LOCUS       NM_001365709            1956 bp    mRNA    linear   PRI 02-APR-2024
DEFINITION  Homo sapiens cyclic nucleotide binding domain containing 2 (CNBD2),
            transcript variant 5, mRNA.
ACCESSION   NM_001365709 XM_005260295
VERSION     NM_001365709.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1956)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL109965.34 and AL359828.13.
            
            On Sep 12, 2018 this sequence version replaced XM_005260295.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA1968968,
                              SAMEA2148093 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000373973.7/ ENSP00000363084.3
            RefSeq Select criteria :: based on manual assertion, conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-224               AL109965.34        78720-78943
            225-362             AL109965.34        82759-82896
            363-416             AL109965.34        86079-86132
            417-580             AL109965.34        90589-90752
            581-737             AL109965.34        94112-94268
            738-889             AL109965.34        94757-94908
            890-1028            AL109965.34        97525-97663
            1029-1091           AL109965.34        105168-105230
            1092-1143           AL359828.13        103-154
            1144-1321           AL359828.13        13299-13476
            1322-1442           AL359828.13        16139-16259
            1443-1612           AL359828.13        28604-28773
            1613-1956           AL359828.13        35359-35702
FEATURES             Location/Qualifiers
     source          1..1956
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="20"
                     /map="20q11.23"
     gene            1..1956
                     /gene="CNBD2"
                     /gene_synonym="C20orf152; CNMPD1"
                     /note="cyclic nucleotide binding domain containing 2"
                     /db_xref="GeneID:140894"
                     /db_xref="HGNC:HGNC:16145"
     exon            1..224
                     /gene="CNBD2"
                     /gene_synonym="C20orf152; CNMPD1"
                     /inference="alignment:Splign:2.1.0"
     CDS             174..1904
                     /gene="CNBD2"
                     /gene_synonym="C20orf152; CNMPD1"
                     /note="isoform 4 is encoded by transcript variant 5;
                     cyclic nucleotide (cNMP) binding domain containing 1;
                     cyclic nucleotide-binding domain-containing protein 2"
                     /codon_start=1
                     /product="cyclic nucleotide-binding domain-containing
                     protein 2 isoform 4"
                     /protein_id="NP_001352638.1"
                     /db_xref="CCDS:CCDS93033.1"
                     /db_xref="GeneID:140894"
                     /db_xref="HGNC:HGNC:16145"
                     /translation="MRRHMVTYAWQLLKKELGLYQLAMDIIIMIRVCKMFRQGLRGFR
                     EYQIIETAHWKHPIFSFWDKKMQSRVTFDTMDFIAEEGHFPPKAIQIMQKKPSWRTED
                     EIQAVCNILQVLDSYRNYAEPLQLLLAKVMRFERFGRRRVIIKKGQKGNSFYFIYLGT
                     VAITKDEDGSSAFLDPHPKLLHKGSCFGEMDVLHASVRRSTIVCMEETEFLVVDREDF
                     FANKLDQEVQKDAQYRFEFFRKMELFASWSDEKLWQLVAMAKIERFSYGQLISKDFGE
                     SPFIMFISKGSCEVLRLLDLGASPSYRRWIWQHLELIDGRPLKTHLSEYSPMERFKEF
                     QIKSYPLQDFSSLKLPHLKKAWGLQGTSFSRKIRTSGDTLPKMLGPKIQSRPAQSIKC
                     AMINIKPGELPKEAAVGAYVKVHTVEQGEILGLHQAFLPEGECDTRPLILMSLGNELI
                     RIRKEIFYELIDNDDEMIKKLLKLNIAFPSDEDMCQKFLQQNSWNIFRKDLLQLLVEP
                     CQSQLFTPNRPKKREIYNPKSVVLDLCSINKTTKPRYPIFMAPQKYLPPLRIVQAIKA
                     PRYKIRELLA"
     exon            225..362
                     /gene="CNBD2"
                     /gene_synonym="C20orf152; CNMPD1"
                     /inference="alignment:Splign:2.1.0"
     exon            363..416
                     /gene="CNBD2"
                     /gene_synonym="C20orf152; CNMPD1"
                     /inference="alignment:Splign:2.1.0"
     exon            417..580
                     /gene="CNBD2"
                     /gene_synonym="C20orf152; CNMPD1"
                     /inference="alignment:Splign:2.1.0"
