LOCUS       XM_011532356            7026 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens collagen type XXV alpha 1 chain (COL25A1),
            transcript variant X6, mRNA.
ACCESSION   XM_011532356
VERSION     XM_011532356.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000004.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011532356.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7026
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
     gene            1..7026
                     /gene="COL25A1"
                     /gene_synonym="AMY; CFEOM5; CLAC; CLAC-P; CLACP"
                     /note="collagen type XXV alpha 1 chain; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 1 mRNA, 3 ESTs, 131 long SRA reads, and 100% coverage
                     of the annotated genomic feature by RNAseq alignments,
                     including 3 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:84570"
                     /db_xref="HGNC:HGNC:18603"
                     /db_xref="MIM:610004"
     CDS             91..1824
                     /gene="COL25A1"
                     /gene_synonym="AMY; CFEOM5; CLAC; CLAC-P; CLACP"
                     /codon_start=1
                     /product="collagen alpha-1(XXV) chain isoform X3"
                     /protein_id="XP_011530658.1"
                     /db_xref="GeneID:84570"
                     /db_xref="HGNC:HGNC:18603"
                     /db_xref="MIM:610004"
                     /translation="MGCPLMTMPGPPGKRGKRGRRGESGPPGPPGPKGDKGEQGDQGP
                     RMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMP
                     GVPGEPGKPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKG
                     EPGEQGEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLP
                     GIKGEPGFIGPQGEPGLPGLPGTKGERGEAGPPGRGERGEPGAPGPKGKQGESGTRGP
                     KGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGP
                     PGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMK
                     GEKGDSGMPGPQGPSIIGPPGPPGPHGPPGPMGPHGLPGPKGEPGLNGVKGLKGEPGQ
                     KGDRGPLGLPGASGLDGKPGSRGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLP
                     GKDGEPGLDGFPGPRGEKGDLGEKGEKGEKGKKGKKGPKGEKGEQGAPGLDAPCPLGP
                     DGLPMPGCWQK"
ORIGIN      
        1 gtcaggtcag ctgaacactt agctgatagc tagcattagc tgctggccag gtgcataagc
       61 catcttagat gtccagccca ggttcataga atgggatgcc cactgatgac aatgccaggc
      121 cctccaggga aacgaggtaa gagaggccga agaggagaat ctggtcctcc tggccctcct
      181 ggtccaaaag gcgataaggg agaacaaggt gatcagggac ctaggatggt gtttcctaaa
      241 atcaatcatg ggtttctctc tgctgatcag cagctcatta aacgccgcct gattaagggt
      301 gaccaaggac aggcagggcc tccaggaccc cctggccctc caggcccaag agggccacct
      361 ggggacacag ggaaagatgg cccccgtgga atgccaggag tacccggtga accaggaaag
      421 ccaggagaac aaggcttgat gggtcctcta gggcctccgg gacaaaaggg ttctattgga
      481 gcacctggaa ttccagggat gaatgggcaa aagggtgagc ccgggttgcc tggagcagta
      541 ggacagaatg gaataccagg acctaaggga gaacctggag aacaaggtga aaagggagac
      601 gctggagaga acggccccaa gggtgacaca ggcgaaaagg gtgaccctgg atcatctgct
      661 gcaggaatta agggagaacc tggggaatct ggtcgtccag ggcaaaaggg tgaaccaggg
      721 cttcctgggc ttcctggact tccggggata aagggagaac caggtttcat tggtcctcaa
      781 ggagaaccag gcttaccagg tttaccagga acaaaaggtg aacgggggga agcagggcct
      841 cctggaagag gtgagcgagg ggaacctgga gcccccggac caaaggggaa acaaggtgaa
      901 tcaggaacta gaggcccaaa ggggtcaaag ggggatcgtg gagaaaaagg ggactctgga
      961 gctcagggac caaggggtcc acctggtcaa aaaggggatc aaggagccac tgagatcata
     1021 gactacaacg gcaacctcca cgaagcctta cagaggatta ccaccttaac tgtcacgggt
     1081 ccccctggac ctcctggacc tcaaggacta caagggccaa agggagagca gggatctcca
