LOCUS       NM_004370              11725 bp    mRNA    linear   PRI 11-FEB-2025
DEFINITION  Homo sapiens collagen type XII alpha 1 chain (COL12A1), transcript
            variant long, mRNA.
ACCESSION   NM_004370
VERSION     NM_004370.6
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 11725)
  AUTHORS   Naghipoor,K., Khosravi,T. and Oladnabi,M.
  TITLE     Whole exome sequencing identifies a novel variant in the COL12A1
            gene in a family with Ullrich congenital muscular dystrophy 2
  JOURNAL   Mol Biol Rep 50 (9), 7427-7435 (2023)
   PUBMED   37458870
  REMARK    GeneRIF: Whole exome sequencing identifies a novel variant in the
            COL12A1 gene in a family with Ullrich congenital muscular dystrophy
            2.
REFERENCE   2  (bases 1 to 11725)
  AUTHORS   Yao,W., Yao,Y., He,W., Zhao,C., Liu,D., Wang,G. and Wang,Z.
  TITLE     PABPC1 promotes cell proliferation and metastasis in pancreatic
            adenocarcinoma by regulating COL12A1 expression
  JOURNAL   Immun Inflamm Dis 11 (7), e919 (2023)
   PUBMED   37506150
  REMARK    GeneRIF: PABPC1 promotes cell proliferation and metastasis in
            pancreatic adenocarcinoma by regulating COL12A1 expression.
REFERENCE   3  (bases 1 to 11725)
  AUTHORS   Tang,Z., Yang,Y., Zhang,Q. and Liang,T.
  TITLE     Epigenetic dysregulation-mediated COL12A1 upregulation predicts
            worse outcome in intrahepatic cholangiocarcinoma patients
  JOURNAL   Clin Epigenetics 15 (1), 13 (2023)
   PUBMED   36694230
  REMARK    GeneRIF: Epigenetic dysregulation-mediated COL12A1 upregulation
            predicts worse outcome in intrahepatic cholangiocarcinoma patients.
            Erratum:[Clin Epigenetics. 2023 Mar 21;15(1):46. doi:
            10.1186/s13148-023-01455-3.. PMID: 36945022]
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 11725)
  AUTHORS   Papanicolaou,M., Parker,A.L., Yam,M., Filipe,E.C., Wu,S.Z.,
            Chitty,J.L., Wyllie,K., Tran,E., Mok,E., Nadalini,A., Skhinas,J.N.,
            Lucas,M.C., Herrmann,D., Nobis,M., Pereira,B.A., Law,A.M.K.,
            Castillo,L., Murphy,K.J., Zaratzian,A., Hastings,J.F.,
            Croucher,D.R., Lim,E., Oliver,B.G., Mora,F.V., Parker,B.L.,
            Gallego-Ortega,D., Swarbrick,A., O'Toole,S., Timpson,P. and
            Cox,T.R.
  TITLE     Temporal profiling of the breast tumour microenvironment reveals
            collagen XII as a driver of metastasis
  JOURNAL   Nat Commun 13 (1), 4587 (2022)
   PUBMED   35933466
  REMARK    GeneRIF: Temporal profiling of the breast tumour microenvironment
            reveals collagen XII as a driver of metastasis.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 11725)
  AUTHORS   Li,Y., Su,Z., Wei,B., Qin,M. and Liang,Z.
  TITLE     Bioinformatics analysis identified MMP14 and COL12A1 as
            immune-related biomarkers associated with pancreatic adenocarcinoma
            prognosis
  JOURNAL   Math Biosci Eng 18 (5), 5921-5942 (2021)
   PUBMED   34517516
  REMARK    GeneRIF: Bioinformatics analysis identified MMP14 and COL12A1 as
            immune-related biomarkers associated with pancreatic adenocarcinoma
            prognosis.
REFERENCE   6  (bases 1 to 11725)
  AUTHORS   Berthod,F., Germain,L., Guignard,R., Lethias,C., Garrone,R.,
            Damour,O., van der Rest,M. and Auger,F.A.
  TITLE     Differential expression of collagens XII and XIV in human skin and
            in reconstructed skin
  JOURNAL   J Invest Dermatol 108 (5), 737-742 (1997)
   PUBMED   9129225
REFERENCE   7  (bases 1 to 11725)
  AUTHORS   Gerecke,D.R., Olson,P.F., Koch,M., Knoll,J.H., Taylor,R.,
            Hudson,D.L., Champliaud,M.F., Olsen,B.R. and Burgeson,R.E.
