LOCUS       NM_001010852           11219 bp    mRNA    linear   PRI 02-APR-2024
DEFINITION  Homo sapiens clavesin 2 (CLVS2), mRNA.
ACCESSION   NM_001010852 XM_069035
VERSION     NM_001010852.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 11219)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 11219)
  AUTHORS   Tao,S., Wang,Z., Feng,J., Hsu,F.C., Jin,G., Kim,S.T., Zhang,Z.,
            Gronberg,H., Zheng,L.S., Isaacs,W.B., Xu,J. and Sun,J.
  TITLE     A genome-wide search for loci interacting with known prostate
            cancer risk-associated genetic variants
  JOURNAL   Carcinogenesis 33 (3), 598-603 (2012)
   PUBMED   22219177
REFERENCE   3  (bases 1 to 11219)
  AUTHORS   Katoh,Y., Ritter,B., Gaffry,T., Blondeau,F., Honing,S. and
            McPherson,P.S.
  TITLE     The clavesin family, neuron-specific lipid- and clathrin-binding
            Sec14 proteins regulating lysosomal morphology
  JOURNAL   J Biol Chem 284 (40), 27646-27654 (2009)
   PUBMED   19651769
  REMARK    GeneRIF: Clavesin protein family appears to provide a unique
            neuron-specific regulation of late endosome/lysosome morphology.
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AK095527.1, AL591428.2,
            AK295158.1 and BM684470.1.
            
            On Nov 23, 2018 this sequence version replaced NM_001010852.3.
            
            Summary: This gene encodes a protein that belongs to the
            SEC14/CRAL-TRIO family of proteins. A similar protein in rat is
            thought to function in the endosomal pathway between early
            endosomes and mature lysosomes. [provided by RefSeq, Aug 2013].
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660809.11381.1,
                                           SRR1660803.190165.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2145743, SAMEA2154665
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000275162.10/ ENSP00000275162.4
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-51                AK095527.1         269-319
            52-52               AL591428.2         17456-17456
            53-2271             AK095527.1         321-2539
            2272-2272           AL591428.2         85148-85148
            2273-2728           AK295158.1         999-1454
            2729-10491          AL591428.2         85605-93367
            10492-11214         BM684470.1         16-738              c
            11215-11219         AL591428.2         94091-94095
FEATURES             Location/Qualifiers
     source          1..11219
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6q22.31"
     gene            1..11219
                     /gene="CLVS2"
                     /gene_synonym="bA160A10.4; C6orf212; C6orf213; RLBP1L2"
                     /note="clavesin 2"
                     /db_xref="GeneID:134829"
                     /db_xref="HGNC:HGNC:23046"
                     /db_xref="MIM:616945"
