LOCUS       NM_001163857            1058 bp    mRNA    linear   PRI 19-SEP-2024
DEFINITION  Homo sapiens ciliary microtubule inner protein 4 (CIMIP4),
            transcript variant 1, mRNA.
ACCESSION   NM_001163857
VERSION     NM_001163857.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1058)
  AUTHORS   Xia,M., Xia,J., Niu,C., Zhong,Y., Ge,T., Ding,Y. and Zheng,Y.
  TITLE     Testis-expressed protein 33 is not essential for spermiogenesis and
            fertility in mice
  JOURNAL   Mol Med Rep 23 (5) (2021)
   PUBMED   33760102
  REMARK    GeneRIF: Testis-expressed protein 33 is not essential for
            spermiogenesis and fertility in mice.
REFERENCE   2  (bases 1 to 1058)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   3  (bases 1 to 1058)
  AUTHORS   Puri,P., Acker-Palmer,A., Stahler,R., Chen,Y., Kline,D. and
            Vijayaraghavan,S.
  TITLE     Identification of testis 14-3-3 binding proteins by tandem affinity
            purification
  JOURNAL   Spermatogenesis 1 (4), 354-365 (2011)
   PUBMED   22332119
REFERENCE   4  (bases 1 to 1058)
  AUTHORS   Collins,J.E., Wright,C.L., Edwards,C.A., Davis,M.P., Grinham,J.A.,
            Cole,C.G., Goward,M.E., Aguado,B., Mallya,M., Mokrab,Y.,
            Huckle,E.J., Beare,D.M. and Dunham,I.
  TITLE     A genome annotation-driven approach to cloning the human ORFeome
  JOURNAL   Genome Biol 5 (10), R84 (2004)
   PUBMED   15461802
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            Z73420.1, BI827796.1, DB447439.1, Z82180.19 and BE502000.1.
            
            On Nov 22, 2018 this sequence version replaced NM_001163857.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: ERR279840.4035.1, CR456416.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000381821.2/ ENSP00000371243.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-15                Z73420.1           6877-6891           c
            16-20               BI827796.1         1-5
            21-21               Z73420.1           6871-6871           c
            22-44               BI827796.1         6-28
            45-49               DB447439.1         3-7
            50-123              Z73420.1           6769-6842           c
            124-183             Z73420.1           3006-3065           c
            184-650             Z73420.1           877-1343            c
            651-795             Z82180.19          35076-35220         c
            796-906             Z82180.19          26717-26827         c
            907-1027            Z82180.19          26392-26512         c
            1028-1058           BE502000.1         9-39                c
FEATURES             Location/Qualifiers
     source          1..1058
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="22"
                     /map="22q12.3"
     gene            1..1058
                     /gene="CIMIP4"
                     /gene_synonym="C22orf33; cE81G9.2; EAN57; TEX33"
                     /note="ciliary microtubule inner protein 4"
                     /db_xref="GeneID:339669"
                     /db_xref="HGNC:HGNC:28568"
                     /db_xref="MIM:620945"
     exon            1..123
                     /gene="CIMIP4"
                     /gene_synonym="C22orf33; cE81G9.2; EAN57; TEX33"
                     /inference="alignment:Splign:2.1.0"
     exon            124..183
                     /gene="CIMIP4"
                     /gene_synonym="C22orf33; cE81G9.2; EAN57; TEX33"
                     /inference="alignment:Splign:2.1.0"
     CDS             162..1004