  TITLE     Complete primary structure of two splice variants of collagen XII,
            and assignment of alpha 1(XII) collagen (COL12A1), alpha 1(IX)
            collagen (COL9A1), and alpha 1(XIX) collagen (COL19A1) to human
            chromosome 6q12-q13
  JOURNAL   Genomics 41 (2), 236-242 (1997)
   PUBMED   9143499
REFERENCE   8  (bases 1 to 11725)
  AUTHORS   Walchli,C., Koch,M., Chiquet,M., Odermatt,B.F. and Trueb,B.
  TITLE     Tissue-specific expression of the fibril-associated collagens XII
            and XIV
  JOURNAL   J Cell Sci 107 (Pt 2), 669-681 (1994)
   PUBMED   8207089
REFERENCE   9  (bases 1 to 11725)
  AUTHORS   Oh,S.P., Taylor,R.W., Gerecke,D.R., Rochelle,J.M., Seldin,M.F. and
            Olsen,B.R.
  TITLE     The mouse alpha 1(XII) and human alpha 1(XII)-like collagen genes
            are localized on mouse chromosome 9 and human chromosome 6
  JOURNAL   Genomics 14 (2), 225-231 (1992)
   PUBMED   1427837
REFERENCE   10 (bases 1 to 11725)
  AUTHORS   Sugrue,S.P., Gordon,M.K., Seyer,J., Dublet,B., van der Rest,M. and
            Olsen,B.R.
  TITLE     Immunoidentification of type XII collagen in embryonic tissues
  JOURNAL   J Cell Biol 109 (2), 939-945 (1989)
   PUBMED   2668306
  REMARK    Erratum:[J Cell Biol 1989 Nov;109(5):following 2254]
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL080250.11, DA661773.1,
            BP286308.1, AL354664.12, U73778.1, AL096771.11 and AI752603.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 23, 2018 this sequence version replaced NM_004370.5.
            
            Summary: This gene encodes the alpha chain of type XII collagen, a
            member of the FACIT (fibril-associated collagens with interrupted
            triple helices) collagen family. Type XII collagen is a homotrimer
            found in association with type I collagen, an association that is
            thought to modify the interactions between collagen I fibrils and
            the surrounding matrix. Alternatively spliced transcript variants
            encoding different isoforms have been identified. [provided by
            RefSeq, Jul 2008].
            
            Transcript Variant: This variant (long) represents a transcript
            that encodes an isoform longer than that of the short isoform.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U73778.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000322507.13/ ENSP00000325146.8
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-146               AL080250.11        24505-24650         c
            147-573             DA661773.1         145-571
            574-1013            BP286308.1         150-589
            1014-1135           AL080250.11        7814-7935           c
            1136-1309           AL080250.11        6959-7132           c
            1310-1600           AL080250.11        2451-2741           c
            1601-2203           AL080250.11        1647-2249           c
            2204-2476           AL354664.12        9642-9914           c
            2477-2749           AL354664.12        6366-6638           c
            2750-3022           AL354664.12        3741-4013           c
            3023-4375           U73778.1           2824-4176
            4376-4459           AL096771.11        20174-20257
            4460-5380           U73778.1           4261-5181
            5381-5775           AI752603.1         11-405
            5776-5836           AL096771.11        36612-36672
            5837-5976           AL096771.11        37401-37540
            5977-6106           AL096771.11        37976-38105
            6107-6249           AL096771.11        39316-39458
            6250-7040           U73778.1           6051-6841
            7041-7183           AL096771.11        47308-47450
            7184-8853           U73778.1           6985-8654
            8854-8885           AL096771.11        74110-74141
            8886-9314           U73778.1           8687-9115
            9315-9322           AL096771.11        82285-82292
            9323-9493           AL096771.11        83651-83821
            9494-11725          AL096771.11        84841-87072
FEATURES             Location/Qualifiers
     source          1..11725
