LOCUS       XM_017000261            5702 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens cannabinoid receptor 2 (CNR2), transcript
            variant X1, mRNA.
ACCESSION   XM_017000261
VERSION     XM_017000261.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017000261.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5702
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..5702
                     /gene="CNR2"
                     /gene_synonym="CB-2; CB2; CX5"
                     /note="cannabinoid receptor 2; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 7
                     mRNAs, 1 EST, 42 long SRA reads, 9 Proteins, and 89%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 3 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:1269"
                     /db_xref="HGNC:HGNC:2160"
                     /db_xref="MIM:605051"
     CDS             600..1682
                     /gene="CNR2"
                     /gene_synonym="CB-2; CB2; CX5"
                     /codon_start=1
                     /product="cannabinoid receptor 2 isoform X1"
                     /protein_id="XP_016855750.1"
                     /db_xref="GeneID:1269"
                     /db_xref="HGNC:HGNC:2160"
                     /db_xref="MIM:605051"
                     /translation="MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLG
                     LLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDS
                     KAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVL
                     SALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQ
                     HVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQ
                     VKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPR
                     SSVTETEADGKITPWPDSRDLDLSDC"
ORIGIN      
        1 ctgtttcggc ctcccaaagt gctaggatta caagcatgag ctaccacgcc cggcctaaca
       61 ctgtttttaa gattcatcat tgttggcacg ttttcaccac tttgtggtat tccttcgtat
      121 ggctgtatta caacttattt atccattttc cagttgatgg acatttagaa ttgttcttct
      181 atttcaaaaa tgccaaagag aacattcttg tacatgcctc cctggacgca cctgcaggag
      241 ttcctccaga acgtattccc gggactgcaa ttgatgtatc gtcaacttca ccagattttg
      301 ccaagctgct cttcaaagtg tctgtgtcaa cttacacccc catcgcaatg agagttcttt
      361 tggctccacg ccttctccag cactcagtat tgtcagcctt acttttttac cgatctgatg
      421 ggagtgaaac acatttctct gtctactatt gaggtctcat tctgtcaccc acactggagt
      481 gtggtggcac aatcatagat cactgcacac tggaccacct gggctgaagt aatcctttga
      541 cctcagcctc ccagcaaagc cttctagaca agctcagtgg aatctgaagg gcccacccca
      601 tggaggaatg ctgggtgaca gagatagcca atggctccaa ggatggcttg gattccaacc
      661 ctatgaagga ttacatgatc ctgagtggtc cccagaagac agctgttgct gtgttgtgca
      721 ctcttctggg cctgctaagt gccctggaga acgtggctgt gctctatctg atcctgtcct
      781 cccaccaact ccgccggaag ccctcatacc tgttcattgg cagcttggct ggggctgact
      841 tcctggccag tgtggtcttt gcatgcagct ttgtgaattt ccatgttttc catggtgtgg
      901 attccaaggc tgtcttcctg ctgaagattg gcagcgtgac tatgaccttc acagcctctg
