LOCUS       NM_174891               2379 bp    mRNA    linear   PRI 09-FEB-2025
DEFINITION  Homo sapiens clathrin binding box of aftiphilin containing 1
            (CLBA1), transcript variant 1, mRNA.
ACCESSION   NM_174891
VERSION     NM_174891.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2379)
  AUTHORS   Guinn,B.A., Bland,E.A., Lodi,U., Liggins,A.P., Tobal,K.,
            Petters,S., Wells,J.W., Banham,A.H. and Mufti,G.J.
  TITLE     Humoral detection of leukaemia-associated antigens in presentation
            acute myeloid leukaemia
  JOURNAL   Biochem Biophys Res Commun 335 (4), 1293-1304 (2005)
   PUBMED   16112646
REFERENCE   2  (bases 1 to 2379)
  AUTHORS   Heilig,R., Eckenberg,R., Petit,J.L., Fonknechten,N., Da Silva,C.,
            Cattolico,L., Levy,M., Barbe,V., de Berardinis,V., Ureta-Vidal,A.,
            Pelletier,E., Vico,V., Anthouard,V., Rowen,L., Madan,A., Qin,S.,
            Sun,H., Du,H., Pepin,K., Artiguenave,F., Robert,C., Cruaud,C.,
            Bruls,T., Jaillon,O., Friedlander,L., Samson,G., Brottier,P.,
            Cure,S., Segurens,B., Aniere,F., Samain,S., Crespeau,H., Abbasi,N.,
            Aiach,N., Boscus,D., Dickhoff,R., Dors,M., Dubois,I., Friedman,C.,
            Gouyvenoux,M., James,R., Madan,A., Mairey-Estrada,B., Mangenot,S.,
            Martins,N., Menard,M., Oztas,S., Ratcliffe,A., Shaffer,T.,
            Trask,B., Vacherie,B., Bellemere,C., Belser,C., Besnard-Gonnet,M.,
            Bartol-Mavel,D., Boutard,M., Briez-Silla,S., Combette,S.,
            Dufosse-Laurent,V., Ferron,C., Lechaplais,C., Louesse,C.,
            Muselet,D., Magdelenat,G., Pateau,E., Petit,E.,
            Sirvain-Trukniewicz,P., Trybou,A., Vega-Czarny,N., Bataille,E.,
            Bluet,E., Bordelais,I., Dubois,M., Dumont,C., Guerin,T.,
            Haffray,S., Hammadi,R., Muanga,J., Pellouin,V., Robert,D.,
            Wunderle,E., Gauguet,G., Roy,A., Sainte-Marthe,L., Verdier,J.,
            Verdier-Discala,C., Hillier,L., Fulton,L., McPherson,J.,
            Matsuda,F., Wilson,R., Scarpelli,C., Gyapay,G., Wincker,P.,
            Saurin,W., Quetier,F., Waterston,R., Hood,L. and Weissenbach,J.
  TITLE     The DNA sequence and analysis of human chromosome 14
  JOURNAL   Nature 421 (6923), 601-607 (2003)
   PUBMED   12508121
  REMARK    Erratum:[Nature. 2023 Aug;620(7973):E17. doi:
            10.1038/s41586-023-06403-y.. PMID: 37491470]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL512802.2, AK057249.1 and AF038188.1.
            
            On Nov 23, 2018 this sequence version replaced NM_174891.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660809.64352.1,
                                           SRR1163655.364791.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000547315.6/ ENSP00000450114.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-491               AL512802.2         67095-67585
            492-927             AK057249.1         1-436
            928-1592            AF038188.1         1-665
            1593-1593           AL512802.2         76037-76037
            1594-2379           AF038188.1         667-1452
FEATURES             Location/Qualifiers
     source          1..2379
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q32.33"
     gene            1..2379
                     /gene="CLBA1"
                     /gene_synonym="C14orf79"
                     /note="clathrin binding box of aftiphilin containing 1"
                     /db_xref="GeneID:122616"
                     /db_xref="HGNC:HGNC:20126"
     exon            1..1067
                     /gene="CLBA1"
                     /gene_synonym="C14orf79"
                     /inference="alignment:Splign:2.1.0"
     CDS             645..1622
                     /gene="CLBA1"
                     /gene_synonym="C14orf79"
                     /note="isoform 1 is encoded by transcript variant 1;
                     uncharacterized protein C14orf79; clathrin-binding box of
                     aftiphilin-containing protein 1"
                     /codon_start=1
                     /product="uncharacterized protein CLBA1 isoform 1"
                     /protein_id="NP_777551.2"
                     /db_xref="CCDS:CCDS42000.1"
                     /db_xref="GeneID:122616"
                     /db_xref="HGNC:HGNC:20126"
                     /translation="MQGRRELGGEPLSDLQEEAASASLRVAPERLSDDSLEWRRTCPD