     1141 ggaatcccag gaatggatgg agagcaggga ctcaaaggct caaagggaga catgggggac
     1201 ccaggtatga caggtgaaaa aggaggaatt ggacttcctg gattaccggg agccaatgga
     1261 atgaaaggag aaaaaggaga ttctggaatg ccgggtccac agggtccttc tatcataggc
     1321 ccaccaggcc caccaggtcc ccatggccca cctggcccca tgggacctca tggacttcct
     1381 ggaccaaagg gtgaaccagg gttaaatggt gttaaaggat tgaagggtga accaggtcaa
     1441 aagggtgaca gaggacccct tggtcttcca ggagcatctg gcttagacgg aaagccagga
     1501 tcccggggta cagatggtcc tatgggaccc catggccctg caggtcccaa aggagaaaga
     1561 ggtgaaaaag gagctatggg agagcctgga ccaagagggc cctatgggct gcctgggaaa
     1621 gatggagagc ctggtcttga tggcttccct ggtccacggg gtgagaaggg tgatctagga
     1681 gaaaagggag aaaaggggga aaagggaaag aaaggcaaaa aggggcctaa aggggagaaa
     1741 ggagaacagg gtgctcctgg attagatgca ccctgcccgt tggggccaga tggcttaccc
     1801 atgcctggct gttggcaaaa gtgatgaatc taacctttca agcatgaagt tgtgtatata
     1861 agggtccatt tttaatattt atagttgaaa actgaattgc agattttaca agtctgagat
     1921 atgtttacat agggctgctt cttcctgctg gcagtagtat acatgtccat ttttactcca
     1981 cttacatctg aaattgggca atttgtgaaa ccagtgagaa tcctgcaaaa aatatagatc
     2041 agtatctcct tatcttatgt gaagatacgt atttatatgg acaaatcagt ggtagagaat
     2101 gattgattgt actagctatt ttccttcttt tggcttgcta attgcatgga caaaaagtgc
     2161 catgaaatag tttacatgaa atggtgacca aatatggact caaagctatg aaaatgtact
     2221 atactgactg attttagagc tgattatcac attcccattc acctttcatg tcggcgttga
     2281 ctcataccta caccacccat tgaaactaac taaaaaagca tgactgtgtg ccaaacctgc
     2341 ttgctgtgca acttcagatg ctagcatgtt gatcaggagt cctttgatta catctgaacc
     2401 tttattcctt ttgtcatctc aagggggtta caccatggct tattgccaaa aagagataag
     2461 gtggcggaga gcacacacac aatttgtctt gtattttgag ggagttgcag tcctgactgc
     2521 agatctacag cttccagtat tgtgggctca tgtggccact ttggttgaaa tacgaagggg
     2581 ttgagcctgt tgctgccacc agttttcctt gggctgccct tggcagtgaa gacatgggaa
     2641 gaggaccgat tcagcctcca gcactgcctc tcatgtgacc aagtaggaaa gaggtttaca
     2701 aatgcaaaca tgcagaacca cagactttaa aaatatgtat aaataaactg aatttcagca
     2761 agtgttaata taggtgcttt taaaaatgac agaggcacag cacttctttt ggaataggag
     2821 attcttggaa tgggagatcc tgtccctgag ggaaaaggga tgtccatccc accaaaactt
     2881 gggttgctga agaaataaca tgttctgaga agggatcagc caaaatcgcc tctcccgatg
     2941 atataggaga gcttactggg acaatctgtg ccaaagttgt tgtgagagct ttccttcctc
     3001 ctacgatcca accatgtcaa acatttccta caaagtttga gaaacaggta tttttcattc
     3061 tttttaatgc ttttttcttt ttctttcttt agtcccaaga atattgaaaa aatattagtt
     3121 tcagtttttg tcacatatgt tttgaacaat ttttttaaga agtcttcaaa tcataataat
     3181 ttggctccag tagtcaaaat gaccttttac taacttctct cttgttttgg ataattggat
     3241 agaatataaa agaagctcca ctttcagtct aatcattgta aagcatgaaa gttatgcatt
     3301 tttaagtagt tttgactttt tttacatgat gaatgtaacg tacatggaga ttatcagtta
     3361 atataaagcc aagattttgt cacatttggt aatattaact aatttctatt tttatggttt
     3421 taagttttgt ctatatttag atttctttct ctttttaaca tttctaaatg tttgtctcat
     3481 cctcatatcc acagaccaaa tctaagatct cagaaagctg tgaaatatag ttgccataaa
     3541 gaaaatattt ttcatctact tgctcaaact ttacctaacc atattagatg gaacatttct
     3601 ttgcacagta aagagttggt agcgtgtttt gaaatggctt attctaagtg gaagtgttac
     3661 attgaaagaa acattatcaa tgaggagtag gcaccctttc agcccattag agaatttaat
     3721 ttctctcctg actcaatgcc atcttctggg aagatttcta gtttcatgca taggtgtcac
     3781 caccagaagg gaaattaact catccttggc ttatagttaa gatataacca taagacaagg
     3841 aacctaaaat cctcatgatc tcatttatgt tatgtaacca aatgacagtc atacaaaatg
     3901 gcatcttctt ttttttctat taaattttta aggttgaaag atgtttaaac tattagatca
     3961 gtctaattgg taacatttct ggtaacattc cacaccccta agccagttta gcattttgaa
     4021 aataatggag gacattttct aacaatttct tgtatggcat ggtgttagga taacgtattg
