LOCUS       XM_005254750            3706 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens CHRNA7 (exons 5-10) and FAM7A (exons A-E)
            fusion (CHRFAM7A), transcript variant X2, mRNA.
ACCESSION   XM_005254750
VERSION     XM_005254750.4
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000015.10) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_005254750.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3706
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="15"
     gene            1..3706
                     /gene="CHRFAM7A"
                     /gene_synonym="CHRNA7; CHRNA7-DR1; D-10; NACHRA7"
                     /note="CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 1 mRNA, 10 ESTs, 695 long SRA reads, 2
                     Proteins, and 99% coverage of the annotated genomic
                     feature by RNAseq alignments, including 9 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:89832"
                     /db_xref="HGNC:HGNC:15781"
                     /db_xref="MIM:609756"
     CDS             1014..1979
                     /gene="CHRFAM7A"
                     /gene_synonym="CHRNA7; CHRNA7-DR1; D-10; NACHRA7"
                     /codon_start=1
                     /product="CHRNA7-FAM7A fusion protein isoform X2"
                     /protein_id="XP_005254807.1"
                     /db_xref="GeneID:89832"
                     /db_xref="HGNC:HGNC:15781"
                     /db_xref="MIM:609756"
                     /translation="MQEADISGYIPNGEWDLVGIPGKRSERFYECCKEPYPDVTFTVT
                     MRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIM
                     PATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWTRVILLNWCAW
                     FLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNLLYIGFRGLDGVHCVP
                     TPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIANRFRCQDESEAVC
                     SEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA"
ORIGIN      
        1 agccctttcc caggcggtag cgggggcagt ggtgctgttg cccttttaaa ctgcggcttg
       61 acgggagccg cgcctcctgt cggtggagtc ggttataaag ggagcagccc cgcaggccgc
      121 cacatagctc ccgccaagtc ctcggtgccc cttgccattt tccagccgcg ctcccacgag
      181 ggtcacggcg gcggggagag gtggagccgc gagagctcgg ccgggggccc cgcctggtgg
      241 tcgcggccat gacagcggct cgggacaggc tccttttccg cgcccctccc gccggaggtg
      301 aggggaagat gtccatgtcc gggttcaagg ccaaaccgaa gttactggcc tctatcttcc
      361 aggagaacca ggagccacag ccgcggctca cgccccaccg caacattaag attacaagtg
      421 gacacctgag tcagcaggac ctggaatccc agatgagaga gcttatctac acgactcaga
      481 tcttgttgtc acccccatta ttgacaatcc aaaggtgcag aaagcactct gacaaataat
      541 gaaacaacca ccatcggtta aatttgatgc aaaaatattg catctaccag cattttcagt
      601 tataatttct gaaagaccaa gattggaatg actttttgta acaagtgtgc tcgcagatcg
      661 actccagtga gaagagctcg gggacctcct gagccaagct taatctcctt tgctgtttgt
      721 gagtggtggc tggtcaccag gaggtggcca ccaggctcct cctttccccg ctgttccaat
      781 tgctaatcca gcatttgtgg atagctgcaa actgcgatat tgctgatgag cgctttgacg
      841 ccacattcca cactaacgtg ttggtgaatt cttctgggca ttgccagtac ctgcctccag
      901 gcatattcaa gagttcctgc tacatcgatg tacgctggtt tccctttgat gtgcagcact
      961 gcaaactgaa gtttgggtcc tggtcttacg gaggctggtc cttggatctg cagatgcagg
     1021 aggcagatat cagtggctat atccccaatg gagaatggga cctagtggga atccccggca
