LOCUS       NM_001204099             781 bp    mRNA    linear   PRI 10-JUL-2022
DEFINITION  Homo sapiens CKLF-CMTM1 readthrough (CKLF-CMTM1), transcript
            variant 1, mRNA.
ACCESSION   NM_001204099
VERSION     NM_001204099.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 781)
  AUTHORS   Prakash T, Sharma VK, Adati N, Ozawa R, Kumar N, Nishida Y,
            Fujikake T, Takeda T and Taylor TD.
  TITLE     Expression of conjoined genes: another mechanism for gene
            regulation in eukaryotes
  JOURNAL   PLoS One 5 (10), e13284 (2010)
   PUBMED   20967262
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC010542.7 and FY212695.1.
            
            On Jun 2, 2019 this sequence version replaced NM_001204099.1.
            
            Summary: This locus represents naturally occurring read-through
            transcription between the neighboring CKLF (chemokine-like factor)
            and CMTM1 (CKLF-like MARVEL transmembrane domain containing 1)
            genes on chromosome 16. The read-through transcript produces a
            fusion protein that shares sequence identity with each individual
            gene product. [provided by RefSeq, Feb 2011].
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FY210992.1, FY212685.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2142670
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            readthrough transcript :: includes exons from GeneID 51192, 113540
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-188               AC010542.7         74560-74747
            189-577             FY212695.1         86-474
            578-781             AC010542.7         100916-101119
FEATURES             Location/Qualifiers
     source          1..781
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16q21"
     gene            1..781
                     /gene="CKLF-CMTM1"
                     /note="CKLF-CMTM1 readthrough"
                     /db_xref="GeneID:100529251"
                     /db_xref="HGNC:HGNC:39977"
     exon            1..218
                     /gene="CKLF-CMTM1"
                     /inference="alignment:Splign:2.1.0"
     CDS             141..647
                     /gene="CKLF-CMTM1"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="CKLF-CMTM1 protein isoform 1"
                     /protein_id="NP_001191028.1"
                     /db_xref="GeneID:100529251"
                     /db_xref="HGNC:HGNC:39977"
                     /translation="MDNVQPKIKHRPFCFSVKGHVKMLRLALTVTSMTFFIIAQAPEP
                     YIVITGFEVTVILFFILLYVLRLDRLMKWLFWPLLDLTNSIITAVFLSVVAILAMQEK
                     KRRHLLYVGGSLCLTAVIVCCIDAFVVTTKMRTNLKRFLGVEVERKLSPAKDAYPETG
                     PDAPQRPA"
     exon            219..377
                     /gene="CKLF-CMTM1"
                     /inference="alignment:Splign:2.1.0"
     exon            378..476
                     /gene="CKLF-CMTM1"
                     /inference="alignment:Splign:2.1.0"
     exon            477..781
                     /gene="CKLF-CMTM1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      750..755
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CKLF-CMTM1"
                     /note="hexamer: CATAAA"
     polyA_site      781
                     /gene="CKLF-CMTM1"
                     /note="major polyA site"
ORIGIN      
        1 agcgggaagc cgagctgggc gagaagtagg ggagggcggt gctccgccgc ggtggcggtt
       61 gctatcgctt cgcagaacct actcaggcag ccagctgaga agagttgagg gaaagtgctg
      121 ctgctgggtc tgcagacgcg atggataacg tgcagccgaa aataaaacat cgccccttct
      181 gcttcagtgt gaaaggccac gtgaagatgc tgcggctggc actaactgtg acatctatga
      241 ccttttttat catcgcacaa gcccctgaac catatattgt tatcactgga tttgaagtca
      301 ccgttatctt atttttcata cttttatatg tactcagact tgatcgatta atgaagtggt
      361 tattttggcc tttgcttgat cttaccaaca gtatcattac agctgtgttc ctttcagtag
      421 ttgccatctt ggccatgcaa gaaaagaaaa gaaggcattt actctatgtc ggggggtccc
      481 tgtgtctcac agcggtaatc gtgtgttgca tcgatgcgtt tgtggtcacc acgaagatga
      541 ggaccaactt gaaaagattc ctgggagtcg aagttgaaag gaagctttcc cccgccaagg
      601 acgcctaccc cgaaaccggc cccgacgccc cgcagaggcc cgcctgaagc cagcccggcg
      661 ccctagcaga tgcacgtgtc tgtcgaatcg ctgcctccga gcccaccccc gagctcgcat
      721 gctgtcaccc attccagcct aaatgtgacc ataaaattag ggctgctgct tttatcgaga
      781 a
//
