LOCUS       XM_005263914            4846 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens cyclin and CBS domain divalent metal cation
            transport mediator 4 (CNNM4), transcript variant X2, mRNA.
ACCESSION   XM_005263914
VERSION     XM_005263914.5
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000002.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_005263914.4.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4846
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
     gene            1..4846
                     /gene="CNNM4"
                     /gene_synonym="ACDP4"
                     /note="cyclin and CBS domain divalent metal cation
                     transport mediator 4; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 2 mRNAs, 30 ESTs, 312
                     long SRA reads, 9 Proteins, and 99% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     27 samples with support for all annotated introns"
                     /db_xref="GeneID:26504"
                     /db_xref="HGNC:HGNC:105"
                     /db_xref="MIM:607805"
     CDS             99..2489
                     /gene="CNNM4"
                     /gene_synonym="ACDP4"
                     /codon_start=1
                     /product="metal transporter CNNM4 isoform X2"
                     /protein_id="XP_005263971.1"
                     /db_xref="GeneID:26504"
                     /db_xref="HGNC:HGNC:105"
                     /db_xref="MIM:607805"
                     /translation="MAPVGGGGRPVGGPARGRLLLAAPVLLVLLWALGARGQGSPQQG
                     TIVGMRLASCNKSCGTNPDGIIFVSEGSTVNLRLYGYSLGNISSNLISFTEVDDAETL
                     HKSTSCLELTKDLVVQQLVNVSRGNTSGVLVVLTKFLRRSESMKLYALCTRAQPDGPW
                     LKWTDKDSLLFMVEEPGRFLPLWLHILLITVLLVLSGIFSGLNLGLMALDPMELRIVQ
                     NCGTEKERRYARKIEPIRRKGNYLLCSLLLGNVLVNTSLTILLDNLIGSGLMAVASST
                     IGIVIFGEILPQALCSRHGLAVGANTILLTKFFMLLTFPLSFPISKLLDFFLGQEIRT
                     VYNREKLMEMLKVTEPYNDLVKEELNMIQGALELRTKTVEDIMTQLQDCFMIRSDAIL
                     DFNTMSEIMESGYTRIPVFEDEQSNIVDILYVKDLAFVDPDDCTPLKTITRFYNHPVH
                     FVFHDTKLDAMLEEFKKGKSHLAIVQKVNNEGEGDPFYEVLGLVTLEDVIEEIIKSEI
                     LDESDMYTDNRSRKRVSEKNKRDFSAFKDADNELKVKISPQLLLAAHRFLATEVSQFS
                     PSLISEKILLRLLKYPDVIQELKFDEHNKYYARHYLYTRNKPADYFILILQGKVEVEA
                     GKENMKFETGAFSYYGTMALTSVPSVPSVQVGCPPGKRNSLLCWLTDRSPAHPTPLSR
                     SASLSYPDRTDVSTAATLAGSSNQFGSSVLGQYISDFSVRALVDLQYIKITRQQYQNG
                     LLASRMENSPQFPIDGCTTHMENLAEKSELPVVDETTTLLNERNSLLHKASHENAI"
ORIGIN      
        1 agttggctcg gcggcagcgg agcggccgga gctgcggtgc ggaccggggc cgcgcggcgt
       61 ggcgcgggga gcggcggcgg cggcagagcc agagcaacat ggcgccggtg ggcgggggcg
      121 ggcgcccggt cggcggaccg gcccgcgggc gcctcctcct ggcggcgccg gtgctgctgg
      181 tgctgctgtg ggcgctgggg gcccggggcc agggcagccc ccagcagggc acgatcgtgg
