LOCUS       NM_013354               6890 bp    mRNA    linear   PRI 29-OCT-2024
DEFINITION  Homo sapiens CCR4-NOT transcription complex subunit 7 (CNOT7),
            transcript variant 1, mRNA.
ACCESSION   NM_013354
VERSION     NM_013354.7
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6890)
  AUTHORS   Li,J., Wen,W., Li,J., Liu,T., Sun,J. and Chen,H.
  TITLE     CNOT7 regulates lipid deposition in nonalcoholic fatty liver
            disease
  JOURNAL   Biochem Biophys Res Commun 721, 150003 (2024)
   PUBMED   38772212
  REMARK    GeneRIF: CNOT7 regulates lipid deposition in nonalcoholic fatty
            liver disease.
REFERENCE   2  (bases 1 to 6890)
  AUTHORS   Chen,Y., Khazina,E., Izaurralde,E. and Weichenrieder,O.
  TITLE     Crystal structure and functional properties of the human CCR4-CAF1
            deadenylase complex
  JOURNAL   Nucleic Acids Res 49 (11), 6489-6510 (2021)
   PUBMED   34038562
  REMARK    GeneRIF: Crystal structure and functional properties of the human
            CCR4-CAF1 deadenylase complex.
REFERENCE   3  (bases 1 to 6890)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   4  (bases 1 to 6890)
  AUTHORS   Ramanan,V.K., Lesnick,T.G., Przybelski,S.A., Heckman,M.G.,
            Knopman,D.S., Graff-Radford,J., Lowe,V.J., Machulda,M.M.,
            Mielke,M.M., Jack,C.R. Jr., Petersen,R.C., Ross,O.A. and Vemuri,P.
  CONSRTM   Alzheimer's Disease Neuroimaging Initiative (ADNI)
  TITLE     Coping with brain amyloid: genetic heterogeneity and cognitive
            resilience to Alzheimer's pathophysiology
  JOURNAL   Acta Neuropathol Commun 9 (1), 48 (2021)
   PUBMED   33757599
  REMARK    GeneRIF: Coping with brain amyloid: genetic heterogeneity and
            cognitive resilience to Alzheimer's pathophysiology.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 6890)
  AUTHORS   Chapat,C., Kolytcheff,C., Le Romancer,M., Auboeuf,D., De La
            Grange,P., Chettab,K., Sentis,S. and Corbo,L.
  TITLE     hCAF1/CNOT7 regulates interferon signalling by targeting STAT1
  JOURNAL   EMBO J 32 (5), 688-700 (2013)
   PUBMED   23386060
  REMARK    GeneRIF: CNOT7 is an antimicrobial protein and a regulator of the
            innate immune response.
REFERENCE   6  (bases 1 to 6890)
  AUTHORS   Prevot,D., Morel,A.P., Voeltzel,T., Rostan,M.C., Rimokh,R.,
            Magaud,J.P. and Corbo,L.
  TITLE     Relationships of the antiproliferative proteins BTG1 and BTG2 with
            CAF1, the human homolog of a component of the yeast CCR4
            transcriptional complex: involvement in estrogen receptor alpha
            signaling pathway
  JOURNAL   J Biol Chem 276 (13), 9640-9648 (2001)
   PUBMED   11136725
REFERENCE   7  (bases 1 to 6890)
  AUTHORS   Dupressoir,A., Morel,A.P., Barbot,W., Loireau,M.P., Corbo,L. and
            Heidmann,T.
  TITLE     Identification of four families of yCCR4- and Mg2+-dependent
            endonuclease-related proteins in higher eukaryotes, and
            characterization of orthologs of yCCR4 with a conserved
            leucine-rich repeat essential for hCAF1/hPOP2 binding
  JOURNAL   BMC Genomics 2, 9 (2001)
   PUBMED   11747467
REFERENCE   8  (bases 1 to 6890)
  AUTHORS   Albert,T.K., Lemaire,M., van Berkum,N.L., Gentz,R., Collart,M.A.
            and Timmers,H.T.
