LOCUS       NM_001289080            4065 bp    mRNA    linear   PRI 23-MAR-2024
DEFINITION  Homo sapiens contactin 6 (CNTN6), transcript variant 2, mRNA.
ACCESSION   NM_001289080
VERSION     NM_001289080.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4065)
  AUTHORS   Zhang,H.Y., Wu,F.Y., Zhang,C.X., Wu,C.Y., Cui,R.J., Liu,X.Y.,
            Yang,L., Zhang,Y., Sun,F., Cheng,F., Yang,R.M., Song,H.D. and
            Zhao,S.X.
  TITLE     Contactin 6, A Novel Causative Gene for Congenital Hypothyroidism,
            Mediates Thyroid Hormone Biosynthesis Through Notch Signaling
  JOURNAL   Thyroid 34 (3), 324-335 (2024)
   PUBMED   38183624
  REMARK    GeneRIF: Contactin 6, A Novel Causative Gene for Congenital
            Hypothyroidism, Mediates Thyroid Hormone Biosynthesis Through Notch
            Signaling.
REFERENCE   2  (bases 1 to 4065)
  AUTHORS   Repnikova,E.A., Lyalin,D.A., McDonald,K., Astbury,C.,
            Hansen-Kiss,E., Cooley,L.D., Pfau,R., Herman,G.E., Pyatt,R.E. and
            Hickey,S.E.
  TITLE     CNTN6 copy number variations: Uncertain clinical significance in
            individuals with neurodevelopmental disorders
  JOURNAL   Eur J Med Genet 63 (1), 103636 (2020)
   PUBMED   30836150
  REMARK    GeneRIF: CNTN6 copy number variations: Uncertain clinical
            significance in individuals with neurodevelopmental disorders.
REFERENCE   3  (bases 1 to 4065)
  AUTHORS   Tassano,E., Uccella,S., Giacomini,T., Severino,M., Fiorio,P.,
            Gimelli,G. and Ronchetto,P.
  TITLE     Clinical and Molecular Characterization of Two Patients with CNTN6
            Copy Number Variations
  JOURNAL   Cytogenet Genome Res 156 (3), 144-149 (2018)
   PUBMED   30508811
  REMARK    GeneRIF: this study describes of 2 boys with intellectual
            disability, attention-deficit hyperactivity disorder harboring a
            3p26.3 microdeletion and a 3p26.3 microduplication, which are both
            paternally inherited and include only the CNTN6 gene.
REFERENCE   4  (bases 1 to 4065)
  AUTHORS   Huang,A.Y., Yu,D., Davis,L.K., Sul,J.H., Tsetsos,F., Ramensky,V.,
            Zelaya,I., Ramos,E.M., Osiecki,L., Chen,J.A., McGrath,L.M.,
            Illmann,C., Sandor,P., Barr,C.L., Grados,M., Singer,H.S.,
            Nothen,M.M., Hebebrand,J., King,R.A., Dion,Y., Rouleau,G.,
            Budman,C.L., Depienne,C., Worbe,Y., Hartmann,A., Muller-Vahl,K.R.,
            Stuhrmann,M., Aschauer,H., Stamenkovic,M., Schloegelhofer,M.,
            Konstantinidis,A., Lyon,G.J., McMahon,W.M., Barta,C., Tarnok,Z.,
            Nagy,P., Batterson,J.R., Rizzo,R., Cath,D.C., Wolanczyk,T.,
            Berlin,C., Malaty,I.A., Okun,M.S., Woods,D.W., Rees,E., Pato,C.N.,
            Pato,M.T., Knowles,J.A., Posthuma,D., Pauls,D.L., Cox,N.J.,
            Neale,B.M., Freimer,N.B., Paschou,P., Mathews,C.A., Scharf,J.M. and
            Coppola,G.