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6q13-q14.1"
     gene            1..11725
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /note="collagen type XII alpha 1 chain"
                     /db_xref="GeneID:1303"
                     /db_xref="HGNC:HGNC:2188"
                     /db_xref="MIM:120320"
     exon            1..277
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            278..385
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     CDS             313..9504
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /note="long isoform precursor is encoded by transcript
                     variant long; collagen type XII proteoglycan; collagen
                     alpha-1(XII) chain; collagen, type XII, alpha 1"
                     /codon_start=1
                     /product="collagen alpha-1(XII) chain long isoform
                     precursor"
                     /protein_id="NP_004361.3"
                     /db_xref="CCDS:CCDS43482.1"
                     /db_xref="GeneID:1303"
                     /db_xref="HGNC:HGNC:2188"
                     /db_xref="MIM:120320"
                     /translation="MRSRLPPALAALGAALLLSSIEAEVDPPSDLNFKIIDENTVHMS
                     WAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSELVPETEYVVTITSYDEVEE
                     SVPVIGQLTIQTGSSTKPVEKKPGKTEIQKCSVSAWTDLVFLVDGSWSVGRNNFKYIL
                     DFIAALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQYYQRDELLAAIKKIPYKGGNTM
                     TGDAIDYLVKNTFTESAGARVGFPKVAIIITDGKSQDEVEIPARELRNVGVEVFSLGI
                     KAADAKELKQIASTPSLNHVFNVANFDAIVDIQNEIISQVCSGVDEQLGELVSGEEVV
                     EPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQTTTLSVR
                     DLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYS
                     IGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAIN
                     TFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRN
                     SDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQEL
                     AAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVEPAS
                     STSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFK
                     ITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFS
                     GPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGET
                     QEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTK
                     DITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYR
                     ISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVY
                     RPHGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFK
                     SPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEE
                     LRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLV
                     DGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSL
                     LQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPS
                     KKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNS
                     VKGPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRME
                     TSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQW
                     QPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDL
                     TSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEV
                     EVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTS
                     EGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITA
                     IYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYR
                     ITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTK
                     PLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAIL
                     RNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAP
                     GPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPS
                     PAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVP
                     GRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRF
                     RVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDS
                     GLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQEI
                     TVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPP
                     PPTIPPARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVS
                     FVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMR
                     KNVPKVLVVVTDGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHV
                     FIVDDFESFEKIEDNLITFVCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQ
                     GVSLESGSFPSYSAYRIQKNAFVNQPTADLHPNGLPPSYTIILLFRLLPETPSDPFAI
                     WQITDRDYKPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTEEVKTLFYGSFHKVHIV
                     VTSKSVKIYIDCYEIIEKDIKEAGNITTDGYEILGKLLKGERKSAAFQIQSFDIVCSP
                     VWTSRDRCCDIPSRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGIS
                     GAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGL
                     PGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPS
                     GLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPP
                     GPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGP
                     PGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYP
                     GSG"
     exon            386..502
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            503..646
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            647..706
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            707..970
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            971..1135
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            1136..1309
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            1310..1600
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            1601..2203
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            2204..2476
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            2477..2749
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            2750..3022
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            3023..3295
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            3296..3562
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            3563..3755
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            3756..3877
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            3878..4027
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            4028..4147
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            4148..4312
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            4313..4459
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            4460..4599
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            4600..4729
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            4730..4872
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            4873..5002
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            5003..5139
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            5140..5269
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            5270..5409
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            5410..5542
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            5543..5563
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            5564..5706
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            5707..5836
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            5837..5976
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            5977..6106
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            6107..6249
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            6250..6379
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            6380..6522
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            6523..6652
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            6653..6772
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            6773..6919
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            6920..7036
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            7037..7183
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            7184..7258