  TITLE     Isolation and characterization of human orthologs of yeast CCR4-NOT
            complex subunits
  JOURNAL   Nucleic Acids Res 28 (3), 809-817 (2000)
   PUBMED   10637334
REFERENCE   9  (bases 1 to 6890)
  AUTHORS   Bogdan,J.A., Adams-Burton,C., Pedicord,D.L., Sukovich,D.A.,
            Benfield,P.A., Corjay,M.H., Stoltenborg,J.K. and Dicker,I.B.
  TITLE     Human carbon catabolite repressor protein (CCR4)-associative factor
            1: cloning, expression and characterization of its interaction with
            the B-cell translocation protein BTG1
  JOURNAL   Biochem J 336 (Pt 2) (Pt 2), 471-481 (1998)
   PUBMED   9820826
REFERENCE   10 (bases 1 to 6890)
  AUTHORS   Draper,M.P., Salvadore,C. and Denis,C.L.
  TITLE     Identification of a mouse protein whose homolog in Saccharomyces
            cerevisiae is a component of the CCR4 transcriptional regulatory
            complex
  JOURNAL   Mol Cell Biol 15 (7), 3487-3495 (1995)
   PUBMED   7791755
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from DA752620.1, BC070187.1,
            BC007315.2 and AC091050.3.
            
            On Nov 22, 2018 this sequence version replaced NM_013354.6.
            
            Summary: The protein encoded by this gene binds to an
            anti-proliferative protein, B-cell translocation protein 1, which
            negatively regulates cell proliferation. Binding of the two
            proteins, which is driven by phosphorylation of the
            anti-proliferative protein, causes signaling events in cell
            division that lead to changes in cell proliferation associated with
            cell-cell contact. The encoded protein downregulates the innate
            immune response and therefore provides a therapeutic target for
            enhancing its antimicrobial activity against foreign agents.
            Alternative splicing of this gene results in multiple transcript
            variants. Related pseudogenes have been identified on chromosomes 1
            and X. [provided by RefSeq, Apr 2016].
            
            Transcript Variant: This variant (1) encodes isoform 1. Variants 1,
            6, 7 and 8 all encode isoform 1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803612.49781.1,
                                           SRR1803617.140639.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN03267763 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match                 :: ENST00000361272.9/
                                                  ENSP00000355279.4
            Protein has antimicrobial activity :: PMID: 23386060
            RefSeq Select criteria             :: based on conservation,
                                                  expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2                 DA752620.1         53-54
            3-1328              BC070187.1         1-1326
            1329-2267           BC007315.2         1195-2133
            2268-2628           BC007315.2         2135-2495
            2629-6890           AC091050.3         22774-27035