      241 gcatgaggct ggcgagctgc aacaagtcgt gtgggacgaa cccggatggc atcatcttcg
      301 tgtccgaggg cagcaccgtg aacctgaggc tgtacggcta cagcctgggc aacatctcca
      361 gcaacctgat ctccttcacc gaggtggacg atgccgagac cctccacaag tccaccagct
      421 gcctcgagct caccaaggac ctggtcgtcc agcagctggt caacgtgagc cgcgggaaca
      481 cgtccggcgt gctggtggtg ctcaccaagt tcctccggag gagcgagagc atgaagctgt
      541 atgcactgtg cacccgggcc cagcccgacg ggccctggct gaagtggacg gacaaggact
      601 cactgctctt catggtggag gagcctggga ggttcctgcc tctctggctg cacattctcc
      661 taattacggt gctgctggtg ctgtcgggca tattttctgg cctcaacctc gggcttatgg
      721 ccctggaccc catggagctg cgcatcgtgc agaactgtgg caccgagaag gagaggcgct
      781 atgcccgcaa gattgagccc atccggcgca agggcaacta ccttctctgc tcgttgctcc
      841 tagggaacgt gctggtcaac acctccctca caatccttct agacaacctc atcgggtccg
      901 gcctcatggc ggtggcctcc tccaccattg gcattgtcat ctttggggag atcctacctc
      961 aggccctgtg ctcccgacat gggctggctg tgggtgccaa caccatcctt ctcaccaaat
     1021 tctttatgct actcaccttc cccctcagtt ttcccattag caagctcctg gacttttttc
     1081 tgggccagga gattcgcact gtttacaacc gggagaagct gatggagatg ttgaaggtga
     1141 cggagcccta taatgacctc gtgaaagagg agctcaatat gatccagggt gccctggaac
     1201 tacggaccaa aactgtagag gatatcatga cccagctcca ggactgcttc atgatccgca
     1261 gcgatgccat cctggacttc aacaccatgt cggagataat ggaaagcggc tatactcgca
     1321 tcccggtgtt cgaagacgag cagtccaata ttgtagatat tctctacgtc aaagacttgg
     1381 cctttgtgga ccccgatgac tgcacccccc tcaagactat cactcgcttc tataaccacc
     1441 cggtgcactt tgtcttccat gacaccaagt tggatgccat gctggaggag ttcaagaagg
     1501 ggaagtccca cctggccatc gtgcagaagg taaacaacga gggtgagggt gaccccttct
     1561 acgaggtcct gggcctggtc accctggagg acgtgatcga ggagatcatc aagtcggaga
     1621 tcctggacga gtccgacatg tacactgaca accgaagccg gaagcgggtg tctgagaaga
     1681 acaagcgtga cttctctgcc ttcaaggatg cggacaatga gctcaaagtg aaaatctccc
     1741 cgcagctcct cctggccgct catcgcttcc tagccacaga ggtctctcag tttagcccct
     1801 ccctgatatc agagaagatc ctgctgcggc tactcaagta cccagatgtc attcaggaac
     1861 tcaagtttga cgagcacaat aagtactacg cccgccatta cctgtacacc cgaaataagc
     1921 cggccgacta cttcatcctc atcctgcagg ggaaggtgga ggtggaggca gggaaggaga
     1981 acatgaagtt tgagacgggc gccttctcct actatgggac tatggccctg acctcggtcc
     2041 cctccgtgcc ttcagtccag gtcgggtgtc cgcctggcaa gcggaactcc ctgctctgct
     2101 ggctcacaga ccgttcccca gcacacccca ccccactcag ccgctcagcc tccctcagtt
     2161 acccagaccg cacagacgtc tcaactgcag caaccttggc aggcagcagc aaccagtttg
     2221 gcagctctgt cctgggccag tacatctctg acttcagcgt ccgggcactc gtggacttgc
     2281 agtacatcaa gatcactcgg cagcagtacc agaacgggct gctggcttct cgcatggaga
     2341 acagccctca gtttcccata gacgggtgca ccacccacat ggagaacttg gccgagaagt
     2401 ctgagctgcc tgtggtggac gagaccacaa ctcttctcaa cgagcgtaac tccttgctgc
     2461 acaaagcctc ccacgagaat gccatctgac aggagggccc ggggccccct gcccaccctg