     exon            1..512
                     /gene="CLVS2"
                     /gene_synonym="bA160A10.4; C6orf212; C6orf213; RLBP1L2"
                     /inference="alignment:Splign:2.1.0"
     exon            513..1460
                     /gene="CLVS2"
                     /gene_synonym="bA160A10.4; C6orf212; C6orf213; RLBP1L2"
                     /inference="alignment:Splign:2.1.0"
     CDS             1072..2055
                     /gene="CLVS2"
                     /gene_synonym="bA160A10.4; C6orf212; C6orf213; RLBP1L2"
                     /note="retinaldehyde binding protein 1-like 2; clathrin
                     vesicle-associated Sec14 protein 2"
                     /codon_start=1
                     /product="clavesin-2"
                     /protein_id="NP_001010852.2"
                     /db_xref="CCDS:CCDS34525.1"
                     /db_xref="GeneID:134829"
                     /db_xref="HGNC:HGNC:23046"
                     /db_xref="MIM:616945"
                     /translation="MTHLQAGLSPETLEKARLELNENPDTLHQDIQEVRDMVITRPDI
                     GFLRTDDAFILRFLRARKFHHFEAFRLLAQYFEYRQQNLDMFKSFKATDPGIKQALKD
                     GFPGGLANLDHYGRKILVLFAANWDQSRYTLVDILRAILLSLEAMIEDPELQVNGFVL
                     IIDWSNFTFKQASKLTPSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFL
                     KEKTRKRIFLHGNNLNSLHQLIHPEILPSEFGGMLPPYDMGTWARTLLDHEYDDDSEY
                     NVDSYSMPVKEVEKELSPKSMKRSQSVVDPTVLKRMDKNEEENMQPLLSLD"
     exon            1461..1635
                     /gene="CLVS2"
                     /gene_synonym="bA160A10.4; C6orf212; C6orf213; RLBP1L2"
                     /inference="alignment:Splign:2.1.0"
     exon            1636..1746
                     /gene="CLVS2"
                     /gene_synonym="bA160A10.4; C6orf212; C6orf213; RLBP1L2"
                     /inference="alignment:Splign:2.1.0"
     exon            1747..1967
                     /gene="CLVS2"
                     /gene_synonym="bA160A10.4; C6orf212; C6orf213; RLBP1L2"
                     /inference="alignment:Splign:2.1.0"
     exon            1968..11219
                     /gene="CLVS2"
                     /gene_synonym="bA160A10.4; C6orf212; C6orf213; RLBP1L2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5267..5272
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CLVS2"
                     /gene_synonym="bA160A10.4; C6orf212; C6orf213; RLBP1L2"
                     /note="hexamer: ATTAAA"
     polyA_site      5289
                     /gene="CLVS2"
                     /gene_synonym="bA160A10.4; C6orf212; C6orf213; RLBP1L2"
                     /note="major polyA site"
     regulatory      7692..7697
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CLVS2"
                     /gene_synonym="bA160A10.4; C6orf212; C6orf213; RLBP1L2"
                     /note="hexamer: AATAAA"
     polyA_site      7714
                     /gene="CLVS2"