FEATURES             Location/Qualifiers
     source          1..6890
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="8"
                     /map="8p22"
     gene            1..6890
                     /gene="CNOT7"
                     /gene_synonym="CAF-1; CAF1; Caf1a; hCAF-1"
                     /note="CCR4-NOT transcription complex subunit 7"
                     /db_xref="GeneID:29883"
                     /db_xref="HGNC:HGNC:14101"
                     /db_xref="MIM:604913"
     exon            1..183
                     /gene="CNOT7"
                     /gene_synonym="CAF-1; CAF1; Caf1a; hCAF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            184..395
                     /gene="CNOT7"
                     /gene_synonym="CAF-1; CAF1; Caf1a; hCAF-1"
                     /inference="alignment:Splign:2.1.0"
     CDS             279..1136
                     /gene="CNOT7"
                     /gene_synonym="CAF-1; CAF1; Caf1a; hCAF-1"
                     /EC_number="3.1.13.4"
                     /note="isoform 1 is encoded by transcript variant 1;
                     carbon catabolite repressor protein (CCR4)-associative
                     factor 1; BTG1-binding factor 1; CCR4-associated factor 1"
                     /codon_start=1
                     /product="CCR4-NOT transcription complex subunit 7 isoform
                     1"
                     /protein_id="NP_037486.2"
                     /db_xref="CCDS:CCDS6000.2"
                     /db_xref="GeneID:29883"
                     /db_xref="HGNC:HGNC:14101"
                     /db_xref="MIM:604913"
                     /translation="MPAATVDHSQRICEVWACNLDEEMKKIRQVIRKYNYVAMDTEFP
                     GVVARPIGEFRSNADYQYQLLRCNVDLLKIIQLGLTFMNEQGEYPPGTSTWQFNFKFN
                     LTEDMYAQDSIELLTTSGIQFKKHEEEGIETQYFAELLMTSGVVLCEGVKWLSFHSGY
                     DFGYLIKILTNSNLPEEELDFFEILRLFFPVIYDVKYLMKSCKNLKGGLQEVAEQLEL
                     ERIGPQHQAGSDSLLTGMAFFKMREMFFEDHIDDAKYCGHLYGLGSGSSYVQNGTGNA
                     YEEEANKQS"
     exon            396..589
                     /gene="CNOT7"
                     /gene_synonym="CAF-1; CAF1; Caf1a; hCAF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            590..751
                     /gene="CNOT7"
                     /gene_synonym="CAF-1; CAF1; Caf1a; hCAF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            752..896
                     /gene="CNOT7"
                     /gene_synonym="CAF-1; CAF1; Caf1a; hCAF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            897..1007
                     /gene="CNOT7"
                     /gene_synonym="CAF-1; CAF1; Caf1a; hCAF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1008..6890
                     /gene="CNOT7"
                     /gene_synonym="CAF-1; CAF1; Caf1a; hCAF-1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2599..2604
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CNOT7"
                     /gene_synonym="CAF-1; CAF1; Caf1a; hCAF-1"
                     /note="hexamer: AATAAA"
