LOCUS       NM_007074               1623 bp    mRNA    linear   PRI 07-APR-2024
DEFINITION  Homo sapiens coronin 1A (CORO1A), transcript variant 2, mRNA.
ACCESSION   NM_007074
VERSION     NM_007074.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1623)
  AUTHORS   Wang,Y., Ma,L., Jia,S., Liu,D., Gu,H., Wei,X., Ma,W., Luo,W.,
            Bai,Y., Wang,W. and Yuan,Z.
  TITLE     Serum exosomal coronin 1A and dynamin 2 as neural tube defect
            biomarkers
  JOURNAL   J Mol Med (Berl) 100 (9), 1307-1319 (2022)
   PUBMED   35915349
  REMARK    GeneRIF: Serum exosomal coronin 1A and dynamin 2 as neural tube
            defect biomarkers.
REFERENCE   2  (bases 1 to 1623)
  AUTHORS   Min,F., Fan,C., Zeng,Y., He,N., Zeng,T., Qin,B. and Shi,Y.
  TITLE     Carbamazepine-modified HLA-A*24:02-bound peptidome: Implication of
            CORO1A in skin rash
  JOURNAL   Int Immunopharmacol 109, 108804 (2022)
   PUBMED   35526384
  REMARK    GeneRIF: Carbamazepine-modified HLA-A*24:02-bound peptidome:
            Implication of CORO1A in skin rash.
REFERENCE   3  (bases 1 to 1623)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   4  (bases 1 to 1623)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   5  (bases 1 to 1623)
  AUTHORS   Fragoza,R., Das,J., Wierbowski,S.D., Liang,J., Tran,T.N., Liang,S.,
            Beltran,J.F., Rivera-Erick,C.A., Ye,K., Wang,T.Y., Yao,L., Mort,M.,
            Stenson,P.D., Cooper,D.N., Wei,X., Keinan,A., Schimenti,J.C.,
            Clark,A.G. and Yu,H.
  TITLE     Extensive disruption of protein interactions by genetic variants
            across the allele frequency spectrum in human populations
  JOURNAL   Nat Commun 10 (1), 4141 (2019)
   PUBMED   31515488
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1623)
  AUTHORS   Vanguri,V.K., Wang,S., Godyna,S., Ranganathan,S. and Liau,G.
  TITLE     Thrombospondin-1 binds to polyhistidine with high affinity and
            specificity
  JOURNAL   Biochem J 347 (Pt 2), 469-473 (2000)
   PUBMED   10749676
REFERENCE   7  (bases 1 to 1623)
  AUTHORS   Ferrari,G., Langen,H., Naito,M. and Pieters,J.
  TITLE     A coat protein on phagosomes involved in the intracellular survival
            of mycobacteria
  JOURNAL   Cell 97 (4), 435-447 (1999)
   PUBMED   10338208
REFERENCE   8  (bases 1 to 1623)
  AUTHORS   Okumura,M., Kung,C., Wong,S., Rodgers,M. and Thomas,M.L.
  TITLE     Definition of family of coronin-related proteins conserved between
            humans and mice: close genetic linkage between coronin-2 and
            CD45-associated protein
  JOURNAL   DNA Cell Biol 17 (9), 779-787 (1998)
   PUBMED   9778037
REFERENCE   9  (bases 1 to 1623)
  AUTHORS   Grogan,A., Reeves,E., Keep,N., Wientjes,F., Totty,N.F.,
            Burlingame,A.L., Hsuan,J.J. and Segal,A.W.
  TITLE     Cytosolic phox proteins interact with and regulate the assembly of
            coronin in neutrophils
  JOURNAL   J Cell Sci 110 (Pt 24), 3071-3081 (1997)
   PUBMED   9365277
REFERENCE   10 (bases 1 to 1623)
  AUTHORS   Suzuki,K., Nishihata,J., Arai,Y., Honma,N., Yamamoto,K., Irimura,T.
            and Toyoshima,S.
  TITLE     Molecular cloning of a novel actin-binding protein, p57, with a WD
            repeat and a leucine zipper motif
  JOURNAL   FEBS Lett 364 (3), 283-288 (1995)
   PUBMED   7758584
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BC110374.1 and U34690.1.