  CONSRTM   Tourette Syndrome Association International Consortium for Genetics
            (TSAICG); Gilles de la Tourette Syndrome GWAS Replication
            Initiative (GGRI)
  TITLE     Rare Copy Number Variants in NRXN1 and CNTN6 Increase Risk for
            Tourette Syndrome
  JOURNAL   Neuron 94 (6), 1101-1111 (2017)
   PUBMED   28641109
  REMARK    GeneRIF: CNTN6 copy number variants (duplications) were associated
            with increased risk of Tourette syndrome.
REFERENCE   5  (bases 1 to 4065)
  AUTHORS   Mercati,O., Huguet,G., Danckaert,A., Andre-Leroux,G., Maruani,A.,
            Bellinzoni,M., Rolland,T., Gouder,L., Mathieu,A., Buratti,J.,
            Amsellem,F., Benabou,M., Van-Gils,J., Beggiato,A., Konyukh,M.,
            Bourgeois,J.P., Gazzellone,M.J., Yuen,R.K., Walker,S., Delepine,M.,
            Boland,A., Regnault,B., Francois,M., Van Den Abbeele,T.,
            Mosca-Boidron,A.L., Faivre,L., Shimoda,Y., Watanabe,K., Bonneau,D.,
            Rastam,M., Leboyer,M., Scherer,S.W., Gillberg,C., Delorme,R.,
            Cloez-Tayarani,I. and Bourgeron,T.
  TITLE     CNTN6 mutations are risk factors for abnormal auditory sensory
            perception in autism spectrum disorders
  JOURNAL   Mol Psychiatry 22 (4), 625-633 (2017)
   PUBMED   27166760
  REMARK    GeneRIF: Clinical investigations of the patients carrying CNTN5 or
            CNTN6 variants showed that they were hypersensitive to sounds (a
            condition called hyperacusis) and displayed changes in wave latency
            within the auditory pathway.
REFERENCE   6  (bases 1 to 4065)
  AUTHORS   Barber,M.J., Mangravite,L.M., Hyde,C.L., Chasman,D.I., Smith,J.D.,
            McCarty,C.A., Li,X., Wilke,R.A., Rieder,M.J., Williams,P.T.,
            Ridker,P.M., Chatterjee,A., Rotter,J.I., Nickerson,D.A.,
            Stephens,M. and Krauss,R.M.
  TITLE     Genome-wide association of lipid-lowering response to statins in
            combined study populations
  JOURNAL   PLoS One 5 (3), e9763 (2010)
   PUBMED   20339536
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 4065)
  AUTHORS   Gratacos,M., Costas,J., de Cid,R., Bayes,M., Gonzalez,J.R.,
            Baca-Garcia,E., de Diego,Y., Fernandez-Aranda,F.,
            Fernandez-Piqueras,J., Guitart,M., Martin-Santos,R., Martorell,L.,
            Menchon,J.M., Roca,M., Saiz-Ruiz,J., Sanjuan,J., Torrens,M.,
            Urretavizcaya,M., Valero,J., Vilella,E., Estivill,X. and
            Carracedo,A.
  CONSRTM   Psychiatric Genetics Network Group
  TITLE     Identification of new putative susceptibility genes for several
            psychiatric disorders by association analysis of regulatory and
            non-synonymous SNPs of 306 genes involved in neurotransmission and
            neurodevelopment
  JOURNAL   Am J Med Genet B Neuropsychiatr Genet 150B (6), 808-816 (2009)
   PUBMED   19086053
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   8  (bases 1 to 4065)
  AUTHORS   Manderson,E.N., Birch,A.H., Shen,Z., Mes-Masson,A.M., Provencher,D.
            and Tonin,P.N.
  TITLE     Molecular genetic analysis of a cell adhesion molecule with
            homology to L1CAM, contactin 6, and contactin 4 candidate
            chromosome 3p26pter tumor suppressor genes in ovarian cancer
  JOURNAL   Int J Gynecol Cancer 19 (4), 513-525 (2009)
   PUBMED   19509545
  REMARK    GeneRIF: results do not support the candidacy of CHL1, CNTN6, and
            CNTN4 as tumor suppressor genes in the 3p26-pter region in ovarian
            cancer
REFERENCE   9  (bases 1 to 4065)
  AUTHORS   Kamei,Y., Tsutsumi,O., Taketani,Y. and Watanabe,K.
