LOCUS       XM_047426321            6824 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens choline kinase alpha (CHKA), transcript
            variant X6, mRNA.
ACCESSION   XM_047426321
VERSION     XM_047426321.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000011.10) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6824
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
     gene            1..6824
                     /gene="CHKA"
                     /gene_synonym="CHK; CK; CKI; EK; NEDMIMS"
                     /note="choline kinase alpha; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 18
                     ESTs, 79 long SRA reads, and 84% coverage of the annotated
                     genomic feature by RNAseq alignments, including 28 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:1119"
                     /db_xref="HGNC:HGNC:1937"
                     /db_xref="MIM:118491"
     CDS             5808..6758
                     /gene="CHKA"
                     /gene_synonym="CHK; CK; CKI; EK; NEDMIMS"
                     /codon_start=1
                     /product="choline kinase alpha isoform X5"
                     /protein_id="XP_047282277.1"
                     /db_xref="GeneID:1119"
                     /db_xref="HGNC:HGNC:1937"
                     /db_xref="MIM:118491"
                     /translation="MVLESVMFAILAERSLGPKLYGIFPQGRLEQFIPSRRLDTEELS
                     LPDISAEIAEKMATFHGMKMPFNKEPKWLFGTMEKYLKEVLRIKFTEESRIKKLHKLL
                     SYNLPLELENLRSLLESTPSPVVFCHNDCQEGNILLLEGRENSEKQKLMLIDFEYSSY
                     NYRGFDIGNHFCEWMYDYSYEKYPFFRANIRKYPTKKQQLHFISSYLPAFQNDFENLS
                     TEEKSIIKEEMLLEVNRFALASHFLWGLWSIVQAKISSIEFGYMYPNVVTWWHQDSVA
                     QPRKPGEKPLSLMLWLPLEVALTSRPADLASPASEKCLQS"
ORIGIN      
        1 agacagcctc ccactgtcgc ccaagctaga gtgcaatggc gtgatcttag ctcgcggcaa
       61 cctctgcctc tcaggttcaa gcgattctta tgcctcagtc ccctgagtag ctgggattac
      121 aggcatgtgc cactatacct gactaatttt tgtattttaa gtagagacag ggtttcacca
      181 tgttggtcag gctggtctca aattcccaac ctcaggtgat ccacccacct cggcctccca
      241 acgtgctggg attacaggcg tgagccactg cacccagaca ggattattct tacttattta
      301 tttataggtc tcaaagcatt tttaaaaggt cacaatcaat ctaccgtttt atgtaaagcc
      361 tttaaaagag acagtaagct gaatgatcca tttagttatt ttttggtgag gaaggggtgg
      421 taggaagaag agaatgtcat ccatgtttct taattttctt tttttgtgtg tatttttctt
      481 tttttctatt aaaaaatgga tggcacaatt ttttttctat aaaaaacctg tactcttatt
      541 tatatatcat tttagttcag cagccaccat tatatttaac atagtaccta tttctattct
      601 atattatgat ttttttgtgt gtgtgtgtga gatgaagtct cactctattg cccaggctgg
      661 agtgcagtgg tgtgatcttg gctcactaca atctctgcct cccaggttca agcgattctc
      721 ccgcctcagc cttccaagta gctgagatta caggcacttg ccaccagacc cggctaattt
      781 ttttgtattt ttagtagaga ttgggtttca ccatgttggc caggatggtt ttgaactcct
      841 gacctcaaat gatccgcccc cctcaacctc ccaaagtgct aaggttacca atgtgagcca
      901 ccatgcctgg ctcatattat attatccata attgataatg atttcgtttc ttaaatagca
      961 tttccaattt attttgctat tgatgacatg ctattctttg tagctgattc atcacttttt
     1021 aaaatctgtc tcacagcagc tcatgtagta ttggacgttt aaagatactt tgaagataaa
     1081 tgttttgggt gttaaagatg ttttaaatga catttttttt ttttgagacg gagtctcgct
     1141 ctgtcgccca ggctggagtg aagtggcacg atctctgctc actgcaagct ccgcctcccg
     1201 ggttcacgcc attctcctgc ctcagcctcc cgagtagctg ggacaacagg cgcccgccac
     1261 cgcgccaggc aattttttgt atttttagta gagacggtgt ttcactgtgt cagccaggat
