LOCUS       XM_011509881            2880 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens COP1 E3 ubiquitin ligase (COP1), transcript
            variant X7, mRNA.
ACCESSION   XM_011509881
VERSION     XM_011509881.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011509881.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2880
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..2880
                     /gene="COP1"
                     /gene_synonym="CFAP78; FAP78; RFWD2; RNF200"
                     /note="COP1 E3 ubiquitin ligase; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 1
                     mRNA, 35 ESTs, 529 long SRA reads, 2 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 37 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:64326"
                     /db_xref="HGNC:HGNC:17440"
                     /db_xref="MIM:608067"
     CDS             309..2558
                     /gene="COP1"
                     /gene_synonym="CFAP78; FAP78; RFWD2; RNF200"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase COP1 isoform X7"
                     /protein_id="XP_011508183.1"
                     /db_xref="GeneID:64326"
                     /db_xref="HGNC:HGNC:17440"
                     /db_xref="MIM:608067"
                     /translation="MSGSRQAGSGSAGTSPGSSAASSVTSASSSLSSSPSPPSVAVSA
                     AALVSGGVAQAAGSGGLGGPVRPVLVAPAVSGSGGGAVSTGLSRHSCAARPSAGVGGS
                     SSSLGSGSRKRPLLAPLCNGLINSYEDKSNDFVCPICFDMIEEAYMTKCGHSFCYKCI
                     HQSLEDNNRCPKCNYVVDNIDHLYPNFLVNELILKQKQRFEEKRFKLDHSVSSTNGHR
                     WQIFQDWLGTDQDNLDLANVNLMLELLVQKKKQLEAESHAAQLQILMEFLKVARRNKR
                     EQLEQIQKELSVLEEDIKRVEEMSGLYSPVSEDSTVPQFEAPSPSHSLEFSSDMHRIF
                     VNGILIISIIDSTEYSQPPGFSGSSQTKKQPWYNSTLASRRKRLTAHFEDLEQCYFST
                     RMSRISDDSRTASQLDEFQECLSKFTRYNSVRPLATLSYASDLYNGSSIVSSIEFDRD
                     CDYFAIAGVTKKIKVYEYDTVIQDAVDIHYPENEMTCNSKISCISWSSYHKNLLASSD
                     YEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKLWSTNLDNS
                     VASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRKAVSYAK
                     FVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSENNSL
                     YLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEFVSAVCWRALPDGESNVLIAANSQ
                     GTIKVLELV"
ORIGIN      
        1 gctcgcgcgc gcgcgcacgg ccggccacgg cgcgccgggg ttggctgcta cagggaccgc
       61 ggtggcggcg gcggcctcga cagcggtagt gccttctact ccgctttttt agtttcctcc
      121 gccccctccc gtgggacgct gttgtgtggc tgccttaaaa aaaaacgcaa ctttattgtt
      181 cctcagcccc acctccggct cggcgggcgt cctcaggatg cactgaggct gaggggaggg
      241 gaggcggcgg agggtcgagg tcgcggtccc tctcctccga gcgcccggct ggaggggagg
      301 gagtcacgat gtctggtagc cgccaggccg ggtcgggctc cgctgggaca agccccgggt
      361 cctcggcggc ctcctcggtg acttccgcct cctcgtcttt atcctcttcc ccgtcgccgc
      421 cttccgtggc ggtttcggcg gcagcgctgg tgtccggcgg ggtggcccag gccgccggct