     4081 ctcaatgtct gacacaattt gtcttaaatg gtttggaaaa atgaactgaa gtgggtggaa
     4141 ctacattctc ttcaggaaaa caaactacag tgtccagtgg ctatattttt ttcccttcta
     4201 tctttttttc tgctcctcta gtagaaagag gtggattgaa atggatcact atttaaaact
     4261 tgcacagctt caggagacga tacctcaaca tcaaaagaaa aacactttat gtataaaaaa
     4321 attttttgaa atacagccct tcaaagaata ctattctgtc ctgtgtgtat attgagtttt
     4381 tgctctataa ctgatttgac aacatcaact tatttcatga ttaaatgagg ttgtaaactt
     4441 tcattacatt tatttccttg ggaaaaacaa agggatggaa atactcctcc ttgttcagtg
     4501 gaattgctag gtcttaacca tgatggataa tctttaactt ttggttacta caatgttttc
     4561 aagcatccat tttgtcatat agagaattct taaataattt ctaagtgaat gaaagaattg
     4621 tgtttgttga tatgtgttga tagataatat actttcctta aagatttctt taatgtgtgt
     4681 tattggatag agggttgaga aaatatacat gaaagacaca ttggaaataa ggcaaggtca
     4741 gtttctattt ctaataaaac attgaaggat agcaaattga tatgtgtttt agatttaaaa
     4801 ttgtttttca tttatgttgg ttggtgctaa tgtatctctt ttcctttttc tctatggaca
     4861 atacaactac tatggataat tttatttccc tgtttaatag cattcctaaa tcattagtgt
     4921 gttattttat ttttaaagtt catgaatttg ctataattat ggtccaatga ccaggctttc
     4981 ttaatgtaaa acaaaacagt gtaccaatag atgatgtgtg tttactcgga tcatggatcc
     5041 tcctatttca tattcatttc atacatcata tgcctttatc tactttcatg tgtctcatct
     5101 ttttcattca ctcgtctttt agtttatatg atttgatgaa acatgacaaa actagcatca
     5161 gagaagtctg cacacaccgt atagagtacc tagtgcacaa atatacctaa ttttttcttt
     5221 cagtttttgt ttttcattag caaaagcagt cttggaggat ttttttttct catgtgattt
     5281 tatagaggac attagaatat ctttaattcc taccagaaga aaggtcttgt ttttgaattt
     5341 acattctgtg catacgatgt tctgatggga cagcaagaac ttacacatca actagtttat
     5401 actacatgtc ctttgtctaa ctatctatct atatagacat atgtgctagt ttagaaaatt
     5461 gtcaaatcag catgtcagta ccaatggaaa aattgtcttt gatatgttat atttttctca
     5521 cttaggaaat gtgcttaatt tccaagggtt ttttttttta atgttactat tgaagcatga
     5581 aaagttaaca tcatttgtta tcctttcttt ccccactata tattgtctta cccagagtag
     5641 ggctatactt tggtggtgtt ttaacatctt ctaataagtg atcataagca acatacagat
     5701 gctaatattt gaaatcttgt tttttcttac ttcctaataa tcaaattata ttaatatttc
     5761 acactacaaa aaaataggat tttctaattt gtaaaaacaa gagctcctgc tatctcttgg
     5821 aagttaagtc cttaggaacc ctatcttatc tttctaaaaa taataagtaa gaacaatcac
     5881 atgtgattct ggctattaaa atcatacatc cctagtggaa ttaacaagct tgaccaatta
     5941 tgattatgct aaattgtttt aggctaggag gactgtcagt ccctacttct tcccattttt
     6001 cttgggatat ctttatattg gctagatttg ttgccaatat aaaattgaca cagcagagac
     6061 actcctctaa cttaaatttt tagtggagtt tggtttttgc taaccccgta ctaataaaca
     6121 ctttaatgac ttttttcatt tcaaaatatt taaatgtata aaattgccta tgctgcttat
     6181 tgaaagaacc gtccttttgg gcataagaag actttttcaa cctaaaccgt tatgtgtgat
     6241 ttattaacaa cttaacaaag aaagtaccaa catctctcaa aatgtagttg atattcttac
     6301 ctatctcaga aatattaacg aattggattc acaaaagaat gtcttacata ctgttgacat
     6361 ttatgtgaat attctttata ctgttgtaaa tgtttcattc aacttaataa cattttaaaa
     6421 gatgtatgta tctgattttt ctttagaaaa tattatattt ttatttgtat tttttacatt
     6481 ttaaagttca tctctatgtg cagctatttt tatattgcca aaaactcaca taaatacaaa
     6541 ataagtgaaa tatgcaaaaa aaaatatttt ggcaagcatt acactgcata tttttttaaa
     6601 tgtttgtggg ccagtctcat acaattgatt attctaagaa tgtgttgtgt cttatcactg
     6661 taaatatggc acaaacctgt ttatctcagt agtgtaaata attgaaagat tgaattctcc
     6721 ctgttcaatt tttattttaa tttccttgta atttctccag ctgacattac tgtatcaaaa
     6781 gatgcataag atttttgatt tgcggtttgg agataattgc attgtgttca gtttccagtt
     6841 tgtttttatt tgctttttaa atttgttttc agggttccta gtttgtgaga agttgatctt
     6901 cagaattatt tttacactat ttatgactta ttttcataat gtaaaaagtg tgtaattatt
     6961 acaatattaa tccaaacaat gataatgaat tgtattgtta taaagcttta ttgatgttca
     7021 tgaaaa
//