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            7259..7398
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            7399..7522
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            7523..7666
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            7667..7831
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            7832..7870
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            7871..8009
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            8010..8152
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            8153..8262
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            8263..8412
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            8413..8490
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            8491..8577
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            8578..8631
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            8632..8727
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            8728..8781
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            8782..8835
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            8836..8889
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            8890..8961
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            8962..8997
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            8998..9064
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            9065..9253
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            9254..9322
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            9323..9493
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            9494..11725
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      11704..11709
                     /regulatory_class="polyA_signal_sequence"
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /note="hexamer: AATAAA"
     polyA_site      11725
                     /gene="COL12A1"
                     /gene_synonym="BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1;
                     EDSMYP; UCMD2"
                     /note="major polyA site"
ORIGIN      
        1 ccacttggct aaggcgaacc gccccagacg cgtccgcgcg ccggcagctg caggctcagg
       61 ccatctccag tcttcctgcc gcgcccgcct ctcctcctgg gattctcctc ctcctcctgg
      121 acttccccgc agctgcccac gcctcggcgg ccgccaggtg ctcctggagt gcagcgccta
      181 tcgccggggc gtgtgggggc cacaccgagc accagcttct ccgacgccgg gaagccgctg
      241 tcgccgccgc tacctctccc tgttgccgcc gcctcagatc tcttcatgcc gctgtaagct
      301 cggaggccaa ggatgcggag taggcttccc ccagcgcttg ccgccctggg cgcggccctg
      361 ctcctgtctt ccattgaggc agaagttgac ccaccttcag acttgaattt taaaattata
      421 gatgaaaata ctgttcatat gtcatgggca aaaccagttg atccaattgt gggttacaga
      481 ataacggtgg accctacaac ggatgggcct actaaagaat ttaccctttc agctagtacc
      541 actgaaactt tattgtcaga acttgtacct gaaacagagt atgtggtgac aataacttca
      601 tatgatgaag tagaagaaag tgtaccagtt ataggacaac taacaattca aacaggtagt
      661 tcgacaaagc cagtggagaa gaaacctgga aaaaccgaga tacaaaaatg ctctgtcagt
      721 gcctggactg atttggtttt cctcgtggat ggctcttgga gtgtgggaag aaataatttc
      781 aagtacattt tagacttcat tgctgctctt gtgtctgctt ttgacattgg ggaagagaag
      841 acaagagttg gagttgttca atacagctct gataccagga ctgaatttaa cttaaatcag
      901 tactaccaaa gggatgaact tcttgctgca ataaaaaaaa ttccatataa aggtggcaac
      961 acaatgacag gggatgccat tgattattta gttaaaaata ctttcacgga atctgctggg
     1021 gcaagagttg gctttcctaa agtggcaatt attattacgg atggaaaatc ccaggatgaa
     1081 gtggaaattc cagcaagaga gcttcgtaat gttggagttg aagttttctc cttgggcatt
     1141 aaagctgcag atgcaaaaga actcaaacaa attgcctcca caccttcact gaaccatgtt
     1201 ttcaatgtgg ccaactttga tgcaattgtg gatattcaga atgagatcat ctcccaggtg
     1261 tgctcaggtg ttgatgaaca acttggtgaa ttggttagtg gagaagaagt tgttgagcct
     1321 ccttcaaatt tgattgccat ggaagtctct tcaaaatatg ttaagctaaa ttggaatcca
     1381 tctcctagtc cagtgactgg ctacaaagtc atcctcacac caatgactgc aggaagccga
     1441 cagcacgctc tgagtgtggg gcctcagaca accacgctca gtgttcgcga cctctcagca
     1501 gacacagaat accagatcag tgtttccgcc atgaagggaa tgacatccag tgaacccatt
     1561 tcaataatgg agaagactca gccaatgaaa gttcaagtgg aatgctcacg tggtgtggat