     polyA_site      2628
                     /gene="CNOT7"
                     /gene_synonym="CAF-1; CAF1; Caf1a; hCAF-1"
                     /note="major polyA site"
     regulatory      6868..6873
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CNOT7"
                     /gene_synonym="CAF-1; CAF1; Caf1a; hCAF-1"
                     /note="hexamer: AATAAA"
     polyA_site      6890
                     /gene="CNOT7"
                     /gene_synonym="CAF-1; CAF1; Caf1a; hCAF-1"
ORIGIN      
        1 gtgcgaaaag cgacggcgca gcacggtgcg gcgcagctcc tgctcgcctt tcccttcgct
       61 gggcgagagg tgtctatggg gcacccgctg ccgccgccgc taccgccacc gccaccgcca
      121 ccgccgccga gtgctgtctc tatggcgagg aggaggagga ggagcgcgag ctcagcgaca
      181 caagtacata aataaaggat aaaatatttt atgaaacaaa tcttcaatca agtataacat
      241 tttgatgctt ggcatctaga ctcccttgtg ccctcactat gccagcggca actgtagatc
      301 atagccaaag aatttgtgaa gtttgggctt gcaacttgga tgaagagatg aagaaaattc
      361 gtcaagttat ccgaaaatat aattacgttg ctatggacac cgagtttcca ggtgtggttg
      421 caagacccat tggagaattc aggagcaatg ctgactatca ataccaacta ttgcggtgta
      481 atgtagactt gttaaagata attcagctag gactgacatt tatgaatgag caaggagaat
      541 accctccagg aacttcaact tggcagttta attttaaatt taatttgacg gaggacatgt
      601 atgcccagga ctctatagag ctactaacaa catctggtat ccagtttaaa aaacatgagg
      661 aggaaggaat tgaaacccag tactttgcag aacttcttat gacttctgga gtggtcctct
      721 gtgaaggggt caaatggttg tcatttcata gcggttacga ctttggctac ttaatcaaaa
      781 tcctaaccaa ctctaacttg cctgaagaag aacttgactt ctttgagatc cttcgattgt
      841 tttttcctgt catttatgat gtgaagtacc tcatgaagag ctgcaaaaat ctcaaaggtg
      901 gattacagga ggtggcagaa cagttagagc tggaacggat aggaccacaa catcaggcag
      961 gatctgattc attgctcaca ggaatggcct ttttcaaaat gagagaaatg ttctttgaag
     1021 atcatattga tgatgccaaa tattgtggtc atttgtatgg ccttggttct ggttcatcct
     1081 atgtacagaa tggcacaggg aatgcatatg aagaggaagc caacaagcag tcatgacatg
     1141 aaatagtcct tttattttta tttcgagcta cacacatgct tgtatatagg ttttatctct
     1201 ggttgaatcc ctcgaacaat agacagtacc tttccccccc ctttcatggc ccattttatt
     1261 gtctgccttt cagtactaag tatgaccgtt cctatctcag atcttaataa aaagaaaaaa
     1321 aaaaacgcat tcaggttaaa tttggcctta atttaatata cttgttagca agcgtgtgtg
     1381 acagagagtg gggaaagcta catcattgaa tattttgata aactttaccg acttgagttt
     1441 ggtttatttt tcccttttcc taaattaact agcactgact gtaatttatt tccctgtttc
     1501 acgtctctcc cttccattct gcaggagttt tagctatttg agatcgtgga ccatcagttt
     1561 tgcactttag agagtgtttc tgactctaaa cctgttttat cagaaaattt gttttttctt
     1621 gatcttagct ggaaaaatct gccaacttta cacagtattt acttggtttt gacccacaga
     1681 atatagcacg ttgtgcaaac tgtcgattca gcgaaactta aaaaagacaa gaaactactg
     1741 aggagcttag taactgctgt ttctgtacgt agtgtttaat cttccaagca catctagtgt
     1801 ctgtcagttt ctaattggca tgtgtaggct gctctgtgac tgaagaattt tcaaaccagc
     1861 tttacaccct tcaggaaaaa tcccttgtga ttggatgttt actatctgcc aggaaactgg
     1921 tactcaagat gttgaagcta cagttatttt atgatagcac acttcccttg atctgcttat
     1981 ttttattcca tcaccattta cccttttttt ttttttaaat tttgtagcca ttcttatgat
