LOCUS       XM_047447445            8898 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens collagen type VI alpha 6 chain (COL6A6),
            transcript variant X6, mRNA.
ACCESSION   XM_047447445
VERSION     XM_047447445.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000003.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8898
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
     gene            1..8898
                     /gene="COL6A6"
                     /note="collagen type VI alpha 6 chain; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 3 mRNAs, 19 ESTs, 7 long SRA reads, 7 Proteins, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 13 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:131873"
                     /db_xref="HGNC:HGNC:27023"
                     /db_xref="MIM:616613"
     CDS             462..7253
                     /gene="COL6A6"
                     /codon_start=1
                     /product="collagen alpha-6(VI) chain isoform X2"
                     /protein_id="XP_047303401.1"
                     /db_xref="GeneID:131873"
                     /db_xref="HGNC:HGNC:27023"
                     /db_xref="MIM:616613"
                     /translation="MMLLILFLVIICSHISVNQDSGPEYADVVFLVDSSDRLGSKSFP
                     FVKMFITKMISSLPIEADKYRVALAQYSDKLHSEFHLSTFKGRSPMLNHLRKNFGFIG
                     GSLQIGKALQEAHRTYFSAPANGRDKKQFPPILVVLASSESEDNVEEASKALRKDGVK
                     IISVGVQKASEENLKAMATSQFHFNLRTVRDLSMFSQNMTHIIKDVIKYKEGAVDDIF
                     VEACQGPSMADVVFLLDMSINGSEENFDYLKGFLEESVSALDIKENCMRVGLVAYSNE
                     TKVINSLSMGINKSEVLQHIQNLSPRTGKAYTGAAIKKLRKEVFSARNGSRKNQGVPQ
                     IAVLVTHRDSEDNVTKAAVNLRREGVTIFTLGIEGASDTQLEKIASHPAEQYVSKLKT
                     FADLAAHNQTFLKKLRNQITHTVSVFSERTETLKSGCVDTEEADIYLLIDGSGSTQAT
                     DFHEMKTFLSEVVGMFNIAPHKVRVGAVQYADSWDLEFEINKYSNKQDLGKAIENIRQ
                     MGGNTNTGAALNFTLSLLQKAKKQRGNKVPCHLVVLTNGMSKDSILEPANRLREEHIR
                     VYAIGIKEANQTQLREIAGEEKRVYYVHDFDALKDIRNQVVQEICTEEACKEMKADIM
                     FLVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDRVQIGVVQFSDINKEEFQLNRFMSQ
                     SDISNAIDQMAHIGQTTLTGSALSFVSQYFSPTKGARPNIRKFLILITDGEAQDIVKE
                     PAVVLRQEGVIIYSVGVFGSNVTQLEEISGRPEMVFYVENFDILQRIEDDLVFGICSP
                     REECKRIEVLDVVFVIDSSGSIDYDEYNIMKDFMIGLVKKADVGKNQVRFGALKYADD
                     PEVLFYLDDFGTKLEVISVLQNDQAMGGSTYTAEALGFSDHMFTEARGSRLNKGVPQV
                     LIVITDGESHDADKLNATAKALRDKGILVLAVGIDGANPVELLAMAGSSDKYFFVETF
                     GGLKGIFSDVTASVCNSSKVDCEIDKVDLVFLMDGSTSIQPNDFKKMKEFLASVVQDF
                     DVSLNRVRIGAAQFSDTYHPEFPLGTFIGEKEISFQIENIKQIFGNTHIGAALREVEH
                     YFRPDMGSRINTGTPQVLLVLTDGQSQDEVAQAAEALRHRGIDIYSVGIGDVDDQQLI
                     QITGTAEKKLTVHNFDELKKVNKRIVRNICTTAGESNCFVDVVVGFDVSTQEKGQTLL
                     EGQPWMETYLQDILRAISSLNGVSCEVGTETQVSVAFQVTNAMEKYSPKFEIYSENIL
                     NSLKDITVKGPSLLNANLLDSLWDTFQNKSAARGKVVLLFSDGLDDDVEKLEQKSDEL
                     RKEGLNALITVALDGPADSSDLADLPYIEFGKGFEYRTQLSIGMRELGSRLSKQLVNV
                     AERTCCCLFCKCIGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQ
                     GTKGCYGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPG
                     KRGTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTA
                     AHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGP
                     GGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEG
                     FPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGL
                     ASFSTCELIQYVRDRSPGRHGKPECPVHPTELVFALDHSRDVTEQEFERMKEMMAFLV
                     RDIKVRENSCPVGAHIAILSYNSHARHLVRFSDAYKKSQLLREIETIPYERSSASREI
                     GRAMRFISRNVFKRTLPGAHTRKIATFFSSGQSADAHSITTAAMEFGALEIIPVVITF
                     SNVPSVRRAFAIDDTGTFQVIVVPSGADYIPALERLQRCTFCYDVCKPDASCDQARPP
                     PVQSYMDAAFLLDASRNMGSAEFEDIRAFLGALLDHFEITPEPETSVTGDRVALLSHA
                     PPDFLPNTQKSPVRAEFNLTTYRSKRLMKRHVHESVKQLNGDAFIGHALQWTLDNVFL
                     STPNLRRNKVIFVISAGETSHLDGEILKKESLRAKCQGYALFVFSLGPIWDDKELEDL
                     ASHPLDHHLVQLGRIHKPDHSYGVKFVKSFINSIRRAINKYPPINLKIKCNRLNSIDP
                     KQPPRPFRSFVPGPLKATLKEDVLQKAKFFQDKKYLSRVARSGRDDAIQNFMRSTSHT
                     FKNGRMIESAPKQHD"
ORIGIN      
        1 tagttggatg ggagggaccg gccagaatag aggaggctgc atgagaaaga ctgcggtgga
       61 gggaaataag tgaatttcag aagctcaaaa actcctcctt tggcttttct cctcctccaa
      121 acaagagtaa ctgccctcac ctcgtctttc ttttaatttt tcgcatccga ctgttgaaga
      181 acctacagca cactcttgtc attctctgct cccatctccg cgtctcccac cgcgcaccag
      241 ggcgcctcct gagaggtgcg tcacccaaca ctgtgtcctc acagcacagg gcctggcgag
      301 tggcatgtac agtggaccac tctcggaaac aaatgaatgg agttaatcag ggtctgggga
      361 caagaaaaac tcttacgact ttgtaaatat tgatggattg ttttctctaa ggcatttcac
      421 atattagaag atttgaagtt gaagattttt caggtcataa tatgatgttg ctaattttgt
      481 tcctcgtgat aatttgttcc catatttctg tgaaccaaga ttccggccct gagtatgcag
      541 atgttgtgtt tttggtggac agctctgatc gcctgggatc caagtccttc ccatttgtga
      601 aaatgttcat caccaaaatg atcagcagtc tccccataga ggccgacaaa taccgtgtgg
      661 ccctggccca gtacagtgat aaacttcaca gtgaattcca cctgagcacc ttcaaaggca
      721 ggagccccat gctgaaccac ctaaggaaga actttggatt cattggcggg tccctgcaga
      781 taggaaaggc tcttcaggag gctcacagga cttatttctc tgcacccgca aatgggagag
      841 acaagaaaca gtttccccca attctagtgg tcctggcttc atctgagtct gaggataatg
      901 tggaagaggc atcaaaggcc ctgcggaaag acggagtgaa aatcatctct gtaggggtgc
      961 agaaagcttc tgaggaaaac ctgaaggcca tggccacgtc tcagtttcat ttcaaccttc
     1021 ggacagtcag agacctcagc atgttttccc aaaacatgac acacatcatc aaggatgtaa
     1081 taaagtacaa ggagggagca gttgatgaca tctttgtaga agcttgccaa ggcccttcta
     1141 tggccgatgt tgtgttccta ttggatatgt caatcaatgg aagtgaggag aactttgact
     1201 atcttaaagg attcttggaa gaaagtgtat ctgcccttga cataaaggaa aattgcatga
     1261 gggttggcct tgtggcctat agcaatgaga caaaagtgat aaattcactg agcatgggca
     1321 taaataagtc agaggttctc cagcatatac agaacctttc tccccgaact gggaaggcct
     1381 atactggagc tgccatcaaa aagctcagga aggaagtttt tagtgcacgg aatggcagtc
     1441 ggaagaatca gggggtgccc cagattgccg tgctggtgac ccaccgagat tcagaagaca
