LOCUS       NM_001080511            1531 bp    mRNA    linear   PRI 09-FEB-2024
DEFINITION  Homo sapiens C-type lectin domain family 2 member L (CLEC2L),
            transcript variant 1, mRNA.
ACCESSION   NM_001080511 XM_498242
VERSION     NM_001080511.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1531)
  AUTHORS   Venter,J.C., Adams,M.D., Myers,E.W., Li,P.W., Mural,R.J.,
            Sutton,G.G., Smith,H.O., Yandell,M., Evans,C.A., Holt,R.A.,
            Gocayne,J.D., Amanatides,P., Ballew,R.M., Huson,D.H., Wortman,J.R.,
            Zhang,Q., Kodira,C.D., Zheng,X.H., Chen,L., Skupski,M.,
            Subramanian,G., Thomas,P.D., Zhang,J., Gabor Miklos,G.L.,
            Nelson,C., Broder,S., Clark,A.G., Nadeau,J., McKusick,V.A.,
            Zinder,N., Levine,A.J., Roberts,R.J., Simon,M., Slayman,C.,
            Hunkapiller,M., Bolanos,R., Delcher,A., Dew,I., Fasulo,D.,
            Flanigan,M., Florea,L., Halpern,A., Hannenhalli,S., Kravitz,S.,
            Levy,S., Mobarry,C., Reinert,K., Remington,K., Abu-Threideh,J.,
            Beasley,E., Biddick,K., Bonazzi,V., Brandon,R., Cargill,M.,
            Chandramouliswaran,I., Charlab,R., Chaturvedi,K., Deng,Z., Di
            Francesco,V., Dunn,P., Eilbeck,K., Evangelista,C., Gabrielian,A.E.,
            Gan,W., Ge,W., Gong,F., Gu,Z., Guan,P., Heiman,T.J., Higgins,M.E.,
            Ji,R.R., Ke,Z., Ketchum,K.A., Lai,Z., Lei,Y., Li,Z., Li,J.,
            Liang,Y., Lin,X., Lu,F., Merkulov,G.V., Milshina,N., Moore,H.M.,
            Naik,A.K., Narayan,V.A., Neelam,B., Nusskern,D., Rusch,D.B.,
            Salzberg,S., Shao,W., Shue,B., Sun,J., Wang,Z., Wang,A., Wang,X.,
            Wang,J., Wei,M., Wides,R., Xiao,C., Yan,C., Yao,A., Ye,J., Zhan,M.,
            Zhang,W., Zhang,H., Zhao,Q., Zheng,L., Zhong,F., Zhong,W., Zhu,S.,
            Zhao,S., Gilbert,D., Baumhueter,S., Spier,G., Carter,C.,
            Cravchik,A., Woodage,T., Ali,F., An,H., Awe,A., Baldwin,D.,
            Baden,H., Barnstead,M., Barrow,I., Beeson,K., Busam,D., Carver,A.,
            Center,A., Cheng,M.L., Curry,L., Danaher,S., Davenport,L.,
            Desilets,R., Dietz,S., Dodson,K., Doup,L., Ferriera,S., Garg,N.,
            Gluecksmann,A., Hart,B., Haynes,J., Haynes,C., Heiner,C.,
            Hladun,S., Hostin,D., Houck,J., Howland,T., Ibegwam,C., Johnson,J.,
            Kalush,F., Kline,L., Koduru,S., Love,A., Mann,F., May,D.,
            McCawley,S., McIntosh,T., McMullen,I., Moy,M., Moy,L., Murphy,B.,
            Nelson,K., Pfannkoch,C., Pratts,E., Puri,V., Qureshi,H.,
            Reardon,M., Rodriguez,R., Rogers,Y.H., Romblad,D., Ruhfel,B.,
            Scott,R., Sitter,C., Smallwood,M., Stewart,E., Strong,R., Suh,E.,
            Thomas,R., Tint,N.N., Tse,S., Vech,C., Wang,G., Wetter,J.,
            Williams,S., Williams,M., Windsor,S., Winn-Deen,E., Wolfe,K.,
            Zaveri,J., Zaveri,K., Abril,J.F., Guigo,R., Campbell,M.J.,
            Sjolander,K.V., Karlak,B., Kejariwal,A., Mi,H., Lazareva,B.,
            Hatton,T., Narechania,A., Diemer,K., Muruganujan,A., Guo,N.,
            Sato,S., Bafna,V., Istrail,S., Lippert,R., Schwartz,R., Walenz,B.,
            Yooseph,S., Allen,D., Basu,A., Baxendale,J., Blick,L., Caminha,M.,
            Carnes-Stine,J., Caulk,P., Chiang,Y.H., Coyne,M., Dahlke,C.,
            Deslattes Mays,A., Dombroski,M., Donnelly,M., Ely,D., Esparham,S.,
            Fosler,C., Gire,H., Glanowski,S., Glasser,K., Glodek,A.,
            Gorokhov,M., Graham,K., Gropman,B., Harris,M., Heil,J.,
            Henderson,S., Hoover,J., Jennings,D., Jordan,C., Jordan,J.,
            Kasha,J., Kagan,L., Kraft,C., Levitsky,A., Lewis,M., Liu,X.,
            Lopez,J., Ma,D., Majoros,W., McDaniel,J., Murphy,S., Newman,M.,
            Nguyen,T., Nguyen,N., Nodell,M., Pan,S., Peck,J., Peterson,M.,
            Rowe,W., Sanders,R., Scott,J., Simpson,M., Smith,T., Sprague,A.,
            Stockwell,T., Turner,R., Venter,E., Wang,M., Wen,M., Wu,D., Wu,M.,
            Xia,A., Zandieh,A. and Zhu,X.