     2041 gctcttgatt tgttggttac acaaatcaat tttattaaaa atccaaagat aagtctttag
     2101 gtatattttg taccaaatta aattagaaga caaaaattgt gctttcatag ttgctacaaa
     2161 ggtaaataat ggagagattt ggtacaaaac aacaaaatat atatatattc tcatatatat
     2221 atatatagct gataaaatta cctgaggagt gtaatgctta tttttttgtg tatatctttg
     2281 caatctattt tatatatatt gacaaaagag actgtgaaat acttagccat gcagaatatg
     2341 tgaccagacc agagcatgtg taggaagact ttacggtaat cattaactct accccgaaat
     2401 gatggactac aagttataat gtgtgttacc tacacttcaa tcagtaatat tagcaaatct
     2461 ccaaatgtta gtcacattgg tttgtctccc ttgtacattc tttattcatg atattacagt
     2521 gctgtaactg ggtggtcctt tttaaacaaa acattatttg caaaacagag ggtattattt
     2581 gtttttaaag cttttgtaaa taaaggcttc aaaatgtttt cttataaatg ttgatgactg
     2641 gtgattttct tttggaaata cttatttggg ggatattgtt catttttatt tgggcaactc
     2701 aacagaattc agtaacttcc ttcattaacc ctagatgatt attagtccat taattgaaaa
     2761 atcagtctga gttttctgca tttcaagtgt tggcttattc ttgttcttta tgagtacctc
     2821 aactagctaa ttaaggactg acttctgttt ctcctttcca ggaatgcatt tattccgaag
     2881 gatatacttc acaaagtaaa tacatttggt ataactgtgg ctttttaaaa aatctaacac
     2941 aatgtagtaa gtttctaact ggcttctttt gtcttcgtta aaaaggaagt gaagcttctt
     3001 ttcgcttgtg atttgttagc tgagaaaact aatatttaaa ttctgttcaa ctatttgaga
     3061 aatcaatgct ggatttcaaa taggaatgat aaagattgcc tttttattag ccacatagtt
     3121 gctcaatctc ataacttgta tcatttctgg cttctgtccc taaaaagtat agataatccc
     3181 taacttactt tcgacttaat gatttttcaa ctttacagtg ggtgtattga gaggtaaccc
     3241 catcaaaagt ttaggagcgc cttaggacca aagatggggt tatagtttct actgaatgtg
     3301 tattgctttt gcaccattgc aaagtcaaaa tttataactt gaaccatcgt aaattggggg
     3361 actgtatgct gttgcctgca ttaaatgcat cttagtattt tttcagatgt aacctcattg
     3421 taggttgagc aaccgtatag tgtaactttt gtagaggaac attttgactt ttactgggtc
     3481 taagttttac ttttttattt tgttccagac agtctcaatg tttgtaaagt ctaggttcca
     3541 gatgtaagat atttggctga tattttagtg ttactgagcc attaattaat tacaggctca
     3601 tatattctgt taaatctact agagcaaggg ttgtcaaact atggcccgta gccagaatca
     3661 gcttgctgcc tgtttttgtg tggcccatga actgaaaatg gcttttaaat ggttgggaaa
     3721 aataatcaaa agattatttc ctgacatctg aaaattacat gaaattcaaa ttttagtgtc
     3781 tataagtttt tattggaatg cagccacact aatttacata ttatctatgg atactttttt
     3841 gctataatgg gaaagttgag tagctgctac agaacctgtg tatgtgtgtc ttgtttcaca
     3901 ttgccgcttg gcaagctaca gaatcatggt gatgcagata ttacctgaaa gcatttggaa
     3961 tgccctgtgt attgctagat ttattacttt ttctgctacc agttcatgcc ctgtatctca
     4021 gaacaagaaa agtacctttg aatgttacac tttcaaggca cattggaata tggactattt
     4081 tattatatgc tggtacattg tgtttataat gcagtgtcac cataactggt aaaagaatag
     4141 actgacagta tcagactaac atcacaatat tcccaactgg tgggaaagca acagtcagaa
     4201 gaattagaaa atttaaatga aacatcacag caaaatttca caaaagtaat aaaaatgagg
     4261 ctgcaaccaa aatgtttaca agtagcctat ttgttagcca agcaaagaaa accatttact
     4321 aatgctgaat tacatcgtgc ttgaagatag taaccaaccc aaagacatgt gtccagagaa
     4381 aattaagaca tcagcccttt gatgagaaca gtagtttgaa gaatgaggat tttggacaca