     1501 acgtgacaaa agcagctgtt aacctccgac gggagggtgt gaccatcttc accctgggca
     1561 tagagggcgc cagcgacacc cagttggaaa agatagcatc ccaccctgct gagcagtatg
     1621 tctccaaact gaagaccttc gctgacctgg ctgctcacaa ccagacattt ctgaagaagc
     1681 tgcggaacca aataacacac acagtctctg tcttttcaga gaggactgaa acgctcaaat
     1741 ctggttgtgt ggacactgag gaagcagaca tctatctgct tatcgatggc tcagggagca
     1801 cccaggccac agatttccat gaaatgaaga cgttcctgtc agaggtggta gggatgttca
     1861 acattgctcc ccataaggtg cgggttgggg ccgttcagta tgctgacagc tgggacttgg
     1921 aatttgagat caataaatac tccaacaagc aggatttggg aaaggccatt gagaatatca
     1981 ggcagatggg tgggaataca aacacaggcg cagcactgaa tttcacactg agtctgttgc
     2041 aaaaagcaaa gaagcagcga ggaaacaaag ttccatgcca ccttgttgtc ctgacaaatg
     2101 gcatgtccaa ggatagcatc ttggagcctg caaacagact gagagaagag cacatccgag
     2161 tttatgctat cgggatcaag gaggccaacc aaacacagct gagagaaatt gcaggagagg
     2221 aaaagagagt gtattacgtg catgactttg atgcattgaa agacataaga aaccaagttg
     2281 ttcaagaaat ctgtactgaa gaagcttgca aagagatgaa agctgacatc atgtttctgg
     2341 tggacagttc tggaagtata ggacctgaaa acttcagcaa aatgaaaaca tttatgaaaa
     2401 acctggtgag caagtctcag attggaccag atcgggtgca aattggtgta gtccagttca
     2461 gcgacatcaa taaggaagag tttcagctca acagattcat gtcccaaagc gacatttcaa
     2521 atgcaataga ccaaatggct cacattggac aaaccaccct gactggtagt gccctgagct
     2581 ttgtgtctca gtacttcagc cccaccaagg gcgcccggcc caacatcaga aagtttctca
     2641 tcctcatcac ggatggtgaa gctcaggaca tagtaaagga accagcagta gtgcttcggc
     2701 aagaaggtgt aatcatctat tctgtgggag tgtttggctc caatgtcacc cagcttgagg
     2761 agatcagtgg gaggcccgag atggtttttt atgttgagaa ttttgacatt ctgcagcgca
     2821 ttgaagatga tcttgttttt ggaatatgca gcccccgtga agaatgcaag cggattgaag
     2881 ttttagacgt tgtgtttgtc attgatagct ctggcagtat tgactatgat gagtataata
     2941 tcatgaagga ttttatgatt ggcttagtga aaaaagctga tgtgggcaag aatcaggtcc
     3001 ggtttggggc tctgaagtat gctgatgacc cagaggtgct gttttatctg gatgactttg
     3061 gcacaaaact ggaggtaatt tcagtgctcc agaatgacca agccatgggt ggcagtactt
     3121 atactgctga ggcactgggc ttctcagacc acatgttcac tgaagcccgg ggcagccgcc
     3181 tgaacaaggg ggtcccccaa gtcctcattg tgatcaccga tggggaatcc catgatgctg
     3241 ataaactcaa tgccacggca aaggccttgc gggacaaagg cattcttgtc ctggctgtgg
     3301 ggattgatgg tgccaatccc gtggagctgt tagccatggc aggatcaagc gacaagtact
     3361 tcttcgtgga gacttttgga ggtctgaagg gaatattttc agatgtgaca gccagtgtct
     3421 gcaactcttc aaaagtagat tgtgaaattg acaaagtaga tcttgttttc cttatggatg
     3481 gttcaactag cattcagcca aatgacttca agaaaatgaa ggaatttctg gcatctgttg
     3541 ttcaagactt tgatgtcagc ctcaacagag tgcgaatagg agcggcccag tttagcgata
     3601 cctatcaccc ggagtttcca ctgggaactt tcataggtga aaaagagata tcatttcaga
     3661 ttgaaaacat caagcagatc tttggaaaca cacacatcgg tgctgcactc agggaggtgg
     3721 aacattactt caggccagac atgggcagca ggataaatac aggtacccca caggtgctgc
     3781 tggtccttac agatggccag tcccaagacg aggtggccca ggccgcggaa gccctgagac
     3841 acagaggtat cgacatctac tccgtgggca ttggggatgt ggatgaccag cagctcattc
     3901 agatcaccgg gactgcagag aaaaaactga cagtgcacaa cttcgatgaa ctgaagaagg