            
            On Nov 19, 2019 this sequence version replaced NM_007074.3.
            
            Summary: This gene encodes a member of the WD repeat protein
            family. WD repeats are minimally conserved regions of approximately
            40 amino acids typically bracketed by gly-his and trp-asp (GH-WD),
            which may facilitate formation of heterotrimeric or multiprotein
            complexes. Members of this family are involved in a variety of
            cellular processes, including cell cycle progression, signal
            transduction, apoptosis, and gene regulation. Alternative splicing
            results in multiple transcript variants. A related pseudogene has
            been defined on chromosome 16. [provided by RefSeq, Sep 2010].
            
            Transcript Variant: This variant (2) differs in the 5' UTR compared
            to variant 1. Both variants 1 and 2 encode the same protein.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC110374.1, AF495470.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000219150.10/ ENSP00000219150.6
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-460               BC110374.1         10-469
            461-461             U34690.1           428-428
            462-1623            BC110374.1         471-1632
FEATURES             Location/Qualifiers
     source          1..1623
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16p11.2"
     gene            1..1623
                     /gene="CORO1A"
                     /gene_synonym="CLABP; CLIPINA; HCORO1; IMD8; p57; TACO"
                     /note="coronin 1A"
                     /db_xref="GeneID:11151"
                     /db_xref="HGNC:HGNC:2252"
                     /db_xref="MIM:605000"
     exon            1..124
                     /gene="CORO1A"
                     /gene_synonym="CLABP; CLIPINA; HCORO1; IMD8; p57; TACO"
                     /inference="alignment:Splign:2.1.0"
     exon            125..323
                     /gene="CORO1A"
                     /gene_synonym="CLABP; CLIPINA; HCORO1; IMD8; p57; TACO"
                     /inference="alignment:Splign:2.1.0"
     CDS             126..1511
                     /gene="CORO1A"
                     /gene_synonym="CLABP; CLIPINA; HCORO1; IMD8; p57; TACO"
                     /note="coronin-1; clipin-A; coronin, actin binding
                     protein, 1A; coronin-like protein A; coronin-like protein
                     p57; tryptophan aspartate-containing coat protein"
                     /codon_start=1
                     /product="coronin-1A"
                     /protein_id="NP_009005.1"
                     /db_xref="CCDS:CCDS10673.1"
                     /db_xref="GeneID:11151"
                     /db_xref="HGNC:HGNC:2252"
                     /db_xref="MIM:605000"
                     /translation="MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNP
                     KFVALICEASGGGAFLVLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSE
                     DCTVMVWEIPDGGLMLPLREPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWD
                     VGTGAAMLTLGPEVHPDTIYSVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPH
                     EGTRPVRAVFVSEGKILTTGFSRMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFD
                     PDTNIVYLCGKGDSSIRYFEITSEAPFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEI
                     ARFYKLHERRCEPIAMTVPRKSDLFQEDLYPPTAGPDPALTAEEWLGGRDAGPLLISL
                     KDGYVPPKSRELRVNRGLDTGRRRAAPEASGTPSSDAVSRLEEEMRKLQATVQELQKR
                     LDRLEETVQAK"
     exon            324..446
                     /gene="CORO1A"
                     /gene_synonym="CLABP; CLIPINA; HCORO1; IMD8; p57; TACO"
