LOCUS       XM_047427793            2394 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens COP1 E3 ubiquitin ligase (COP1), transcript
            variant X20, mRNA.
ACCESSION   XM_047427793
VERSION     XM_047427793.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2394
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..2394
                     /gene="COP1"
                     /gene_synonym="CFAP78; FAP78; RFWD2; RNF200"
                     /note="COP1 E3 ubiquitin ligase; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 32
                     ESTs, 461 long SRA reads, 1 Protein, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 37 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:64326"
                     /db_xref="HGNC:HGNC:17440"
                     /db_xref="MIM:608067"
     CDS             309..2072
                     /gene="COP1"
                     /gene_synonym="CFAP78; FAP78; RFWD2; RNF200"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase COP1 isoform X20"
                     /protein_id="XP_047283749.1"
                     /db_xref="GeneID:64326"
                     /db_xref="HGNC:HGNC:17440"
                     /db_xref="MIM:608067"
                     /translation="MSGSRQAGSGSAGTSPGSSAASSVTSASSSLSSSPSPPSVAVSA
                     AALVSGGVAQAAGSGGLGGPVRPVLVAPAVSGSGGGAVSTGLSRHSCAARPSAGVGGS
                     SSSLGSGSRKRPLLAPLCNGLINSYEDKSNDFVCPICFDMIEEAYMTKCGHSFWNHMQ
                     PNYRFLWNSSRLQEEIRESSIIDSTEYSQPPGFSGSSQTKKQPWYNSTLASRRKRLTA
                     HFEDLEQCYFSTRMSRISDDSRTASQLDEFQECLSKFTRYNSVRPLATLSYASDLYNG
                     SSIVSSIEFDRDCDYFAIAGVTKKIKVYEYDTVIQDAVDIHYPENEMTCNSKISCISW
                     SSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDA
                     KVKLWSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMV
                     FKGHRKAVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNG
                     DYIACGSENNSLYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEFVSAVCWRALPD
                     GESNVLIAANSQGTIKVLELV"
ORIGIN      
        1 gctcgcgcgc gcgcgcacgg ccggccacgg cgcgccgggg ttggctgcta cagggaccgc
       61 ggtggcggcg gcggcctcga cagcggtagt gccttctact ccgctttttt agtttcctcc
      121 gccccctccc gtgggacgct gttgtgtggc tgccttaaaa aaaaacgcaa ctttattgtt
      181 cctcagcccc acctccggct cggcgggcgt cctcaggatg cactgaggct gaggggaggg
      241 gaggcggcgg agggtcgagg tcgcggtccc tctcctccga gcgcccggct ggaggggagg
      301 gagtcacgat gtctggtagc cgccaggccg ggtcgggctc cgctgggaca agccccgggt
      361 cctcggcggc ctcctcggtg acttccgcct cctcgtcttt atcctcttcc ccgtcgccgc
      421 cttccgtggc ggtttcggcg gcagcgctgg tgtccggcgg ggtggcccag gccgccggct
      481 cgggcggcct cgggggcccg gtgcggcctg tgttggtggc gcccgccgta tcgggtagcg
      541 gcggcggggc ggtgtccacg ggcctgtccc ggcacagctg cgcggccagg cccagcgccg
      601 gcgtaggagg cagcagctcc agcctaggca gcggcagcag gaagcgacct ctcctcgccc
      661 ccctctgcaa cgggctcatc aactcctacg aggacaaaag caacgacttc gtatgcccca
      721 tctgctttga tatgattgaa gaagcataca tgacaaaatg tggccacagc ttttggaatc
      781 acatgcagcc caactacaga ttcttatgga attcctcaag gttgcaagaa gaaataagag
      841 agagtagtat tattgattcc acagaataca gccaacctcc aggtttcagt ggcagttctc
      901 agacaaagaa acagccttgg tataatagca cgttagcatc aagacgaaaa cgacttactg
      961 ctcattttga agacttggag cagtgttact tttctacaag gatgtctcgt atctcagatg
     1021 acagtcgaac tgcaagccag ttggatgaat ttcaggaatg cttgtccaag tttactcgat
     1081 ataattcagt acgaccttta gccacattgt catatgctag tgatctctat aatggttcca
     1141 gtatagtctc tagtattgaa tttgaccggg attgtgacta ttttgcgatt gctggagtta
     1201 caaagaagat taaagtctat gaatatgaca ctgtcatcca ggatgcagtg gatattcatt
     1261 accctgagaa tgaaatgacc tgcaattcga aaatcagctg tatcagttgg agtagttacc
     1321 ataagaacct gttagctagc agtgattatg aaggcactgt tattttatgg gatggattca
     1381 caggacagag gtcaaaggtc tatcaggagc atgagaagag gtgttggagt gttgacttta
     1441 atttgatgga tcctaaactc ttggcttcag gttctgatga tgcaaaagtg aagctgtggt
     1501 ctaccaatct agacaactca gtggcaagca ttgaggcaaa ggctaatgtg tgctgtgtta
     1561 aattcagccc ctcttccaga taccatttgg ctttcggctg tgcagatcac tgtgtccact
     1621 actatgatct tcgtaacact aaacagccaa tcatggtatt caaaggacac cgtaaagcag
     1681 tctcttatgc aaagtttgtg agtggtgagg aaattgtctc tgcctcaaca gacagtcagc
     1741 taaaactgtg gaatgtaggg aaaccatact gcctacgttc cttcaagggt catatcaatg
     1801 aaaaaaactt tgtaggcctg gcttccaatg gagattatat agcttgtgga agtgaaaata
     1861 actctctcta cctgtactat aaaggacttt ctaagacttt gctaactttt aagtttgata
     1921 cagtcaaaag tgttctcgac aaagaccgaa aagaagatga tacaaatgaa tttgttagtg
     1981 ctgtgtgctg gagggcacta ccagatgggg agtccaatgt gctgattgct gctaacagtc
     2041 agggtacaat taaggtgcta gaattggtat gaagggttaa ctcaagtcaa attgtacttg
     2101 atcctgctga aatacatctg cagctgacaa tgagagaaga aacagaaaat gtcatgtgat
     2161 gtctctcccc aaagtcatca tgggttttgg atttgttttg aatatttttt tctttttttc
     2221 ttttccctcc tttatgacct ttgggacatt gggaataccc agccaactct ccaccatcaa
     2281 tgtaactcca tggacattgc tgctcttggt ggtgttatct aatttttgtg atagggaaac
     2341 aaattctttt gaataaaaat aaataacaaa acaataaaag tttattgagc caca
//