     4441 acatcaaatg acactgttaa ttctttgcct cttactagtc agtactgcct agctttattt
     4501 tttgagaaac cattgctgga tttgaagtga tcgaagaatt tgtatggaac tacaagtggg
     4561 aatattttca aaaaagttga taaacagtac aacctgaagt ggaatctact aagatgtgat
     4621 gcaaccgatg ctgggaaaaa tgcatgaagc agaaaaaaag tttatttggt caaattttaa
     4681 ggcttgtgaa aacgtaagtt gtttaaagcc tgtagttact cacttgatta ttcatcagca
     4741 ggtacttcac aggaaatatt ggtgttactg aactggtcaa cagttaactt catttgctct
     4801 tgtggactta accatcttca gttccatgat tttttttttt ttgtgagaaa cagaagctga
     4861 atatcctgat ttgatttgcc acacaggcgt tcaatggctt agcagtgcta aagatttatt
     4921 tttatttttt tgggctctgg gctgacattg aaatttttct gaatgagaaa aaccatcctc
     4981 aaccactgtt ttttaacact gagtaacttt ggaaattaac ttttgccaca gacttgaaaa
     5041 tgtttcttaa tgaatttgac ctgaaattac aaggtacaac aacataatat ggtaaattca
     5101 tttcaataaa aactaaaact taagattgtc aagctgcttt atatactttc tgtgctatga
     5161 gaagtcaaaa cagcgctgta ttgccaaatc catttttagt ggatatattt tcctgtagca
     5221 gttttttgga ccttgatgca gtgcaaagaa aatttttaaa ttttaaaagc atttaactgc
     5281 aattaaatgc ttttaaagtt tcctcttaat cttctgttgg aaatgaatca tcttgaatga
     5341 atgacatgct aaagggcaaa taccaaaaag atgaatccta caaatgcctt acaagtgatg
     5401 aatatgctta actaaaatca catgctcatg ggtggatgtg tcagtattta gcagtacctt
     5461 gacctgtttg tgtgaaaaga cattttcaaa gatgaaatac gtgaaatccc attacacatc
     5521 agcattaaca gattaacatt ttctatttat tccaatgagg ggataccaac tttcagccca
     5581 aattgagcaa aatgttacct cccgtcccct gccaaaaaat cccattattc ccattagtag
     5641 aactctatta ctaaaaaaag aaaaaaaaat tgtactcaat attttgagtt ttcaattttt
     5701 agaataaaaa tttggtgaaa agtttccttg agtacctaaa taatgtcctt cattttgtct
     5761 tagcttgcaa agcctctaat atttgctacc tgcccttttc aaaaaaaaaa aaaaaaaaaa
     5821 aaaaaaggct tgtccacctc tctactagaa gaaactcaag ggtctatgtc tgtcctgttt
     5881 gctatttcat ctgcattgcc aaatgcagtg gctcctctgg gtaggcaacc tgaggtggaa
     5941 tcaaattatg aatgcatatg ttatctcatg tctataaaat aaatgtgtta gaatttataa
     6001 ataaagggat aggaaaaatg ctgattattc tgtgtgtcgg tgctttgtag tgaaggccag
     6061 ttcacacatg ccatttgcta tgttggtgta atttatatga gagtttcttt tataacaacg
     6121 ttacctgtca tttatttttc tattaagaca ttatagaaac gtaggactgt acacatccaa
     6181 atcctgcaga attttcattt caggttttga aagttaaaaa aatgtcacca tagaatgaaa
     6241 attccaagaa aacaagattc atgtacatta tcactagaca atttccattt gttttaaaca
     6301 gttttctaca gcattagtta catttaacgt ttagtataaa agcaattgag caatttctct
     6361 ttagaagtcc atttcattgc tttgtagcca tagtctgtag gtgaatgaac aagctacatt
     6421 tctccagaat tactcatttt ctttttaaag ataaactggt caatactctc cttcctggta
     6481 tggaggaatt ttttgtatat gagaagcatt catgaatata atctgccctc ttgctttatt
     6541 gtcataggag gggaaattca ctgctttcac acccttctgt tttggctctt tctcccaaaa
     6601 gataagaatc tttatttagt atcataccaa gaaattggag ttcctttagc ttcagactat
     6661 catcatggct tccaaattgt taggaaatac aagtttgcaa gaccccaagg ggacttaata
     6721 ttttacatct tactagccat gtcataggtt ttaagtgctt ttaatgggga actgtttcac
     6781 tcatgccata tacctgtttt gtttttctaa aaaattaata ctgtaagttg tgagcaggtg
     6841 tcttgtatca ctgcgaaacc catgcataat aaaaacttgt tcttgagcta
//
