LOCUS       NM_001396036             856 bp    mRNA    linear   PRI 18-FEB-2024
DEFINITION  Homo sapiens colon, intestine and stomach enriched 1 (CIST1),
            transcript variant 1, mRNA.
ACCESSION   NM_001396036
VERSION     NM_001396036.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 856)
  AUTHORS   Sun,W., Lan,X., Wang,Z., Dong,W., He,L., Zhang,T. and Zhang,H.
  TITLE     Overexpression of long non-coding RNA NR_036575.1 contributes to
            the proliferation and migration of papillary thyroid cancer
  JOURNAL   Med Oncol 33 (9), 102 (2016)
   PUBMED   27510368
REFERENCE   2  (bases 1 to 856)
  AUTHORS   Lan,X., Zhang,H., Wang,Z., Dong,W., Sun,W., Shao,L., Zhang,T. and
            Zhang,D.
  TITLE     Genome-wide analysis of long noncoding RNA expression profile in
            papillary thyroid carcinoma
  JOURNAL   Gene 569 (1), 109-117 (2015)
   PUBMED   26003293
REFERENCE   3  (bases 1 to 856)
  AUTHORS   Larson,J.H., Kumar,C.G., Everts,R.E., Green,C.A., Everts-van der
            Wind,A., Band,M.R. and Lewin,H.A.
  TITLE     Discovery of eight novel divergent homologs expressed in cattle
            placenta
  JOURNAL   Physiol Genomics 25 (3), 405-413 (2006)
   PUBMED   16554549
REFERENCE   4  (bases 1 to 856)
  AUTHORS   Harrington,J.J., Sherf,B., Rundlett,S., Jackson,P.D., Perry,R.,
            Cain,S., Leventhal,C., Thornton,M., Ramachandran,R.,
            Whittington,J., Lerner,L., Costanzo,D., McElligott,K., Boozer,S.,
            Mays,R., Smith,E., Veloso,N., Klika,A., Hess,J., Cothren,K., Lo,K.,
            Offenbacher,J., Danzig,J. and Ducar,M.
  TITLE     Creation of genome-wide protein expression libraries using random
            activation of gene expression
  JOURNAL   Nat Biotechnol 19 (5), 440-445 (2001)
   PUBMED   11329013
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC008397.7.
            
            On Nov 17, 2022 this sequence version replaced NM_001396036.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA1966682, SAMEA1968540
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000643046.2/ ENSP00000496487.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-143               AC008397.7         24524-24666         c
            144-551             AC008397.7         21368-21775         c
            552-712             AC008397.7         19616-19776         c
            713-856             AC008397.7         19338-19481         c
FEATURES             Location/Qualifiers
     source          1..856
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p13.11"
     gene            1..856
                     /gene="CIST1"
                     /note="colon, intestine and stomach enriched 1"
                     /db_xref="GeneID:729966"
                     /db_xref="HGNC:HGNC:55823"
     exon            1..143
                     /gene="CIST1"
                     /inference="alignment:Splign:2.1.0"
     CDS             56..760
                     /gene="CIST1"
                     /codon_start=1
                     /product="uncharacterized LOC729966 precursor"
                     /protein_id="NP_001382965.1"
                     /db_xref="CCDS:CCDS92568.1"
                     /db_xref="GeneID:729966"
                     /db_xref="HGNC:HGNC:55823"
                     /translation="MACPQLPPLLLLVLVVLLKAGVNYNTPFTDIVTSENSMETSPVS
                     SLISSPFAHSTHSSGEPPKSYSSTMSLETDSITHLSPSSSGATPTIQPSPSSTDSRMI
                     PSSPQPETITHPSSGSPSAELTPSSHSTLPSSESLTPHWSPTSHSPGTEPLTSTDQTL
                     EPPGPAPGDTGPRELHRNPSVVVVVCLLVSLLLIGSVVMAVRFCHRNESKFENLDEVS
                     MGSVNDRLSFAHHLQE"
     exon            144..551
                     /gene="CIST1"
                     /inference="alignment:Splign:2.1.0"
     exon            552..712
                     /gene="CIST1"
                     /inference="alignment:Splign:2.1.0"
     exon            713..856
                     /gene="CIST1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      832..837
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CIST1"
                     /note="hexamer: AATAAA"
     polyA_site      856
                     /gene="CIST1"
                     /note="major polyA site"
ORIGIN      
        1 acacacctgg ccacacacct gtgcagagcc ggtggcaggc cctcccggcg caggaatggc
       61 gtgcccccag ctgccgccac ttctgctttt ggtgctggtg gtgctgctga aagctggtgt
      121 gaattacaat actcccttta cagatattgt gacctcagag aacagtatgg agacatcacc
      181 tgtcagctct ctgatttctt ctcccttcgc ccacagcacc cacagttcag gggaaccccc
      241 caaatcctac tccagcacca tgagtttgga gacagactcc ataacccacc tcagcccctc
      301 aagttcaggg gcaaccccta ccatccagcc gagccccagc tccacagatt caaggatgat
      361 accctcctcc ccacaaccag agacaatcac gcaccctagt tctggctccc ccagtgcaga
      421 gctcaccccc tcttcccatt ccaccctccc cagttccgaa tccctgaccc cgcactggag
      481 ccccacttcc cacagccccg gaacggagcc cttgacctcc actgaccaga ccttggagcc
      541 ccctggccca gctccaggtg acactgggcc ccgtgagtta cacaggaacc cgagtgtggt
      601 ggtggtcgtg tgtttgctgg tgtctctttt gctcatcggg tctgtggtca tggctgtgag
      661 attctgtcac cggaatgagt ccaagtttga gaacctggac gaggtgtcca tgggatccgt
      721 gaatgacaga ttgtcctttg cccaccacct ccaggagtga gccctgagga gccaacagag
      781 atgggggcat ggatggggct ggggttcctg gggaggagca gaacctgagg aaataaagcc
      841 cctaccattc atccaa
//