                     /gene_synonym="bA160A10.4; C6orf212; C6orf213; RLBP1L2"
                     /note="major polyA site"
     regulatory      11193..11198
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CLVS2"
                     /gene_synonym="bA160A10.4; C6orf212; C6orf213; RLBP1L2"
                     /note="hexamer: AATAAA"
     polyA_site      11219
                     /gene="CLVS2"
                     /gene_synonym="bA160A10.4; C6orf212; C6orf213; RLBP1L2"
                     /note="major polyA site"
ORIGIN      
        1 gtcctctttc agcagcagca gccggagccg ccgccgcagc ccggtggggc aaccctgact
       61 cggaccgctc gggagagccc caggagaggc cagcgccgcg cagcagccgc cccgctgcgc
      121 ccacctcccc ggctgctccc ggagggctca caaaggcggt ggccgcccga gtggccttct
      181 ccatccaggc gttcgcgtcc tcctccccac cttctctccc gaaggcgaaa atggcagggc
      241 caggcgagaa cctgggacag cggtggccct agccctgcga tcctcacccc tcctgctagg
      301 agaggctgcg ggctgcccgc ggacgatgtg gccgcggctg ctcccgagcg catcttcggc
      361 ccgggtcccc gccgccaccc ctcttctctg ctccttccat cccgcccaga ggagttgatg
      421 ccgctgtcgc cgccgccgcc gctgctgaag ccgcggctga tggatgccag ggagtgccgc
      481 attgcttagc gaccccgcct ctgggtttgc tgatgatctc tctccgccct ggagctcagc
      541 gctgaagagc taccttatta ttaatcagaa tttccatcgc cacccctggc aggcgtatcc
      601 ttcagcaggg accgcaggaa cattcacagt gcaggggctg agatgtgcgt gggggttgtt
      661 tttgttacat cttggaagag aagagaagag gacagtacca agatcagaaa cacccgtgct
      721 aggtggaatt aggggtgatt tgttaggaaa gagaaaggac aagaagagga gtgcggagcc
      781 cttcaggggt tcacatctct ttaaaggaaa ggaaagaggg agccaaagta gggtgttgta
      841 ttttaggggg cagaggaaga agtttacacc ccccggcccc cccagctttg ctgggggaaa
      901 gcaggagcaa cagggcactt gattggacac caagattatt aatttcctgt aggggagagg
      961 aagcaggcag caggaggtct gggggctgga gtctggtggt ggcaaggacc aggtttgctt
     1021 tgggacagtc aacaaggtct tctgagggaa agctcagaga taggcagaac aatgactcat
     1081 ttgcaagccg gtctctcccc tgagaccctg gagaaagctc gcctggagct caatgaaaac
     1141 ccagacacgc tgcaccagga catccaggag gtgagggata tggtcatcac caggccggac
     1201 attggctttc tgcgcacgga tgatgccttc atcttacgct tcttgcgggc taggaagttt
     1261 catcactttg aggccttccg cctcctggcg cagtactttg agtaccggca gcagaacctg
     1321 gacatgttca aaagctttaa ggccaccgac cctggcatca agcaggcact gaaggatggc
     1381 ttccctgggg gcctggccaa tctggaccac tatggcagga agattctagt cctttttgct
     1441 gccaattggg atcagagcag gtacacactg gtggatattt tgcgtgccat cttactttct
     1501 ttagaagcca tgattgaaga tcctgagctt caagtgaatg ggtttgtttt gatcatagac
     1561 tggagtaact tcactttcaa gcaagcctct aaactcacac caagtatgct gcgattagct
     1621 attgaaggcc tgcaggatag tttcccagcg cgatttggag gaattcattt tgtcaatcaa
     1681 ccatggtata tccatgccct gtacaccgtg atccggcctt tcctgaagga gaaaactcgg
     1741 aaaaggatat ttttgcatgg taacaacctg aacagtctac accaactaat tcatcctgag
     1801 atcctgccct ctgagtttgg aggaatgctg cctccttatg acatggggac atgggcaaga
     1861 acactgctag accatgaata tgacgatgac agcgagtaca atgtagactc ctacagcatg