     1621 ataaaagccg atattgtgtt tttggttgat ggctcctata gcattgggat tgcaaacttt
     1681 gttaaagtta gagccttttt ggaagttctt gtaaaaagtt ttgaaatttc accaaatagg
     1741 gtccagatta gtcttgtgca atacagccgg gatcctcata ctgagttcac tttgaaaaaa
     1801 ttcaccaaag ttgaagatat aattgaagca ataaacacct tcccttacag aggaggatct
     1861 acaaatactg gcaaagcaat gacttatgtc agagagaaaa tatttgtgcc tagcaaggga
     1921 tcaagaagca atgtgccaaa ggtcatgatt cttatcacgg atgggaaatc atcagatgct
     1981 ttcagagatc ctgcgataaa actgaggaat tcagatgttg aaatctttgc agttggtgtg
     2041 aaggatgccg ttcgctcaga attggaagct attgcctctc ctcctgcaga gacccatgtg
     2101 ttcacagtgg aagattttga tgcttttcag aggatatctt ttgaactcac acagtctatc
     2161 tgccttagaa ttgagcaaga attggcagct ataaagaaga aagcttacgt ccctccaaag
     2221 gatcttagtt tttcagaagt gacttcttat ggtttcaaaa ccaactggtc tccagctgga
     2281 gaaaatgttt tttcatatca catcacctac aaggaagcgg ctggggatga tgaggtcact
     2341 gtggtggagc cagcatcgag caccagtgtt gttctcagca gcctgaagcc agagaccttg
     2401 tatttggtca atgtgactgc ggagtatgag gatggcttca gcattccctt agctggagag
     2461 gagaccaccg aagaagtaaa aggagcacct cgaaacctaa aggtgacaga tgagactaca
     2521 gatagtttca aaattacttg gactcaagct ccagggagag ttttaagata tcgaattata
     2581 tatagaccag ttgctggtgg agagagcaga gaagttacca ccccacccaa tcagaggagg
     2641 agaacactgg agaacttgat tccagacacg aaatatgaag tatctgtaat tcctgaatat
     2701 ttctcaggac ctggtactcc attaactgga aatgcagcca ctgaagaagt tagagggaat
     2761 ccaagagact taagagtttc tgaccctacg acgtctacta tgaaattatc ttggagtggg
     2821 gcaccaggaa aagtgaaaca gtatctcgtc acatataccc cagtggcagg gggtgaaact
     2881 caagaggtca ctgtgagggg agatacaacc aatacggtgc tgcagggatt gaaggaaggg
     2941 acacaatacg ccttatctgt gacagccttg tatgcgtctg gggctggaga cgccctcttt
     3001 ggtgaaggaa caacacttga agaacgtggt tctcctcaag atttagttac taaagacatc
     3061 actgacacat caattggggc ttattggaca tctgctccag gaatggttcg cggttacagg
     3121 gtctcatgga aatcacttta tgatgatgtt gacactggag agaaaaatct gcctgaagat
     3181 gcaattcata cgatgataga aaatctgcag ccagagacca aatacagaat ttcagtattt
     3241 gccacttaca gcagtggaga aggagaacct ttgactggag atgccacaac tgaattatct
     3301 caagattcca aaaccctgaa agtagatgaa gaaacagaaa acacaatgag agttacatgg
     3361 aaaccagcac cagggaaagt cgtcaactac cgtgttgtct atcgccctca tgggagaggg
     3421 aagcaaatgg ttgctaaggt gccccccaca gtcacttcga cagtgttaaa gcgacttcag
     3481 ccacagacca catatgacat cacagttctt cctatttaca agatgggaga aggaaagctt
     3541 aggcaaggat caggaacaac agcttctcgg tttaagtctc ctagaaacct caaaacatct
     3601 gacccaacca tgtcaagctt ccgagtgact tgggagcctg cccctgggga agtgaagggt
     3661 tataaagtca cattccaccc tacgggggat gacagaagac tgggggagtt agtggttgga
     3721 ccctatgaca acacagttgt tttggaggaa cttagggctg gtaccaccta taaagtaaat
     3781 gtttttggaa tgtttgatgg aggagaaagc tcaccacttg ttggacaaga aatgacaacc
     3841 ctttccgaca caactgttat gccaatttta tcttctggga tggagtgtct caccagagct
     3901 gaggcagaca ttgtgttgct ggtggatgga tcatggagca tcggccgggc aaattttaga
     3961 accgtgagga gtttcatttc tcgtattgtg gaagtctttg acattggccc caaaagagta
     4021 caaattgctc ttgctcagta tagtggggat cccagaacag agtggcagtt aaatgcacac
     4081 agagacaaga agagcttgtt gcaagctgtg gcaaacttgc cgtacaaagg aggcaatact
     4141 ctcacaggca tggctttgaa tttcattcgc caacagaact tcaggaccca agctggcatg
     4201 agacctcgag ctcgaaaaat tggtgtgctc attactgatg gaaaatcaca agacgatgtt
     4261 gaagcacctt caaagaaact caaggatgag ggagtggagc tgtttgctat tggtattaaa
     4321 aatgctgatg aagtcgaatt aaagatgatt gcaactgatc ctgatgatac ccatgcatac
     4381 aatgtggcag attttgagtc actctccagg atagtggatg atctcaccat taatttgtgt
     4441 aacagtgtca aaggtccagg tgatttggaa gcaccttcta acttagttat ttctgagcga
     4501 acccatcgtt cttttagagt gagctggaca ccaccttctg acagtgtgga tcgatataag
     4561 gtggaatact atccagtttc tggagggaaa cgtcaagaat tttatgtgag tcgaatggaa
     4621 actagcacag tgctgaaaga tctgaaacct gaaactgaat atgttgtcaa tgtgtattct
     4681 gtggtagaag atgaatatag tgagcctctg aaggggacag aaaaaacctt gccagtgcct
     4741 gtagtcagcc tgaatattta tgatgttggc cctaccacca tgcatgtgca gtggcagcct
     4801 gtgggaggag ctactggcta catcttgtca tacaaacctg ttaaggacac agagccaaca
     4861 agacccaaag aggtgcgttt ggggccaaca gtgaatgaca tgcagctgac tgaccttgtt
     4921 cccaacacgg agtatgcagt cacagtccag gctgtcctgc acgacctcac tagtgaacct