                     /gene="CIMIP4"
                     /gene_synonym="C22orf33; cE81G9.2; EAN57; TEX33"
                     /note="isoform 1 is encoded by transcript variant 1;
                     protein EAN57; testis-expressed sequence 33 protein;
                     testis-expressed protein 33; testis expressed 33"
                     /codon_start=1
                     /product="ciliary microtubule inner protein 4 isoform 1"
                     /protein_id="NP_001157329.1"
                     /db_xref="CCDS:CCDS54524.1"
                     /db_xref="GeneID:339669"
                     /db_xref="HGNC:HGNC:28568"
                     /db_xref="MIM:620945"
                     /translation="MELGHGAGTTTFTRAHLNDKEGQQDLDPWKAAYSSLDTSKFKNQ
                     GLSSPQPLPLGASAQGSSLGQCHLKEIPPPPPTAASRDSLGMDPQSRSLKNAGSRSSS
                     RENRATSGEGAQPCQGTDDGPSLGAQDQRSTPTNQKGSIIPNNIRHKFGSNVVDQLVS
                     EEQAQKAIDEVFEGQKRASSWPSRTQNPVEISSVFSDYYDLGYNMRSNLFRGAAEETK
                     SLMKASYTPEVIEKSVRDLEHWHGRKTDDLGRWHQKNAMNLNLQKALEEKYGENSKSK
                     SSKY"
     exon            184..650
                     /gene="CIMIP4"
                     /gene_synonym="C22orf33; cE81G9.2; EAN57; TEX33"
                     /inference="alignment:Splign:2.1.0"
     exon            651..795
                     /gene="CIMIP4"
                     /gene_synonym="C22orf33; cE81G9.2; EAN57; TEX33"
                     /inference="alignment:Splign:2.1.0"
     exon            796..906
                     /gene="CIMIP4"
                     /gene_synonym="C22orf33; cE81G9.2; EAN57; TEX33"
                     /inference="alignment:Splign:2.1.0"
     exon            907..1058
                     /gene="CIMIP4"
                     /gene_synonym="C22orf33; cE81G9.2; EAN57; TEX33"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1035..1040
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CIMIP4"
                     /gene_synonym="C22orf33; cE81G9.2; EAN57; TEX33"
                     /note="hexamer: AATAAA"
     polyA_site      1058
                     /gene="CIMIP4"
                     /gene_synonym="C22orf33; cE81G9.2; EAN57; TEX33"
                     /note="major polyA site"
ORIGIN      
        1 acttcccagc aaccatccat tggtcttcac cagtagttct gcagtgggga tctgcacttc
       61 tgggcttcag cacacatcag tgtggttcac gtgtttcctg ctgttatgaa agagattgga
      121 gaggactaag cttggaattg cctgtcccac agcaagaggc tatggagctg ggccacggag
      181 caggtacaac cactttcacc agggcccatc tgaatgacaa ggagggccaa caggacttgg
      241 acccctggaa agcggcctac agttccttgg acacctccaa gttcaagaac cagggtctgt
      301 catccccaca gcccctgccc ctgggagcca gcgctcaagg cagctcccta gggcagtgcc
      361 acttgaagga gattccccct ccacccccga ctgctgccag cagggattct ctgggcatgg
      421 acccacagtc caggtccctg aagaatgcgg gctctcgatc ctcctcgaga gagaacaggg
      481 ccacctcggg agagggggct cagccatgcc aggggacgga tgacggtccc agcttggggg
      541 ctcaggacca gaggagcacg cccacgaacc agaagggcag catcattcct aacaacattc
      601 gccacaagtt tgggagcaat gtggtggacc agctggtctc cgaggagcag gctcaaaagg
      661 ctattgatga agtcttcgag ggccagaaaa gggcaagctc atggcccagc aggacccaga
      721 atcctgtgga aatctcctcc gtcttctcag actactatga cctcggctac aacatgcggt
      781 caaacttgtt tcgaggggct gctgaggaga caaagagcct catgaaggct tcttacacac
      841 cagaggtcat tgagaaatca gtgagggact tagaacactg gcatggcagg aagacggatg
      901 atctggggcg gtggcaccag aaaaatgcta tgaacctgaa cttgcagaaa gcactggaag
      961 agaaatatgg agaaaacagc aaatccaaga gctccaagta ctagttttga cacagtagag
     1021 gtgtcttcta ctcaaataaa gtgctaacaa taaggaaa
//
