LOCUS       XM_047431062            2666 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens cochlin (COCH), transcript variant X1,
            mRNA.
ACCESSION   XM_047431062
VERSION     XM_047431062.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000014.9) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2666
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
     gene            1..2666
                     /gene="COCH"
                     /gene_synonym="COCH-5B2; COCH5B2; DFNA9; DFNB110"
                     /note="cochlin; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 1 mRNA, 10 ESTs, 41 long
                     SRA reads, and 99% coverage of the annotated genomic
                     feature by RNAseq alignments, including 3 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:1690"
                     /db_xref="HGNC:HGNC:2180"
                     /db_xref="MIM:603196"
     CDS             57..1961
                     /gene="COCH"
                     /gene_synonym="COCH-5B2; COCH5B2; DFNA9; DFNB110"
                     /codon_start=1
                     /product="cochlin isoform X1"
                     /protein_id="XP_047287018.1"
                     /db_xref="GeneID:1690"
                     /db_xref="HGNC:HGNC:2180"
                     /db_xref="MIM:603196"
                     /translation="MSAAWIPALGLGVCLLLLPGPAGSEGAGEWGSWGASRRSQGLST
                     SGYKRDSDPAPWASALPPEEEGAKVEPPRGAPALTPAADLLLLTCFSHAPIAITCFTR
                     GLDIRKEKADVLCPGGCPLEEFSVYGNIVYASVSSICGAAVHRGVISNSGGPVRVYSL
                     PGRENYSSVDANGIQSQMLSRWSASFTVTKGKSSTQEATGQAVSTAHPPTGKRLKKTP
                     EKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASE
                     HPKIEFYLKNFTSAKDVLFAIKEVGFRGGNSNTDVAERMSSTTVDSEERLLRGKALKH
                     TAQKFFTVDAGVRKGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEE
                     LGMVQDVTFVDKAVCRNNGFFSYHMPNWFGTTKYVKPLVQKLCTHEQMMCSKTCYNSV
                     NIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFSFTDY
                     STKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIRESPNKNFLVIVTDGQSYDDV
                     QGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEPIVSDVIRG
                     ICRDFLESQQ"
     polyA_site      2666
                     /gene="COCH"
                     /gene_synonym="COCH-5B2; COCH5B2; DFNA9; DFNB110"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 gcactcgggc gcagccgggt ggatctcgag caggtgtgag cagcctatca gtcaccatgt
       61 ccgcagcctg gatcccggct ctcggcctcg gtgtgtgtct gctgctgctg ccggggcccg
      121 cgggcagcga gggagccggt gagtggggga gctggggtgc gtccaggcgg tcgcaggggc
      181 tgagcaccag cgggtacaag cgggactcag atccagcccc ttgggcttca gccctaccgc
      241 ctgaggagga aggcgcgaag gttgagccgc cgcgtggcgc gcccgcgtta acccctgcag
      301 ccgatctgct cctgctcacc tgtttctccc atgctcccat tgctatcaca tgttttacca
      361 gaggcttgga catcaggaaa gagaaagcag atgtcctctg cccagggggc tgccctcttg
      421 aggaattctc tgtgtatggg aacatagtat atgcttctgt atcgagcata tgtggggctg
      481 ctgtccacag gggagtaatc agcaactcag ggggacctgt acgagtctat agcctacctg
      541 gtcgagaaaa ctattcctca gtagatgcca atggcatcca gtctcaaatg ctttctagat
      601 ggtctgcttc tttcacagta actaaaggca aaagtagtac acaggaggcc acaggacaag
      661 cagtgtccac agcacatcca ccaacaggta aacgactaaa gaaaacaccc gagaagaaaa
      721 ctggcaataa agattgtaaa gcagacattg catttctgat tgatggaagc tttaatattg
      781 ggcagcgccg atttaattta cagaagaatt ttgttggaaa agtggctcta atgttgggaa
      841 ttggaacaga aggaccacat gtgggccttg ttcaagccag tgaacatccc aaaatagaat
      901 tttacttgaa aaactttaca tcagccaaag atgttttgtt tgccataaag gaagtaggtt
      961 tcagaggggg taattccaat acagatgtgg cagaaagaat gagtagcact accgttgact
     1021 ctgaagagag acttcttaga ggaaaagcct tgaagcatac tgctcagaaa ttcttcacgg
     1081 tagatgctgg agtaagaaaa gggatcccca aagtggtggt ggtatttatt gatggttggc
     1141 cttctgatga catcgaggaa gcaggcattg tggccagaga gtttggtgtc aatgtattta
     1201 tagtttctgt ggccaagcct atccctgaag aactggggat ggttcaggat gtcacatttg
     1261 ttgacaaggc tgtctgtcgg aataatggct tcttctctta ccacatgccc aactggtttg
     1321 gcaccacaaa atacgtaaag cctctggtac agaagctgtg cactcatgaa caaatgatgt
     1381 gcagcaagac ctgttataac tcagtgaaca ttgcctttct aattgatggc tccagcagtg
     1441 ttggagatag caatttccgc ctcatgcttg aatttgtttc caacatagcc aagacttttg
     1501 aaatctcgga cattggtgcc aagatagctg ctgtacagtt tacttatgat cagcgcacgg
     1561 agttcagttt cactgactat agcaccaaag agaatgtcct agctgtcatc agaaacatcc
     1621 gctatatgag tggtggaaca gctactggtg atgccatttc cttcactgtt agaaatgtgt
     1681 ttggccctat aagggagagc cccaacaaga acttcctagt aattgtcaca gatgggcagt
     1741 cctatgatga tgtccaaggc cctgcagctg ctgcacatga tgcaggaatc actatcttct
     1801 ctgttggtgt ggcttgggca cctctggatg acctgaaaga tatggcttct aaaccgaagg
     1861 agtctcatgc tttcttcaca agagagttca caggattaga accaattgtt tctgatgtca
     1921 tcagaggcat ttgtagagat ttcttagaat cccagcaata atgcaaaata agtttaaaag
     1981 ggaatctgtg gcattcaacc gataaacaga agatcactaa gagatgaaaa aaagctactc
     2041 ttggagctca cttcccccaa caagagcacc acattcctaa cccctaaggc agcacacaga
     2101 gtccaaaaaa aaaaaaaaaa aaaaaaaaaa gaagaagaag aagagaaaaa aaaaaacttt
     2161 tttgaaagat cagactccac attggcttaa agacacctaa aaacagatat acgctcagtt
     2221 cacatccagt acaggccaca aatactggag tccttttttc tttgtcccac aaaatacagt
     2281 aattacagtt aacttaatga gcttgacatt aagatgtgat ttccaccaat ttgtgcctgc
     2341 cccagatagc cttcaccagg cagatcacat gtagtgtcat atcagtaacc tttctgatgg
     2401 cagtgatgca gaccctcttt ctgtccaagc aaatcttgtt acgatgcaag tttttgttga
     2461 ttcatacaaa tactttggca agagcatcag ctcctgcact agctatatat gcttttgacg
     2521 agtggaaagc aacatcataa attgattcat ccaatttctt tctgtgagct gttatttctt
     2581 gcacacatgt cttgctgtct aaattccata atctgatgga acagtcatgg cctgtaaaag
     2641 aacaaataaa atttgttact gagtaa
//