     2521 cgggggcctc cccagtgggc ccacatgaag agagggaacc tgttagtcca gaaaggatac
     2581 ggatagatag cctgtctgac tgaacagcca gatggccccc agcctatggg ggatctggcc
     2641 tctgccaggg acctctgagt agctctgagg tggcactgtc cagccctgga tagggggggc
     2701 agtgggccag ctaccgtaag caaaggctgt tttttactga gagaatttct aaagtaggct
     2761 catcactttt ttttaaatat cattttggga agggaagaca gggttaagga actttattta
     2821 aaaaaaaaat atttttttcc taaaaactat aaaagaggaa gggtttcttg tcccgggaag
     2881 caacggacat aatctgttcc cagccatggc cttccagctt gtgtccctga ttcagggagc
     2941 tctcccttcc tcctcctcct cctcctccgg aggtgggatc ccagagcctg ccagtggagg
     3001 cttatctgtt gggaggaaga cagctcttca cagaagcaaa gaacaaaatg gcatggagat
     3061 cagctgcctg agcacctgcg ctgtagctta tctgacaacg ctgaggccac gagctcctgg
     3121 gtagctgtga tcagggacat gataatctga gctatgcaga ggagcacatc tgttgtcaac
     3181 tgctgtaccc agaaatctag aactctgccg acagcctctc ctggtgagtc gggactcagc
     3241 tgaggacaca tccccaccct gcctcccatc tggccctttg gacaactggc cctttgtgac
     3301 agggctgact caagtgttag gcagggtctc aggcctttga ttgctcaccc ctgctcccca
     3361 ggccctgccc tcacttttac caaaggttct ccctcggcgg gagggcatct gtgttggagg
     3421 tgatttgtct gggttcttcc ttttggttcc agaaggaact gtcagtcatc agcatctgcg
     3481 ttgttagcag tcagtaccac ccccgcccca caatgacagt caaggctgac ttgttgactg
     3541 aagccttttt cccagacccc ttatttcgaa tccccaagct tcagtccctc ttgggggtgg
     3601 agacaagagg acatgtggga agccacggaa gcaggttctt tatgtcctct cctctgtggc
     3661 tggcaaggct cacctggcct tatccaccca cttatggaac ctcaggagag gagggctcct
     3721 cctaaaggca tgcagcttgc agcccctctt tctcacacgt gtgatcctag cgtgagaggt
     3781 catcctgccc ttgctgaagt tagtagtact gtactaagag ctctgccctc atgtgaattc
     3841 ctgccctggc gcctcttccc tggggctgaa tcaggccctg ctgcaaaact ccaggcttcc
     3901 cagggttggg gaggctgtgg gaccaaggtc catgttggtc cttccactgg gtgcagcagg
     3961 agctgggtcc cgagagcctg gcaggtgaaa ctctgcaggc cttccgcctg attattattt
     4021 attcactcct ttcctcaccc caagtgccct gctctccagg tgcctagagt atcctaactc
     4081 ttaggaccag ggattgtctt gcaccaagta tgcctacccc tggccagtct gaggtctcct
     4141 agccatagaa ctgactcctg gaagcctgga gagaaggtgg tgacacccat gggttctcaa
     4201 ctgtaaggaa aaaagacacc agacttttgt tccctagtgg gggaaagccc ttagtcttgt
     4261 acaggagcag cttgctccca agtccttttg gaagctggca gagctatatt cctgacagcc
     4321 ctgactgcca ggtagagcaa aagacattgg tgggggtatg tgaagcaaaa ggggcaggtg
     4381 cacacacctc cacagtgacc tctgtgcaca cggttaccac caactggctg gccctcctcc
     4441 tcttccctgg cccattgatc atcccttctc acagagggtc atcattattt ccaaatattg
     4501 tttgtctgat gacttcctct tcccagtgca atttttccct tcctatttca acctctggtt
     4561 cctgggatga gccataccct ggaactggcc cacccactgt gtcttccacg taagggagac
     4621 ctttgcaaag ggcatccaaa tgggtaggca ggtgacagcc gccgtattta ttttgcataa
     4681 tattttaatt tgtatatttt tgtgatttat tttggcgtta tgagtttgac tctcggggag
     4741 ttttgttgtt atgactcttg tgtcttttgt cacaaaacaa tgatatttgc taaacgatat
     4801 atggaattta tttttgattg gtaataaaaa atcaaatatg tataaa
//