     1921 cctgtgaagg aagtagagaa ggaactctcc ccaaagtcca tgaagagatc tcaatcagta
     1981 gtggatccta cagtactaaa acgcatggat aaaaatgagg aagaaaacat gcaaccattg
     2041 ctttctctgg actaataact tctctacatc cccttcatgg attagaaatg gaaagtattg
     2101 gttttcagca acagggacaa cactgtagag gaattaccag ctggaaaccg acttattcat
     2161 gttaatgtag cataatatat aacaaggcat caggctttcc ttggcctgaa ccatgggggc
     2221 cctgggctgg atttttaaaa tgtcaataat ttattctgta agtgccaagt tgtttgtaaa
     2281 tataatgtaa tcttcatgtc aagtttgtaa atttcagtag taactcagtt tggaaaaagg
     2341 ttggctcaaa agtccatgcc agtgttatga actataacaa aaagcagaaa agacacagtc
     2401 aaagctaatt aaatgtagcc ctctttccta tgaagccata tttcagctct catagtgatt
     2461 gtttcattgt ttttctctga aactctgtca gtattcaaac atactcttaa cgggcacaca
     2521 caactaagtg attccaggaa attttatgat taatgtattt cctgtctagt gattttcatt
     2581 tcagagaaat gtgtcttagt aactatcatt ggccttgcat tttggaggca aggaatggca
     2641 gatgagctgg taaactgaac acttgaactc ttctatgttg tttaattctt ggaatcttgt
     2701 gaaaagatgt gtttcctcaa ttaagacgta gaaatgtaaa aaagagtgga ttctttttaa
     2761 attgctgtct tcacaatgtg ccctttattc aagaccctat tatatttctt cctaatgtac
     2821 tctaagtaca tttcccctcc aaaactcttt gactaagaga atgagaactc atgtgaacag
     2881 tgttctgaca gctaattttg aacataaaat tttccactta cagatgaggg gctaatttct
     2941 aattgttgtg cactggttaa aaagtatata tatatatata ttcacacata tatattttta
     3001 ctgagctcta ataaatcctt aatgtgacag gcttataaaa taaatcatag atattcaatg
     3061 atcttatgga taattacatg agataactct ggaaaactac ttccactgaa gttaatgaaa
     3121 aggagaaata gtgaaactga ctttcagtgt acctatttaa aggaattcca agttaattta
     3181 taatgcaatc ttacatatgt gccatcttat ttgaactata tttttccttc aaagaagcaa
     3241 taggtctcaa catagtgtag gtagcatcag gtgacagaaa gccaatttta ttttcaaatt
     3301 taagttaatt atcttcgtga tcctatttat ccacaatttc tttcagaaaa gactgaaaaa
     3361 acacattata ttcaggagat ataatgaaat tattggaagg catctatgac aacatgtaat
     3421 catttatacg tggatttaga aatttgcata tttaacattt tatttcataa aatttataca
     3481 attacagcaa atcttaattt tttaatttta aatttcaatg tgaaaaaatg atttttatca
     3541 cccataataa attttgagat tgagagttta ccattaaagt attcttttgg aagaaaaata
     3601 tctcagaaac tcttggaaac caacaaaaat aaaggcatgt gtcagccttc atattttttg
     3661 gccaaaagct cccaaaattt gttataattc tgcagccaaa aattgtaaaa gcaagctgaa
     3721 tacaccaatg tacagtgtat caatggactg cctcatgtgt gtaaaaatac attaattaac
     3781 acaaatgaaa gataccttaa taatgccaac ctccagtcaa gtgcagaaga ataatgactg
     3841 tcaggcactc tgctctcctt gtgactttta cagagattgg aatgcactgg ggacaacatg
     3901 tctcagcagt tcttaccttt ataagaattc taaccattga tattcttaca ttcttgccta
     3961 cctgacatac attttgtagc catgggcttt ttagactata taaatcttag gcagtataat
     4021 ccattggaat aaaatagaaa cattgtaagt gcagagggca gtcaactttt cattctcatg
     4081 agtttctctt gatgtgtacc atttattgcc agttttcaga attctgccag tttcagatgt
     4141 caaccagcat tggcagcttc tttcccctat cgtaaagtta gtgtcatata taaaaataac
     4201 tagaaaggca tattttatat gtatgcctat ctaattataa gtatcattca cactgtctcc