  TITLE     cDNA cloning and chromosomal localization of neural adhesion
            molecule NB-3 in human
  JOURNAL   J Neurosci Res 51 (3), 275-283 (1998)
   PUBMED   9486763
REFERENCE   10 (bases 1 to 4065)
  AUTHORS   Walsh,F.S. and Doherty,P.
  TITLE     Glycosylphosphatidylinositol anchored recognition molecules that
            function in axonal fasciculation, growth and guidance in the
            nervous system
  JOURNAL   Cell Biol Int Rep 15 (11), 1151-1166 (1991)
   PUBMED   1838307
  REMARK    Review article
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BC113118.1, DB170583.1,
            AB003592.1, CN364480.1, AC034192.5 and AC026214.4.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 22, 2018 this sequence version replaced NM_001289080.1.
            
            Summary: The protein encoded by this gene is a member of the
            immunoglobulin superfamily. It is a glycosylphosphatidylinositol
            (GPI)-anchored neuronal membrane protein that functions as a cell
            adhesion molecule. It may play a role in the formation of axon
            connections in the developing nervous system. Alternative splicing
            results in multiple transcript variants. [provided by RefSeq, Jan
            2014].
            
            Transcript Variant: This variant (2) differs in the 5' UTR,
            compared to variant 1. Variants 1, 2, and 4-9 all encode the same
            isoform (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803615.214480.1,
                                           SRR1660803.138143.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2142363, SAMEA2142853
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000446702.7/ ENSP00000407822.2
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-337               BC113118.1         2-338
            338-467             DB170583.1         449-578
            468-2338            BC113118.1         469-2339
            2339-2339           AB003592.1         2427-2427
            2340-3342           BC113118.1         2341-3343
            3343-3458           CN364480.1         232-347
            3459-3481           AC034192.5         1-23                c
            3482-4065           AC026214.4         32148-32731
FEATURES             Location/Qualifiers
     source          1..4065
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3p26.3"
     gene            1..4065
                     /gene="CNTN6"
                     /gene_synonym="NB3"
                     /note="contactin 6"
                     /db_xref="GeneID:27255"
                     /db_xref="HGNC:HGNC:2176"
                     /db_xref="MIM:607220"
     exon            1..97
                     /gene="CNTN6"
                     /gene_synonym="NB3"
                     /inference="alignment:Splign:2.1.0"
     exon            98..234
                     /gene="CNTN6"
                     /gene_synonym="NB3"
                     /inference="alignment:Splign:2.1.0"
     CDS             180..3266
                     /gene="CNTN6"
                     /gene_synonym="NB3"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 2; neural adhesion molecule; neural recognition
                     molecule NB-3"
                     /codon_start=1
                     /product="contactin-6 isoform 1 precursor"
                     /protein_id="NP_001276009.1"
                     /db_xref="CCDS:CCDS2557.1"
                     /db_xref="GeneID:27255"
