVLFYFDEIPSRCLTCVRFRALREC
                     VVGRTSALPVSVYDYYEPAFEATRFYNVSTHSPLARELCAGPACNEVERAPARGPGWF
                     PGESGPAVAPEEGAAIARCGCDHDCGAQGNPVCGSDGVVYASACRLREAACRQAAPLE
                     PAPPSCCALEQRLPASSSSTYGDDLASVAPGPLQQDVKLNGAGLEVEDSDPEPEGEAE
                     DRVTAGPRPPVSSGNLESSTQSASPFHRWGQTPAPQRHSGRVVGAHRPGLLSPVFVYS
                     PAFQSGGEEGLWMSNTCTLR"
ORIGIN      
        1 agcttggccg ggcgcggagc ggggcgcatg gcgccgggcg cactgcgcgg gggctgcgaa
       61 caaagggccc ccggcggcgg cgcgaggacg gccgcgctcg gaccctggcc ctggcccagc
      121 cctggcccgg ccccctcccc aggcgcggcg ccccccagga gccgaaaaat gagcggcgcc
      181 ctgctctggc cgttgctccc gctcctgctc ctgctgctgt cggcgcggga cggcgtgcgc
      241 gccgcgcagc ctcaggcccc gggttacttg attgcagctc cctctgtttt tcgcgcgggc
      301 gtggaggaag tcatcagcgt gaccatcttt aactctccaa gggaagtcac ggtccaggct
      361 cagctggtgg cccaggataa agggacaatc aaactcaagg tgcccacggg cctccggggc
      421 caagcgcttc tgaaagtgtg gggccgcggc tggcaggcgg aggaggggcc cctctttcac
      481 aaccagacct cggtgaccgt ggacggccgg ggcgcttctg tattcatcca gacggacaag
      541 cctgtgtaca gaccccagca ccgagtgctc ataagcatct tcaccgtctc tccaaatctg
      601 aggcctgtca acgagaagct ggaagcctac atcctggacc cccgaggctc tcggatgata
      661 gagtggagac acttaaagcc gttctgctgc ggcatcacca acatgagctt ccccttgtcc
      721 gaccagcctg tgttgggaga atggttcatt tttgttgaaa tgcaaggcca cgcgtacaac
      781 aagtcttttg aagttcagaa gtatgtgttg cccaagtttg agcttctgat tgacccgccc
      841 cggtatatcc aagacctgga cgcctgtgag acaggcactg tgcgggccag gtataccttt
      901 gggaaacctg tggctggtgc cttaatgatc aacatgactg ttaatggtgt agggtactac
      961 agccacgagg tgggacgccc tgtcctcaga acaaccaaga tcctcggctc ccgggacttc
     1021 gacatctgcg tgagggacat gatcccagcg gacgtccctg agcacttccg gggcagggtc
     1081 agcatctggg ccatggtgac cagtgtggac gggagccagc aggtcgcgtt cgatgactcc
     1141 acccccgtgc agaggcagct ggtggacatc cggtactcca aggacacgag gaagcagttc
     1201 aagccgggcc tggcctacgt ggggaaggtg gagctatcct accccgatgg cagcccagct
     1261 gagggggtga cggtccagat taaggcagag ctgacaccaa aggataacat ctacaccagt
     1321 gaagttgtgt cccagcgtgg actagtgggg tttgaaatcc cctccatccc cacgtcagcc
     1381 cagcacgtgt ggctggagac caaggtgatg gcactgaacg ggaagcctgt gggggctcag
     1441 tacctgccca gctacctctc cctcggcagc tggtactccc ccagccagtg ctacctgcag
     1501 ctgcagccac cctcccaccc actgcaggtt ggggaagaag cctatttttc tgtgaagtcc
     1561 acatgtccct gcaactttac cctgtactac gaggtggctg cacggggcaa tattgtgcta
     1621 tcgggccagc agcctgccca caccacccag cagcgaagca agcgggcggc ccctgccctg
     1681 gagaaaccga ttcgtttaac acacctttct gagacagagc ccccaccagc cccagaagct
     1741 gaggtcgacg tgtgtgtgac ctctcttcat ctggccgtga cccccagcat ggtccccctt
