LOCUS       XM_017005691            7510 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens collagen type VII alpha 1 chain (COL7A1),
            transcript variant X8, mRNA.
ACCESSION   XM_017005691
VERSION     XM_017005691.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000003.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017005691.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7510
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
     gene            1..7510
                     /gene="COL7A1"
                     /gene_synonym="EBD1; EBDCT; EBR1; NDNC8"
                     /note="collagen type VII alpha 1 chain; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 6 mRNAs, 5 ESTs, 62 long SRA reads, 3 Proteins, and
                     99% coverage of the annotated genomic feature by RNAseq
                     alignments, including 4 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:1294"
                     /db_xref="HGNC:HGNC:2214"
                     /db_xref="MIM:120120"
     CDS             64..7464
                     /gene="COL7A1"
                     /gene_synonym="EBD1; EBDCT; EBR1; NDNC8"
                     /codon_start=1
                     /product="collagen alpha-1(VII) chain isoform X4"
                     /protein_id="XP_016861180.1"
                     /db_xref="GeneID:1294"
                     /db_xref="HGNC:HGNC:2214"
                     /db_xref="MIM:120120"
                     /translation="MTLRLLVAALCAGILAEAPRVRAQHRERVTCTRLYAADIVFLLD
                     GSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQYSDDPRTEFGLDALGSGGD
                     VIRAIRELSYKGGNTRTGAAILHVADHVFLPQLARPGVPKVCILITDGKSQDLVDTAA
                     QRLKGQGVKLFAVGIKNADPEELKRVASQPTSDFFFFVNDFSILRTLLPLVSRRVCTT
                     AGGVPVTRPPDDSTSAPRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQPL
                     PSERQEVNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGPELT
                     IQNTTAHSLLVAWRSVPGATGYRVTWRVLSGGPTQQQELGPGQGSVLLRDLEPGTDYE
                     VTVSTLFGRSVGPATSLMARTDASVEQTLRPVILGPTSILLSWNLVPEARGYRLEWRR
                     ETGLEPPQKVVLPSDVTRYQLDGLQPGTEYRLTLYTLLEGHEVATPATVVPTGPELPV
                     SPVTDLQATELPGQRVRVSWSPVPGATQYRIIVRSTQGVERTLVLPGSQTAFDLDDVQ
                     AGLSYTVRVSARVGPREGSASVLTVRREPETPLAVPGLRVVVSDATRVRVAWGPVPGA
                     SGFRISWSTGSGPESSQTLPPDSTATDITGLQPGTTYQVAVSVLRGREEGPAAVIVAR
                     TDPLGPVRTVHVTQASSSSVTITWTRVPGATGYRVSWHSAHGPEKSQLVSGEATVAEL
                     DGLEPDTEYTVHVRAHVAGVDGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVG
                     VTGATAYRLAWGRSEGGPMRHQILPGNTDSAEIRGLEGGVSYSVRVTALVGDREGTPV
                     SIVVTTPPEAPPALGTLHVVQRGEHSLRLRWEPVPRAQGFLLHWQPEGGQEQSRVLGP
                     ELSSYHLDGLEPATQYRVRLSVLGPAGEGPSAEVTARTESPRVPSIELRVVDTSIDSV
                     TLAWTPVSRASSYILSWRPLRGPGQEVPGSPQTLPGISSSQRVTGLEPGVSYIFSLTP
                     VLDGVRGPEASVTQTPVCPRGLADVVFLPHATQDNAHRAEATRRVLERLVLALGPLGP
                     QAVQVGLLSYSHRPSPLFPLNGSHDLGIILQRIRDMPYMDPSGNNLGTAVVTAHRYML
                     APDAPGRRQHVPGVMVLLVDEPLRGDIFSPIREAQASGLNVVMLGMAGADPEQLRRLA
                     PGMDSVQTFFAVDDGPSLDQAVSGLATALCQASFTTQPRPEPCPVYCPKGQKGEPGEM
                     GLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPG
                     APGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGP
                     RGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQG
                     PVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEK
                     GERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGP
                     KGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSG
                     PPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGP
                     VGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQ
                     EGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLD
                     GKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNG
                     KNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQ
                     GFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALRE
                     IVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGP
                     PGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGR
                     DGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRG
                     VPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGA
                     PGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPG
                     QVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLP
                     GAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGP
                     KGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGSGRPPR
                     ERRNPRTPGATWTTGVSGTTWGLWTQRRQAELPSSQLLPLISNL"
ORIGIN      
        1 gacttttctc tgctctgccc gagagactgc agcggcggcg gcgggagcgg gcggacgcgc
       61 aggatgacgc tgcggcttct ggtggccgcg ctctgcgccg ggatcctggc agaggcgccc
      121 cgagtgcgag cccagcacag ggagagagtg acctgcacgc gcctttacgc cgctgacatt
      181 gtgttcttac tggatggctc ctcatccatt ggccgcagca atttccgcga ggtccgcagc
      241 tttctcgaag ggctggtgct gcctttctct ggagcagcca gtgcacaggg tgtgcgcttt
      301 gccacagtgc agtacagcga tgacccacgg acagagttcg gcctggatgc acttggctct
      361 gggggtgatg tgatccgcgc catccgtgag cttagctaca aggggggcaa cactcgcaca
      421 ggggctgcaa ttctccatgt ggctgaccat gtcttcctgc cccagctggc ccgacctggt
      481 gtccccaagg tctgcatcct gatcacagac gggaagtccc aggacctggt ggacacagct
      541 gcccaaaggc tgaaggggca gggggtcaag ctatttgctg tggggatcaa gaatgctgac
      601 cctgaggagc tgaagcgagt tgcctcacag cccaccagtg acttcttctt cttcgtcaat
      661 gacttcagca tcttgaggac actactgccc ctcgtttccc ggagagtgtg cacgactgct
      721 ggtggcgtgc ctgtgacccg acctccggat gactcgacct ctgctccacg agacctggtg
      781 ctgtctgagc caagcagcca atccttgaga gtacagtgga cagcggccag tggccctgtg
      841 actggctaca aggtccagta cactcctctg acggggctgg gacagccact gccgagtgag
      901 cggcaggagg tgaacgtccc agctggtgag accagtgtgc ggctgcgggg tctccggcca
      961 ctgaccgagt accaagtgac tgtgattgcc ctctacgcca acagcatcgg ggaggctgtg
     1021 agcgggacag ctcggaccac tgccctagaa gggccggaac tgaccatcca gaataccaca
     1081 gcccacagcc tcctggtggc ctggcggagt gtgccaggtg ccactggcta ccgtgtgaca
     1141 tggcgggtcc tcagtggtgg gcccacacag cagcaggagc tgggccctgg gcagggttca
     1201 gtgttgctgc gtgacttgga gcctggcacg gactatgagg tgaccgtgag caccctattt
     1261 ggccgcagtg tggggcccgc cacttccctg atggctcgca ctgacgcttc tgttgagcag
     1321 accctgcgcc cggtcatcct gggccccaca tccatcctcc tttcctggaa cttggtgcct
     1381 gaggcccgtg gctaccggtt ggaatggcgg cgtgagactg gcttggagcc accgcagaag
     1441 gtggtactgc cctctgatgt gacccgctac cagttggatg ggctgcagcc gggcactgag
     1501 taccgcctca cactctacac tctgctggag ggccacgagg tggccacccc tgcaaccgtg
     1561 gttcccactg gaccagagct gcctgtgagc cctgtaacag acctgcaagc caccgagctg
     1621 cccgggcagc gggtgcgagt gtcctggagc ccagtccctg gtgccaccca gtaccgcatc
     1681 attgtgcgca gcacccaggg ggttgagcgg accctggtgc ttcctgggag tcagacagca
     1741 ttcgacttgg atgacgttca ggctgggctt agctacactg tgcgggtgtc tgctcgagtg