                     /db_xref="HGNC:HGNC:2176"
                     /db_xref="MIM:607220"
                     /translation="MRLLWKLVILLPLINSSAGDGLLSRPIFTQEPHDVIFPLDLSKS
                     EVILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLAINSPHTDQDIGMYQCLA
                     TNLLGTILSRKAKLQFAYIEDFETKTRSTVSVREGQGVVLLCGPPPHFGDLSYAWTFN
                     DNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQRT
                     DGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISWRRLDGSPLPGKVKYS
                     KSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWEQKIQNTHLSIYDN
                     LLWECKASGKPNPWYTWLKNGERLNPEERIQIENGTLIITMLNVSDSGVYQCAAENKY
                     QIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKRGTETL
                     RQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSK
                     MDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRN
                     IQLHHSGKYLCTVQTTLESLSAVADIIVRGPPGPPEDVQVEDISSTTSQLSWRAGPDN
                     NSPIQIFTIQTRTPFSVGWQAVATVPEILNGKTYNATVVGLSPWVEYEFRVVAGNSIG
                     IGEPSEPSELLRTKASVPVVAPVNIHGGGGSRSELVITWESIPEELQNGEGFGYIIMF
                     RPVGSTTWSKEKVSSVESSRFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTVTIVYSG
                     EDEPQLAPRGTSLQSFSASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKESMIGKIR
                     VSGNVTTKNITGLKANTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPPANIAWKL
                     TNSKLCLNWEHVKTMENESEVLGYKILYRQNRQSKTHILETNNTSAELLVPFEEDYLI
                     EIRTVSDGGDGSSSEEIRIPKMSSLSSRGIQFLEPSTHFLSIVIVIFHCFAIQPLI"
     exon            235..361
                     /gene="CNTN6"
                     /gene_synonym="NB3"
                     /inference="alignment:Splign:2.1.0"
     exon            362..537
                     /gene="CNTN6"
                     /gene_synonym="NB3"
                     /inference="alignment:Splign:2.1.0"
     exon            538..633
                     /gene="CNTN6"
                     /gene_synonym="NB3"
                     /inference="alignment:Splign:2.1.0"
     exon            634..837
                     /gene="CNTN6"
                     /gene_synonym="NB3"
                     /inference="alignment:Splign:2.1.0"
     exon            838..940
                     /gene="CNTN6"
                     /gene_synonym="NB3"
                     /inference="alignment:Splign:2.1.0"
     exon            941..1125
                     /gene="CNTN6"
                     /gene_synonym="NB3"
                     /inference="alignment:Splign:2.1.0"
     exon            1126..1262
                     /gene="CNTN6"
                     /gene_synonym="NB3"
                     /inference="alignment:Splign:2.1.0"
     exon            1263..1392
                     /gene="CNTN6"
                     /gene_synonym="NB3"
                     /inference="alignment:Splign:2.1.0"
     exon            1393..1543
                     /gene="CNTN6"
                     /gene_synonym="NB3"
                     /inference="alignment:Splign:2.1.0"
     exon            1544..1671
                     /gene="CNTN6"
                     /gene_synonym="NB3"
                     /inference="alignment:Splign:2.1.0"
     exon            1672..1847
                     /gene="CNTN6"
                     /gene_synonym="NB3"
                     /inference="alignment:Splign:2.1.0"
     exon            1848..1965
                     /gene="CNTN6"