     1801 ggtcgcctgc tggtcttcta cgtcagggag aatggagaag gggtcgccga cagccttcag
     1861 tttgcagtcg agaccttctt cgaaaaccag gtttcagtga cgtattcagc aaatgagacc
     1921 caacctgggg aggttgtcga cctgcggatc agggctgcaa ggggcagctg tgtgtgcgtc
     1981 gccgcagttg ataagagtgt ctacctgctc aggtctgggt tccggctgac tcctgcccag
     2041 gttttccagg aactggaaga ttatgatgtt tctgattcct ttggcgtgtc cagggaggat
     2101 ggtccttttt ggtgggctgg gctgacggca caacgacgcc ggcgctcctc tgtcttcccg
     2161 tggccttggg gcatcaccaa ggactctggg tttgccttca ccgaaacggg actggtggtg
     2221 atgaccgacc gagtgagcct gaaccaccgg caggacggtg gcctctacac cgatgaggct
     2281 gtccccgctt tccagcccca cacagggagc ctggtggcag tggctccttc caggcacccc
     2341 cccagaacag agaagagaaa aaggactttc ttccccgaaa catggatttg gcattgtctc
     2401 aacatcagtg acccatctgg tgaggggaca ctcagtgtga aggtcccgga ctccatcacc
     2461 agctgggtgg gtgaggccgt ggccctgtcc acctctcagg gcttaggcat cgccgagccc
     2521 tccctgctga agaccttcaa gcccttcttc gtggacttca tgctccccgc tctcatcatc
     2581 cgtggggagc aggtcaagat cccgctcagt gtctacaact acatgggcac ctgcgctgag
     2641 gtgtacatga agctctcggt tcccaagggc atccagtttg ttgggcatcc tggcaaacgc
     2701 catgtgacca agaagatgtg tgtggccccc ggggaggctg agcccatctg ggtcgttctg
     2761 tccttcagcg acctgggact caacaacatc acggccaaag cccttgctta cggagacaca
     2821 aattgctgcc gggatgggag gtccagcaaa caccctgagg agaatcacgc cgacaggagg
     2881 gtccccatcg gggtggatca cgtcaggcgc agtgtgatgg ttgaggcgga aggagtcccc
     2941 cgggcgtaca cctacagcgc attcttctgt cccagtgaga gagtccacat ctccaccccc
     3001 aacaagtatg agttccagta tgtgcagcgg ccactgcgcc tcacccgctt tgatgtggct
     3061 gtgcgagctc acaatgatgc ccgtgtggcc ttgtcttctg ggccccagga cacagcaggc
     3121 atgatcgaga tcgtcctggg ggggcatcag aacaccaggt catggatctc caccagcaag
     3181 atgggagagc ccgtggccag tgcacacacg gccaagatcc tctcctggga tgaattcaga
     3241 acattctgga tcagctggcg tggtggcctt atccaggttg gccatggtcc agagccatcc
     3301 aatgagtctg tcattgtggc ctggaccctc ccgaggccac cagaggtcca gttcattggc
     3361 ttttccaccg gctggggctc catgggtgaa ttccgaatct ggaggaagat ggaggtggac
     3421 gagagctaca gcgaggcctt caccctgggg gtcccacacg gcgccatccc tgggtctgag
     3481 cgagccaccg cctccatcat cggggacgtc atggggccaa ccctgaacca cctcaacaac
     3541 ctcctgcggc tgccgtttgg ctgtggagag cagaacatga tccactttgc acccaacgtc
     3601 tttgtcttga agtatcttca gaaaacccag cagctcagcc ctgaggtgga gagagagacc
     3661 accgactacc tagtacaagg ctaccagcgc cagctgacct acaagcgcca ggatggctcc
     3721 tacagcgcgt ttggggagcg ggacgcatcg gggagcatgt ggctcacagc ctttgtcctg
     3781 aagtccttcg cacaggctcg cagctttatc ttcgtggacc cccgggagct ggctgccgcc