     1801 ggtccccgtg agggcagtgc cagtgtcctc actgtccgcc gggagccgga aactccactt
     1861 gctgttccag ggctgcgggt tgtggtgtca gatgcaacgc gagtgagggt ggcctgggga
     1921 cccgtccctg gagccagtgg atttcggatt agctggagca caggcagtgg tccggagtcc
     1981 agccagacac tgcccccaga ctctactgcc acagacatca cagggctgca gcctggaacc
     2041 acctaccagg tggctgtgtc ggtactgcga ggcagagagg agggccctgc tgcagtcatc
     2101 gtggctcgaa cggacccact gggcccagtg aggacggtcc atgtgactca ggccagcagc
     2161 tcatctgtca ccattacctg gaccagggtt cctggcgcca caggatacag ggtttcctgg
     2221 cactcagccc acggcccaga gaaatcccag ttggtttctg gggaggccac ggtggctgag
     2281 ctggatggac tggagccaga tactgagtat acggtgcatg tgagggccca tgtggctggc
     2341 gtggatgggc cccctgcctc tgtggttgtg aggactgccc ctgagcctgt gggtcgtgtg
     2401 tcgaggctgc agatcctcaa tgcttccagc gacgttctac ggatcacctg ggtaggggtc
     2461 actggagcca cagcttacag actggcctgg ggccggagtg aaggcggccc catgaggcac
     2521 cagatactcc caggaaacac agactctgca gagatccggg gtctcgaagg tggagtcagc
     2581 tactcagtgc gagtgactgc acttgtcggg gaccgcgagg gcacacctgt ctccattgtt
     2641 gtcactacgc cgcctgaggc tccgccagcc ctggggacgc ttcacgtggt gcagcgcggg
     2701 gagcactcgc tgaggctgcg ctgggagccg gtgcccagag cgcagggctt ccttctgcac
     2761 tggcaacctg agggtggcca ggaacagtcc cgggtcctgg ggcccgagct cagcagctat
     2821 cacctggacg ggctggagcc agcgacacag taccgcgtga ggctgagtgt cctagggcca
     2881 gctggagaag ggccctctgc agaggtgact gcgcgcactg agtcacctcg tgttccaagc
     2941 attgaactac gtgtggtgga cacctcgatc gactcggtga ctttggcctg gactccagtg
     3001 tccagggcat ccagctacat cctatcctgg cggccactca gaggccctgg ccaggaagtg
     3061 cctgggtccc cgcagacact tccagggatc tcaagctccc agcgggtgac agggctagag
     3121 cctggcgtct cttacatctt ctccctgacg cctgtcctgg atggtgtgcg gggtcctgag
     3181 gcatctgtca cacagacgcc agtgtgcccc cgtggcctgg cggatgtggt gttcctacca
     3241 catgccactc aagacaatgc tcaccgtgcg gaggctacga ggagggtcct ggagcgtctg
     3301 gtgttggcac ttgggcctct tgggccacag gcagttcagg ttggcctgct gtcttacagt
     3361 catcggccct ccccactgtt cccactgaat ggctcccatg accttggcat tatcttgcaa
     3421 aggatccgtg acatgcccta catggaccca agtgggaaca acctgggcac agccgtggtc
     3481 acagctcaca gatacatgtt ggcaccagat gctcctgggc gccgccagca cgtaccaggg
     3541 gtgatggttc tgctagtgga tgaacccttg agaggtgaca tattcagccc catccgtgag
     3601 gcccaggctt ctgggcttaa tgtggtgatg ttgggaatgg ctggagcgga cccagagcag
     3661 ctgcgtcgct tggcgccggg tatggactct gtccagacct tcttcgccgt ggatgatggg
     3721 ccaagcctgg accaggcagt cagtggtctg gccacagccc tgtgtcaggc atccttcact
     3781 actcagcccc ggccagagcc ctgcccagtg tattgtccaa agggccagaa gggggaacct
     3841 ggagagatgg gcctgagagg acaagttggg cctcctggcg accctggcct cccgggcagg
     3901 accggtgctc ccggccccca ggggccccct ggaagtgcca ctgccaaggg cgagaggggc
     3961 ttccctggag cagatgggcg tccaggcagc cctggccgcg ccgggaatcc tgggacccct
     4021 ggagcccctg gcctaaaggg ctctccaggg ttgcctggcc ctcgtgggga cccgggagag
     4081 cgaggacctc gaggcccaaa gggggagccg ggggctcccg gacaagtcat cggaggtgaa
     4141 ggacctgggc ttcctgggcg gaaaggggac cctggaccat cgggcccccc tggacctcgt
     4201 ggaccactgg gggacccagg accccgtggc cccccagggc ttcctggaac agccatgaag
     4261 ggtgacaaag gcgatcgtgg ggagcggggt ccccctggac caggtgaagg tggcattgct
     4321 cctggggagc ctgggctgcc gggtcttccc ggaagccctg gaccccaagg ccccgttggc
     4381 ccccctggaa agaaaggaga aaaaggtgac tctgaggatg gagctccagg cctcccagga
     4441 caacctgggt ctccgggtga gcagggccca cggggacctc ctggagctat tggccccaaa
     4501 ggtgaccggg gctttccagg gcccctgggt gaggctggag agaagggcga acgtggaccc
     4561 ccaggcccag cgggatcccg ggggctgcca ggggttgctg gacgtcctgg agccaagggt
     4621 cctgaagggc caccaggacc cactggccgc caaggagaga agggggagcc tggtcgccct