                     /gene_synonym="NB3"
                     /inference="alignment:Splign:2.1.0"
     exon            1966..2124
                     /gene="CNTN6"
                     /gene_synonym="NB3"
                     /inference="alignment:Splign:2.1.0"
     exon            2125..2274
                     /gene="CNTN6"
                     /gene_synonym="NB3"
                     /inference="alignment:Splign:2.1.0"
     exon            2275..2345
                     /gene="CNTN6"
                     /gene_synonym="NB3"
                     /inference="alignment:Splign:2.1.0"
     exon            2346..2580
                     /gene="CNTN6"
                     /gene_synonym="NB3"
                     /inference="alignment:Splign:2.1.0"
     exon            2581..2696
                     /gene="CNTN6"
                     /gene_synonym="NB3"
                     /inference="alignment:Splign:2.1.0"
     exon            2697..2883
                     /gene="CNTN6"
                     /gene_synonym="NB3"
                     /inference="alignment:Splign:2.1.0"
     exon            2884..2996
                     /gene="CNTN6"
                     /gene_synonym="NB3"
                     /inference="alignment:Splign:2.1.0"
     exon            2997..3165
                     /gene="CNTN6"
                     /gene_synonym="NB3"
                     /inference="alignment:Splign:2.1.0"
     exon            3166..4065
                     /gene="CNTN6"
                     /gene_synonym="NB3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4043..4048
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CNTN6"
                     /gene_synonym="NB3"
                     /note="hexamer: AATAAA"
     polyA_site      4065
                     /gene="CNTN6"
                     /gene_synonym="NB3"
                     /note="major polyA site"
ORIGIN      
        1 atacggcttg gttctgcctg gacgcacagc atgcctggct gagagcttga aacagagttc
       61 tgcagaaaaa ctgtaaagat cccgagacat ttccctgact cttgagatac tgactggaag
      121 atagactgtt ttgttccacc tgattgtatg ggagaaattt ttgaccttag aaagtggaaa
      181 tgaggttgct atggaaactg gtaattctgc tgccactcat aaactcttct gcaggtgatg
      241 gtcttttaag ccgtcctatt tttactcagg agccacatga tgtcattttt cctttggatt
      301 tatcaaaatc tgaggtcatc ctgaattgtg ctgctaatgg ttacccttcg cctcattata
      361 ggtggaagca aaatggcaca gacattgatt ttactatgag ttatcactac aggttggatg
      421 gaggcagtct tgcaatcaat agcccccaca cagatcaaga tattggcatg taccagtgcc
      481 tggccaccaa tcttctgggg acaattctga gtcggaaggc aaagctccaa tttgcatata
      541 ttgaagactt tgaaactaaa acaagaagca cagtatctgt ccgagaaggt caaggtgtgg
      601 tgcttctctg tggcccaccg ccacattttg gagatttatc ttatgcatgg accttcaatg
      661 ataacccctt atacgtccaa gaggacaata ggcgatttgt atctcaagag acgggaaact
      721 tgtacattgc caaagtggaa ccatcagatg tgggcaacta cacttgcttt ataactaaca
      781 aagaggccca gagaagtgtt caaggtccac ccactccatt agtgcagcgc actgatggtg
      841 tgatggggga atatgaacca aagattgaag tgcgttttcc tgaaactata caagctgcaa
      901 aggattcatc tgtaaaactg gaatgttttg cccttggaaa tccagtcccc gatattagtt
      961 ggagaaggtt ggacgggagc ccgttgccag ggaaagtcaa gtacagcaaa tcccaagcta
     1021 tccttgaaat cccgaacttc caacaagaag atgaaggctt ttatgagtgc attgcaagca
     1081 accttcgagg aagaaacctt gcaaagggtc aactcatttt ttatgctcct ccagaatggg
     1141 aacagaaaat ccaaaataca cacctctcta tctatgacaa cttgctctgg gaatgtaaag
     1201 ctagtggaaa gccaaaccct tggtatacat ggttaaaaaa tggtgaacga ctcaacccag
     1261 aggagagaat tcaaatagaa aatgggacac tcatcataac gatgctgaat gtgtcagatt