                     LLLSDGKASISMPREGGSTCTARCPDPGEHSSTWGEFEGFRESSAKSGQFSQSLELLE
                     GPTEPQPPRTTSAPKECSSHQPCQGGPWVTGTSAVPPSEPILSYENILKCAFQEITVQ
                     QAAEDVSTIDHFLEISSEEKPGVERVHKLCNESRKLWRALQSIHTTSTSQRLWSESRC
                     QENFFLVLGIDAAQKNLSGGQGHIMEDCDLKEPEGLLTVSSFCLQHCKALIQTKLSGP
                     PGSKQGRLMTCSRFLKTPSCGGGQHITIPRKRMFTPRKLKLTLFNSDVC"
     exon            1068..1213
                     /gene="CLBA1"
                     /gene_synonym="C14orf79"
                     /inference="alignment:Splign:2.1.0"
     exon            1214..1343
                     /gene="CLBA1"
                     /gene_synonym="C14orf79"
                     /inference="alignment:Splign:2.1.0"
     exon            1344..1460
                     /gene="CLBA1"
                     /gene_synonym="C14orf79"
                     /inference="alignment:Splign:2.1.0"
     exon            1461..2379
                     /gene="CLBA1"
                     /gene_synonym="C14orf79"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2361..2366
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CLBA1"
                     /gene_synonym="C14orf79"
                     /note="hexamer: AATAAA"
     polyA_site      2379
                     /gene="CLBA1"
                     /gene_synonym="C14orf79"
                     /note="major polyA site"
ORIGIN      
        1 aggcaacggg gcggcgcagg caggagggaa cggctggttg caggtttctc tcgccctggt
       61 cccgcgcggc cccgccgagg cggcgaccaa ggtgggtgcg gggactctcg ggagccgtgg
      121 gccaggcgct tagccggcca cctcgggccc tgtccaggcc caggcgttcc agggctgctc
      181 tgcgggccgc gtgcgagagg gactctcggg aggccccggg gcgccgcacc cactccttcc
      241 cacttgggac tcccgcgggc gcccggctct cgctcctctg gccagcgtgg gcctcccagg
      301 ccccctcgcg gctctctcca gagcaggagc cccaccttgg gccgcccctc tcacacctgc
      361 cgtgggtctg gtacgcgcct ctgtgtcgga ctccgcgccc gcctgcgtgg gaggaagcca
      421 ggactcccgg gcgaccgggc cattcctgtg gtttgtgtca gttccacagc agcacgtggg
      481 cactttccac cgtcagccac tgggcagccc ggggcactcc tgcagcgtcc cctggccctc
      541 tccagggcag gggaaggttg ggcagtcctg ggcggccagc accccggcgt gcatgtctcc
      601 tgagcagctg cccatcgggc ctctgctggc ctgggggctc caagatgcaa ggccggcggg
      661 agctgggggg agagcctttg agtgacctcc aggaggaagc agccagcgct tccctccgag
      721 tggcacctga gaggctgagt gatgacagtt tggaatggag acggacctgc cccgaccttc
      781 tcctgtccga tgggaaagcc agcatctcca tgccccgtga gggcggttcc acctgcactg
      841 cccgatgtcc tgaccctggg gaacacagca gcacttgggg ggagtttgaa ggctttcggg
      901 aatcttcagc caagtctgga caattctcac agtcccttga actcctcgag ggacccacag
      961 aaccccagcc accgagaacc acttctgccc caaaagagtg cagttctcac caaccatgcc
     1021 agggtggacc ttgggtgaca ggaacttctg ccgtcccacc ttctgagccc attctcagct
     1081 atgagaacat tttaaagtgt gcttttcaag aaataacagt ccagcaggca gctgaagacg
     1141 tttccaccat agaccatttc ctagaaataa gcagtgaaga aaaacctggc gttgaacgtg
     1201 tacataaatt gtgtaacgaa tccagaaaac tctggagagc ccttcagagc atacacacca
     1261 cgtctacttc tcagcgcctc tggagcgagt cccgttgcca ggagaacttc tttcttgttc
     1321 tcggaataga tgctgcgcag aagaaccttt ctggaggcca gggccacatc atggaagatt
     1381 gtgacctcaa agagcctgaa ggactcctca ctgtcagcag cttctgtctc cagcattgca
     1441 aagccctgat ccagaccaag ctctcggggc cgcctggcag caaacagggg aggctgatga
     1501 catgcagccg cttcctgaag accccctcat gcggaggtgg ccagcacatc actattccaa
     1561 ggaaaaggat gttcactcca cgcaagctca aactgacact ctttaatagc gacgtttgct
     1621 aaaatcagga ggactttgta cctttatgag gaatttttca ttttcttcct ggctgggttg
     1681 atgtggaaac cagagctgtc tgtggagctg ttttccagac cccaggccca ttcctgggat
     1741 ctctccaaca ggacctgtcc tgtgttctgg gcttgtctcg ggtctgacca ggagatggag
     1801 gatgtgtcct tggcagagcc aaggggagac agaggtttct ggatgccatg acaggctgtc
     1861 ggggtccagg tggcactcat gggccccctg ccccatgtga atgctgctgg cacctggtgg
     1921 ggggttgccc agggatggac cctgggcatg gcttctgggc tgcttagtcc agggggagca
     1981 acttgtggcc aaatccatga gttcagagga aaaggggaag gcactgaaac gtcaccagag
     2041 agacagctgt tgagaccgct cagaaaccct ctgtctgtca cactctgccc tggctgctgt
     2101 gtggtcaggg caccatgagg gtgtacagat gtgctgtgtc ctcagagcct cgcaggtgcc
     2161 ctcacttact gcctgggccc ctgcccagca gcctcaagga caggcctttg tccctcacgg
     2221 ttgtggacag gaggtcgcac cactggcctg cgagagcctc tggtgggccc gtggcttccc
     2281 ccagttatct gctaaggaaa actgtgctct tcgaagggca gagccaagaa gtcagccctg
     2341 acttttgtaa aattttacta aataaaacca cctggataa
//
