LOCUS       NM_173619               1987 bp    mRNA    linear   PRI 02-APR-2024
DEFINITION  Homo sapiens C-type lectin domain family 18 member C (CLEC18C),
            mRNA.
ACCESSION   NM_173619
VERSION     NM_173619.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1987)
  AUTHORS   Huang,Y.L., Pai,F.S., Tsou,Y.T., Mon,H.C., Hsu,T.L., Wu,C.Y.,
            Chou,T.Y., Yang,W.B., Chen,C.H., Wong,C.H. and Hsieh,S.L.
  TITLE     Human CLEC18 Gene Cluster Contains C-type Lectins with Differential
            Glycan-binding Specificity
  JOURNAL   J Biol Chem 290 (35), 21252-21263 (2015)
   PUBMED   26170455
  REMARK    GeneRIF: The human C-type lectin 18 (clec18) gene cluster, which
            contains three clec18a, clec18b, and clec18c loci, is located in
            human chromosome 16q22.
REFERENCE   2  (bases 1 to 1987)
  AUTHORS   Zelensky,A.N. and Gready,J.E.
  TITLE     The C-type lectin-like domain superfamily
  JOURNAL   FEBS J 272 (24), 6179-6217 (2005)
   PUBMED   16336259
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC009060.7.
            
            On May 10, 2019 this sequence version replaced NM_173619.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            CDS exon combination :: BC062573.1 [ECO:0000331]
            RNAseq introns       :: single sample supports all introns
                                    SAMEA1968968, SAMEA1970526 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000541793.7/ ENSP00000444875.2
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-165               AC009060.7         75064-75228
            166-395             AC009060.7         75450-75679
            396-487             AC009060.7         76224-76315
            488-727             AC009060.7         78518-78757
            728-825             AC009060.7         83127-83224
            826-947             AC009060.7         83645-83766
            948-1055            AC009060.7         83924-84031
            1056-1148           AC009060.7         84558-84650
            1149-1255           AC009060.7         85030-85136
            1256-1385           AC009060.7         85771-85900
            1386-1482           AC009060.7         86173-86269
            1483-1574           AC009060.7         87162-87253
            1575-1987           AC009060.7         87760-88172
FEATURES             Location/Qualifiers
     source          1..1987
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16q22.1"
     gene            1..1987
                     /gene="CLEC18C"
                     /gene_synonym="MRCL; MRCL3"
                     /note="C-type lectin domain family 18 member C"
                     /db_xref="GeneID:283971"
                     /db_xref="HGNC:HGNC:28538"
                     /db_xref="MIM:616573"
     exon            1..165
                     /gene="CLEC18C"
                     /gene_synonym="MRCL; MRCL3"
                     /inference="alignment:Splign:2.1.0"
     exon            166..395
                     /gene="CLEC18C"
                     /gene_synonym="MRCL; MRCL3"
                     /inference="alignment:Splign:2.1.0"
     CDS             272..1612
                     /gene="CLEC18C"
                     /gene_synonym="MRCL; MRCL3"
                     /note="mannose receptor-like 3; mannose receptor-like
                     protein 3"
                     /codon_start=1
                     /product="C-type lectin domain family 18 member C
                     precursor"
                     /protein_id="NP_775890.2"
                     /db_xref="CCDS:CCDS32473.1"
                     /db_xref="GeneID:283971"
                     /db_xref="HGNC:HGNC:28538"
                     /db_xref="MIM:616573"
                     /translation="MLHPETSPGRGHLLAVLLALLGTAWAEVWPPQLQEQAPMAGALN
                     RKESFLLLSLHNRLRSWVQPPAADMRRLDWSDSLAQLAQARAALCGIPTPSLASGLWR
                     TLQVGWNMQLLPAGLASFVEVVSLWFAEGQRYSHAAGECARNATCTHYTQLVWATSSQ
                     LGCGRHLCSAGQAAIEAFVCAYSPRGNWEVNGKTIVPYKKGAWCSLCTASVSGCFKAW
                     DHAGGLCEVPRNPCRMSCQNHGRLNISTCHCHCPPGYTGRYCQVRCSLQCVHGRFREE
                     ECSCVCDIGYGGAQCATKVHFPFHTCDLRIDGDCFMVSSEADTYYRARMKCQRKGGVL
                     AQIKSQKVQDILAFYLGRLETTNEVIDSDFETRNFWIGLTYKTAKDSFRWATGEHQAF
                     TSFAFGQPDNHGFGNCVELQASAAFNWNNQRCKTRNRYICQFAQEHISRWGPGS"
     exon            396..487