     3841 aagagctgga tcatccagca gcagcaggcc gatggctcct tcctggccgt gggcagggtc
     3901 ctgaacaagg acatccaggg tgggatccac ggcactgtcc cgctgacagc ctacgtggtg
     3961 gttgctctcc tggaaacagg cacagcctca gaggaggaga gaggctccac tgacaaagcg
     4021 aggcacttcc tggagtctgc tgcgcccctg gccatggacc cttatagctg tgccctgact
     4081 acctacgcgc tgaccctgct ccgcagcccg gcagcccctg aggcactgcg caagctccgt
     4141 agcctggcca tcatgcgaga tggggtcacc cactggagcc tgtcaaattc ctgggacgtg
     4201 gacaagggca cattcttgag cttcagtgac agggtctctc agtcagtggt ctcggccgag
     4261 gtggaaatga cagcctacgc ccttctgacc tacactctgc tgggtgacgt ggctgccgcc
     4321 ctgcctgtgg tgaagtggct gtcccagcag cgaaatgcac ttgggggctt ctcctccact
     4381 caggacacct gcgtggctct gcaggccttg gctgaatatg ccatcttgtc ctatgctgga
     4441 ggcatcaacc tcactgtctc cctggcctcc accaacctgg actaccagga aaccttcgag
     4501 ctgcacagga ccaaccagaa ggttctgcag acagcagcga tccccagcct ccccacgggg
     4561 ctgtttgtga gtgccaaggg ggacggctgc tgcctgatgc agattgatgt cacctacaat
     4621 gtgcctgacc cggtggccaa gccagctttc cagctgctcg taagcctcca ggagcctgag
     4681 gcccagggac gcccgccccc catgcctgcc tccgcagctg agggttcccg aggagactgg
     4741 cccccagctg acgatgatga cccagcggcc gatcagcatc accaggaata caaggtgatg
     4801 ctggaggtgt gcaccaggtg gctgcatgca gggtcttcca atatggctgt cctggaggtg
     4861 cccctgctgt caggcttccg ggcagacatc gagagcctgg agcagctgct ccttgacaag
     4921 cacatgggga tgaagaggta tgaagtggct ggacgccgag tgctcttcta ctttgatgag
     4981 atccccagcc ggtgcctgac gtgcgtgcgg ttccgtgctc tccgggagtg cgtggtgggc
     5041 aggacgtcgg cgctgccagt ctccgtgtac gactactacg aacccgcctt cgaggccact
     5101 cgcttctaca acgtcagcac ccacagccca ctcgcccggg aactgtgcgc cggacccgcg
     5161 tgcaacgaag tggagcgcgc ccctgcccgg ggcccgggct ggttccccgg cgagtcgggc
     5221 cctgccgtgg cccctgagga gggggcggcg atcgcgcgat gcggctgcga ccacgactgc
     5281 ggcgcccagg ggaacccggt gtgcggctcc gacggggtgg tctacgccag cgcctgccgc
     5341 ctgcgggagg ccgcctgccg ccaggccgcg cccctggagc ccgcgcctcc cagctgctgc
     5401 gccctcgagc agcggctgcc ggcctcgtcg tcctccacct acggggatga cctggcttct
     5461 gtggccccgg ggcctttaca gcaggacgtg aagctgaatg gagccggcct tgaggtggag
     5521 gactcagacc ctgagcctga aggggaggcg gaggacaggg tcacagccgg gcctcggcct
     5581 cctgtgagca gcgggaacct ggaaagcagc acccagagcg ccagcccgtt ccacagatgg
     5641 ggccagactc cggcccctca gagacatagt ggccgggtgg tgggggccca caggccaggg
     5701 cttctgagcc ctgtcttcgt ctacagccca gcctttcaga gtggtgggga ggagggttta
     5761 tggatgtcaa acacctgcac cttgagataa tcctacaacc acatgcagtt gtgggaccgc
     5821 agtttggtcc tggggaccat tcatacccac acacccagct tgtgcctgtg gttaacatct
     5881 cagaaaactc tggtaaatga tcactccagg atattgacaa gaatacacgt tactgatctt
     5941 actcaca
//