     1321 ggtctcaatc ccctgacctc gtgatccgcc catcttggcc tcccaaagtg ttgggattac
     1381 aggcgtgagc caccacgccc agccaaatga catttaaatg ataactatat gtgacttaat
     1441 gacactttct ttatgccgct ttcacccatt cttactatac acagactcta gggaaaactg
     1501 aggtgctgct ttgttttcat ctcccaaatg gggctttatt catttagtca taaacctact
     1561 tccctcagta ttagagaagt ctttcattaa gtactggcca aataagttta ttctgtctga
     1621 tggcttaaat aggttaaaag aaatatacct gctatattgt ggaacattag gtaacttaaa
     1681 gtaggttttt gaatcctaaa atcatataac acaaaataca ataaagggac atctcttcct
     1741 ccttggtcct ggagttgtct taccacttat tgattttttt tattgtattt ttattttatg
     1801 agacagagtc tcgctgtcgc caggctgggg tgcagtggcg cgatcttggc tcactgcaac
     1861 ctcggcctcc tgggttcaag tgattctcct gcctcagctt cccgagtagc tgagacttac
     1921 aggcgcacat caccacaccc agctaatttt tgtattttta gtagagaagg ggtttcacca
     1981 tgttggcaag gatggtgtcg atctcttgac ctcgtgatcc gcctgcctcg gcctcccaaa
     2041 gtgttgggat tacaggcgtg agccaccgtg cctggcccat tttattttta aagcatgaag
     2101 tagaacattt tgaaaacctg tgctctgtaa tatgaatatt tactgctttt catagtctca
     2161 tttaaaatac aaagcctaaa tagccgggcg tggtggcaca cacctgtaat cccaactatt
     2221 ccggaggctg aggtgggaga atcgcttgaa cccaggaggt ggaggttgca gtgagctgag
     2281 attgcaccac tgcactctag cctgggtgac agagtgagac gctgtctcaa aaacaaaaaa
     2341 caaaacaaac aaaaaaaccc caaagcctta aattgcaatt ttgttagaaa agtaacattt
     2401 gaaaccttgt atcaaatgta tttattataa aaataataca cgcttttaag cactttttaa
     2461 agtatagaaa taaagtaaaa atgaaagtcc tctattttct cattttactc catagctaat
     2521 ataattcaga ctttcaggaa tttagttttt aaatttaaaa gttcttggcc aatcaaaaaa
     2581 tctttttcag gctggtcatg gtggctcatg cctgtaatct cagccctttg ggagactgtg
     2641 gcaggaggat cacttgagct caggaattca agagcagcct gggtaacata gtgagatctt
     2701 gtctctacaa gaaaaaaaaa aaggctaggt atggtggcac atgcctgtgg tcctgctact
     2761 tgggaggcta atacaggagg attgctcgac ctggggaggt tgaggctgca gtgagcccta
     2821 ttcctgccac tgcactccaa cctgagagac agagcgagac ccagtctcca aatttttttt
     2881 ttaaagtttc acctcttaaa agctaacttt aaaatagtaa gtatgcctcc tttattaatg
     2941 ctgtcactgt agcctcattt gtttcctaca tcacaggcta atgaatatat gactctaact
     3001 taagattctc ttgaaaacta agcccaaaat aggaaggaaa gaaagaaggt gggaggaagc
     3061 cagtggcaat atatttttca ttattgtgtg ccttttaagt gtagaattca gtggttttca
     3121 gtgtatttat ggagttgggt gtcttaggca taattgagac attctgattt cttaggtctt
     3181 gaaatttcaa tgtttatttt ttaaaagttt ttattatggg gaatttcaga tataccctaa
     3241 agtagaagag tataatgaac cccagtgtcc attcctcatc ttcccctcac agccagtctt
     3301 cttccatctt ttccctcatt tactccacca gggttatttt gaagcaaatt ccagatgtta
     3361 tattattctg taaatatttc agtctgtatc tatataagat gattttttaa aaatgaccac
     3421 agtaatgttc acattaaaaa aatttaataa ttacttaata ttaaataacc agtgttcaaa
     3481 tttctaataa atgtaaaaag cttagttttg ttttataact tatagaggat aatttttatt
     3541 aacttgttag agaaaagttg gatgtcatac taaatattta tacaatgtat tttaatatct
     3601 acttcaaatg aatttatgtc actgaagtaa aatcccacgg attcctatat atatatacac
     3661 acatatatat acgtatatat atgtgtatat atatatacac atatatacgt atatgtgtgt
     3721 atatatatac acatatacgt atatatgtgt atatatatat acacatatat atacgtatat
     3781 gtgtatatat atacacatgt atatacacat atacgtatat atatgtgtat atatacgtat
     3841 atatgtattt tttttttttt ttgagtcaga gttttgctct tgtcacccag gctggagtgc
     3901 agtggcgtga tcttggctca ctacaacctc ttcttcccgg attcaagcga ttctcctgcc
     3961 tcagcctcct gagtagctgg gattacaggc atgcgccact atgcccggct aatttttttg
     4021 tatttttagt agagttggag tttcaccatg ttggccaggc tgatctcaag ctcctgacct