                     /gene="CLEC18C"
                     /gene_synonym="MRCL; MRCL3"
                     /inference="alignment:Splign:2.1.0"
     exon            488..727
                     /gene="CLEC18C"
                     /gene_synonym="MRCL; MRCL3"
                     /inference="alignment:Splign:2.1.0"
     exon            728..825
                     /gene="CLEC18C"
                     /gene_synonym="MRCL; MRCL3"
                     /inference="alignment:Splign:2.1.0"
     exon            826..947
                     /gene="CLEC18C"
                     /gene_synonym="MRCL; MRCL3"
                     /inference="alignment:Splign:2.1.0"
     exon            948..1055
                     /gene="CLEC18C"
                     /gene_synonym="MRCL; MRCL3"
                     /inference="alignment:Splign:2.1.0"
     exon            1056..1148
                     /gene="CLEC18C"
                     /gene_synonym="MRCL; MRCL3"
                     /inference="alignment:Splign:2.1.0"
     exon            1149..1255
                     /gene="CLEC18C"
                     /gene_synonym="MRCL; MRCL3"
                     /inference="alignment:Splign:2.1.0"
     exon            1256..1385
                     /gene="CLEC18C"
                     /gene_synonym="MRCL; MRCL3"
                     /inference="alignment:Splign:2.1.0"
     exon            1386..1482
                     /gene="CLEC18C"
                     /gene_synonym="MRCL; MRCL3"
                     /inference="alignment:Splign:2.1.0"
     exon            1483..1574
                     /gene="CLEC18C"
                     /gene_synonym="MRCL; MRCL3"
                     /inference="alignment:Splign:2.1.0"
     exon            1575..1987
                     /gene="CLEC18C"
                     /gene_synonym="MRCL; MRCL3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcccagtttc tgctcaccag aaggaccata gccgaggtcc tcctcccagg gcccggggct
       61 ggggagcgga agccatcagt gggctcggag gacactgtcc cagccaggac acggccatcg
      121 gtcactaatc tgcagcactg gaatgtccgc aggccaatca gcgggcccag cctgactcct
      181 ggagattgtg aatagctcca tccagcctga gaaacaagcc gggtggctga gccaggctgt
      241 gcacggagtg cctgacgggc ccaacagacc catgctgcat ccagagacct cccctggccg
      301 ggggcatctc ctggctgtgc tcctggccct ccttggcacc gcctgggcag aggtgtggcc
      361 accccagctg caggagcagg ctccgatggc cggagccctg aacaggaagg agagtttctt
      421 gctcctctcc ctgcacaacc gcctgcgcag ctgggtccag ccccctgcgg ctgacatgcg
      481 gaggctggac tggagtgaca gcctggccca actggctcaa gccagggcag ccctctgtgg
      541 aatcccaacc ccgagcctgg cgtccggcct gtggcgcacc ctgcaagtgg gctggaacat
      601 gcagctgctg cccgcgggct tggcgtcctt tgttgaagtg gtcagcctat ggtttgcaga
      661 ggggcagcgg tacagccacg cggcaggaga gtgtgctcgc aacgccacct gcacccacta
      721 cacgcagctc gtgtgggcca cctcaagcca gctgggctgt gggcggcacc tgtgctctgc
      781 aggccaggca gcgatagaag cctttgtctg tgcctactcc cccagaggca actgggaggt
      841 caacgggaag acaatcgtcc cctataagaa gggtgcctgg tgttcgctct gcacagccag
      901 tgtctcaggc tgcttcaaag cctgggacca tgcagggggg ctctgtgagg tccccaggaa
      961 tccttgtcgc atgagctgcc agaaccatgg acgtctcaac atcagcacct gccactgcca
     1021 ctgtccccct ggctacacgg gcagatactg ccaagtgagg tgcagcctgc agtgtgtgca
     1081 cggccggttc cgggaggagg agtgctcgtg cgtctgtgac atcggctacg ggggagccca
     1141 gtgtgccacc aaggtgcatt ttcccttcca cacctgtgac ctgaggatcg acggagactg
     1201 cttcatggtg tcttcagagg cagacaccta ttacagagcc aggatgaaat gtcagaggaa
     1261 aggcggggtg ctggcccaga tcaagagcca gaaagtgcag gacatcctcg ccttctatct
     1321 gggccgcctg gagaccacca acgaggtgat tgacagtgac ttcgagacca ggaacttctg
     1381 gatcgggctc acctacaaga ccgccaagga ctccttccgc tgggccacag gggagcacca
     1441 ggccttcacc agttttgcct ttgggcagcc tgacaaccac gggtttggca actgcgtgga
     1501 gctgcaggct tcagctgcct tcaactggaa caaccagcgc tgcaaaaccc gaaaccgtta
     1561 catctgccag tttgcccagg agcacatctc ccggtggggc ccagggtcct gaggcctgac
     1621 cacatggctc cctcgcctgc cctgggagca ccggctctgc ttacctgtcc gcccacctgt
     1681 ctggaacaag ggccaggtta agaccacatg cctcatgtcc aaagaggtct cagaccttgc
     1741 acaatgccag aagttgggca gagagaggca gggaggccag tgagggccag ggagtgagtg
     1801 ttagaagaag ctggggccct tcgcctgctt ttgattggga agatgggctt caattagatg
     1861 gcaaaggaga ggacaccgcc agtggtccaa aaaggctgct ctcttccacc tggcccagac
     1921 cctgtggggc agcggagctt ccctgtggca tgaaccccac agggtattaa attatgaatc
     1981 agctgaa
//