     exon            581..737
                     /gene="CNBD2"
                     /gene_synonym="C20orf152; CNMPD1"
                     /inference="alignment:Splign:2.1.0"
     exon            738..889
                     /gene="CNBD2"
                     /gene_synonym="C20orf152; CNMPD1"
                     /inference="alignment:Splign:2.1.0"
     exon            890..1028
                     /gene="CNBD2"
                     /gene_synonym="C20orf152; CNMPD1"
                     /inference="alignment:Splign:2.1.0"
     exon            1029..1143
                     /gene="CNBD2"
                     /gene_synonym="C20orf152; CNMPD1"
                     /inference="alignment:Splign:2.1.0"
     exon            1144..1321
                     /gene="CNBD2"
                     /gene_synonym="C20orf152; CNMPD1"
                     /inference="alignment:Splign:2.1.0"
     exon            1322..1442
                     /gene="CNBD2"
                     /gene_synonym="C20orf152; CNMPD1"
                     /inference="alignment:Splign:2.1.0"
     exon            1443..1612
                     /gene="CNBD2"
                     /gene_synonym="C20orf152; CNMPD1"
                     /inference="alignment:Splign:2.1.0"
     exon            1613..1956
                     /gene="CNBD2"
                     /gene_synonym="C20orf152; CNMPD1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1936..1941
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CNBD2"
                     /gene_synonym="C20orf152; CNMPD1"
                     /note="hexamer: AATAAA"
     polyA_site      1956
                     /gene="CNBD2"
                     /gene_synonym="C20orf152; CNMPD1"
                     /note="major polyA site"
ORIGIN      
        1 agagcagggc ttccagtagc tgatggtatg gtaggaggag tggagtggag ctcttgcctt
       61 gttactgagg aaatctattt gtttctagta ttactggatt tttggggaaa aatttgtagt
      121 cctccccttg aaaggcaaag gggctagttg tgccatttgc ctgcacagga accatgagga
      181 gacatatggt aacttatgcc tggcagctcc tgaagaagga actgggactg taccagctcg
      241 ccatggatat catcataatg atccgagtgt gtaaaatgtt ccgccaaggc ctcaggggat
      301 tccgggaata tcaaatcatt gagactgctc actggaagca ccctatcttc tccttctggg
      361 ataaaaagat gcaaagccga gtcacatttg ataccatgga cttcattgca gaggagggtc
      421 actttcctcc aaaggccatt cagatcatgc agaagaagcc ttcctggaga acagaggatg
      481 agatccaggc cgtctgtaac atcttgcagg ttctggatag ctatcggaac tacgcagagc
      541 ccctgcagct gctcctggcc aaagtcatgc gctttgaacg gtttggtcgc aggcgtgtga
      601 tcatcaagaa ggggcagaag ggcaacagct tttatttcat ctacctgggc acagttgcaa
      661 taaccaagga cgaggatggc agcagtgcct tcctagatcc ccacccgaaa ttgctgcaca
      721 agggtagctg ttttggggaa atggacgttc tgcatgcttc agtgaggagg tccaccatcg
      781 tctgtatgga agaaacggag ttcctggttg ttgaccggga ggacttcttt gctaataagc
      841 tggaccagga agttcagaag gatgctcagt atcggtttga attttttagg aagatggagc
      901 tgtttgcatc atggtctgat gagaagctct ggcagctggt agccatggcg aagatagaga
      961 ggttctcgta tgggcagctg atctcaaaag attttggaga gtcacccttc atcatgttta
     1021 tcagcaaggg cagctgtgaa gtcctgcggc tgttggacct tggggcctcc ccttcctacc
     1081 gtagatggat ctggcagcac ctggagctga tagatggcag acctctgaag acccacctga
     1141 gtgaatactc tcctatggaa agatttaagg aattccagat caaatcatat cctctgcaag
     1201 actttagctc cttgaaactt ccacatctca aaaaagcctg ggggctacag gggacaagct
     1261 tcagcaggaa gatcagaacc tcaggagaca ctctccccaa gatgctgggc ccgaagatcc
     1321 aatccaggcc tgctcagtcg atcaaatgtg ccatgatcaa tatcaagcct ggtgagctcc
     1381 ccaaggaggc tgcagtgggg gcctacgtga aggtgcacac tgtggagcag ggagaaattt
     1441 tgggtcttca ccaggccttc cttccagagg gtgaatgcga cacacgaccc ttgatcctga
     1501 tgagcctggg aaatgagttg atacggataa ggaaggaaat attttatgaa ctgattgaca
     1561 atgatgacga gatgataaaa aagttgttaa agctcaatat tgcattcccc agtgatgaag
     1621 atatgtgcca gaagttcctc cagcagaaca gctggaatat ctttcggaag gacctgttgc
     1681 agctgctcgt ggagccttgc caaagtcaac tgttcactcc aaaccggccc aagaagagag
     1741 agatctacaa ccctaagtct gtggtcctgg atttgtgcag catcaacaag acgactaaac
     1801 ctcgttatcc tatttttatg gcaccccaga aatacctccc cccattgagg attgtccaag
     1861 ccatcaaagc acctcggtac aaaatccgag aactcttggc ttagtgtaag agcacagggg
     1921 tccttattta ggacaaataa aggatggtgg attggg
//