     4261 cagacccaca tttggaaagt ttgcattgca ttactgctca tctttagatg agcaattgag
     4321 agttggctag attgtgtaaa atattttaaa atgaatgaac aaattacaat gatgatgcct
     4381 tttgaaatta ccatatctag ttcattctgt gaataaactc attttctagt aatgtttgtg
     4441 aaccttagtc aagggatatt cattcaactt tataaattta cccctcagca ccagctatct
     4501 agcactgttt aggaattttt cccttcatga tattctgtgt cacatcctat gtctatgaat
     4561 aacctataca ctatagttgt atgcctataa gcactcctat actcttgtat tttaattgca
     4621 atagtatacc tccactctct ctctctctct catacacaca cacacacaca ctcttacaca
     4681 cacactaaca cactagactg tttgccctaa tgaattttcc tctgtacttc gagagctatt
     4741 ttagttgtct tgtcacttga aatttgcggg cttcaaagaa ttatcgcatt tgacttggaa
     4801 tggtccagta gtccatttac ttctttcacc ctgcctgttc catcttctat ttctgatatt
     4861 ttttctttct tccagttatt tcaggggcag gtgattccaa agctggttta aaaataaata
     4921 acttctctta tgttgtcagt gatgtttgcc tgcatttttg actactattt aagagggaag
     4981 agattatcat gaaaatatac tctaagaaat atgaagaagt gcctctttga aaatggaata
     5041 aagcaacgtt actggcatat ggattttatt tgtactctct tccaaaaagt aaatacgtaa
     5101 atctatatta tataggtgaa atatagatat catttgaaga aggatattta aggcctttat
     5161 ttgaacatac tcatacagta ttaagtctct gttgtgtaag ttaaatacag taactttagt
     5221 acatgttaat gataaacgtg gcactaggct aaaacgatat acgagtatta aacagagttt
     5281 tgcaagcaag tttttgaagt gggcatgcat gaattctttc atttcagtaa tggtttgcat
     5341 aagtgtagac agagatattt cctaagtttt ttcatataga atacttattt actttatagt
     5401 accaaaaatt catacattca taagcaggaa agccaaaaat tcatacatta atacttagct
     5461 tttttaatac tgttaactag gtcatattgt taaacatgtg aagcgtctgt aatattcctg
     5521 agggaaaaga ggtccctcta ttgcatcaag aaattggaga gttgttttag acattgggga
     5581 atatgtttat gactcttcac ataaagaaac cttcagagcc atggagtatg tcttcaggga
     5641 cagggatcat ttgcttctac aatgtaaagg tttatggaca tatctctggt cctttaaaga
     5701 agttacatta agaaagcttg ctgagaggct gtacactctt ctgttgtttt atttaaaggt
     5761 ctgccttgtg tggttggtga ataatatctc agcttctttt tttgtgtata tttattaatg
     5821 attacatgaa aagttgccat cagccatgag gacacttcaa aaattttcaa cacactaaat
     5881 aaaatgagca gagctctagc atgatatttg aactttcaga tatggtatat gtacattttt
     5941 tacaacaata agctcatagg catatattcc attgtagatc tgctatataa atacatagcc
     6001 tgaaacatag taatgcattt gaaatttgtg aggtcactga tcatacaaga agaggcagat
     6061 tataaaccaa catattggaa caaaagaaga ttggttaaat atgcaaggtg tgtaattatc
     6121 ttcagtaatg aaaaggattt gttttcttgt ttttgtcttt ggttttagtt gaaaaaatag
     6181 cttcccatat gctactggaa ctatttgaca ttatttgcta catgaaaaaa ggcaaataag
     6241 taaacataca aaagaagctt ggctttgtaa cattattata ttatgatctc aatggcttag
     6301 agaatataat cttttttaag aattaaagat tttattttat aaatatttgg aggttaacat
     6361 aggacatgaa aatagtgctg tggattctgt tatgtactaa ctatgggaat gaattctcca
     6421 gtaccatagg aaaatatata agataacaac tttgtggatt gaaacactca aattagcctt
     6481 tttttcaagg aagcaggtgt acaaatgatg ctattgaaat aaaaaaatgt agaaatcact
     6541 taattatagg agttaaatat aatcaatgca ctcatggtaa ataatggaaa ttgttaaaat