      481 cgggcggcct cgggggcccg gtgcggcctg tgttggtggc gcccgccgta tcgggtagcg
      541 gcggcggggc ggtgtccacg ggcctgtccc ggcacagctg cgcggccagg cccagcgccg
      601 gcgtaggagg cagcagctcc agcctaggca gcggcagcag gaagcgacct ctcctcgccc
      661 ccctctgcaa cgggctcatc aactcctacg aggacaaaag caacgacttc gtatgcccca
      721 tctgctttga tatgattgaa gaagcataca tgacaaaatg tggccacagc ttttgctaca
      781 agtgtattca tcagagtttg gaggacaata atagatgtcc caagtgtaac tatgttgtgg
      841 acaatattga ccatctgtat cctaatttct tggtgaatga actcattctt aaacagaagc
      901 aaagatttga ggaaaagagg ttcaaattgg accactcagt gagtagcacc aatggccaca
      961 ggtggcagat atttcaagat tggttgggaa ctgaccaaga taaccttgat ttggccaatg
     1021 tcaatcttat gttggagtta ctagtgcaga agaagaaaca actggaagca gaatcacatg
     1081 cagcccaact acagattctt atggaattcc tcaaggttgc aagaagaaat aagagagagc
     1141 aactggaaca gatccagaag gagctaagtg ttttggaaga ggatattaag agagtggaag
     1201 aaatgagtgg cttatactct cctgtcagtg aggatagcac agtgcctcaa tttgaagctc
     1261 cttctccatc acacagcctt gaattcagtt ctgatatgca caggatcttt gtcaatggaa
     1321 tacttattat tagtattatt gattccacag aatacagcca acctccaggt ttcagtggca
     1381 gttctcagac aaagaaacag ccttggtata atagcacgtt agcatcaaga cgaaaacgac
     1441 ttactgctca ttttgaagac ttggagcagt gttacttttc tacaaggatg tctcgtatct
     1501 cagatgacag tcgaactgca agccagttgg atgaatttca ggaatgcttg tccaagttta
     1561 ctcgatataa ttcagtacga cctttagcca cattgtcata tgctagtgat ctctataatg
     1621 gttccagtat agtctctagt attgaatttg accgggattg tgactatttt gcgattgctg
     1681 gagttacaaa gaagattaaa gtctatgaat atgacactgt catccaggat gcagtggata
     1741 ttcattaccc tgagaatgaa atgacctgca attcgaaaat cagctgtatc agttggagta
     1801 gttaccataa gaacctgtta gctagcagtg attatgaagg cactgttatt ttatgggatg
     1861 gattcacagg acagaggtca aaggtctatc aggagcatga gaagaggtgt tggagtgttg
     1921 actttaattt gatggatcct aaactcttgg cttcaggttc tgatgatgca aaagtgaagc
     1981 tgtggtctac caatctagac aactcagtgg caagcattga ggcaaaggct aatgtgtgct
     2041 gtgttaaatt cagcccctct tccagatacc atttggcttt cggctgtgca gatcactgtg
     2101 tccactacta tgatcttcgt aacactaaac agccaatcat ggtattcaaa ggacaccgta
     2161 aagcagtctc ttatgcaaag tttgtgagtg gtgaggaaat tgtctctgcc tcaacagaca
     2221 gtcagctaaa actgtggaat gtagggaaac catactgcct acgttccttc aagggtcata
     2281 tcaatgaaaa aaactttgta ggcctggctt ccaatggaga ttatatagct tgtggaagtg
     2341 aaaataactc tctctacctg tactataaag gactttctaa gactttgcta acttttaagt
     2401 ttgatacagt caaaagtgtt ctcgacaaag accgaaaaga agatgataca aatgaatttg
     2461 ttagtgctgt gtgctggagg gcactaccag atggggagtc caatgtgctg attgctgcta
     2521 acagtcaggg tacaattaag gtgctagaat tggtatgaag ggttaactca agtcaaattg
     2581 tacttgatcc tgctgaaata catctgcagc tgacaatgag agaagaaaca gaaaatgtca
     2641 tgtgatgtct ctccccaaag tcatcatggg ttttggattt gttttgaata tttttttctt
     2701 tttttctttt ccctccttta tgacctttgg gacattggga atacccagcc aactctccac
     2761 catcaatgta actccatgga cattgctgct cttggtggtg ttatctaatt tttgtgatag
     2821 ggaaacaaat tcttttgaat aaaaataaat aacaaaacaa taaaagttta ttgagccaca
//