      961 tgggtagcct cctgctgacc gccattgacc gatacctctg cctgcgctat ccaccttcct
     1021 acaaagctct gctcacccgt ggaagggcac tggtgaccct gggcatcatg tgggtcctct
     1081 cagcactagt ctcctacctg cccctcatgg gatggacttg ctgtcccagg ccctgctctg
     1141 agcttttccc actgatcccc aatgactacc tgctgagctg gctcctgttc atcgccttcc
     1201 tcttttccgg aatcatctac acctatgggc atgttctctg gaaggcccat cagcatgtgg
     1261 ccagcttgtc tggccaccag gacaggcagg tgccaggaat ggcccgaatg aggctggatg
     1321 tgaggttggc caagacccta gggctagtgt tggctgtgct cctcatctgt tggttcccag
     1381 tgctggccct catggcccac agcctggcca ctacgctcag tgaccaggtc aagaaggcct
     1441 ttgctttctg ctccatgctg tgcctcatca actccatggt caaccctgtc atctatgctc
     1501 tacggagtgg agagatccgc tcctctgccc atcactgcct ggctcactgg aagaagtgtg
     1561 tgaggggcct tgggtcagag gcaaaagaag aagccccgag atcctcagtc accgagacag
     1621 aggctgatgg gaaaatcact ccgtggccag attccagaga tctagacctc tctgattgct
     1681 gatgaggcct cttcccaatt taaacaactc aagtcagaaa tcagttcact ccctggaaga
     1741 gagagagggg tcttggcact ctcttcttac ttaaaccagt cccagacacc tagacacgga
     1801 cccctttttg ctgatgagtg ttgggactga ctcctggaag acagcctggc cttgcccacc
     1861 tgcacacagt ctgttggata ggtagggcca cgaggagtag ccaggtaggc gagacacaaa
     1921 aggcctggga cagggtcagt acaagtcagg tcaggcttca tgcctgcatc ctccagagac
     1981 cacaggagcc aaagcgagcc tccaggccca gcaatgaggg acttgggaga aatctgagaa
     2041 gaatgggttg ttctcttggg aagtcagggt atcagatggg atggacatcc aggtcttctc
     2101 tctgcctaat tgtcaaggcc tccttggctc tggagctatg aaaggcccca ctttcaagtc
     2161 acccttgcca ctgaggaccg aggactatgc tatgatgagg attaaggtgt tgacttgcct
     2221 ctttcagaga taaatgacaa gccttcagtt tggggcatcc tgttgtttgg gcgaggaccc
     2281 tctctgatat tctgataatc cccacctgta acctcaggtc cctggaaata cagaggaggc
     2341 tgggatcgcc tgagacacaa aaatctttgg agaattttct tgaccctctg aagtccttcc
     2401 agcagcagtc ctggtggtgc tgctggaagc aggcaatgtc ctagtctaac ctaactcgaa
     2461 gaaaaaaagg aagatattca caaagattgt ataaatctcc aaactgttcc cctatctgcc
     2521 cccaattcag ctcccttgcc tcctccacac ccctattaca tataataagc agagcaagtg
     2581 ggaggagggg aaatgtcctt cctatatgcc aggtatgggg ctgacatttc agtctattga
     2641 ccccagctag aatatagctc catgatttta aagatctcag gggccaggca tggtagctca
     2701 tgcctgtaat cccagcactt tgggaggcca aggcaggtgg atcacctgag gtcaggagtt
     2761 tgagaccagc ctgaccaata tggtgaaacc ctgtctctac taaaaataca aaaattagca
     2821 gggcatggtg gcaggcacct gtagtcccag ctactcggga ggctgagaca ggagaattgc
     2881 ttgaaccctg gaggcagagg ttgcagtgag ccgagattgc accactgcac tccagcctgg
     2941 gtgacagagc aagactgtct caaaaaaata aaataaaata gatcccaggg tactcatttt
     3001 tcatatgagg gaggctgggt tcctcccaga ggagcctaaa acagccaaca agagaaattg
     3061 ttggcggcag gaagattgca gaggaattct aatgcaatta tttgggacct caaatggaat
     3121 aaaatgaaag atattggtta aacatgtctt cgtttaatac tttcaagaca aaatatccac
     3181 tagctattca cttattcatt catctcataa acatgagcca ggctctgtgc agggtcctga
     3241 gtacccagcc ataaatgaga ctgtgcccct gtctcatggg gcttacagtc tatatcctgc
