LOCUS       NM_001080528             704 bp    mRNA    linear   PRI 16-FEB-2025
DEFINITION  Homo sapiens ciliary microtubule inner protein 7 (CIMIP7), mRNA.
ACCESSION   NM_001080528 XM_929422
VERSION     NM_001080528.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 704)
  AUTHORS   Andersen,J.S., Vijayakumaran,A., Godbehere,C., Lorentzen,E.,
            Mennella,V. and Schou,K.B.
  TITLE     Uncovering structural themes across cilia microtubule inner
            proteins with implications for human cilia function
  JOURNAL   Nat Commun 15 (1), 2687 (2024)
   PUBMED   38538594
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC135506.3.
            
            On May 17, 2019 this sequence version replaced NM_001080528.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence because no single transcript was available for the
            full length of the gene. The genomic coordinates used for the
            transcript record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA1968968,
                              SAMEA2148093 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000545770.7/ ENSP00000454903.1
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-114               AC135506.3         122046-122159       c
            115-228             AC135506.3         120326-120439       c
            229-285             AC135506.3         108783-108839       c
            286-704             AC135506.3         107935-108353       c
FEATURES             Location/Qualifiers
     source          1..704
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3p21.31"
     gene            1..704
                     /gene="CIMIP7"
                     /gene_synonym="C3orf84"
                     /note="ciliary microtubule inner protein 7"
                     /db_xref="GeneID:646498"
                     /db_xref="HGNC:HGNC:44666"
     exon            1..114
                     /gene="CIMIP7"
                     /gene_synonym="C3orf84"
                     /inference="alignment:Splign:2.1.0"
     CDS             88..702
                     /gene="CIMIP7"
                     /gene_synonym="C3orf84"
                     /note="uncharacterized protein C3orf84"
                     /codon_start=1
                     /product="ciliary microtubule inner protein 7"
                     /protein_id="NP_001073997.2"
                     /db_xref="CCDS:CCDS58831.1"
                     /db_xref="GeneID:646498"
                     /db_xref="HGNC:HGNC:44666"
                     /translation="MQSALVGSWHNNGFYGHYRSQFKSESAREYHLAAKPQPPAVFLQ
                     RCQEPAQRHFFSKHDNRTSFDKGPYCLLQGIGRRKDLERLWQRHTFLRWAPCEIELRQ
                     QGPLESSYQADFRPGPGLSGLPQHLIHFVQVQPSHTRTTYQQNFCCPSQGGHYGSYKV
                     GPQAPVTDVLPDLPGIPRPKLLQHYLHAGVSECLNWSRALNKDS"
     exon            115..228
                     /gene="CIMIP7"
                     /gene_synonym="C3orf84"
                     /inference="alignment:Splign:2.1.0"
     exon            229..285
                     /gene="CIMIP7"
                     /gene_synonym="C3orf84"
                     /inference="alignment:Splign:2.1.0"
     exon            286..704
                     /gene="CIMIP7"
                     /gene_synonym="C3orf84"
                     /inference="alignment:Splign:2.1.0"
     regulatory      684..689
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CIMIP7"
                     /gene_synonym="C3orf84"
                     /note="hexamer: ATTAAA"
     polyA_site      704
                     /gene="CIMIP7"
                     /gene_synonym="C3orf84"
                     /note="major polyA site"
ORIGIN      
        1 aaattgacct ccagagattc tctttcctga agataccctc caaaagacaa gaggaaagtt
       61 tgccttttct gctcccttct tggaaagatg caaagtgctt tagtaggctc ctggcacaac
      121 aatggcttct atgggcacta cagaagccaa ttcaagagtg aaagtgctag agaataccac
      181 cttgcagcca agccccagcc tccagcagtg ttcctgcagc gatgtcagga gccggcgcag
      241 cgacacttct tctccaagca cgacaaccgt acttcctttg acaaaggtcc ctattgcctg
      301 ctgcagggaa tcggaaggcg gaaggacctg gagcgcctgt ggcagcggca caccttcctg
      361 cgctgggcac cctgtgagat agagttgcgc cagcaggggc ccctggaatc ttcttaccag
      421 gctgatttca ggccaggccc aggactcagt ggcctccccc agcacctcat ccactttgtg
      481 caggtccagc cttcccatac caggaccacc taccagcaga acttctgctg cccatcccag
      541 ggtggccact atggcagcta caaggtaggg ccccaggcgc cggtcactga cgtactgcct
      601 gacctcccag ggatcccaag acccaagctg ctgcagcact accttcatgc tggggtctct
      661 gagtgtctaa actggtccag agcattaaac aaggacagct gaca
//