     1321 ctggtgtgta ccaatgtgct gcagaaaaca aatatcagat aatttatgca aatgctgaat
     1381 tgagagtttt agcctcagct ccagatttct ccaaaagtcc agttaaaaaa aagtcttttg
     1441 ttcaagttgg tggggatatt gttatcggat gcaaaccaaa tgcttttccc agggcagcta
     1501 tctcttggaa aagaggaacg gagaccctta gacaaagcaa aagaatattt ctcttggagg
     1561 atggcagcct caagatatat aatattacca ggtcagatgc tggatcatat acatgcatag
     1621 ccacaaatca gtttggcact gcaaagaaca ctggcagcct cattgtaaaa gagagaactg
     1681 tcattaccgt cccaccttcc aaaatggatg ttacagttgg cgagagtata gtgctaccat
     1741 gccaggtgtc ccatgacccc tccattgaag tggtatttgt atggtttttc aatggagatg
     1801 tcatagactt aaaaaaagga gtggctcatt ttgaaaggat tggaggagaa tctgttgggg
     1861 atttgatgat aaggaatatt cagttacatc attcaggaaa atatctctgc acagtacaaa
     1921 caaccctaga aagtttatct gcagtagccg atatcattgt tagaggtcca ccaggtcctc
     1981 ctgaggatgt gcaagtggaa gacatttcca gtactacttc tcaactaagt tggagagcag
     2041 gcccagataa taacagtccc attcaaatat ttactattca gactcggaca ccattttctg
     2101 tgggttggca ggctgttgct acagttccag aaattctcaa tggtaagaca tacaatgcaa
     2161 cagtggttgg tttgagtcct tgggtggaat atgaatttcg tgttgttgcc ggcaacagca
     2221 ttgggattgg agaaccaagt gaaccatcag aattgttaag aactaaagca tcagtccctg
     2281 ttgtggcacc agtaaacatc catggaggtg gaggaagtcg gtctgaactc gtcattacgt
     2341 gggagtcaat tccagaagaa ctgcagaatg gggagggatt tggatatatc atcatgttcc
     2401 ggccagtggg ctcgacaacc tggtccaagg agaaagtgtc atctgtggaa tcatcaaggt
     2461 ttgtctacag aaatgaaagc atcatcccac tgtctccctt tgaagtcaaa gtgggtgtgt
     2521 ataataatga aggagaagga tccctgagta ctgtgaccat tgtctactct ggggaagatg
     2581 aacctcaact ggccccaagg ggaacttctc tccagagttt ttctgcttct gaaatggagg
     2641 tttcatggaa tgctattgcc tggaatagaa acactggaag agtgctgggc tatgaggtct
     2701 tatactggac agatgactcc aaagaatcca tgataggtaa aattagagtc agtggaaatg
     2761 tcacaaccaa aaacatcacg gggctgaaag ctaataccat ctactttgct tccgtaagag
     2821 cttacaacac tgctgggaca gggccctcaa gccccccagt caatgttacc accaaaaagt
     2881 ctcctccaag ccaaccacca gcaaacattg cctggaagct gacaaactct aaattatgct
     2941 tgaactggga gcatgtaaaa accatggaaa atgagtctga agttttgggg tacaagattc
     3001 tgtaccggca aaacagacag agtaaaactc atattttgga aacaaacaat acatcagctg
     3061 agcttctggt tccatttgaa gaagactact taattgaaat aagaacagtc agtgatggtg
     3121 gagatggaag cagcagtgag gaaattagga ttccaaaaat gtcaagtttg agttccagag
     3181 gaattcaatt cttagaacct agcacccatt ttctttccat tgtcattgtg atttttcact
     3241 gttttgctat tcagccactt atctgatgaa taaaaccata aatctttgag agttttttga
     3301 aagcaaatca ttctgtatat atgctctcca gcctctgaca caagatgcgt tcttaataca
     3361 gacttgtttg caaagaaaaa aaaaagtata ttattaaaat cctgtaaata tctatggtat
     3421 attaataaaa caattttaaa cacttttgaa ttttaaaatc cgcacatgat tacatgaatt
     3481 cctaggtgcc acattaacct ggggagttgt aactgctgtg tcttttaagt tacttatatg
     3541 gagaaaataa ataactcccc tcaatgatgc tgatgatgaa tacaaacttg gctcctagtt
     3601 accataactc acatgtacat ttttatgtat tccagacaat cacttcagta tttaaaattt
     3661 ccaccctact tcaaaataaa atacaattat ttgtttatag ttgggattct ttaaaaatac
     3721 aaactattcc aaagcatggg gtgcttttat ctctgaatca agttggaata agaaatcttt
     3781 ttactcaaga atatttcaat atacatgatg ttcttctcag cccacttttc agaagattca
     3841 gtcacaataa aggcagaaaa agtattttat ggcaaagaaa aataaatgat gggaaatgag
     3901 cacccaccta aaataatctt ctaacaactc tggtatatat taagcaattg ctcatggcaa
     3961 agttgaacat ttgaactgct gcatgaacaa atctcaggta attatgacaa gttgattgca
     4021 atgtatgtgg ccttattttt ataataaaac aatgtggaaa cagaa
//