     6601 ttagaagagt tttgtcatta tttgacttag atttaagtct cagtgcaaat atgtctgtcc
     6661 ttgatatagt gcatttattc tgtaagactt attttacctg gtgaacgaga tggacttagg
     6721 tgaaaataaa ttttaaccac agttttaagg gtcacccaat cctcaactac tttaaaaaat
     6781 tgcaatgaat tttaattcat ttacttttaa cagagataca aagcactgtc ttgtttctaa
     6841 tccaattttt caatttttca gattttatat ttgcttaaac aataaataaa actcagaaaa
     6901 ccaaatagtt tttgttttca aagctatcca ggaaaaataa aagatgtcta acaggaaatc
     6961 atacaagtcc ttgaagaata ctgagtatat tatttgctat tttactcaaa tgttattaat
     7021 ttttactact acaaactact tatttagtac tacacggcat ttactatttg gccttttgaa
     7081 ggagttataa attccaaaac actataatat aatttttgga caagtataca tttctgttta
     7141 aaagaaatgt atgcttttat tttgtatatt ttatatttta aatgtataca tttattttgc
     7201 acattgttaa tgttaaattt ggtagtcctg gatctgctgc atctataaaa tggagatttc
     7261 tttaaaaaat cgtctaaaaa ttagcaatat ttttattttg agagaaattg tgcttagcta
     7321 tttaagttaa gattcctcaa gtttgtgata tttgtatgtg tggggatcaa agaggaaaat
     7381 atatagtaat ttgtttcatc aaaatgacgt attcaatatt ctataacttc tagtcaaact
     7441 ttcaaatgaa agtttgaaag aagtaaacta atgttttaat tacatatagc aaaggaatga
     7501 tcagtaaata aaataactag ggttttcaca tttgcaatag aatgactgga ttaggcaaga
     7561 gattaaattt agaaatttga attacagaaa agcattggtt taaataaatc ctcaaaaaag
     7621 taatcccagg tcaaaatatg atgtgaaatt aaaaaaaaaa ttcagcctga tttgagaaag
     7681 aatgcttact caataaatat gtatttgtgt cttctgtgag tttccctcat ttatcctatc
     7741 tgtggatgaa aagtcatcta ataaggtata agagactcaa ttacatttac ctagaaccat
     7801 ctacaagtag acttcatgaa tttctttggc tcaaactcag aggattttct ttacacagga
     7861 ttcttgaggt tatcaagaat cgttattgct gctccctcct aaaggcaggc caggagaagc
     7921 cacatttcca gcagtagtat cctcagtggg aatgaaccag aaaacaaaga aaaagccaga
     7981 gatattgtct ccactctcgt tacaaaaaag tgcgttcctt cttcaggagg atcgagtaga
     8041 aaatattttc tactcgaaga ggccatgggg aagtgatggt caaatctctg ttgtgaagca
     8101 agtttccaca cagaaacatc atcaaaaaca cgtacctctg agcatcactt ctttctctaa
     8161 aaataaaaat aaatatgctg ttttcctccc ttttttctaa ttggcatcat aaaagtataa
     8221 gaagccacaa atgcattgtt gccacttaag aaaaaaatcc tatgttatac atatatgaac
     8281 ataattcact tagttgcata tgattgaaat atttgcatgc tggtttataa attattacct
     8341 aaaagtttta tgaaatataa ttattaagtt ttagtgctag aaaaattgtt gttttttgtg
     8401 ttttgtattc atagggaaga ctagtaatat cccttactcc tcattcatat agctaacaat
     8461 tttaattgga tggctaatgg atatggcgga tttaacattt acaaaaccaa actactttca
     8521 ctctgaccct gcttcccctt tagccttctc atctcactat gtgtcgaccc caatcttcca
     8581 gtttctagga ataaaaattt tggagtcatc ctctctttcc ttcctctttt tctttcaaaa
     8641 ctacatcaca tcagctagct catgctgttg ggtcttcaaa atatatccac actctaacca
     8701 cttctccaat cttcttcact gtattggacc aagtcttcaa cattttccat ctggaatatt
     8761 ttaataatct aaaaactagt cttcttgctt ccagagtcaa ttttcaacac attagcaaga
     8821 gtgagtctct taaaatgtaa ctcagaccat tttgttctcc aaaccctctg aaagagtaaa
