LOCUS       XM_011533576            2472 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens charged multivesicular body protein 2B
            (CHMP2B), transcript variant X1, mRNA.
ACCESSION   XM_011533576
VERSION     XM_011533576.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000003.12) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011533576.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2472
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
     gene            1..2472
                     /gene="CHMP2B"
                     /gene_synonym="ALS17; CHMP2.5; DMT1; FTDALS7; VPS2-2;
                     VPS2B"
                     /note="charged multivesicular body protein 2B; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 16 ESTs, 616 long SRA reads, 6 Proteins, and 96%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 88 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:25978"
                     /db_xref="HGNC:HGNC:24537"
                     /db_xref="MIM:609512"
     CDS             49..738
                     /gene="CHMP2B"
                     /gene_synonym="ALS17; CHMP2.5; DMT1; FTDALS7; VPS2-2;
                     VPS2B"
                     /codon_start=1
                     /product="charged multivesicular body protein 2b isoform
                     X1"
                     /protein_id="XP_011531878.1"
                     /db_xref="GeneID:25978"
                     /db_xref="HGNC:HGNC:24537"
                     /db_xref="MIM:609512"
                     /translation="MISAQRNHHLPDSSDSSTSAYRVARITDVIKEQNRELRGTQRAI
                     IRDRAALEKQEKQLELEIKKMAKIGNKEACKVLAKQLVHLRKQKTRTFAVSSKVTSMS
                     TQTKVMNSQMKMAGAMSTTAKTMQAVNKKMDPQKTLQTMQNFQKENMKMEMTEEMIND
                     TLDDIFDGSDDEEESQDIVNQVLDEIGIEISGKMAKAPSAARSLPSASTSKATISDEE
                     IERQLKALGVD"
ORIGIN      
        1 cagagtttcg ctgttgttgc ccaggctgga gtgctggagt gcaatggcat gatctcggct
       61 caacgcaacc atcacctccc agattcaagc gattcttcta cctcagccta ccgagtagct
      121 cggattacag atgtaataaa ggaacagaat cgagagttac gaggtacaca gagggctata
      181 atcagagatc gagcagcttt agagaaacaa gaaaaacagc tggaattaga aattaagaaa
      241 atggccaaga ttggtaataa ggaagcttgc aaagttttag ccaaacaact tgtgcatcta
      301 cggaaacaga agacgagaac ttttgctgta agttcaaaag ttacttctat gtctacacaa
      361 acaaaagtga tgaattccca aatgaagatg gctggagcaa tgtctactac agcaaaaaca
      421 atgcaggcag ttaacaagaa gatggatcca caaaagacat tacaaacaat gcagaatttc
      481 cagaaggaaa acatgaaaat ggaaatgact gaagaaatga tcaatgatac acttgatgac
      541 atctttgacg gttctgatga cgaagaagaa agccaggata ttgtgaatca agttcttgat
      601 gaaattggaa ttgaaatttc tggaaagatg gccaaagctc catcagctgc tcgaagctta
      661 ccatctgcct ctacttcaaa ggctacaatc tcagatgaag agattgaacg gcaactcaag
      721 gctttaggag tagattagtc aaaagaagtc atactatttt gcttacttat aattatgtag
      781 tataaaccaa gcacagtgca gatttctttt acaaaacaca tgtattttgc aaaaaaaaaa
      841 aaaatgaaga ccatgagtga acagttgttt cctaacccat ggctatttag aatcttttgc
      901 caaagaatga caatgatgca aaaatgggaa cagtttggat tttaattaga actgtttagg
      961 agtgatgatg tgtaaaaagt tgacttctct tttgcatggc acagagaaat tatattcctt
     1021 acttcatgtc agtttatgtt ctaaatcttt ttcactgaat ataaaaatct tgttaaatgc
     1081 cattaggcac caacttaaag agggttgtaa aaatattaaa agtatatcgt taattctgta
     1141 tctgttgctt gtcttttgta agtgattatg tgttatgacc ataggtggtt acagctgcca
     1201 aattattttt aaatggtcaa aaagaagagt gctatttaaa catctgtctt aaacaaaaac
     1261 tgtcataact tttctttttt ctttttccat taggagaaca ttctagttgg taaatttcaa
     1321 aatgtgcttg acacctgcct taaatagcac agacctattg tgcacatctt taaattattt
     1381 cagctggcag aaaagaatta catttaaaac tgaaatcaag gcctcaatac aaagattatc
     1441 ctggctcttt tctatctctg tgggcctaat tgaaatatgt actcttattt tagacacgcc
     1501 tctgttaaaa cagaccaggt tttcctggtc tcagacctat gatgacttgt ccctttgatg
     1561 tcactactgt gaattgaata taattagtaa aaatagacga tgaataaata acactttata
     1621 gtaagaaaac aatatatttt ggccatctaa aaatgagaat tataattata tgaattataa
     1681 tttaaactgt ttaattttgt ttaatgtgta tattgaatct tccaaattga agccattatt
     1741 ctcaattaag tactacaact atgacaatgc ttgacctaca tttctaaaat aaaaattcac
     1801 attttttgat aaataaacta cagttttacc agaaattact atctaaatgt gtattagcag
     1861 tattttttaa ggtgaaattg ccttggtatc taatgaatgt gtagacaggg agataaaatg
     1921 aaggattgcc agactagtta gaatagaatt taggattagg ttagttttga aaaatgatgt
     1981 tgtaatatat gggttctaac acatcctacc ataaaaactg gaggagatat gtgtaacctg
     2041 gttaatttgg gatggtggac attttgggct aatactgaca aaatacatct taggactagt
     2101 atacatgtga cacggattgc taggaggaat gaaaaactaa actgtatagt ttatattccg
     2161 taaaccattt tataatgttc aaagattagg ttttgttatt gatagtatta aatacacagt
     2221 ttctcttaac agtgatgggt gaaaacattt taccggatta tggaatgttt accagaacat
     2281 gttttgattc ttgaatgtac ataataatgc catctaactt atttacgttc ttgtttacat
     2341 gtgggagctt ttgttttcaa aaattatttt gttaaaaaat ctcaataaag atttattatt
     2401 gttgttcttt tcttaccttt tttgctcttt ttggttcctg ctaaaattaa aaattttatg
     2461 catatttggt aa
//