     3961 tcaataaaag gatcgttcgc aacatctgta ccacagcggg tgaaagcaac tgtttcgtgg
     4021 atgttgtggt gggatttgat gtctcaactc aggagaaagg gcagactttg cttgaaggtc
     4081 agccttggat ggaaacctac cttcaagaca tcttacgtgc catcagctcc ctcaatggag
     4141 taagctgtga ggtgggcaca gagactcagg tcagtgtggc ttttcaagtg accaatgcca
     4201 tggaaaaata ttctcccaag tttgagatct acagtgaaaa catactgaat agcttgaagg
     4261 atataacagt taaaggacca tctcttctca atgcaaacct cttggattct ctatgggata
     4321 catttcagaa taaatcagct gctcgaggaa aggtggtcct tttattttca gatggattgg
     4381 atgatgatgt tgagaaactt gaacaaaaat ctgatgaact tagaaaagaa ggcctgaatg
     4441 ccctcataac tgttgctctg gatggacctg ctgattcaag tgacttggct gatcttccct
     4501 atattgaatt tgggaaagga tttgagtaca ggacacagct ctctattggc atgagagaac
     4561 ttggaagccg gctgtcaaag cagctggtca atgttgctga aaggacatgc tgctgtttgt
     4621 tctgcaagtg cattggagga gatggcacaa tgggagatcc tggaccacca gggaaaaggg
     4681 gacctccagg ttttaaaggc agtgaaggct acctgggaga ggagggaatc gctggagaaa
     4741 gaggagcccc tggaccagtg ggagagcaag gtactaaggg atgctatggc accaaaggtc
     4801 ctaagggaaa cagaggacta aatggacagg agggagaagt tggggaaaat ggaattgacg
     4861 gattaaacgg agaacagggt gataatggtc ttcctggaag aaaaggagaa aagggagatg
     4921 agggatctca gggaagccca gggaagagag ggactcctgg tgaccgtgga gcaaagggcc
     4981 tgcgagggga tcccggagct cctggagttg acagtagcat agaaggaccc acaggcttga
     5041 aaggagaacg tggaagacaa ggcagaagag gctggccagg cccccccggg acaccaggct
     5101 ccagaagaaa gacagcagct catggcagaa ggggacatac aggcccacag ggaacagcag
     5161 gcatcccagg accagatgga cttgaaggct ccctgggact taagggccct cagggcccaa
     5221 gaggagaggc tggtgtgaaa ggagaaaaag gaggtgtggg aagtaaaggt ccccaggggc
     5281 ctccaggacc cggaggagag gcagggaatc aaggccgttt gggaagccaa ggaaataaag
     5341 gagaacctgg agatctggga gaaaaaggag ctgttggctt tcctggtcct cgtggcttgc
     5401 agggcaatga tggcagtcca ggttatggta gtgtcggacg caagggagca aagggacaag
     5461 aaggattccc tggagaaagt ggacctaagg gtgagattgg ggaccctggt ggtccaggag
     5521 agactgggct gaagggagct agaggcaaaa tgatatctgc tgggcttcca ggagagatgg
     5581 gatcccctgg ggaaccagga cctcctggac gtaagggtgt gaaaggagcc aaaggcttgg
     5641 cttcattttc tacatgtgag ctcattcagt atgtgcgaga ccgcagtcct ggcaggcatg
     5701 gaaaaccgga atgcccagtg cacccaaccg agttggtgtt tgccctggac cactcccggg
     5761 atgtcactga gcaggaattt gagcggatga aggagatgat ggctttcctg gtgagagaca
     5821 ttaaggtccg ggagaacagc tgccccgtgg gagcgcacat cgccatcctc tcctataact
     5881 cccacgccag gcaccttgtg cgcttctcag acgcctacaa gaagagtcaa cttctcagag
     5941 aaattgaaac tattccttat gagagatcct ctgccagcag ggagattggc agagcaatgc
     6001 ggtttatttc caggaatgtc ttcaagcgga cgcttccggg ggcacacacg agaaaaatcg
     6061 ccacattttt cagcagcggt cagtccgcgg atgcccactc catcaccacg gctgccatgg
     6121 agttcggcgc gcttgaaatc attcccgtgg tgatcacttt cagcaacgtg ccctcggtca
     6181 ggcgcgcatt tgcgattgac gacactggca catttcaagt aatagtggtt ccctccgggg
     6241 ccgactacat accagcatta gagagactcc agcggtgcac tttctgctat gatgtgtgca
     6301 agccagatgc ttcttgtgac caagccagac caccccctgt gcagtcttac atggatgctg
     6361 ctttccttct ggatgcctcc cggaacatgg gaagtgctga atttgaagac ataagagcct