     4081 gagatgatcc acctgcctca gcctcccaaa gtgctgggat tacaggcatg ggccaccccc
     4141 gccggcccca aaatatattt aacttcctgt cttcctggac gaaaaagtta ttctcttacc
     4201 tttccatgaa tatacacttg gtttgagatt tcctcgtctt acacttctta tttacaggac
     4261 ttagggagcc tgaacattct gtactgagga aacagaacag agggctggat attgcagaag
     4321 tccatcttgc cttcataatg gtgctcttat ggtataagtg atgaattcat ctgggggtgg
     4381 agtgagggag tgggcagggg agattatcat ggatttacta ccacttatag tgccaatatg
     4441 tttaaaaaaa ggaaagactt tggggcctca gccaattttt aactttggat gaagtaactt
     4501 gcttttgcga gcgccattag ataagggaaa gggacttctg aaggctaaat aacccattaa
     4561 ctgtatctcc ctaagaagat acagttagag taacaacagc ataggaataa ccatagtcat
     4621 ttagaattgt gtacaggtca aatcccgtta caacaatttc agaagagtat ctaacttatt
     4681 tgtcttaaag cttatactgc aaagtattaa tatgtaatat atcagattat agaacttttt
     4741 tgttcttaag tttctttgga gaaaaaaaca caaggacttt tgaaggggca tttctaatta
     4801 accccacagc cagcttcctt gttaccaaga ccctggatgg gaatttgcta tcactggttg
     4861 gctgcgtggc accaggcagc tcgttgggct cacttgcctc gtgctatacc actccggagt
     4921 gttcatttat tcatgcagcc taaaaagtgt agtgggcatc gagatttgct tggtgctctg
     4981 ggagaagact aacatcaata aaagacgcag tccctattca ttaggaattt acagactgct
     5041 tggaagaggc gacccgcaaa gcagagtcta aggaacgatg cggccacgag agtgtttgga
     5101 attagggtga agggaagctt tccagcgcct accacatcgc acatcaaacc atctgcaaag
     5161 atctgaaagc atttttgtag tattttgatt tttatagctt tcattgtaac gggatttaac
     5221 ctgtaacatc ttttcatcag agaactgcag attacacaaa tgaaaatatc ataaatcccc
     5281 atttgtactt tctgtacttt gtaccaaatg tacttaactg tatgctaaat atagtattga
     5341 atatgtatca gtgcaaacgt taagagcctt ttgcaaatag atttatgaac atggatactt
     5401 attttgttta cttttatatt acatgtactg tttatacaaa acatgcatta aaacgtctgt
     5461 aatgttattt cagtgtgtga tggatgagtg gttgctttaa atcactaggt ttttgattgg
     5521 tgctagagta gctggtgttg cttaacgtgg catttttttt cctgtccaca ctttccaccc
     5581 ttggtacagg tatttttgat aaagctgtgg aatggaaagg ttgacttgag agaaccacgt
     5641 agctaaattg gtgagagact cagcctgacc gcttgtcttt agaaggcctg attggaagag
     5701 tgcactctat tgactttcct ctaacaatga aattgtgaaa gaggtcctgt aataaagagg
     5761 gatccgaaca agctcagaaa gaaaatgaat ttcaaggggc tgaggccatg gttctggaga
     5821 gcgttatgtt tgccattctc gcagagaggt cacttgggcc aaaactctat ggcatctttc
     5881 cccaaggccg actggagcag ttcatcccga gccggcgatt agatactgaa gaattaagtt
     5941 tgccagatat ttctgcagaa atcgccgaga aaatggctac atttcatggt atgaaaatgc
     6001 cattcaataa ggaaccaaaa tggctttttg gcacaatgga aaagtatcta aaggaagtgc
     6061 tgagaattaa atttactgag gaatccagaa ttaaaaagct ccacaaattg ctcagttaca
     6121 atctgccctt ggaactggaa aacctgagat cattgcttga atctactcca tctccagttg
     6181 tattttgtca taatgactgt caagaaggta atatcttgtt gctggaaggc cgagagaatt
     6241 ctgaaaaaca gaaactgatg ctcattgatt tcgaatacag cagttacaat tacaggggat
     6301 tcgacattgg aaatcacttc tgtgagtgga tgtatgatta tagctatgaa aaataccctt
     6361 ttttcagagc aaacatccgg aagtatccca ccaagaaaca acagctccat tttatttcca
     6421 gttacttgcc tgcattccaa aatgactttg aaaacctcag tactgaagaa aaatccatta
     6481 taaaagaaga aatgttgctt gaagttaata ggtttgccct tgcatctcat ttcctctggg
     6541 gactgtggtc cattgtacaa gccaagattt catctattga atttgggtac atgtacccga
     6601 atgtggtgac ctggtggcat caggacagtg tggctcagcc caggaagccg ggggagaagc
     6661 cgctgtcact gatgctgtgg ttgcctttgg aggttgccct cacttccagg ccagctgacc
     6721 ttgcctcccc tgcttcagag aagtgcctgc aatcctgatg gggaatgtag gcatctgcac
     6781 cctcgaagtc cagctctgac ctcagtccct tctgacacgg gaca
//