  TITLE     The sequence of the human genome
  JOURNAL   Science 291 (5507), 1304-1351 (2001)
   PUBMED   11181995
  REMARK    Erratum:[Science 2001 Jun 5;292(5523):1838]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC005531.2 and HY072821.1.
            
            On Nov 22, 2018 this sequence version replaced NM_001080511.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: ERR279831.9437.1, SRR3476690.63542.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2142680, SAMEA2145743
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000422142.7/ ENSP00000390661.2
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-334               AC005531.2         95189-95522
            335-618             HY072821.1         1-284
            619-619             AC005531.2         111935-111935
            620-818             HY072821.1         286-484
            819-1531            AC005531.2         115777-116489
FEATURES             Location/Qualifiers
     source          1..1531
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
                     /map="7q34"
     gene            1..1531
                     /gene="CLEC2L"
                     /note="C-type lectin domain family 2 member L"
                     /db_xref="GeneID:154790"
                     /db_xref="HGNC:HGNC:21969"
     exon            1..433
                     /gene="CLEC2L"
                     /inference="alignment:Splign:2.1.0"
     CDS             244..888
                     /gene="CLEC2L"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="C-type lectin domain family 2 member L isoform
                     1"
                     /protein_id="NP_001073980.2"
                     /db_xref="CCDS:CCDS47724.1"
                     /db_xref="GeneID:154790"
                     /db_xref="HGNC:HGNC:21969"
                     /translation="MEPAREPPSRARPPPPLAARPAPAPAAPRPRSPAEAEARGPEGL
                     LRRSGSGYEGSTSWKAALEDTTTRLLLGAIAVLLFAILVVMSILASKGCIKCEAPCPE
                     DWLLYGRKCYFFSEEPRDWNTGRQYCHTHEAVLAVIQSQKELEFMFKFTRREPWIGLR
                     RVGDEFHWVNGDPFDPDTFTIAGPGECVFVEPTRLVSTECLMTRPWVCSKMAYT"
     exon            434..508
                     /gene="CLEC2L"
                     /inference="alignment:Splign:2.1.0"
     exon            509..675
                     /gene="CLEC2L"
                     /inference="alignment:Splign:2.1.0"
     exon            676..776
                     /gene="CLEC2L"
                     /inference="alignment:Splign:2.1.0"
     exon            777..1531
                     /gene="CLEC2L"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1512..1517
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CLEC2L"
                     /note="hexamer: AATAAA"
     polyA_site      1531
                     /gene="CLEC2L"
                     /note="major polyA site"
ORIGIN      
        1 agcccggctg tgcgtggagg ctgcggctcg gcggggcagg cgctgagcgc accgcggcgg
       61 cacccggcgc agaggctcca gcgcggggag ccgggctcag ccccggcctg ccagcgccgc
      121 ggtcctagcc cacccgaggc cggcctgggg ggcccgcagg gcgcgcggag cgccgagtgc
      181 gcgtcgggct gggccccgca ccccggtgca ggagcgcggg cgcggcgcgg cggagcgccc
      241 cgcatggagc cggcccggga gcccccctcg cgggcccggc cgccgccgcc cctcgccgcg
      301 cgccccgcgc ccgcccccgc cgcccccagg ccgcgttcgc ccgcagaggc tgaggcccgc
      361 ggccccgagg ggctgctgcg gcgatccggg tcgggctacg agggcagcac cagctggaag
      421 gcggccttgg aggacaccac cacacgcctc ctgctgggtg ccatcgcggt ccttctgttc
      481 gccatcttgg tggtgatgag catcttggct tccaagggct gcatcaagtg cgaagcgccc
      541 tgcccggagg actggctgct ctacggaagg aagtgctact tcttttccga ggaacccaga
      601 gactggaaca caggcaggca gtactgccac acccacgagg cggtgctggc tgtgattcag
      661 agccagaagg agctggaatt tatgttcaag ttcacgcgga gggagccctg gattggacta
      721 cgcagagttg gggacgaatt ccactgggtc aacggggacc cgtttgatcc ggacacgttc
      781 accatcgcag gtccagggga gtgtgtcttc gtggagccca ccaggctggt gtcgacggag
      841 tgtctgatga cccggccctg ggtgtgcagc aagatggcct atacttgagg tgggtggggc
      901 cagaggtggc cccgccccta ggcctgtggg aggtgtctgg tgtctgctca agacctgctt
      961 ccagcggagc cgcctgccct ctgcaaggcg aagcggtggg tgcgtggcct ccgccccagg
     1021 cccctctccc aggccctggc gctctgagtc cctggttcct ggcctccttt gtctgcaggc
     1081 aggtcgtgtg gctcagcagt taaatcccat atgctaggta gtgtaggcat ctgcccacct
     1141 acacacacac acatgcatag gtacacgcac gcacagacgc tgtcccttct gaagctcagt
     1201 gtccatcctg agccacccca cagatctctc tccggccccc tagaagccct ctcctcactg
     1261 cagccctggt gctctgggga aggaggggca ttgacaggtg gtttgactgt tcacccagca
     1321 gccccgcttc cccactggtt tctctcctgg ctgccggcgg aggtaggctg ggaaagcttc
     1381 cccctcacct aggccgggcc agccccgccc cgggccccag aggtcccctg catccccctt
     1441 ctttgccttg cctgggttct caggcagggc ccctgctgtg tccgtggtgc tgttgtattg
     1501 gtcactaacg gaataaagag ttaatatctc a
//