                     /inference="alignment:Splign:2.1.0"
     exon            447..576
                     /gene="CORO1A"
                     /gene_synonym="CLABP; CLIPINA; HCORO1; IMD8; p57; TACO"
                     /inference="alignment:Splign:2.1.0"
     exon            577..761
                     /gene="CORO1A"
                     /gene_synonym="CLABP; CLIPINA; HCORO1; IMD8; p57; TACO"
                     /inference="alignment:Splign:2.1.0"
     exon            762..881
                     /gene="CORO1A"
                     /gene_synonym="CLABP; CLIPINA; HCORO1; IMD8; p57; TACO"
                     /inference="alignment:Splign:2.1.0"
     exon            882..986
                     /gene="CORO1A"
                     /gene_synonym="CLABP; CLIPINA; HCORO1; IMD8; p57; TACO"
                     /inference="alignment:Splign:2.1.0"
     exon            987..1132
                     /gene="CORO1A"
                     /gene_synonym="CLABP; CLIPINA; HCORO1; IMD8; p57; TACO"
                     /inference="alignment:Splign:2.1.0"
     exon            1133..1190
                     /gene="CORO1A"
                     /gene_synonym="CLABP; CLIPINA; HCORO1; IMD8; p57; TACO"
                     /inference="alignment:Splign:2.1.0"
     exon            1191..1406
                     /gene="CORO1A"
                     /gene_synonym="CLABP; CLIPINA; HCORO1; IMD8; p57; TACO"
                     /inference="alignment:Splign:2.1.0"
     exon            1407..1623
                     /gene="CORO1A"
                     /gene_synonym="CLABP; CLIPINA; HCORO1; IMD8; p57; TACO"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 attcattgtc ttgacaagag catcttcagc gggcgagtcc ccggctcctc cagctccttc
       61 ctcctcttcc tcctcctcct ccacctccgg cttttggggg atcactgtcc tctctcggca
      121 gcagaatgag ccggcaggtg gtccgctcca gcaagttccg ccacgtgttt ggacagccgg
      181 ccaaggccga ccagtgctat gaagatgtgc gcgtctcaca gaccacctgg gacagtggct
      241 tctgtgctgt caaccctaag tttgtggccc tgatctgtga ggccagcggg ggaggggcct
      301 tcctggtgct gcccctgggc aagactggac gtgtggacaa gaatgcgccc acggtctgtg
      361 gccacacagc ccctgtgcta gacatcgcct ggtgcccgca caatgacaac gtcattgcca
      421 gtggctccga ggactgcaca gtcatggtgt gggagatccc agatgggggc ctgatgctgc
      481 ccctgcggga gcccgtcgtc accctggagg gccacaccaa gcgtgtgggc attgtggcct
      541 ggcacaccac agcccagaac gtgctgctca gtgcaggttg tgacaacgtg atcatggtgt
      601 gggacgtggg cactggggcg gccatgctga cactgggccc agaggtgcac ccagacacga
      661 tctacagtgt ggactggagc cgagatggag gcctcatttg tacctcctgc cgtgacaagc
      721 gcgtgcgcat catcgagccc cgcaaaggca ctgtcgtagc tgagaaggac cgtccccacg
      781 aggggacccg gcccgtgcgt gcagtgttcg tgtcggaggg gaagatcctg accacgggct
      841 tcagccgcat gagtgagcgg caggtggcgc tgtgggacac aaagcacctg gaggagccgc
      901 tgtccctgca ggagctggac accagcagcg gtgtcctgct gcccttcttt gaccctgaca
      961 ccaacatcgt ctacctctgt ggcaagggtg acagctcaat ccggtacttt gagatcactt
     1021 ccgaggcccc tttcctgcac tatctctcca tgttcagttc caaggagtcc cagcggggca
     1081 tgggctacat gcccaaacgt ggcctggagg tgaacaagtg tgagatcgcc aggttctaca
     1141 agctgcacga gcggaggtgt gagcccattg ccatgacagt gcctcgaaag tcggacctgt
     1201 tccaggagga cctgtaccca cccaccgcag ggcccgaccc tgccctcacg gctgaggagt
     1261 ggctgggggg tcgggatgct gggcccctcc tcatctccct caaggatggc tacgtacccc
     1321 caaagagccg ggagctgagg gtcaaccggg gcctggacac cgggcgcagg agggcagcac
     1381 cagaggccag tggcactccc agctcggatg ccgtgtctcg gctggaggag gagatgcgga
     1441 agctccaggc cacggtgcag gagctccaga agcgcttgga caggctggag gagacagtcc
     1501 aggccaagta gagccccgca gggcctccag cagggtcagc cattcacacc catccactca
     1561 cctcccattc ccagccacat ggcagagaaa aaaatcataa taaaatggct ttattttctg
     1621 gta
//