     8881 agccgatgtc tttatatcag tgtatgagaa gtcttgatat gaaggcagta agcaccagta
     8941 cagcaacata gcatggtttc tgattgggct ggcatttttg ctggtactat gaaaaaatag
     9001 ttgttaaata ctttaatttc ttgcttctga agttctctac cccgttcttg ccttttctta
     9061 gataatctct taagaatctc tcctttattt actgctgcca aactgtcatc tttgctgttc
     9121 caggaacttg ctaagcatgc ctctacctca ggactttcgc atttctgttc cctttgcctc
     9181 taatttcaga tatccacgtg gtttattccc tcatcttctt caggtatttg cttaaatgtc
     9241 atcttctttg tgaggactct ctttcctaat tttagatgaa acagccctgt ggttcttcat
     9301 attctccttt cctgctgtat ttcctctcca tagcatttat cacctgatac accatacaga
     9361 ttatttattt actttgcatt tccccccaat agcaatgtga actccacaag ggcaggaatt
     9421 tttgtctgtt tactactgca ttactggtgc cttgtacagt ccctggaact taacaaatcc
     9481 aaaatgattt catgaggatc ctaatttgtt tcagcaagtt atgtaacggc caatagtatg
     9541 aattgaaaga gtttcttgtt gtcttaattt aaaaaatttt gttatttatc ttcaaagggg
     9601 aaattttacc ctctcatgat aatagaatca tgaatcaaaa atgatatcct cttctcccca
     9661 attgtgatct ctatccctga gcctaagttt tacatcagta tttcagtttt gtctttagaa
     9721 gttactcaac gatcactgga ccctatatct atccacatgg cttactcttg gagagactac
     9781 aagatagctc aggggaaaag tcattttgag attaaaacta catggaattg ttctttatgg
     9841 attatcatgg ttaatttcaa tttttaaaaa tatgcaggaa gttaaaagac tataattcca
     9901 gtattggaag ccagtttaag agaatatgac tatgtagtta cttttaatgg aaaggggaag
     9961 aagaggaaga aaaaggaaag acattgtgtt cgtatcttct ctgcaacaat tataaaatga
    10021 atgaggaagt attttggtgt ttctaaggtc tttccatgat cttgaaatct atatattata
    10081 gtcatttagt ctgtgaacca ttttaacaat tgggtttcat gttacatatc tttaaatttt
    10141 tatgttgaaa atttatagct gtgacacaag atgatagaaa ttgctcatgc tcacatatat
    10201 tccaactggc ttttcagctt gctcccttct cttttaattt cagctatcat ttttagagcc
    10261 ttacagtcac aattgttctt aactatccca aatttttatt tcctatttgg actgacttct
    10321 ccataatttt agtaactaaa tgacctagat attggttctt gttgtgatag gtttctgatt
    10381 tgtatccttt gcagtttaac ttttaatcct taccaaacat atgttattcc ttttcttcag
    10441 ctacattgtt gtgcctttcc caacactgta ataatttaag cctcctgttt tataatcttc
    10501 tatcagaaca tatattaaga agacactgaa tttaaagaat cagcaggtga tgttgaagaa
    10561 gaaatataac ctgaaatata agaatagatg tttgaaactg tttcagaagt taaccagtct
    10621 tttagtggct ttgtaatggg taggggtttt attcctcttt gtgtgctatg taggacattg
    10681 ttaaccaata tagattatgt ttcttgtcag ttacacaagg ataggtaatc agggttaaca
    10741 gttcggaaaa cattctctag agaagagact aatgattctt gctcacaaac aaggcagaat
    10801 ttccttatgt ttcttaatat ttgatccttg atagtctgta cagtggaaac catttccctc
    10861 tgtgatatcc ttttttgcca acctatatga atgtgtttag cgtcacttca gatatagagt
    10921 tcaagctcaa gtatacacag cacatgaaag atcctatagt tcatgttctc ttaggttgaa
    10981 ttttcttttc ataatttttt atgattgaat tctaagggta tgttccttgg taaattgtgt
    11041 taattatgtc cactttataa tggatttaac aattttacaa agcagatcat tgtttattat
    11101 attctgaaaa ccattatatt aatattttat ttcttttttt gcagagaaac tattgtcttt
    11161 tttgatttct gaggatgaat gaagtactgt taaataaaat gtcactaaat gaaacttca
//