     6421 tccttggagc actattagat cactttgaaa tcaccccaga gccggagact tctgtcactg
     6481 gagaccgggt ggccctattg agccatgctc cccccgactt cctacccaac actcagaaga
     6541 gtccagttag agctgagttc aatcttacca cctacagaag taagcgcctc atgaagaggc
     6601 atgtgcacga gtcagttaaa caactaaatg gagatgcttt tattggtcat gccttacagt
     6661 ggactctgga caatgtattt ttaagtacac ccaatctgag aagaaacaaa gtcatatttg
     6721 tgatatctgc tggggaaacc agccacttag atggggaaat cttaaagaag gaatccttgc
     6781 gagccaaatg tcagggatat gccttatttg tgttttccct tggccctatt tgggatgaca
     6841 aggaactgga ggatctcgcc agccaccctt tggatcacca cctggtccag cttggccgaa
     6901 ttcataaacc tgaccacagt tatggtgtga agtttgtgaa gtcctttata aactcaatca
     6961 ggcgtgcaat caacaaatat ccaccaataa acttaaaaat aaagtgcaac agacttaact
     7021 ctatagatcc aaagcagccc ccacgaccat tccgaagctt tgttcctgga ccacttaaag
     7081 ctaccctcaa agaagatgta ttacagaagg caaaattctt tcaagataaa aaatatcttt
     7141 caagagtagc aagaagtggc agagatgatg ctattcaaaa ttttatgaga agcacctccc
     7201 atacctttaa gaatggaagg atgatagaaa gtgctcccaa acaacatgat taaaaaaatg
     7261 cttgaacaac ttagccttag gaagcatggt aagactctgg acttaaatag taactaaatc
     7321 tgctgccaga actcaagcaa cagtttgtag gttatcaggt gacttgaccc cctgcattca
     7381 ttggtattaa gatatatctt gttcatttat ttgaccactc ctgacaattc cagcactcta
     7441 cgactgatat gtcgaagaac tgtttcatta gaagacagaa gaatgaaaga agtgttttga
     7501 aaagtctaat ggagatataa tttgaaggta aaatttatat gatgtatgca tatgtgtaca
     7561 tgggtcaatg ttaattcttt tatctctgtc cagttcattt tctgcaaacc catcctcctt
     7621 tcctaattta gtaatgtcta atgctcatct atttagtcaa agttattttt taatgtttta
     7681 agctactcca aaatttatcc tagaaatgga tgctgtttat atgtcgtatt tttttaaaac
     7741 gtgaccttct attccactta aacacaccac tgtgggagtt gtttgcttgg actgatgaga
     7801 agagggtaat tttctccatc tctaaatcct cctgaactca ctgaaaaact cattaattcc
     7861 cgcagaacat aaattattgc ttttgagctg gaagttttct cttcattagg aagcttactg
     7921 ccattttgat ggagcttgaa gcccccattt tgatggactt ctagtctgtc tttcctgtta
     7981 tggtcattta ttaattttca ctaatccata tattctttag acaaggagag tcaagaaact
     8041 acttgtcata gatgaagctc tgagttactt ttacccatca ggtagctgtt tagtcaataa
     8101 taaacagcac caaaacagga ttagcagagc tcttaaaaac agccttaaat acacactgag
     8161 tttagaaaaa tgtaagaaaa tcattgtttt aatctacaaa ttcatatgca gttgcagaga
     8221 tgcaaaagag atcagagtaa gttaaagtag gaaaggtttt ataaaagtat tgatggctgt
     8281 gtcctcatct gcatttttgt ttttatgata gggctgatat tttcaacaac gaaacaccca
     8341 atgttcagac cttacctcag tctaagagct ggctccacag ttggtagcaa tggccctgtt
     8401 aggcagactg tccccctctt tgggaatgga aagaagccct gcctggatgc atggagcaga
     8461 tggatactga caccaaggac attcagattt tctttcctat acctattttc ataaaatttg
     8521 gaaagaaaaa ctatctgcag tattttttta aaacgacttc tgctattctt acttagagaa
     8581 atccagtgat agcacctcat gtcttcagag gagcaagaag ttcaaggagt taaatgtcac
     8641 attcatactc aggtaataga gaagaataaa acacatcagg tttgcttcat ctatcctaag
     8701 tggtgcttag gggttcagaa aaaatgtttc aagtacagga aattaatgag caatatttac
     8761 aatgtatttt aataaaaggg atttttctag ttaactctga gttaagcacg aactcctttc
     8821 ttttgttaat tgttggaaat accattaaga tgtatttgtc tgtttttctg cattggcaag
     8881 taaagaacat aaaacaaa
//