     4981 gtcactgttc gggaagtcac cttgccttta cccagacctc aggatctgaa actcagagat
     5041 gtgactcaca gcactatgaa tgtcttttgg gaacctgtgc ctggaaaagt gcgtaaatat
     5101 attgttcgat acaaaacacc agaagaggat gtcaaagagg tagaggtgga cagatcagag
     5161 accagcactt ccctcaaaga cctcttctca cagaccttgt acacagtcag cgtttctgca
     5221 gtacatgacg agggggagtc tcctccagtg actgctcaag aaactacccg acccgtgcca
     5281 gccccaacaa acttaaagat tactgaagta acatcagagg gtttcagagg gacttgggat
     5341 catggagctt cagatgtgtc tctctacaga ataacttggg caccttttgg aagctcagat
     5401 aagatggaga ccatcttaaa tggagatgaa aacactttgg tgttcgaaaa cctgaacccc
     5461 aacaccatct atgaagtttc cattactgcc atctatcctg atgagtcaga aagtgatgac
     5521 ctgattggca gtgagcgcac actgcctatc ttaacaacac aagctcccaa aagtggccca
     5581 cgaaaccttc aagtgtacaa tgcaacatct aacagcctga ctgttaagtg ggatcctgct
     5641 agtggtcgtg tgcagaaata taggatcact tatcagcctt ccacagggga aggcaatgag
     5701 caaacgacca caataggagg acggcagaac agtgtggtcc tgcagaaact gaagccagac
     5761 actccttaca ctatcaccgt atcctctctg tatcctgatg gtgaaggagg tcggatgacg
     5821 ggaagaggca agaccaaacc tctaaacact gtaaggaacc tgagagtgta tgacccttct
     5881 accagcacct tgaatgtccg ctgggaccat gcagagggaa atcctcgtca gtacaagctc
     5941 ttctatgcac cagcagcagg tggtccagag gaactggtac caatccccgg gaataccaat
     6001 tatgccattc ttaggaatct gcagccagat acctcataca ctgtgactgt agttcccgtt
     6061 tatactgaag gtgatggggg acgcacatca gatactggaa ggacattgat gagaggactg
     6121 gcaagaaatg tccaagtata caatcctaca cctaacagcc tcgatgttcg ctgggaccct
     6181 gctccaggac ctgtgctgca atatcgcgtt gtgtattctc ctgtggatgg cacaagaccc
     6241 tcagaatcta tagtagtgcc aggaaacacg cgcatggtgc atctggagcg gctgattccg
     6301 gacacactct attccgtgaa ccttgtggct ctgtactcgg atggagaggg aaatcccagc
     6361 cctgcccagg gccgaacgct accacgcagt ggaccaagga acctgagagt ctttggtgaa
     6421 acaaccaata gcctctcggt agcctgggat catgctgatg ggccagttca gcagtacagg
     6481 atcatctatt ctcccactgt tggtgatcca attgatgaat ataccacagt cccaggcaga
     6541 agaaacaatg taatactgca gcccctgcaa cctgacactc catataaaat tactgttatt
     6601 gctgtttatg aagatggaga tggtggccat ctaacaggaa atggaagaac tgtgggactc
     6661 cttcctcctc agaacataca catctctgac gaatggtata caagattcag ggtgtcctgg
     6721 gatccttcac cttctccagt tcttggatat aaaatagtat ataagccagt gggttccaat
     6781 gagcccatgg aagcctttgt tggagaaatg acatcatata ccttacacaa tctcaatccc
     6841 agcaccacct acgatgtgaa tgtttatgct caatatgatt ctggactcag tgtccccttg
     6901 acagatcaag gcactacatt atatttaaat gtaacagatc tgaaaactta ccagattggg
     6961 tgggatacat tctgtgtcaa atggtcacct caccgggcag ccacctccta caggctaaaa
     7021 ctaagccctg cagatggaac aaggggacaa gaaattacag tgcgtggatc agaaaccagt
     7081 cactgcttca ctggcctttc accagacact gattatggtg tcactgtttt tgtgcagaca
     7141 ccaaatctcg agggaccagg agtctctgtt aaagaacata ccactgtgaa accaacagaa
     7201 gcccctacag agccacccac acctcctccc cctcccacca ttccaccagc ccgggatgta
     7261 tgcaaagggg ccaaggcaga tattgtgttc ttgactgatg cctcctggag cattggggac
     7321 gataatttta acaaagttgt aaaattcatc ttcaatactg tgggaggctt tgatgaaatc
     7381 agtcctgctg ggattcaggt ttcatttgtg caatacagcg atgaggtcaa gtctgagttc
     7441 aagctgaaca cgtacaatga caaggcccta gcccttgggg ccctccagaa tattaggtac
     7501 agaggaggaa acacaagaac aggcaaggcc ctcacgttta tcaaggagaa agtcttgact
     7561 tgggagagcg gcatgaggaa gaatgtccct aaggtgttgg ttgtggtcac ggacggtcgg
     7621 tcccaggatg aggtcaagaa ggcggctttg gtcatccagc agtcagggtt cagtgtcttt
     7681 gtagttggtg tggctgatgt cgactacaat gagcttgcca acattgccag caaaccaagt
     7741 gaacggcacg tgttcattgt ggacgacttt gaatcttttg agaagatcga agacaatctt
     7801 attacatttg tttgtgaaac tgccacttca agttgtcctc tcatttattt ggatggctac
     7861 acctcaccag gttttaaaat gcttgaagca tacaacctga cagaaaagaa ttttgcttct
     7921 gtacaaggag tatctttgga gtcagggtct ttccccagct actcagcata caggattcag
     7981 aagaatgcgt ttgtgaatca gcctacagca gacctacacc caaatggact ccctccttca
     8041 tacacgatta tattattatt cagacttctc ccagaaactc ccagtgaccc ttttgcaatt
     8101 tggcaaatca cagacagaga ctacaaacca caagttggag tgattgcaga tccttctagc
     8161 aagacgttat cattctttaa caaggataca agaggcgagg tgcaaactgt tacatttgac
     8221 acagaagaag taaagacatt attttatgga agttttcaca aggttcatat tgtagtgacc
     8281 tcaaaaagtg ttaagattta cattgactgc tatgaaatta tagaaaaaga catcaaggaa