     3301 ttgcaagaca gccaataagt caataaagaa gataattaca ggcagtacaa caaaggaaat
     3361 atgcaggttc atgtcatgta atagggatta attgagttaa ctcaataaac ggtaggatag
     3421 acctaccatg tgccggctca cttttattga gcctttacta tgtgccaggc agggggctaa
     3481 gtgtttttaa atgccttatt tcacttcatg tttcccaaca acctaataag aaggtcttag
     3541 ttatcttcat tttacagatg tggcaacctc aaagatgcaa agtcacttgt ctaaggtcac
     3601 cctgctaagt accagagctg aggtctccaa cctagttctg tttgacttca aagcctgccc
     3661 tcttaaccac taaccttttg tcctagttca gtcaaattct gcttgattat tgctcattag
     3721 ggataatatt agctatctgt agcatcagat tgctgcaaag ttaactcatc gtagattctc
     3781 aatatactcc attttattaa atggccccgt attaatctcc tgtaataaat ttcacaaatc
     3841 cagtggctta tcaacagaaa tttactgtct cataattctg gaggccagaa gtcaaaatca
     3901 agatgtggta gggccctgct ccctccaaaa gtttaagggg agaattattc cttgactctt
     3961 tcaacttctg gcagtccctg tcattccttg gcttgtggaa acatcactcc tacctctgac
     4021 tctgtcttca tatggcattt cctctgtgtc tcttggtgtc tttttttttt tttttttttt
     4081 ttttgagacg gaatctcatt ctgttgtcca ggcaggagtg cagtgacatg atcttggctc
     4141 actgcaacct ccacctctca ggttcaagtg attctcctgc ctcagcctcc caaatagctg
     4201 ggactacagg cacccgccac cacactcagc taatttttgt atttttagta gagatggggt
     4261 ttcaccatct tgcccaggct ggtcttgaac tcctgacctc aagtgatccg cccaccttgg
     4321 cctcctaaat tgctgggatt acagacgtga gccaccatac ccggcctggt gtctttttta
     4381 aagaatatca gtcactggat ttgggcccac cctaatccta atagtatgac ttcatcttaa
     4441 tttaaccaat tatatctgta gagaccctgt ttccaaataa ggtcacattc acagattcca
     4501 ggtggacaag aagtttaggc ggacactatt caactcagta cagacccagg aacaaagtcc
     4561 acccactggg ctgtgttgag tggcagtcac tagtttatcc tccctcaaca agatgagctc
     4621 caggttgacc tctgcatccc cagtgctcag tcaggaccca gcagagcatc tgaagggatc
     4681 tggtcaatat gtgtggaact gaactgtttc tgaaaagctc tgacgtatgt tttggaaaat
     4741 caaatcttgt tttaatccag acaccaatct ttttgtaagg caaacaagta gcataaatgt
     4801 ttaaaagtga atttgcatgt ttatatactg tcattcctta aagttgaagc atgcctttct
     4861 ttattcatcg gtggaatcct ttctcatttt ggcaaagaaa atgcccaagt gcctggcaca
     4921 aacaagcact gagtaaatac ttcttgaatg aataaaacta gattctaaaa atcatttgat
     4981 caaacgcaac tccacacttt ctacttctct tcttttagaa ccacactgta tttctgcttt
     5041 tttttttttt tttttttttt ttgacataga atctcactct gtcacccagg ttggagtgca
     5101 gtggcatgca atcttggctc actgcaacct ctgcctcctg ggttcaagca gttctcctgc
     5161 cttagcctcc catgtagctg ggattacagg tacccgccac catgcccagc taatttttgt
     5221 attgttagta gagatggaat ttcaccatat tggccaggct ggtcttgaac tcctgacttc
     5281 aagtgatcca cccaccttag cctcccaaag tgctaggatt acaggtgtga gccaccactc
     5341 ccagccccta tgtctgcttt aagtggagaa gcagagctta tgagggagga gaacaagggt
     5401 gcaaaaggga cctagatatc actgagaact gcccttgttg tttggttgag gaaatgggcc
     5461 cagacagtgg acaagacttg ctcagggaga caaacgagat ggtgtccagt gcaacaaacc
     5521 taggtttcct aacttccagt tctgtccact ctacatcagt gcctctcacc tgtccctgca
     5581 ggttcacatt ttggttatgt ggataaggag aaataaattg aagatcacaa tgtcccattt
     5641 tatcttcccc aagacaagct ctgtaacatt aaagaccact atgcaaaccg attactagaa
     5701 aa
//