     4681 ggggaccctg cagtggtggg acctgctgtt gctggaccca aaggagaaaa gggagatgtg
     4741 gggcccgctg ggcccagagg agctaccgga gtccaagggg aacggggccc acccggcttg
     4801 gttcttcctg gagaccctgg ccccaaggga gaccctggag accggggtcc cattggcctt
     4861 actggcagag caggaccccc aggtgactca gggcctcctg gagagaaggg agaccctggg
     4921 cggcctggcc ccccaggacc tgttggcccc cgaggacgag atggtgaagt tggagagaaa
     4981 ggtgacgagg gtcctccggg tgacccgggt ttgcctggaa aagcaggcga gcgtggcctt
     5041 cggggggcac ctggagttcg ggggcctgtg ggtgaaaagg gagaccaggg agatcctgga
     5101 gaggatggac gaaatggcag ccctggatca tctggaccca agggtgaccg tggggagccg
     5161 ggtcccccag gacccccggg acggctggta gacacaggac ctggagccag agagaaggga
     5221 gagcctgggg accgcggaca agagggtcct cgagggccca agggtgatcc tggcctccct
     5281 ggagcccctg gggaaagggg cattgaaggg tttcggggac ccccaggccc acagggggac
     5341 ccaggtgtcc gaggcccagc aggagaaaag ggtgaccggg gtccccctgg gctggatggc
     5401 cggagcggac tggatgggaa accaggagcc gctgggccct ctgggccgaa tggtgctgca
     5461 ggcaaagctg gggacccagg gagagacggg cttccaggcc tccgtggaga acagggcctc
     5521 cctggcccct ctggtccccc tggattaccg ggaaagccag gcgaggatgg caaacctggc
     5581 ctgaatggaa aaaacggaga acctggggac cctggagaag acgggaggaa gggagagaaa
     5641 ggagattcag gcgcctctgg gagagaaggt cgtgatggcc ccaagggtga gcgtggagct
     5701 cctggtatcc ttggacccca ggggcctcca ggcctcccag ggccagtggg ccctcctggc
     5761 cagggttttc ctggtgtccc aggaggcacg ggccccaagg gtgaccgtgg ggagactgga
     5821 tccaaagggg agcagggcct ccctggagag cgtggcctgc gaggagagcc tggaagtgtg
     5881 ccgaatgtgg atcggttgct ggaaactgct ggcatcaagg catctgccct gcgggagatc
     5941 gtggagacct gggatgagag ctctggtagc ttcctgcctg tgcccgaacg gcgtcgaggc
     6001 cccaaggggg actcaggcga acagggcccc ccaggcaagg agggccccat cggctttcct
     6061 ggagaacgcg ggctgaaggg cgaccgtgga gaccctggcc ctcaggggcc acctggtctg
     6121 gcccttgggg agaggggccc ccccgggcct tccggccttg ccggggagcc tggaaagcct
     6181 ggtattcccg ggctcccagg cagggctggg ggtgtgggag aggcaggaag gccaggagag
     6241 aggggagaac ggggagagaa aggagaacgt ggagaacagg gcagagatgg ccctcctgga
     6301 ctccctggaa cccctgggcc ccccggaccc cctggcccca aggtgtctgt ggatgagcca
     6361 ggtcctggac tctctggaga acagggaccc cctggactca agggtgctaa gggggagccg
     6421 ggcagcaatg gtgaccaagg tcccaaagga gacaggggtg tgccaggcat caaaggagac
     6481 cggggagagc ctggaccgag gggtcaggac ggcaacccgg gtctaccagg agagcgtggt
     6541 atggctgggc ctgaagggaa gccgggtctg cagggtccaa gaggcccccc tggcccagtg
     6601 ggtggtcatg gagaccctgg accacctggt gccccgggtc ttgctggccc tgcaggaccc
     6661 caaggacctt ctggcctgaa gggggagcct ggagagacag gacctccagg acggggcctg
     6721 actggaccta ctggagctgt gggacttcct ggaccccccg gcccttcagg ccttgtgggt
     6781 ccacaggggt ctccaggttt gcctggacaa gtgggggaga cagggaagcc gggagcccca
     6841 ggtcgagatg gtgccagtgg aaaagatgga gacagaggga gccctggtgt gccagggtca
     6901 ccaggtctgc ctggccctgt cggacctaaa ggagaacctg gccccacggg ggcccctgga
     6961 caggctgtgg tcgggctccc tggagcaaag ggagagaagg gagcccctgg aggccttgct
     7021 ggagacctgg tgggtgagcc gggagccaaa ggtgaccgag gactgccagg gccgcgaggc
     7081 gagaagggtg aagctggccg tgcaggggag cccggagacc ctggggaaga tggtcagaaa
     7141 ggggctccag gacccaaagg tttcaagggt gacccaggag tcggggtccc gggctcccct
     7201 gggcctcctg gccctccagg tgtgaaggga gatctgggcc tccctggcct gcccggtgct
     7261 cctggtgttg ttgggttccc gggtcagaca ggccctcgag gagagatggg gtctggcagg
     7321 ccccccaggg agagaaggaa tcccaggacc cctggggcca cctggaccac cggggtcagt
     7381 gggaccacct ggggcctctg gactcaaagg agacaagccg aactcccttc atcccagctc
     7441 ttgcctctga tttccaacct ctgagtcaat gaacctaatg tcaccatcca gggtgaagat
     7501 ggccgccccg
//