     1081 agaggagtga aaggttctat gagtgctgca aagagcccta ccctgatgtc accttcacag
     1141 tgaccatgcg ccgcaggacg ctctactatg gcctcaacct gctgatcccc tgtgtgctca
     1201 tctccgccct cgccctgctg gtgttcctgc ttcctgcaga ttccggggag aagatttccc
     1261 tggggataac agtcttactc tctcttaccg tcttcatgct gctcgtggct gagatcatgc
     1321 ccgcaacatc cgattcggta ccattgatag cccagtactt cgccagcacc atgatcatcg
     1381 tgggcctctc ggtggtggtg acggtgatcg tgctgcagta ccaccaccac gaccccgacg
     1441 ggggcaagat gcccaagtgg accagagtca tccttctgaa ctggtgcgcg tggttcctgc
     1501 gaatgaagag gcccggggag gacaaggtgc gcccggcctg ccagcacaag cagcggcgct
     1561 gcagcctggc cagtgtggag atgagtgccg tggcgccgcc gcccgccagc aacgggaacc
     1621 tgctgtacat cggcttccgc ggcctggacg gcgtgcactg tgtcccgacc cccgactctg
     1681 gggtagtgtg tggccgcatg gcctgctccc ccacgcacga tgagcacctc ctgcacggcg
     1741 ggcaaccccc cgagggggac ccggacttgg ccaagatcct ggaggaggtc cgctacattg
     1801 ccaaccgctt ccgctgccag gacgaaagcg aggcggtctg cagcgagtgg aagttcgccg
     1861 cctgtgtggt ggaccgcctg tgcctcatgg ccttctcggt cttcaccatc atctgcacca
     1921 tcggcatcct gatgtcggct cccaacttcg tggaggccgt gtccaaagac tttgcgtaac
     1981 cacgcctggt tctgtacatg tggaaaactc acagatgggc aaggcctttg gcttggcgag
     2041 atttgggggt gctaatccag gacagcatta cacgccacaa ctccagtgtt cccttctggc
     2101 tgtcagtcgt gttgcttacg gtttctttgt tactttaggt agtagaatct cagcactttg
     2161 tttcatattc tcagatgggc tgatagatat ccttggcaca tccgtaccat cggtcagcag
     2221 ggccactgag tagtcatttt gcccattagc ccactgcctg gaaagccctt cggagagctc
     2281 cccatggctc ctcaccaccg agacagttgg ttttgcatgt ctgcatgaag gtctacctga
     2341 aaattcaaca tttgcttttt gcttgtgtac aaacccagat tgaagctaaa ataaaccaga
     2401 ctcactaaat cctttccaat aattgactgg tggaaggaaa acaaaaaaca aaaactaaaa
     2461 acctcttagc ttttctgcaa ttcaactttt tatttttatt tttatttcta tcaaagacgg
     2521 tagagagaaa cagcttgatg ctgtttctac atcaaaaaaa aaaaaaaaaa agacagactg
     2581 ttggtcttac taaggatgtt tttaccagcc tgcctgactt ctgcaaacct accctgtcaa
     2641 ggagatcaaa gggacgcagg tttctgttta ttctgaacaa gggccaggcc ccgcggagtg
     2701 tctttggtgg atcccagata actcctaggt gctgctctca gacactgagg agttgagcaa
     2761 atctgttcta ttctgcagaa cccataggac aaataagagt tctactagaa ttaacagccc
     2821 aaaagaatag ctacagctaa gtgaagccac ttacgtgggc tttaaaaaaa taatgtgtta
     2881 gctgattcac atgcactgga gttaattagt cttagaaatg tgtgcatcca tacaaatgca
     2941 caacataaag tgaacatatt cctaggccct ttctgcctgt gtcagggcca ggaagtagag
     3001 gctgggaact cttctggtcc ccagtatggc aggcgccagg gaggggatgg tgtggcccat
     3061 cccttctctg gatacctggc cagtggcagg cagcagggag gagctggccg accctcagtg
     3121 actgacaagc cagcaattct gagttctggc ctttgggagt ctgcctgctc caagccagtc
     3181 caccccagct gcagccccaa aagctggctc aaagtccttg ggtggattca ctggagatgg
     3241 gcaacttaaa acaagagaaa ctttaatttt taaacctaag tgatgataca gctcttccct
     3301 tagattatcg cccaggctgg agtgcagtgg catgatctca gctcactgca agctccacct
     3361 cctgggttca tgccattctc ctgcctcagc ctccccccga gtaactggga atacaggcgc
     3421 ccgccaccat gcctggctaa ttttttgtat ttttagtaga gatagggttt catcatgtta
     3481 gccaggatgg tctcattctt attctttaat gagatcagag ggtaattcac caagaaagac
     3541 ctctcctgtt ccattgtgtc atccaacaac tgctcagagc tcaaaattat agaaggcttc
     3601 tgagccccta gagattttta atttgcttct aatccctgag gtgggaacat catgagggaa
     3661 gatttgattt tcagagttaa ataaattgta tgtgcttttc cagcca
//