     8341 gctggaaata taacaactga tggttatgaa attcttggaa aactccttaa aggggaaagg
     8401 aaatcagccg cattccaaat ccagagtttt gacattgtct gcagtccagt gtggaccagt
     8461 agagacagat gctgtgatat tccctctagg agagatgagg gaaaatgccc tgcttttcca
     8521 aattcttgca catgtacaca ggacagcgtt ggacctccag gacctccagg ccctgcagga
     8581 ggacctggtg ctaaaggtcc cagaggtgaa agaggtatca gtggggcaat tgggccccct
     8641 ggtcctcgtg gagacatagg tcctccaggc ccccagggtc ctccaggccc tcagggaccc
     8701 aatggactct ctattccggg agagcaaggt cgccaaggga tgaaaggtga tgctggagag
     8761 ccaggacttc caggccgaac aggaacccca ggattacctg gcccaccagg accaatggga
     8821 cctccaggag acagaggctt cactggaaaa gacggtgcaa tgggacccag gggcccacca
     8881 gggccgccgg gaagcccagg ctccccagga gtcacaggac caagtgggaa gccaggaaaa
     8941 cctggagatc atggcagacc aggtccatct gggttgaaag gagaaaaagg tgatagggga
     9001 gacattgctt cccagaacat gatgcgagca gttgcaagac aagtctgtga acaattgata
     9061 agtggtcaga tgaacagatt caatcagatg ctgaatcaga ttccaaatga ttaccagtcc
     9121 agtcgcaacc agccaggccc gccgggtcca ccgggacctc ctggtagcgc aggagccaga
     9181 ggagaacctg ggcctggggg gcggccaggc ttcccgggca caccagggat gcagggaccc
     9241 cctggggaac gaggtttgcc aggagagaaa ggtgaaaggg gtactggatc ttcaggacct
     9301 cgggggctgc ctggcccccc aggtccacaa ggagaatcca gaacaggtcc accagggtcc
     9361 acaggttcaa gaggtccccc tggcccccct ggccgtcctg gaaactcagg tatccgagga
     9421 cccccaggtc ctcctggata ctgtgattct tctcagtgtg ccagcatccc atacaacggg
     9481 caaggctatc caggttccgg ctaacacatt ttctaagtcg ccagtgctgc ttacagtttg
     9541 aatacatgaa aatcctgttt ctgagatgtt tgcgcacgtg cttattagga aatgagtctg
     9601 tatggaaatc tcaccacaga taatggttaa cgaaccgggt cgacatcaca aaggagggtg
     9661 gagactcttt ttactaactt gaatgagaca aaagcagtgg tgtcagttta taatcctgat
     9721 gcatttcagt aataatgtag aaaaacatta ttttaaaaaa gttccaacac acagccatga
     9781 ggagcctcag ttttgaaaga ggtgcataat aaaactacta accagaggag tctatgccat
     9841 tttaagaaaa acaattaacc tggttaaaga gaaatgtctt atgtaaataa taaactaatt
     9901 gtggcttgta aatgatttgt atgtgatcct gtcgactaaa atcacttaac aattctacaa
     9961 taagcttctg catcaaagcc tgccgcttgc tctatgccgg aataacacca aatggaatct
    10021 cctcatctct tgcttgttag cgatgtgtct gattcagggc atctgtcttt ttgttacttt
    10081 tttgtccgtg tcctctcatt tgggttttgt aactgcaatt ttcaaaccaa agtttaaaat
    10141 caccttttct tcctgttttg ctgtagtcac tggtgttcct cacccaccag ctgtaactca
    10201 gtttgtgtga ggtacagcca cagaagatgt catgtactgt atattacctg gtgatagttg
    10261 cttttcaccc cccgagttca gtttctagga gccaatgaaa cttcccctca cctcctcatc
    10321 tttccaagtt gttctttgaa ttgaggagtt tgaaggcata aacagttact tggggatttg
    10381 cgaaaatcct acttagttac tgcgtttaca gttctttggc ccagtctctg acccttccca
    10441 agtatttgtg caatgattgt gtttactgct ggatttttga aggttttttt ttttaagaaa
    10501 gtgccatttc attatttgat tatcaccaaa ttatctggaa ataattggga cattgtaact
    10561 tatctattta tagttatgag attaagactg gagtgccatc accgcgggtg atgatttagc
    10621 ttttgctgtg tgtgtgtgtg tgtgccttcc aaatcatgcc ataattgtaa tgttgaatcg
    10681 gacagagcct tacgtgcccg agggcggggc ctacctgcct gagcgcgagc ccttcatcgt
    10741 gccggtggag cccgagcgga cagcggaata cgaggactac ggcgcagacg agcctgcaga
    10801 ggagcctcct gagccccacc ggcgctggcg gcgcgccctg ccccacggac ccgggcagtg
    10861 aaccagagat cacgcgccgc gccgcgaggc ttgggggagg tgttgaaatt ctcatttaca
    10921 ggtcagatag agcagtgtac gtcttttctg aggtgtttct tccagcgttg ctcatccagg
    10981 agtacccttt ctgattgtag agaaccttgt ttctgcagga agcctagctc caagcacgca
    11041 gtctgtagac atttttgcct ttgcccttga aatgcttgca aaatactttg ttaacaaaag
    11101 ctgcaaagag agaacatgcc gtgtgccttt agttagcaca gcgggcagcc tcagtgaaac
    11161 tcttaggtta agcagttaag tcctggaacc cagagctgct gtgtatttcg agcgggcagt
    11221 ttatcttttg ctatacttat tttcaattca attacaccac gattcaaata attcccctcc
    11281 taaaaccaaa aaggagggaa acgtcaactc cattgcaatt acttatcttc ctcttctatc
    11341 tctgttatac gccggggcat agaatgctcg tatacatctc tttaacaacc acaaacctta
    11401 agccatgtag atgaagttag tgcatcaacg ggatacagtt ccatattgcc ttaaacctcc
    11461 ttgttttaga cacactaaca tttataccaa attgcagatt attctgcaga gagggaattg
    11521 catgtttgtg ttgtatattt agtatgaact tttttcagaa tataatattt cttagttatc
    11581 aaaagtagtt ggaaaacatt tgcaagacta tgaacataga attgctgctt ttatatttta
    11641 actgcagatt gtgaatttca ctgccttata ttatttattt ctgaaacaaa agaggcattt
    11701 ttcaataaaa ctactgaaaa tttga
//
